B cell epitopes of gliadin.

PubWeight™: 1.20‹?› | Rank: Top 10%

🔗 View Article (PMC 1905697)

Published in Clin Exp Immunol on August 01, 2000

Authors

A A Osman1, T Günnel, A Dietl, H H Uhlig, M Amin, B Fleckenstein, T Richter, T Mothes

Author Affiliations

1: Deparment of Clinical Chemistry, University Hospital, Leipzig, and Institute of Organic Chemistry of the University, Tübingen, Germany.

Articles citing this

Persistence of elevated deamidated gliadin peptide antibodies on a gluten-free diet indicates nonresponsive coeliac disease. Aliment Pharmacol Ther (2014) 2.67

Triggers and drivers of autoimmunity: lessons from coeliac disease. Nat Rev Immunol (2013) 1.53

Comparative usefulness of deamidated gliadin antibodies in the diagnosis of celiac disease. Clin Gastroenterol Hepatol (2008) 1.23

Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders. Curr Opin Immunol (2011) 1.13

Usefulness of antibodies to deamidated gliadin peptides in celiac disease diagnosis and follow-up. Dig Dis Sci (2008) 1.08

Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease. Gut (2005) 0.98

The adaptive immune response in celiac disease. Semin Immunopathol (2012) 0.97

Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes. Proc Natl Acad Sci U S A (2013) 0.92

Antibody responses to deamidated gliadin peptide show high specificity and parallel antibodies to tissue transglutaminase in developing coeliac disease. Clin Exp Immunol (2007) 0.88

Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells. Nat Commun (2014) 0.86

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens. Nat Rev Rheumatol (2015) 0.83

Children with celiac disease and high tTGA are genetically and phenotypically different. World J Gastroenterol (2013) 0.82

IgA antibodies of coeliac disease patients recognise a dominant T cell epitope of A-gliadin. Gut (2004) 0.80

Detection of specific IgA antibodies against a novel deamidated 8-Mer gliadin peptide in blood plasma samples from celiac patients. PLoS One (2013) 0.79

Identification of disease-specific motifs in the antibody specificity repertoire via next-generation sequencing. Sci Rep (2016) 0.79

Immunoreactivity of antibodies against transglutaminase-deamidated gliadins in adult celiac disease. Dig Dis Sci (2008) 0.77

Usefulness of recombinant γ-gliadin 1 for identifying patients with celiac disease and monitoring adherence to a gluten-free diet. J Allergy Clin Immunol (2015) 0.77

Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes. Sci Rep (2016) 0.76

Determination of B-Cell Epitopes in Patients with Celiac Disease: Peptide Microarrays. PLoS One (2016) 0.75

Characterization of globulin storage proteins of a low prolamin cereal species in relation to celiac disease. Sci Rep (2017) 0.75

Serology of celiac disease in gluten-sensitive ataxia or neuropathy: role of deamidated gliadin antibody. J Neuroimmunol (2010) 0.75

Design of a peptide for immunodetection of IgA antigliadin antibody for the purpose of screening of celiac disease. Bioinformation (2012) 0.75

Coeliac disease: a unique model for investigating broken tolerance in autoimmunity. Clin Transl Immunology (2016) 0.75

Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight (2017) 0.75

The roles of MHC class II genes and post-translational modification in celiac disease. Immunogenetics (2017) 0.75

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. J Biochem Biophys Methods (1984) 11.70

Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med (1997) 7.42

Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Nat Med (1998) 5.25

Coeliac disease. Lancet (1997) 3.26

Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity. J Immunol (1998) 2.88

Evolution and heterogeneity of the alpha-/beta-type and gamma-type gliadin DNA sequences. J Biol Chem (1985) 2.19

Fortnightly review: coeliac disease. BMJ (1999) 2.17

The prolamin storage proteins of cereal seeds: structure and evolution. Biochem J (1990) 2.13

Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin. Proc Natl Acad Sci U S A (1998) 1.99

Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition. Scand J Immunol (1998) 1.85

Nucleic acid (cDNA) and amino acid sequences of alpha-type gliadins from wheat (Triticum aestivum). Proc Natl Acad Sci U S A (1984) 1.83

