Published in Environ Health Perspect on July 01, 2000
Comparative cellular toxicity of hydrophilic and hydrophobic microcystins on Caco-2 cells. Toxins (Basel) (2012) 0.99
Hepatotoxic seafood poisoning (HSP) due to microcystins: a threat from the ocean? Mar Drugs (2013) 0.86
Time-dependent oxidative stress and histopathological changes in Cyprinus carpio L. exposed to microcystin-LR. Ecotoxicology (2011) 0.85
The interactive effects of cytoskeleton disruption and mitochondria dysfunction lead to reproductive toxicity induced by microcystin-LR. PLoS One (2013) 0.84
Microcystin-LR induced reactive oxygen species mediate cytoskeletal disruption and apoptosis of hepatocytes in Cyprinus carpio L. PLoS One (2013) 0.83
The possible role of cyanobacterial filaments in coral black band disease pathology. Microb Ecol (2013) 0.83
Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells. J Zhejiang Univ Sci B (2011) 0.77
Functional categorization of transcriptome in the species Symphysodon aequifasciatus Pellegrin 1904 (Perciformes: Cichlidae) exposed to benzo[a]pyrene and phenanthrene. PLoS One (2013) 0.77
Oxidative stress and histopathological alterations in liver of Cyprinus carpio L. induced by intraperitoneal injection of microcystin-LR. Ecotoxicology (2015) 0.75
A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem (1976) 5.38
Mechanisms of regulating tubulin synthesis in cultured mammalian cells. Cell (1979) 3.19
Liver failure and death after exposure to microcystins at a hemodialysis center in Brazil. N Engl J Med (1998) 2.88
The toxins of cyanobacteria. Sci Am (1994) 2.69
Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. J Biol Chem (1990) 2.16
Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin. Cell (1990) 2.08
Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil. Lancet (1998) 2.06
Role of tubulin-SH groups in polymerization to microtubules. Functional-SH groups in tubulin for polymerization. J Biochem (1974) 1.56
Primary prevention of hepatocellular carcinoma. J Gastroenterol Hepatol (1996) 1.40
Cytoskeletal integrity in interphase cells requires protein phosphatase activity. Proc Natl Acad Sci U S A (1992) 1.36
Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication. Biochim Biophys Acta (1998) 1.35
Phosphorylation determines the binding of microtubule-associated protein 2 (MAP2) to microtubules in living cells. J Cell Biol (1991) 1.28
Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases. Biochem Biophys Res Commun (1990) 1.27
Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch Biochem Biophys (1984) 1.23
Protein phosphatases maintain the organization and structural interactions of hepatic keratin intermediate filaments. J Cell Sci (1997) 1.08
Rapid microfilament reorganization induced in isolated rat hepatocytes by microcystin-LR, a cyclic peptide toxin. Exp Cell Res (1989) 1.05
New aspects of glutathione biochemistry and transport: selective alteration of glutathione metabolism. Fed Proc (1984) 0.98
Formation, characterization, and toxicity of the glutathione and cysteine conjugates of toxic heptapeptide microcystins. Chem Res Toxicol (1992) 0.94
Alterations in cytoskeletal protein sulfhydryls and cellular glutathione in cultured cells exposed to cadmium and nickel ions. Toxicology (1993) 0.93
Genotoxicity of microcystic cyanobacteria extract of a water source in China. Mutat Res (1999) 0.91
Effects of sodium arsenite on the cytoskeleton and cellular glutathione levels in cultured cells. Toxicol Appl Pharmacol (1992) 0.89
Studies on oxidative damage induced by cyanobacteria extract in primary cultured rat hepatocytes. Environ Res (1998) 0.89
Peroxide-induced membrane blebbing in endothelial cells associated with glutathione oxidation but not apoptosis. Am J Physiol (1999) 0.88
Alterations in microtubules, intermediate filaments, and microfilaments induced by microcystin-LR in cultured cells. Toxicol Pathol (1995) 0.86
The highly reducing sugar 2-deoxy-D-ribose induces apoptosis in human fibroblasts by reduced glutathione depletion and cytoskeletal disruption. Biochem Biophys Res Commun (1998) 0.86
A tumour promoter induces alterations in vinculin and actin distribution in human renal epithelium. J Pathol (1992) 0.86
Detection and identification of metabolites of microcystins formed in vivo in mouse and rat livers. Chem Res Toxicol (1996) 0.83
Comparison of in vivo and in vitro toxic effects of microcystin-LR in fasted rats. Toxicon (1989) 0.83
Paraquat induces actin assembly in depolymerizing conditions. FASEB J (1997) 0.80
Toxicity and kinetics of [3H]microcystin-LR in isolated perfused rat livers. Toxicol Appl Pharmacol (1991) 0.80
Toxicity evaluation of in vitro cultures of freshwater cyanobacterium Microcystis aeruginosa: I. Hepatotoxic and histopathological effects in rats. Biomed Environ Sci (1995) 0.79
Relationship between 1-chloro-2,4-dinitrobenzene-induced cytoskeletal perturbations and cellular glutathione. Cell Biol Toxicol (1989) 0.78
