Published in Circulation on November 28, 2000
US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology (2008) 3.15
Myocardial ischemic memory imaging with molecular echocardiography. Circulation (2007) 2.13
Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo. Radiology (2008) 1.88
Molecular imaging in atherosclerosis, thrombosis, and vascular inflammation. Arterioscler Thromb Vasc Biol (2009) 1.65
Quantification and monitoring of inflammation in murine inflammatory bowel disease with targeted contrast-enhanced US. Radiology (2011) 1.64
Improving sensitivity in ultrasound molecular imaging by tailoring contrast agent size distribution: in vivo studies. Mol Imaging (2010) 1.63
Microbubble ultrasound contrast agents: an update. Eur Radiol (2007) 1.57
Molecular ultrasound imaging: current status and future directions. Clin Radiol (2010) 1.51
Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides. J Nucl Med (2010) 1.50
Effect of microbubble size on fundamental mode high frequency ultrasound imaging in mice. Ultrasound Med Biol (2010) 1.40
Early assessment of pulmonary inflammation by 19F MRI in vivo. Circ Cardiovasc Imaging (2010) 1.22
Cavitation threshold of microbubbles in gel tunnels by focused ultrasound. Ultrasound Med Biol (2007) 1.18
Earlier detection of breast cancer with ultrasound molecular imaging in a transgenic mouse model. Cancer Res (2013) 1.12
Assessment of molecular imaging of angiogenesis with three-dimensional ultrasonography. Mol Imaging (2011) 1.11
Targeted delivery of therapeutics to endothelium. Cell Tissue Res (2008) 1.10
An approach to molecular imaging of atherosclerosis, thrombosis, and vascular inflammation using microparticles of iron oxide. Atherosclerosis (2009) 1.08
Multimodality imaging of myocardial injury and remodeling. J Nucl Med (2010) 1.08
Molecular imaging of cardiovascular disease with contrast-enhanced ultrasonography. Nat Rev Cardiol (2009) 1.08
Molecular imaging of cardiovascular disease using ultrasound. J Nucl Cardiol (2008) 1.06
Molecular imaging of disease with targeted contrast ultrasound imaging. Transl Res (2012) 1.02
Molecular imaging with targeted perfluorocarbon nanoparticles: quantification of the concentration dependence of contrast enhancement for binding to sparse cellular epitopes. Ultrasound Med Biol (2007) 1.00
Real time monitoring of biomaterial-mediated inflammatory responses via macrophage-targeting NIR nanoprobes. Biomaterials (2011) 0.98
Contrast ultrasound molecular imaging of inflammation in cardiovascular disease. Cardiovasc Res (2009) 0.98
Vascular endothelial growth factor receptor type 2-targeted contrast-enhanced US of pancreatic cancer neovasculature in a genetically engineered mouse model: potential for earlier detection. Radiology (2014) 0.95
Imaging myocardial metabolic remodeling. J Nucl Med (2010) 0.91
Photoacoustic and ultrasound imaging using dual contrast perfluorocarbon nanodroplets triggered by laser pulses at 1064 nm. Biomed Opt Express (2014) 0.88
Targeted renal therapies through microbubbles and ultrasound. Adv Drug Deliv Rev (2010) 0.87
Binding dynamics of targeted microbubbles in response to modulated acoustic radiation force. Phys Med Biol (2013) 0.86
Plaque hemorrhage in carotid artery disease: pathogenesis, clinical and biomechanical considerations. J Biomech (2014) 0.85
Leveraging the power of ultrasound for therapeutic design and optimization. J Control Release (2011) 0.85
Toward ultrasound molecular imaging with phase-change contrast agents: an in vitro proof of principle. Ultrasound Med Biol (2013) 0.85
Effect of acoustic power on in vivo molecular imaging with targeted microbubbles: implications for low-mechanical index real-time imaging. J Am Soc Echocardiogr (2009) 0.85
Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery. Front Pharmacol (2015) 0.85
Nanoparticle delivery enhancement with acoustically activated microbubbles. IEEE Trans Ultrason Ferroelectr Freq Control (2013) 0.84
Will molecular optical imaging have clinically important roles in stroke management, and how? J Clin Neurol (2010) 0.84
Creating brain lesions with low-intensity focused ultrasound with microbubbles: a rat study at half a megahertz. Ultrasound Med Biol (2013) 0.83
Ultrasound imaging of oxidative stress in vivo with chemically-generated gas microbubbles. Ann Biomed Eng (2012) 0.83
Renal retention of lipid microbubbles: a potential mechanism for flank discomfort during ultrasound contrast administration. J Am Soc Echocardiogr (2013) 0.81
Optical Verification of Microbubble Response to Acoustic Radiation Force in Large Vessels With In Vivo Results. Invest Radiol (2015) 0.81
Ultrasound-based measurement of molecular marker concentration in large blood vessels: a feasibility study. Ultrasound Med Biol (2014) 0.80
In vivo imaging approaches in animal models of rheumatoid arthritis. Arthritis Res Ther (2003) 0.80
Ultrasound imaging for risk assessment in atherosclerosis. Int J Mol Sci (2015) 0.79
Direct Thrombus Imaging in Stroke. J Stroke (2016) 0.78
Albumin-based microbubbles bind up-regulated scavenger receptors following vascular injury. J Biol Chem (2010) 0.78
Preparation of human hepatocellular carcinoma-targeted liposome microbubbles and their immunological properties. World J Gastroenterol (2004) 0.78
Doxorubicin nanobubble for combining ultrasonography and targeted chemotherapy of rabbit with VX2 liver tumor. Tumour Biol (2016) 0.78
