Published in Gene Ther on July 01, 2000
Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proc Natl Acad Sci U S A (2002) 2.00
Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells. Small (2010) 1.23
Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery. J Control Release (2008) 1.22
P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells. Nanomedicine (Lond) (2012) 1.14
Role of integrin alpha(v)beta3 in the early phase of liver metastasis: PET and IVM analyses. Clin Exp Metastasis (2002) 0.99
Silica nanoparticles as a delivery system for nucleic acid-based reagents. J Mater Chem (2009) 0.85
Mesoporous silica nanoparticle delivery of chemically modified siRNA against TWIST1 leads to reduced tumor burden. Nanomedicine (2015) 0.82
Type and composition of surfactants mediating gene transfection of polyethylenimine-coated liposomes. Int J Nanomedicine (2011) 0.80
Cationic microRNA-delivering nanocarriers for efficient treatment of colon carcinoma in xenograft model. Gene Ther (2016) 0.79
A novel polymer-lipid hybrid nanoparticle for efficient nonviral gene delivery. Acta Pharmacol Sin (2010) 0.77
Poly(ethylenimine) conjugated bioreducible dendrimer for efficient gene delivery. J Control Release (2015) 0.77
Development of a successive targeting liposome with multi-ligand for efficient targeting gene delivery. J Gene Med (2011) 0.75
Triolein-based polycation lipid nanocarrier for efficient gene delivery: characteristics and mechanism. Int J Nanomedicine (2011) 0.75
Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. J Mol Evol (1985) 47.78
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61
Evaluation of the maximum likelihood estimate of the evolutionary tree topologies from DNA sequence data, and the branching order in hominoidea. J Mol Evol (1989) 16.24
CONSEL: for assessing the confidence of phylogenetic tree selection. Bioinformatics (2001) 11.90
Evolutionary relationship of archaebacteria, eubacteria, and eukaryotes inferred from phylogenetic trees of duplicated genes. Proc Natl Acad Sci U S A (1989) 8.45
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc Natl Acad Sci U S A (1998) 8.41
Mass screening for lung cancer with mobile spiral computed tomography scanner. Lancet (1998) 6.09
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature (1996) 4.12
Gene transfer to the nucleus and the evolution of chloroplasts. Nature (1998) 3.79
Model of amino acid substitution in proteins encoded by mitochondrial DNA. J Mol Evol (1996) 3.53
IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum. Neurology (2010) 3.34
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res (2000) 3.32
Ribosomal RNA trees misleading? Nature (1993) 3.04
Models of amino acid substitution and applications to mitochondrial protein evolution. Mol Biol Evol (1998) 3.03
Tyrosine phosphorylation of beta-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhes Commun (1994) 2.87
Response of anti-NMDA receptor encephalitis without tumor to immunotherapy including rituximab. Neurology (2008) 2.85
Unmasking of latent hypoparathyroidism in a child with partial DiGeorge syndrome by ethylenediaminetetraacetic acid infusion. Eur J Pediatr (1993) 2.69
Interactions of outer membrane proteins O-8 and O-9 with peptidoglycan sacculus of Escherichia coli K-12. J Biochem (1976) 2.61
Molecular clock of silent substitution: at least six-fold preponderance of silent changes in mitochondrial genes over those in nuclear genes. J Mol Evol (1982) 2.58
Towards resolving the interordinal relationships of placental mammals. Syst Biol (1999) 2.53
Results of three-year mass screening programme for lung cancer using mobile low-dose spiral computed tomography scanner. Br J Cancer (2001) 2.46
Plastid genome phylogeny and a model of amino acid substitution for proteins encoded by chloroplast DNA. J Mol Evol (2000) 2.45
Essential role of the small GTPase Rac in disease resistance of rice. Proc Natl Acad Sci U S A (2001) 2.45
Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. J Biol Chem (1993) 2.40
Evolution of RNA polymerases and branching patterns of the three major groups of Archaebacteria. J Mol Evol (1991) 2.38
Mullerian inhibiting substance in humans: normal levels from infancy to adulthood. J Clin Endocrinol Metab (1996) 2.37