Microcystic cyanobacteria causes mitochondrial membrane potential alteration and reactive oxygen species formation in primary cultured rat hepatocytes. Environ Health Perspect (1998) 0.77
Environmental and biological monitoring of occupational exposure to 1,1,1-trichloroethane. Occup Med (Lond) (1995) 4.83
Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice. Development (1995) 3.19
AFM indentation study of breast cancer cells. Biochem Biophys Res Commun (2008) 2.78
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development (1994) 2.71
Statistical evaluation of agreement between two methods for measuring a quantitative variable. Comput Biol Med (1989) 2.22
Phytophotodermatitis due to the application of citrus hystrix as a folk remedy. Br J Dermatol (1999) 1.80
Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore. Am J Clin Nutr (2001) 1.45
Deformability study of breast cancer cells using microfluidics. Biomed Microdevices (2009) 1.36
Cis-acting sequences that affect somatic hypermutation of Ig genes. Immunol Rev (1998) 1.28
Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HepG(2) cells. Cancer Lett (2000) 1.28
Thiamine deficiency and sudden deaths: lessons from the past. Lancet (1990) 1.23
Neurophysiological studies on workers exposed to lead. Br J Ind Med (1985) 1.22
Somatic hypermutation of immunoglobulin genes is linked to transcription. Curr Top Microbiol Immunol (1998) 1.20
Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE-cadherin. Nat Commun (2013) 1.20
Renal tubular function of workers exposed to low levels of cadmium. Br J Ind Med (1989) 1.19
Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1. Free Radic Biol Med (1996) 1.17
Lead exposure patterns and parameters for monitoring lead absorption among workers in Singapore. Ann Acad Med Singapore (1982) 1.16
Vitamins, selenium, iron, and coronary heart disease risk in Indians, Malays, and Chinese in Singapore. J Epidemiol Community Health (1998) 1.16
Interaction of calcium and lead in human erythrocytes. Br J Ind Med (1980) 1.11
Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis. Mutat Res (1996) 1.08
Sodium selenite-induced oxidative stress and apoptosis in human hepatoma HepG2 cells. Int J Cancer (1999) 1.08
Neuropsychological studies on lead workers in Singapore. Br J Ind Med (1986) 1.08
Critical role of reactive oxygen species and mitochondrial permeability transition in microcystin-induced rapid apoptosis in rat hepatocytes. Hepatology (2000) 1.07
Lead exposure among small-scale battery recyclers, automobile radiator mechanics, and their children in Manila, the Philippines. Environ Res (2000) 1.07
Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation. Cell Death Differ (2010) 1.07
Trace elements in blood and seminal plasma and their relationship to sperm quality. Reprod Toxicol (1994) 1.05
Urinary trans,trans-muconic acid determined by liquid chromatography: application in biological monitoring of benzene exposure. Clin Chem (1993) 1.05
Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. J Androl (2000) 1.03
Aflatoxin B1-induced lipid peroxidation in rat liver. Toxicol Appl Pharmacol (1994) 1.02
Molecular aspects of somatic hypermutation of immunoglobulin genes. Cold Spring Harb Symp Quant Biol (1999) 1.02
Detection of oxidative DNA damage in human sperm and the association with cigarette smoking. Reprod Toxicol (1997) 0.99
Ebselen induces apoptosis in HepG(2) cells through rapid depletion of intracellular thiols. Arch Biochem Biophys (2000) 0.99
Male endocrine functions in workers with moderate exposure to lead. Br J Ind Med (1991) 0.99
Urinary N-acetyl-beta-D-glucosaminidase activity in workers exposed to inorganic lead. Occup Environ Med (1994) 0.98
Concentrations of lead in maternal blood, cord blood, and breast milk. Arch Dis Child (1985) 0.98
Distribution of lead-203 in human peripheral blood in vitro. Br J Ind Med (1980) 0.98
Aflatoxin B1-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA. Carcinogenesis (1995) 0.97
Role of intracellular thiol depletion, mitochondrial dysfunction and reactive oxygen species in Salvia miltiorrhiza-induced apoptosis in human hepatoma HepG2 cells. Life Sci (2001) 0.97
Superoxide radical-initiated apoptotic signalling pathway in selenite-treated HepG(2) cells: mitochondria serve as the main target. Free Radic Biol Med (2001) 0.96
Somatic hypermutation of immunoglobulin and non-immunoglobulin genes. Philos Trans R Soc Lond B Biol Sci (2001) 0.96
Evaluation of oxidative DNA damage in human sperm and its association with male infertility. J Androl (2000) 0.95
Cardiovascular risk factors in relation to cigarette smoking: a population-based survey among Asians in Singapore. Atherosclerosis (1998) 0.95
Homocysteine, folate, vitamin B12, and cardiovascular risk in Indians, Malays, and Chinese in Singapore. J Epidemiol Community Health (2000) 0.95
Are salivary immunoglobulin A and lysozyme biomarkers of stress among nurses? J Occup Environ Med (1999) 0.95
