Published in N Engl J Med on August 03, 2000
Statin use and risk of prostate cancer: results from a population-based epidemiologic study. Am J Epidemiol (2008) 2.79
A pravastatin dose-escalation study in systemic lupus erythematosus. Rheumatol Int (2007) 1.54
MicroRNA in ischemic stroke etiology and pathology. Physiol Genomics (2010) 1.48
Lipid levels and the risk of ischemic stroke in women. Neurology (2007) 1.23
Statins, risk of dementia, and cognitive function: secondary analysis of the ginkgo evaluation of memory study. J Stroke Cerebrovasc Dis (2011) 1.12
Statin therapy is associated with improved patency of autogenous infrainguinal bypass grafts. J Vasc Surg (2004) 1.03
Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis. Eur Heart J (2012) 0.91
The association between serum adhesion molecules and outcome in acute spontaneous intracerebral hemorrhage. Crit Care (2011) 0.83
The incidence of hemorrhagic stroke in Japan is twice compared with western countries: the Akita stroke registry. Neurol Sci (2014) 0.82
Statins for the prevention of stroke: a meta-analysis of randomized controlled trials. PLoS One (2014) 0.82
The Japan Statin Treatment Against Recurrent Stroke (J-STARS): A Multicenter, Randomized, Open-label, Parallel-group Study. EBioMedicine (2015) 0.82
Possible modification of Alzheimer's disease by statins in midlife: interactions with genetic and non-genetic risk factors. Front Aging Neurosci (2014) 0.80
Clinical neuroprotective drugs for treatment and prevention of stroke. Int J Mol Sci (2012) 0.79
Evolving Treatment Strategies for Carotid Artery Stenosis. Curr Treat Options Cardiovasc Med (2004) 0.78
Characteristics of subjects with very low serum low-density lipoprotein cholesterol and the risk for intracerebral hemorrhage. Korean J Intern Med (2012) 0.78
Lipid management in the prevention of stroke: a meta-analysis of fibrates for stroke prevention. BMC Neurol (2013) 0.78
Low total cholesterol level is the independent predictor of poor outcomes in patients with acute ischemic stroke: a hospital-based prospective study. BMC Neurol (2016) 0.78
Rationale, design, and baseline features of a randomized controlled trial to assess the effects of statin for the secondary prevention of stroke: the Japan Statin Treatment Against Recurrent Stroke (J-STARS). Int J Stroke (2013) 0.78
Antithrombotic Secondary Prevention After Stroke. Curr Treat Options Cardiovasc Med (2002) 0.77
The many roles of statins in ischemic stroke. Curr Neuropharmacol (2014) 0.77
Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly. Clin Interv Aging (2010) 0.77
Recent Advances in Stem Cell-Based Therapeutics for Stroke. Transl Stroke Res (2016) 0.76
Can we use statins to prevent stroke in Fabry disease? J Inherit Metab Dis (2009) 0.76
Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke. Int J Mol Sci (2016) 0.75
The Japan Statin Treatment Against Recurrent Stroke (J-STARS) Trial: Where to Now? EBioMedicine (2015) 0.75
Pravastatin therapy and the risk of stroke. N Engl J Med (2000) 0.75
All cholesterol-lowering interventions are expected to reduce stroke: Confirmatory data from IMPROVE-IT. Data Brief (2016) 0.75
Pravastatin therapy and the risk of stroke. N Engl J Med (2000) 0.75
Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet (1990) 24.72
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet (2005) 13.18
Publication bias: the case for an international registry of clinical trials. J Clin Oncol (1986) 12.14
Publication bias: evidence of delayed publication in a cohort study of clinical research projects. BMJ (1997) 9.69
A structure for deoxyribose nucleic acid. 1953. Nature (2003) 9.42
Origin of concatemeric T7 DNA. Nat New Biol (1972) 9.08
Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet (2000) 8.46
Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ (2000) 7.36
Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial. Lancet (2007) 6.82
Automated image registration: II. Intersubject validation of linear and nonlinear models. J Comput Assist Tomogr (1998) 6.75
Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke (2001) 6.32
A direct demonstration of functional specialization in human visual cortex. J Neurosci (1991) 5.71
Screening for colorectal cancer using the faecal occult blood test, Hemoccult. Cochrane Database Syst Rev (2007) 5.63
Serum cholesterol concentration and coronary heart disease in population with low cholesterol concentrations. BMJ (1991) 5.45
