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1
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Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.
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Diabetes
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2000
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2.50
|
|
2
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Glucose-dependent insulin release from genetically engineered K cells.
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Science
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2000
|
1.52
|
|
3
|
Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats.
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Diabetes
|
2001
|
1.38
|
|
4
|
Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice.
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Proc Natl Acad Sci U S A
|
1999
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1.37
|
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5
|
Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus.
|
J Clin Endocrinol Metab
|
1999
|
1.37
|
|
6
|
Functional GIP receptors are present on adipocytes.
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Endocrinology
|
1998
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1.37
|
|
7
|
Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice.
|
Diabetologia
|
2008
|
1.25
|
|
8
|
Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas.
|
Diabetologia
|
2011
|
1.23
|
|
9
|
Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice.
|
Diabetologia
|
2011
|
1.17
|
|
10
|
Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas.
|
Diabetes
|
1997
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1.16
|
|
11
|
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, regulates fasting glycemia and nonenteral glucose clearance in mice.
|
Endocrinology
|
2000
|
1.08
|
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12
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Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat.
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J Clin Invest
|
1996
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1.05
|
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13
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Activation of the parasympathetic nervous system is necessary for normal meal-induced insulin secretion in rhesus macaques.
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J Clin Endocrinol Metab
|
2001
|
1.05
|
|
14
|
Point mutations in the first and third intracellular loops of the glucagon-like peptide-1 receptor alter intracellular signaling.
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Biochem Biophys Res Commun
|
1996
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0.97
|
|
15
|
New aspects of an old drug: metformin as a glucagon-like peptide 1 (GLP-1) enhancer and sensitiser.
|
Diabetologia
|
2010
|
0.95
|
|
16
|
The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation.
|
Diabetologia
|
2012
|
0.93
|
|
17
|
Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide.
|
Diabetologia
|
2012
|
0.93
|
|
18
|
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes.
|
Cell Death Dis
|
2011
|
0.92
|
|
19
|
Glucose-dependent insulinotropic polypeptide confers early phase insulin release to oral glucose in rats: demonstration by a receptor antagonist.
|
Endocrinology
|
2000
|
0.91
|
|
20
|
Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.
|
Diabetologia
|
2010
|
0.91
|
|
21
|
Effects of dipeptidyl peptidase IV on the satiety actions of peptide YY.
|
Diabetologia
|
2006
|
0.89
|
|
22
|
DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes.
|
Gene Ther
|
2009
|
0.88
|
|
23
|
Reprogramming gut and pancreas endocrine cells to treat diabetes.
|
Diabetes Obes Metab
|
2011
|
0.88
|
|
24
|
Hepatic leptin signalling and subdiaphragmatic vagal efferents are not required for leptin-induced increases of plasma IGF binding protein-2 (IGFBP-2) in ob/ob mice.
|
Diabetologia
|
2011
|
0.87
|
|
25
|
Leptin reduces glucose transport and cellular ATP levels in INS-1 beta-cells.
|
J Mol Endocrinol
|
2004
|
0.86
|
|
26
|
Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver.
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J Mol Endocrinol
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2006
|
0.85
|
|
27
|
Effect of exercise on augmented aortic vasoconstriction in the db/db mouse model of type-II diabetes.
|
Physiol Res
|
2007
|
0.84
|
|
28
|
The enteroinsular axis in dipeptidyl peptidase IV-negative rats.
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Metabolism
|
1996
|
0.83
|
|
29
|
The insulinotropic region of gastric inhibitory polypeptide; fragment analysis suggests the bioactive site lies between residues 19 and 30.
|
Can J Physiol Pharmacol
|
1996
|
0.79
|
|
30
|
Novel alternatively spliced exon in the extracellular ligand-binding domain of the pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1R) selectively increases ligand affinity and alters signal transduction coupling during spermatogenesis.
|
J Biol Chem
|
2001
|
0.78
|
|
31
|
dsAAV8-mediated gene transfer and β-cell expression of IL-4 and β-cell growth factors are capable of reversing early-onset diabetes in NOD mice.
|
Gene Ther
|
2011
|
0.78
|
|
32
|
Menin and GIP are inversely regulated by food intake and diet via PI3/AKT signaling in the proximal duodenum.
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Nutr Diabetes
|
2012
|
0.78
|
|
33
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Glucose-dependent insulinotropic polypeptide as a regulator of beta cell function and fate.
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Horm Metab Res
|
2005
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0.76
|
|
34
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Isolation of a murine glucose-dependent insulinotropic polypeptide (GIP) cDNA from a tumor cell line (STC6-14) and quantification of glucose-induced increases in GIP mRNA.
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Biochim Biophys Acta
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1996
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0.75
|
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35
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The multifaceted potential of glucagon-like peptide-1 as a therapeutic agent.
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Minerva Endocrinol
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2002
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0.75
|
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36
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Antisomatostatin-induced growth acceleration in chinook salmon (Oncorhynchus tshawytscha).
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Fish Physiol Biochem
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1994
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0.75
|