Synthesis and screening of peptide libraries on continuous cellulose membrane supports. Methods Mol Biol (1998) 1.74

Comparison of IgA-class reticulin and endomysium antibodies in coeliac disease and dermatitis herpetiformis. Gut (1989) 1.65

The pathogenesis of celiac disease. Gastroenterology (1998) 1.63

Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases. J Biol Chem (1991) 1.60

Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease. Gut (1999) 1.54

HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope. Eur J Immunol (1999) 1.38

T cells recognize a peptide derived from alpha-gliadin presented by the celiac disease-associated HLA-DQ (alpha 1*0501, beta 1*0201) heterodimer. Hum Immunol (1994) 1.37

Anti-tissue transglutaminase, anti-endomysium and anti-R1-reticulin autoantibodies-the antibody trinity of coeliac disease. Clin Exp Immunol (1999) 1.04

Epitope mapping by screening of phage display libraries of a monoclonal antibody directed against the receptor binding domain of human alpha2-macroglobulin. FEBS Lett (1997) 0.93

Conformational studies of peptides corresponding to the coeliac-activating regions of wheat alpha-gliadin. Biochem J (1990) 0.90

Studies on the significance of the R1 anti-reticulin antibody associated with gluten sensitivity. Int Arch Allergy Appl Immunol (1985) 0.90

Anti-alpha-gliadin antibodies (AGA) in the serum of coeliac children and controls recognize an identical collection of linear epitopes of alpha-gliadin. Clin Exp Immunol (1998) 0.89

Reaction of human non-collagenous polypeptides with coeliac disease autoantibodies. Lancet (1991) 0.87

Use of the phage display technique for detection of epitopes recognized by polyclonal rabbit gliadin antibodies. FEBS Lett (1998) 0.82

The IgA subclass distributions of endomysium and gliadin antibodies in human sera are different. Clin Chim Acta (1996) 0.81

Increased HLA-DQ2-affinity of a synthetic gliadin peptide by acid-induced deamidation of glutamine residues. Bioorg Med Chem Lett (1998) 0.80

Role of tissue transglutaminase in gliadin binding to reticular extracellular matrix and relation to coeliac disease autoantibodies. Autoimmunity (1998) 0.78

The immunologic basis for celiac disease and related disorders. Semin Gastrointest Dis (1996) 0.78

Articles by these authors

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell (1985) 16.46

Primary structure of the herpesvirus saimiri genome. J Virol (1992) 5.26

Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue. Am J Pathol (2001) 4.18

Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet (2000) 3.92

Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity? J Virol (1997) 3.88

Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer (1997) 3.85

Cloning of the complete human cytomegalovirus genome in cosmids. Gene (1982) 3.55

Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell lines. Proc Natl Acad Sci U S A (1979) 3.24

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53. Proc Natl Acad Sci U S A (1990) 3.20

Predominant immediate-early transcripts of human cytomegalovirus AD 169. J Virol (1984) 3.15

The family Herpesviridae: an update. The Herpesvirus Study Group of the International Committee on Taxonomy of Viruses. Arch Virol (1992) 3.09

Stable growth transformation of human T lymphocytes by herpesvirus saimiri. Proc Natl Acad Sci U S A (1992) 2.94

Sarcomatoid differentiation in renal cell carcinoma: a study of 101 cases. Am J Surg Pathol (2001) 2.91

Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer. Proc Natl Acad Sci U S A (1987) 2.89

Structure of Herpesvirus saimiri genomes: arrangement of heavy and light sequences in the M genome. J Virol (1976) 2.87

Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector. Proc Natl Acad Sci U S A (1989) 2.64

Nuclear factor 1 interacts with five DNA elements in the promoter region of the human cytomegalovirus major immediate early gene. EMBO J (1986) 2.62

Primary structure and transcription of the genes coding for the two virion phosphoproteins pp65 and pp71 of human cytomegalovirus. J Virol (1987) 2.60

Molecular evidence for transmission of hepatitis G virus by blood transfusion. Lancet (1996) 2.57

Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin. J Virol (1997) 2.57

Human herpesvirus 8 encodes a homolog of interleukin-6. J Virol (1997) 2.56

Characterization of monoclonal antibodies and polyclonal immune sera directed against human cytomegalovirus virion proteins. Virology (1984) 2.48