Are antibiotics indicated as initial treatment for children with acute otitis media? A meta-analysis. BMJ (1997) 5.26
Self-monitoring of oral anticoagulation: a systematic review and meta-analysis. Lancet (2006) 5.11
A systematic review of the effects of screening for colorectal cancer using the faecal occult blood test, hemoccult. BMJ (1998) 4.44
Management of raised blood pressure in New Zealand: a discussion document. BMJ (1993) 3.96
Bed rest: a potentially harmful treatment needing more careful evaluation. Lancet (1999) 3.80
Blood pressure and cardiovascular disease in the Asia Pacific region. J Hypertens (2003) 3.67
Swallowing function after stroke: prognosis and prognostic factors at 6 months. Stroke (1999) 3.57
Randomised comparison of procedures for obtaining informed consent in clinical trials of treatment for cancer. Br Med J (Clin Res Ed) (1986) 3.52
Comparison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review. JAMA (1997) 3.51
The Internet and evidence-based decision-making: a needed synergy for efficient knowledge management in health care. CMAJ (2000) 3.46
Letter: Potential biohazards of recombinant DNA molecules. Science (1974) 3.45
Nonparametric analysis of statistic images from functional mapping experiments. J Cereb Blood Flow Metab (1996) 3.44
Meta-analytic methods for diagnostic test accuracy. J Clin Epidemiol (1995) 3.38
Reliable assessment of the effects of treatment on mortality and major morbidity, I: clinical trials. Lancet (2001) 3.32
Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry. Circulation (2000) 3.12
Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease. Br Med Bull (1994) 3.09
Effect of calcium supplementation on pregnancy-induced hypertension and preeclampsia: a meta-analysis of randomized controlled trials. JAMA (1996) 2.98
Accident and emergency attendance rates: variation among patients from different general practices. Br J Gen Pract (1990) 2.91
Clinical effects of anticoagulant therapy in suspected acute myocardial infarction: systematic overview of randomised trials. BMJ (1996) 2.90
Evidence-based disease management. JAMA (1997) 2.85
Effect of intravenous nitrates on mortality in acute myocardial infarction: an overview of the randomised trials. Lancet (1988) 2.84
Systematic reviews of chemotherapy and endocrine therapy in metastatic breast cancer. Cancer Treat Rev (2000) 2.78
1999 World Health Organization-International Society of Hypertension Guidelines for the management of hypertension. Guidelines sub-committee of the World Health Organization. Clin Exp Hypertens (1999) 2.72
Chronic heart failure in Australian general practice. The Cardiac Awareness Survey and Evaluation (CASE) Study. Med J Aust (2001) 2.71
Streptokinase for acute ischemic stroke with relationship to time of administration: Australian Streptokinase (ASK) Trial Study Group. JAMA (1996) 2.67
Prevalence of diabetes and impaired glucose tolerance in the biracial (Melanesian and Indian) population of Fiji: a rural-urban comparison. Am J Epidemiol (1983) 2.60
Costs and benefits of adjuvant therapy in breast cancer: a quality-adjusted survival analysis. J Clin Oncol (1989) 2.57
Cholesterol, coronary heart disease, and stroke in the Asia Pacific region. Int J Epidemiol (2003) 2.57
Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel. J Intern Med (2006) 2.55
Unbiased stereological estimation of the total number of synapses in a brain region. J Neurocytol (1996) 2.52
Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. Lancet (1995) 2.52
Clinical characteristics and outcome of patients with early (<2 h), intermediate (2-4 h) and late (>4 h) presentation treated by primary coronary angioplasty or thrombolytic therapy for acute myocardial infarction. Eur Heart J (2002) 2.49
How effective are treatments other than antibiotics for acute sore throat? Br J Gen Pract (2000) 2.45
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
The dilemma of the incapacitated patient who has previously refused consent for surgery. BMJ (1997) 2.43
Do men and women respond differently to blood pressure-lowering treatment? Results of prospectively designed overviews of randomized trials. Eur Heart J (2008) 2.41
The effects of diabetes on the risks of major cardiovascular diseases and death in the Asia-Pacific region. Diabetes Care (2003) 2.36