A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor. Nature (1993) 2.33
On the maximum likelihood method in molecular phylogenetics. J Mol Evol (1991) 2.26
Depth of invasion as a predictive factor for cervical lymph node metastasis in tongue carcinoma. Head Neck (1997) 2.21
RNA and protein catalysis in group II intron splicing and mobility reactions using purified components. Biochemistry (1999) 2.20
Retroposon analysis of major cetacean lineages: the monophyly of toothed whales and the paraphyly of river dolphins. Proc Natl Acad Sci U S A (2001) 2.11
Inactivating mutations in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in patients with pseudovitamin D-deficiency rickets. N Engl J Med (1998) 2.11
Proline-directed and non-proline-directed phosphorylation of PHF-tau. J Biol Chem (1995) 2.09
Detection of beta-lactamase production by gram-negative bacteria. J Antibiot (Tokyo) (1976) 2.06
Prognostic value of performance status assessed by patients themselves, nurses, and oncologists in advanced non-small cell lung cancer. Br J Cancer (2001) 2.01
EEC syndrome (ectrodactyly, ectodermal dysplasia and cleft lip/palate) with a balanced reciprocal translocation between 7q11.21 and 9p12 (or 7p11.2 and 9q12) in three generations. Clin Genet (1991) 1.96
A cytoplasmic RNA vector derived from nontransmissible Sendai virus with efficient gene transfer and expression. J Virol (2000) 1.92
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. Am J Hum Genet (1999) 1.87
Changes in distribution of hepatic blood flow induced by intra-arterial infusion of angiotensin II in human hepatic cancer. Cancer (1985) 1.84
The preferential codon usages in variable and constant regions of immunoglobulin genes are quite distinct from each other. Nucleic Acids Res (1979) 1.83
A reverse transcriptase/maturase promotes splicing by binding at its own coding segment in a group II intron RNA. Mol Cell (1999) 1.83
Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor. Nature (1991) 1.83
Evaluation of Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test and Roche PCR-microwell plate hybridization method (AMPLICOR MYCOBACTERIUM) for direct detection of mycobacteria. J Clin Microbiol (1996) 1.82
Detection of a noble gas molecular ion, 36ArH+, in the Crab Nebula. Science (2013) 1.80
Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits. J Biol Chem (1995) 1.79
Long-term effect of tacrolimus therapy in patients with refractory ulcerative colitis. Aliment Pharmacol Ther (2008) 1.77
Incidence of arthro-osteitis in patients with pustulosis palmaris et plantaris. Ann Rheum Dis (1981) 1.77
Conflict among individual mitochondrial proteins in resolving the phylogeny of eutherian orders. J Mol Evol (1998) 1.74
Measurements of serum müllerian inhibiting substance in the evaluation of children with nonpalpable gonads. N Engl J Med (1997) 1.74
Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proc Natl Acad Sci U S A (1999) 1.73
Mechanism of nitric oxide-dependent killing of Mycobacterium bovis BCG in human alveolar macrophages. Infect Immun (1997) 1.73
Efficient gene transfer to airway epithelium using recombinant Sendai virus. Nat Biotechnol (2000) 1.71
GATA3 abnormalities and the phenotypic spectrum of HDR syndrome. J Med Genet (2001) 1.71
Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis (1998) 1.70
Clinical experiences in Sakai City Hospital during the massive outbreak of enterohemorrhagic Escherichia coli O157 infections in Sakai City, 1996. Pediatr Int (1999) 1.69
Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase. Oncogene (2010) 1.68
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am J Pathol (2000) 1.66
A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Ann Neurol (2000) 1.65
Deoxyribonucleic acid analyses of five families with familial inherited thyroid stimulating hormone deficiency. J Clin Endocrinol Metab (1990) 1.64
Effect of acetazolamide reactivity on [corrected] long-term outcome in patients with major cerebral artery occlusive diseases. Stroke (1998) 1.64
Changes in oropharyngeal airway and respiratory function during sleep after orthognathic surgery in patients with mandibular prognathism. Int J Oral Maxillofac Surg (2011) 1.64
