K Ley

Author PubWeight™ 148.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science 1999 7.13
2 Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc Natl Acad Sci U S A 1997 5.54
3 Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity 1994 5.06
4 Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 2000 4.92
5 RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium. Circulation 2001 3.86
6 Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E) J Cell Biol 1997 3.24
7 Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature 1996 3.11
8 Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J Exp Med 1996 3.04
9 Spontaneous skin ulceration and defective T cell function in CD18 null mice. J Exp Med 1998 2.81
10 Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation 2001 2.70
11 Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient mice. Circ Res 1999 2.60
12 Distinct phenotype of E-selectin-deficient mice. E-selectin is required for slow leukocyte rolling in vivo. Circ Res 1996 2.55
13 Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo. J Clin Invest 1998 2.28
14 The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium. J Clin Invest 2001 2.26
15 Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice. Blood 2001 2.11
16 Noninvasive ultrasound imaging of inflammation using microbubbles targeted to activated leukocytes. Circulation 2000 2.07
17 Delayed onset of inflammation in protease-activated receptor-2-deficient mice. J Immunol 2000 2.03
18 L-selectin: mechanisms and physiological significance of ectodomain cleavage. J Cell Mol Med 2005 2.02
19 Leukocyte rolling in vivo is mediated by P-selectin glycoprotein ligand-1. Blood 1995 2.01
20 CD24 mediates rolling of breast carcinoma cells on P-selectin. FASEB J 1998 1.95
21 Role of beta7 integrins in intestinal lymphocyte homing and retention. Curr Mol Med 2009 1.94
22 How do selectins mediate leukocyte rolling in venules? Biophys J 1992 1.92
23 Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1. J Exp Med 1996 1.85
24 Role of vascular cell adhesion molecule-1 and fibronectin connecting segment-1 in monocyte rolling and adhesion on early atherosclerotic lesions. Circ Res 2000 1.71
25 Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice. Gastroenterology 2001 1.69
26 L-selectin shedding regulates leukocyte recruitment. J Exp Med 2001 1.68
27 Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. J Exp Med 1993 1.68
28 Red cell distribution at microvascular bifurcations. Microvasc Res 1989 1.64
29 Adhesion molecules and atherogenesis. Acta Physiol Scand 2001 1.58
30 Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media Mol Imaging 2006 1.58
31 Leukocyte arrest during cytokine-dependent inflammation in vivo. J Immunol 2000 1.56
32 Rapid leukocyte accumulation by "spontaneous" rolling and adhesion in the exteriorized rabbit mesentery. Int J Microcirc Clin Exp 1991 1.56
33 Mice lacking two or all three selectins demonstrate overlapping and distinct functions for each selectin. J Immunol 1999 1.54
34 Variation in the velocity, deformation, and adhesion energy density of leukocytes rolling within venules. Circ Res 1996 1.49
35 CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein. Blood 1996 1.48
36 The role of inflammation in vascular injury and repair. J Thromb Haemost 2003 1.48
37 Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice. Blood 2001 1.47
38 Generalization of the Fahraeus principle for microvessel networks. Am J Physiol 1986 1.47
39 Blocking P-selectin protects from ischemia/reperfusion-induced acute renal failure. FASEB J 2000 1.45
40 Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles. Circulation 2000 1.43
41 Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement-mediated adherence to activated leukocytes. Circulation 2000 1.39
42 Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow. J Control Release 2009 1.36
43 Relevance of L-selectin shedding for leukocyte rolling in vivo. J Exp Med 1999 1.34
44 Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression. Proc Natl Acad Sci U S A 1998 1.33
45 The CD24/P-selectin binding pathway initiates lung arrest of human A125 adenocarcinoma cells. Cancer Res 2000 1.31
46 Role of primary and secondary capture for leukocyte accumulation in vivo. Circ Res 1998 1.31
47 Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice. Br J Pharmacol 2008 1.30
48 Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo. Am J Physiol 1996 1.29
49 A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion. J Cell Biol 1994 1.27
50 Differential effect of E-selectin antibodies on neutrophil rolling and recruitment to inflammatory sites. Blood 1997 1.20
51 Regulation of E-selectin, P-selectin, and intercellular adhesion molecule 1 expression in mouse cremaster muscle vasculature. Microcirculation 1997 1.19
52 The P-selectin glycoprotein ligand-1 is important for recruitment of neutrophils into inflamed mouse peritoneum. Blood 1997 1.19
53 Dextran sulfate prevents LTB4-induced permeability increase, but not neutrophil emigration, in the hamster cheek pouch. Microvasc Res 1989 1.18
54 Trafficking of natural killer cells. Curr Mol Med 2004 1.14
55 Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure. FASEB J 2001 1.12
56 Severe inflammatory defect and reduced viability in CD18 and E-selectin double-mutant mice. J Clin Invest 2000 1.12
57 P-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver. Am J Physiol 1999 1.12
58 Selectin-independent leukocyte rolling and adhesion in mice deficient in E-, P-, and L-selectin and ICAM-1. Am J Physiol Heart Circ Physiol 2001 1.11