Estimating an individual's true cholesterol level and response to intervention. JAMA (1991) 2.34
Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia (2011) 2.28
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. Proc Natl Acad Sci U S A (1996) 2.24
Diagnostic strategies used in primary care. BMJ (2009) 2.23
Application of the Poincaré plot to heart rate variability: a new measure of functional status in heart failure. Aust N Z J Med (1995) 2.21
Optimal insulin regimens in type 2 diabetes mellitus: systematic review and meta-analyses. Diabetologia (2009) 2.16
The 1993 guidelines for the management of mild hypertension: memorandum from a WHO/ISH meeting. Blood Press (1993) 2.03
Comparison of idrabiotaparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: the Borealis-Atrial Fibrillation Study. J Thromb Haemost (2014) 2.03
One-year results from the Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries (GUSTO-I) trial. GUSTO-I Investigators. Circulation (1996) 2.03
Herpes simplex encephalitis treated with acyclovir: diagnosis and long term outcome. J Neurol Neurosurg Psychiatry (1997) 2.02
Molecular structure of nucleic acids. A structure for deoxyribose nucleic acid. 1953. Ann Intern Med (2003) 2.02
Blood pressure-dependent and independent effects of agents that inhibit the renin-angiotensin system. J Hypertens (2007) 2.01
Trials of streptokinase in severe acute ischaemic stroke. Lancet (1995) 1.98
Medically refractory neurosarcoidosis treated with infliximab. Intern Med J (2011) 1.96
Users' guides to the medical literature: XVII. How to use guidelines and recommendations about screening. Evidence-Based Medicine Working Group. JAMA (1999) 1.96
SOME RELATIONS BETWEEN DNA AND RNA. Proc Natl Acad Sci U S A (1954) 1.92
Does this patient have deep vein thrombosis? JAMA (1998) 1.90
Ethics of n-of-1 trials. Lancet (1995) 1.90
Conscious visual perception without V1. Brain (1993) 1.89
Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study. Diabetologia (2010) 1.88
The use of a specific DNA probe and polymerase chain reaction for the detection of Mycobacterium leprae. J Infect Dis (1990) 1.87
Age and outcome with contemporary thrombolytic therapy. Results from the GUSTO-I trial. Global Utilization of Streptokinase and TPA for Occluded coronary arteries trial. Circulation (1996) 1.87
Continuous relationships between non-diabetic hyperglycaemia and both cardiovascular disease and all-cause mortality: the Australian Diabetes, Obesity, and Lifestyle (AusDiab) study. Diabetologia (2009) 1.85
Validity of self-reported cardiovascular disease events in comparison to medical record adjudication and a statewide hospital morbidity database: the AusDiab study. Intern Med J (2009) 1.81
Tonsillectomy versus non-surgical treatment for chronic / recurrent acute tonsillitis. Cochrane Database Syst Rev (2000) 1.81
Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand Heart Failure Research Collaborative Group. J Am Coll Cardiol (1997) 1.79
Histopathology and fibrillin-1 distribution in severe early onset Marfan syndrome. Am J Med Genet A (2005) 1.77
A comparison of slow release with conventional oxprenolol: plasma concentrations and clinical effects. Br J Clin Pharmacol (1976) 1.76
Atrial fibrillation after coronary artery bypass grafting is associated with sympathetic activation. Ann Thorac Surg (1995) 1.75
The Transfer of Radioactive Phosphorus From Parental to Progeny Phage. Proc Natl Acad Sci U S A (1951) 1.73
Foundress associations in polistine wasps: dominance hierarchies and the evolution of social behavior. Science (1967) 1.73
Necrotising fasciitis. BMJ (1994) 1.72
Nucleotide sequence of the 19 kDa antigen gene from Mycobacterium tuberculosis. Nucleic Acids Res (1989) 1.70
A comparison of the associations between seven hemostatic or inflammatory variables and coronary heart disease. J Thromb Haemost (2007) 1.69
Prevalence and correlates of heavy smoking in Vietnam veterans with chronic posttraumatic stress disorder. Addict Behav (1998) 1.68
Antigenic proteins of Mycobacterium leprae. Complete sequence of the gene for the 18-kDa protein. J Immunol (1988) 1.67
Tibio-femoral movement in the living knee. A study of weight bearing and non-weight bearing knee kinematics using 'interventional' MRI. J Biomech (2005) 1.66
Passive ventricular constraint amends the course of heart failure: a study in an ovine model of dilated cardiomyopathy. Cardiovasc Res (1999) 1.65