Microbubbles and ultrasound: a bird's eye view. Trans Am Clin Climatol Assoc (2004) 0.78
Ultrasound contrast materials in cardiovascular medicine: from perfusion assessment to molecular imaging. J Cardiovasc Transl Res (2013) 0.77
Cardiovascular molecular imaging with contrast ultrasound: principles and applications. Korean Circ J (2014) 0.77
Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. BMC Med Imaging (2013) 0.77
"Eat me" imaging and therapy. Adv Drug Deliv Rev (2016) 0.77
Ultrasound in Radiology: From Anatomic, Functional, Molecular Imaging to Drug Delivery and Image-Guided Therapy. Invest Radiol (2015) 0.77
Local drug and gene delivery through microbubbles and ultrasound. Neth Heart J (2004) 0.76
Kidney-specific Sonoporation-mediated Gene Transfer. Mol Ther (2015) 0.75
Novel ways to noninvasively detect inflammation of the myocardium: contrast-enhanced MRI and myocardial contrast echocardiography. Neth Heart J (2003) 0.75
In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications. Biomicrofluidics (2016) 0.75
Effects of Cationic Microbubble Carrying CD/TK Double Suicide Gene and αVβ3 Integrin Antibody in Human Hepatocellular Carcinoma HepG2 Cells. PLoS One (2016) 0.75
Ultrasound detection of myocardial ischemic memory using an e-selectin targeting Peptide amenable to human application. Mol Imaging (2014) 0.75
Molecular Imaging of Acute Cardiac Transplant Rejection: Animal Experiments and Prospects. Transplantation (2017) 0.75
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Nature (1999) 8.04
The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA (2001) 7.15
Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science (1999) 7.13
Evaluation of chest pain in the emergency department. Ann Intern Med (1994) 7.12
Guided medication dosing for inpatients with renal insufficiency. JAMA (2001) 6.25
Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells. J Virol (1993) 6.11
Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation (1998) 5.93
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc Natl Acad Sci U S A (1997) 5.54
Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity (1994) 5.06
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature (2000) 4.92
Golgi dispersal during microtubule disruption: regeneration of Golgi stacks at peripheral endoplasmic reticulum exit sites. Mol Biol Cell (1996) 4.37
HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase. Cell (1995) 4.25
Genetic definition and sequence analysis of Arabidopsis centromeres. Science (1999) 4.20
Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol. J Natl Cancer Inst (2001) 3.88
RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium. Circulation (2001) 3.86
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res (2000) 3.70
Air quality and pediatric emergency room visits for asthma in Atlanta, Georgia, USA. Am J Epidemiol (2000) 3.37
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E) J Cell Biol (1997) 3.24
Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation (2001) 3.15
Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature (1996) 3.11
Assessment of right ventricular function using two-dimensional echocardiography. Am Heart J (1984) 3.09
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity (2001) 3.08
Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J Exp Med (1996) 3.04
An association between collateral blood flow and myocardial viability in patients with recent myocardial infarction. N Engl J Med (1992) 2.81
Spontaneous skin ulceration and defective T cell function in CD18 null mice. J Exp Med (1998) 2.81
Localization of endoplasmic reticulum in living and glutaraldehyde-fixed cells with fluorescent dyes. Cell (1984) 2.73
Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation (2001) 2.70
Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient mice. Circ Res (1999) 2.60
Distinct phenotype of E-selectin-deficient mice. E-selectin is required for slow leukocyte rolling in vivo. Circ Res (1996) 2.55
Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status. J Natl Cancer Inst (1996) 2.51
Meiosis-specific double-strand DNA breaks at the HIS4 recombination hot spot in the yeast Saccharomyces cerevisiae: control in cis and trans. Mol Cell Biol (1995) 2.49
Disinfection methods in general practice and health authority clinics: a telephone survey. J R Coll Gen Pract (1988) 2.41
Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue. Circulation (1998) 2.37
ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association. J Am Coll Cardiol (1999) 2.37
Local and nonlocal curvature elasticity in bilayer membranes by tether formation from lecithin vesicles. Biophys J (1992) 2.34
Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound. Circulation (1998) 2.30
Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo. J Clin Invest (1998) 2.28
The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis. Osteoarthritis Cartilage (2006) 2.27
The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium. J Clin Invest (2001) 2.26
Changing sex ratio in the United States, 1969-1995. Fertil Steril (1998) 2.23
The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. Cell Death Differ (2005) 2.22
Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol Cell Biol (1996) 2.20
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Nature (2000) 2.17
Tetraspanin CD151 plays a key role in skin squamous cell carcinoma. Oncogene (2012) 2.16
Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice. Blood (2001) 2.11
American College of Cardiology/Society for Cardiac Angiography and Interventions Clinical Expert Consensus Document on cardiac catheterization laboratory standards. A report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol (2001) 2.09
Retrograde transport of Golgi-localized proteins to the ER. J Cell Biol (1998) 2.08
The 18-month impact of an emergency room intervention for adolescent female suicide attempters. J Consult Clin Psychol (2000) 2.05
Delayed onset of inflammation in protease-activated receptor-2-deficient mice. J Immunol (2000) 2.03
Toward cataloguing all rice genes: large-scale sequencing of randomly chosen rice cDNAs from a callus cDNA library. Plant J (1994) 2.02
L-selectin: mechanisms and physiological significance of ectodomain cleavage. J Cell Mol Med (2005) 2.02
Leukocyte rolling in vivo is mediated by P-selectin glycoprotein ligand-1. Blood (1995) 2.01
NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas. Proc Natl Acad Sci U S A (1999) 2.00
Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae. Mol Cell Biol (1995) 1.99
CD24 mediates rolling of breast carcinoma cells on P-selectin. FASEB J (1998) 1.95
Role of beta7 integrins in intestinal lymphocyte homing and retention. Curr Mol Med (2009) 1.94
Pharmacokinetics of stavudine in patients with AIDS or AIDS-related complex. J Infect Dis (1992) 1.94
Purification, characterization, molecular cloning, and expression of two laccase genes from the white rot basidiomycete Trametes villosa. Appl Environ Microbiol (1996) 1.93
How do selectins mediate leukocyte rolling in venules? Biophys J (1992) 1.92
Overregularization in language acquisition. Monogr Soc Res Child Dev (1992) 1.92
Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340. J Biol Chem (2000) 1.89
Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron (1997) 1.89
Use of sildenafil (Viagra) in patients with cardiovascular disease. Technology and Practice Executive Committee. Circulation (1999) 1.87
Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Nature (2000) 1.85
Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1. J Exp Med (1996) 1.85
End-of-life decision making: when patients and surrogates disagree. J Clin Ethics (1999) 1.83
Optical and acoustical observations of the effects of ultrasound on contrast agents. IEEE Trans Ultrason Ferroelectr Freq Control (1999) 1.82
p-Nitrophenylcarbonyl-PEG-PE-liposomes: fast and simple attachment of specific ligands, including monoclonal antibodies, to distal ends of PEG chains via p-nitrophenylcarbonyl groups. Biochim Biophys Acta (2001) 1.82
Retrotransposon-related DNA sequences in the centromeres of grass chromosomes. Genetics (1998) 1.80
Physiologic hyperinsulinemia enhances human skeletal muscle perfusion by capillary recruitment. Diabetes (2001) 1.80
Microvascular integrity indicates myocellular viability in patients with recent myocardial infarction. New insights using myocardial contrast echocardiography. Circulation (1994) 1.79
Quantification of renal blood flow with contrast-enhanced ultrasound. J Am Coll Cardiol (2001) 1.77
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. Cell Death Differ (2006) 1.77
Contrast echocardiography: current and future applications. J Am Soc Echocardiogr (2000) 1.76
Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action. Diabetes (2001) 1.74
An outbreak of syphilis in Alabama prisons: correctional health policy and communicable disease control. Am J Public Health (2001) 1.73
Role of vascular cell adhesion molecule-1 and fibronectin connecting segment-1 in monocyte rolling and adhesion on early atherosclerotic lesions. Circ Res (2000) 1.71
Inter- and intrapatient variability in etoposide kinetics with oral and intravenous drug administration. Clin Cancer Res (1999) 1.70
Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice. Gastroenterology (2001) 1.69
American College of Cardiology/American Heart Association Expert Consensus document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease. Circulation (2000) 1.69
L-selectin shedding regulates leukocyte recruitment. J Exp Med (2001) 1.68
Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. J Exp Med (1993) 1.68
Post-ischaemic myocardial dysfunction (stunning) results from myofibrillar oedema. Heart (2007) 1.67
Indexing and the object concept: developing `what' and `where' systems. Trends Cogn Sci (1998) 1.67
Arthritis prevalence and activity limitations in older adults. Arthritis Rheum (2001) 1.65
Red cell distribution at microvascular bifurcations. Microvasc Res (1989) 1.64
Immunogenicity of peptides derived from a fibronectin-binding protein of S. aureus expressed on two different plant viruses. Vaccine (1999) 1.63
Meningococcal disease in Wales: clinical features, outcome and public health management. J Infect (1992) 1.60
Sarcoglycanopathies: a clinico-pathological study. Neurol India (2007) 1.59
The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo. Development (1999) 1.59
Adhesion molecules and atherogenesis. Acta Physiol Scand (2001) 1.58
Toward high-throughput genotyping: dynamic and automatic software for manipulating large-scale genotype data using fluorescently labeled dinucleotide markers. Genome Res (2001) 1.58
Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media Mol Imaging (2006) 1.58