beta-Phenylethyl isothiocyanate-mediated apoptosis in hepatoma HepG2 cells. Cell Mol Life Sci (2003) 0.94
Blood concentrations of lead, cadmium, mercury, zinc, and copper and human semen parameters. Arch Androl (1993) 0.94
Cumulative blood lead levels and neurobehavioral test performance. Neurotoxicology (1997) 0.93
Involvement of reactive oxygen species in aflatoxin B1-induced cell injury in cultured rat hepatocytes. Toxicology (1995) 0.92
Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis. J Biol Chem (2000) 0.91
Effect of cadmium and cigarette smoking on human semen quality. Int J Fertil Menopausal Stud (1995) 0.91
Genotoxicity of microcystic cyanobacteria extract of a water source in China. Mutat Res (1999) 0.91
Cardiovascular risk factors in non-insulin-dependent diabetics compared to non-diabetic controls: a population-based survey among Asians in Singapore. Atherosclerosis (1998) 0.90
Protection of salvia miltiorrhiza against aflatoxin-B1-induced hepatocarcinogenesis in Fischer 344 rats dual mechanisms involved. Life Sci (2001) 0.89
High affinity of lead for fetal haemoglobin. Br J Ind Med (1980) 0.89
Intracellular thiol depletion causes mitochondrial permeability transition in ebselen-induced apoptosis. Arch Biochem Biophys (2000) 0.89
Blood and urinary benzene determined by headspace gas chromatography with photoionization detection: application in biological monitoring of low-level nonoccupational exposure. Int Arch Occup Environ Health (1994) 0.89
Endocrine profiles of male workers with exposure to trichloroethylene. Am J Ind Med (1997) 0.89
Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes. Toxicol Appl Pharmacol (2001) 0.89
Studies on oxidative damage induced by cyanobacteria extract in primary cultured rat hepatocytes. Environ Res (1998) 0.89
Cadmium-induced oxidative cellular damage in human fetal lung fibroblasts (MRC-5 cells). Environ Health Perspect (1997) 0.88
Mitochondrial damage by the "pro-oxidant" peroxisomal proliferator clofibrate. Free Radic Biol Med (1999) 0.87
Metals in hair as biological indices for exposure. Int Arch Occup Environ Health (1993) 0.87
Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: a possible role in statin-induced hepatotoxicity? Toxicol Appl Pharmacol (2007) 0.87
A study on occupational exposure to petrochemicals and smoking on seminal quality. J Androl (2001) 0.87
Oxidative burden in prediabetic and diabetic individuals: evidence from plasma coenzyme Q(10). Diabet Med (2006) 0.87
Medical students' exposure to formaldehyde in a gross anatomy dissection laboratory. J Am Coll Health (1992) 0.87
Semen parameters in workers exposed to trichloroethylene. Reprod Toxicol (1997) 0.87
Effects of cigarette smoking on human semen quality. Arch Androl (1995) 0.86
Cumulative concentrations of blood lead and postural stability. Occup Environ Med (1996) 0.86
Impairment of color vision among workers exposed to low concentrations of styrene. Am J Ind Med (1994) 0.86
Reactive oxygen species and caspase activation mediate silica-induced apoptosis in alveolar macrophages. Am J Physiol Lung Cell Mol Physiol (2001) 0.86
Lead-induced nephropathy: relationship between various biological exposure indices and early markers of nephrotoxicity. Am J Ind Med (1995) 0.86
Anti-oxidant ebselen causes the resolution of experimentally induced hepatic fibrosis in rats. J Gastroenterol Hepatol (2001) 0.86
Benzene metabolites enhance reactive oxygen species generation in HL60 human leukemia cells. Hum Exp Toxicol (1996) 0.86
Critical role of reactive oxygen species formation in microcystin-induced cytoskeleton disruption in primary cultured hepatocytes. J Toxicol Environ Health A (2001) 0.85
Determination of plasma ascorbic acid by high-performance liquid chromatography with ultraviolet and electrochemical detection. J Chromatogr (1993) 0.85
Sudden unexplained death syndrome. A review and update. Trop Geogr Med (1992) 0.85
High-performance liquid chromatographic method for routine determination of vitamins A and E and beta-carotene in plasma. J Chromatogr (1992) 0.85
Protective effect of ebselen against hydrogen peroxide-induced cytotoxicity and DNA damage in HepG2 cells. Biochem Pharmacol (1999) 0.85
Simultaneous determination of hydroquinone, catechol and phenol in urine using high-performance liquid chromatography with fluorimetric detection. J Chromatogr (1993) 0.85
Applications of new technology in molecular epidemiology and their relevance to occupational medicine. Occup Environ Med (1999) 0.85
Pivotal role of mitochondrial Ca(2+) in microcystin-induced mitochondrial permeability transition in rat hepatocytes. Biochem Biophys Res Commun (2001) 0.84
Biological monitoring of kidney function among workers occupationally exposed to trichloroethylene. Occup Environ Med (2004) 0.84
Effect of Salvia miltiorrhiza on aflatoxin B1-induced oxidative stress in cultured rat hepatocytes. Free Radic Res (1999) 0.84
Effects of ageing on taxi driving. Ann Acad Med Singapore (1987) 0.83