59 The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches. J Immunol 1998 1.11
60 Protection from ischemia-reperfusion induced severe acute renal failure by blocking E-selectin. Crit Care Med 2000 1.09
61 Arterial injury increases expression of inflammatory adhesion molecules in the carotid arteries of apolipoprotein-E-deficient mice. J Vasc Res 1999 1.08
62 Absence of p-selectin, but not intercellular adhesion molecule-1, attenuates neointimal growth after arterial injury in apolipoprotein e-deficient mice. Circulation 2001 1.06
63 Essential role of neutrophils in germ cell-specific apoptosis following ischemia/reperfusion injury of the mouse testis. Biol Reprod 2001 1.04
64 TNF-alpha induces selectin-mediated leukocyte rolling in mouse cremaster muscle arterioles. Am J Physiol 1997 1.00
65 Selectin ligands promote ultrasound contrast agent adhesion under shear flow. Mol Pharm 2006 1.00
66 Gene-targeted mice reveal importance of L-selectin-dependent rolling for neutrophil adhesion. Am J Physiol 1998 1.00
67 L-selectin-dependent leukocyte adhesion to microvascular but not to macrovascular endothelial cells of the human coronary system. Blood 1997 1.00
68 The leukocyte integrin Mac-1 (CD11b/CD18) contributes to binding of human granulocytes to collagen. Exp Cell Res 1995 0.99
69 Topological structure of rat mesenteric microvessel networks. Microvasc Res 1986 0.95
70 Functional characterization of L-selectin ligands on human neutrophils and leukemia cell lines: evidence for mucinlike ligand activity distinct from P-selectin glycoprotein ligand-1. Blood 1998 0.94
71 Effect of oxygen tension on regulation of arteriolar diameter in skeletal muscle in situ. Microvasc Res 1995 0.93
72 Intercellular adhesion molecule-1 is required for chemoattractant-induced leukocyte adhesion in resting, but not inflamed, venules in vivo. Microvasc Res 2000 0.92
73 Changes in macromolecular permeability by intravascular generation of oxygen-derived free radicals. Microvasc Res 1982 0.91
74 Expression of CXCL16 in human T cells. Arterioscler Thromb Vasc Biol 2003 0.91
75 A versatile intravital microscope design. Int J Microcirc Clin Exp 1987 0.91
76 Flow-dependent regulation of arteriolar diameter in rat skeletal muscle in situ: role of endothelium-derived relaxing factor and prostanoids. J Physiol 1995 0.90
77 Segmental differences of microvascular permeability for FITC-dextrans measured in the hamster cheek pouch. Microvasc Res 1986 0.88
78 Venulo-arteriolar communication and propagated response. A possible mechanism for local control of blood flow. Pflugers Arch 1989 0.88
79 Sialyl Lewis(x) (sLe(x)) and an sLe(x) mimetic, CGP69669A, disrupt E-selectin-dependent leukocyte rolling in vivo. Blood 1998 0.86
80 Dermal and pulmonary inflammatory disease in E-selectin and P-selectin double-null mice is reduced in triple-selectin-null mice. Blood 2001 0.85
81 Redistribution of red blood cell flow in microcirculatory networks by hemodilution. Circ Res 1992 0.84
82 Sulfated polysaccharides in inflammation. J Lab Clin Med 1993 0.84
83 Cross-linking of CD18 in human neutrophils induces an increase of intracellular free Ca2+, exocytosis of azurophilic granules, quantitative up-regulation of CD18, shedding of L-selectin, and actin polymerization. J Leukoc Biol 1994 0.84
84 Differential requirements for core2 glucosaminyltransferase for endothelial L-selectin ligand function in vivo. J Immunol 2001 0.84
85 A CD2-green fluorescence protein-transgenic mouse reveals very late antigen-4-dependent CD8+ lymphocyte rolling in inflamed venules. J Immunol 2001 0.82
86 Reduced leukocyte adhesion response and absence of slow leukocyte rolling in interleukin-8 receptor-deficient mice. Microvasc Res 1997 0.82
87 Beta2 integrins mediate protein tyrosine phosphorylation in human neutrophils. J Leukoc Biol 1996 0.81
88 Plugging the leaks. Nat Med 2001 0.81
89 Simulating leukocyte-venule interactions--a novel agent-oriented approach. Conf Proc IEEE Eng Med Biol Soc 2004 0.80
90 Phosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung. Eur Respir J 2009 0.80
91 Noninvasive in vivo magnetic resonance imaging of injury-induced neointima formation in the carotid artery of the apolipoprotein-E null mouse. J Magn Reson Imaging 2000 0.79
92 Activation of the beta2 integrin Mac-1 (CD11b/CD18) by an endogenous lipid mediator of human neutrophils and HL-60 cells. J Cell Sci 1997 0.79
93 [Microcirculation disorders in shock]. Klin Anasthesiol Intensivther 1987 0.77
94 Adhesion molecules in lymphocyte trafficking and colitis. Gastroenterology 2001 0.76
95 Microvascular permeability and blood flow in atrial homografts in the hamster cheek pouch. Int J Microcirc Clin Exp 1984 0.76
96 Peptides derived from the lectin domain of selectin adhesion molecules inhibit leukocyte rolling in vivo. Microcirculation 1996 0.75
97 Morphological and functional aspects of heart homograft adaptation to hamster cheek pouch. Spontaneous pulsatile activity and ultrastructure. Blood Vessels 1984 0.75
98 The New York State Experiment. J Sports Med 1976 0.75
99 [The shortage of nursing personnel from a socio-existentialist viewpoint. Considerations on the shortage and pleading for self esteem]. Krankenpfl Soins Infirm 1991 0.75
100 [The onerous heritage of serving and caring...]. Krankenpfl Soins Infirm 1993 0.75
101 Migrant women: is migration a blessing or a handicap? Situation of migrant women in Switzerland. Int Migr 1981 0.75
102 [Not Available]. Luzif Amor 1993 0.75