Phakomatosis pigmentovascularis type IVa. Arch Dermatol (1985) 1.63
Clinical features of 53 cases with pustulotic arthro-osteitis. Ann Rheum Dis (1981) 1.62
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Mechanical compression of the extracranial vertebral artery during neck rotation. Neurology (2003) 1.59
Compressibility-structure relationship of globular proteins. Biochemistry (1986) 1.58
Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea--hypopnea syndrome. Blood (2001) 1.58
Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils. Clin Exp Allergy (2001) 1.57
Interordinal relationships of birds and other reptiles based on whole mitochondrial genomes. Syst Biol (1999) 1.57
Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis. J Dermatol Sci (2001) 1.56
mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity. EMBO J (1995) 1.54
Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy. Rheumatology (Oxford) (2006) 1.53
Monoclonal antibodies distinctively recognizing the subtypes of inositol 1,4,5-trisphosphate receptor: application to the studies on inflammatory cells. FEBS Lett (1994) 1.52
Purification and biochemical properties of beta-lactamase produced by Proteus rettgeri. Antimicrob Agents Chemother (1980) 1.52
A clue for telangiectasis in systemic sclerosis: elevated serum soluble endoglin levels in patients with the limited cutaneous form of the disease. Dermatology (2006) 1.51
Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells. J Biol Chem (2001) 1.51
Establishment and characterization of a new human mesothelioma cell line (T-85) from malignant peritoneal mesothelioma with remarkable thrombocytosis. Pathol Int (1995) 1.50
Clinical features of 22 cases with "inter-sterno-costo-clavicular ossification". A new rheumatic syndrome. Arch Orthop Trauma Surg (1979) 1.49
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. J Neuropathol Exp Neurol (1999) 1.49
Rodent polyphyly? Nature (1992) 1.49
Enumeration, isolation, and species identification of mycoplasmas in saliva sampled from the normal and pathological human oral cavity and antibody response to an oral mycoplasma (Mycoplasma salivarium). J Clin Microbiol (1986) 1.48
Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene. Neurology (2000) 1.48
Detection of abnormal cardiac adrenergic neuron activity in adriamycin-induced cardiomyopathy with iodine-125-metaiodobenzylguanidine. J Nucl Med (1992) 1.48
Suppression of tumor cell growth by anthocyanins in vitro. Cancer Invest (1995) 1.48
Lymphomatous features of aggressive NK cell leukaemia/lymphoma with massive necrosis, haemophagocytosis and EB virus infection. Histopathology (2000) 1.47
Secondary structure of MS2 phage RNA and bias in code word usage. Nucleic Acids Res (1979) 1.47
Gene expression of erythropoietin in renal cell carcinoma. Intern Med (1999) 1.47
Structure-activity relationship of lipid A: comparison of biological activities of natural and synthetic lipid A's with different fatty acid compositions. J Biochem (1986) 1.47
Structural requirements of lipid A responsible for the functions: a study with chemically synthesized lipid A and its analogues. J Biochem (1985) 1.47
Severe thyrotoxicosis induced by thyroid metastasis of lung adenocarcinoma: a case report and review of the literature. Thyroid (2001) 1.47
Basal cell adenocarcinoma of the salivary glands: comparison with basal cell adenoma through assessment of cell proliferation, apoptosis, and expression of p53 and bcl-2. Cancer (1998) 1.45
Warm water vapour in the sooty outflow from a luminous carbon star. Nature (2010) 1.45
Combined antibacterial activity of amoxicillin with clavulanic acid against ampicillin-resistant strains. Antimicrob Agents Chemother (1980) 1.45
Quantitative genetic variation in CD19 expression correlates with autoimmunity. J Immunol (2000) 1.44
Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors. Receptors Channels (1994) 1.43
IgE plasma cell leukemia successfully treated with combination VAD (vincristine, doxorubicin, dexamethasone) and MP (melphalan, prednisolone) followed by interferon-alpha. Am J Hematol (1994) 1.43
Is a proton pump inhibitor necessary for the treatment of lower-grade reflux esophagitis? J Gastroenterol (1999) 1.43