Five- to 7-year-old children with Helicobacter pylori infection are smaller than Helicobacter-negative children: a cross-sectional population-based study of 3,315 children. J Pediatr Gastroenterol Nutr (2001) 2.42

Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus. Nat Med (1998) 2.38

Repetitive sequences in complete and defective genomes of Herpesvirus saimiri. J Virol (1975) 2.36

The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype. Virology (1990) 2.28

Structure of nonintegrated, circular Herpesvirus saimiri and Herpesvirus ateles genomes in tumor cell lines and in vitro-transformed cells. J Virol (1982) 2.23

Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture. J Virol (1992) 2.21

Deletion of DNA sequence in a nononcogenic variant of Herpesvirus saimiri. J Virol (1984) 2.14

The two major structural phosphoproteins (pp65 and pp150) of human cytomegalovirus and their antigenic properties. J Gen Virol (1987) 2.13

Map position and nucleotide sequence of the gene for the large structural phosphoprotein of human cytomegalovirus. J Virol (1987) 2.11

Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins. Nature (1997) 2.10

Herpesvirus saimiri DNA in a lymphoid cell line established by in vitro transformation. J Virol (1984) 2.09

Cell type-specific induction of the major immediate early enhancer of human cytomegalovirus by cyclic AMP. J Gen Virol (1990) 2.06

Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells. Blood (1998) 1.93

Episomal viral DNA in a Herpesvirus saimiri-transformed lymphoid cell line. J Virol (1977) 1.93

Transformation of NIH 3T3 cells with cloned fragments of human cytomegalovirus strain AD169. J Virol (1982) 1.88

Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study. Allergy (2012) 1.88

Physical mapping of human cytomegalovirus genes: identification of DNA sequences coding for a virion phosphoprotein of 71 kDa and a viral 65-kDa polypeptide. Virology (1984) 1.81

Cell surface heparan sulfate is a receptor for human herpesvirus 8 and interacts with envelope glycoprotein K8.1. J Virol (2001) 1.76

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas. Proc Natl Acad Sci U S A (1999) 1.73

Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors. Proc Natl Acad Sci U S A (1995) 1.69

Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene. J Virol (1987) 1.67

Mapping of the major glycoprotein gene of human cytomegalovirus. J Gen Virol (1986) 1.66

The immunogenic glycoprotein gp35-37 of human herpesvirus 8 is encoded by open reading frame K8.1. J Virol (1998) 1.66

The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells. J Biol Chem (1995) 1.65

Complications of whole bladder dihematoporphyrin ether photodynamic therapy. J Urol (1989) 1.62

Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor. J Virol (1998) 1.62

Gene expression profiling of human stent-induced neointima by cDNA array analysis of microscopic specimens retrieved by helix cutter atherectomy: Detection of FK506-binding protein 12 upregulation. Circulation (2001) 1.61

Purification and properties of Herpesvirus saimiri DNA. Virology (1974) 1.55

Primary structure of the alcelaphine herpesvirus 1 genome. J Virol (1997) 1.55

Patient mobile telephone 'text' reminder: a novel way to reduce non-attendance at the ENT out-patient clinic. J Laryngol Otol (2007) 1.53

Hereditary papillary renal cell carcinoma: clinical studies in 10 families. J Urol (1995) 1.53

Herpesvirus ateles DNA and its homology with Herpesvirus saimiri nucleic acid. J Virol (1978) 1.53

Terminal repetitive sequences in herpesvirus saimiri virion DNA. J Virol (1985) 1.51

The A+T-rich genome of Herpesvirus saimiri contains a highly conserved gene for thymidylate synthase. Proc Natl Acad Sci U S A (1986) 1.51

Infundibulopelvic dysgenesis: a spectrum of obstructive renal disease. Urology (1990) 1.48

Discordant expression of the immediate-early 1 and 2 gene regions of human cytomegalovirus at early times after infection involves posttranscriptional processing events. J Virol (1991) 1.48

Wild type human p53 is antiproliferative in SV40-transformed hamster cells. Oncogene (1990) 1.47

Sertraline safety and efficacy in major depression: a double-blind fixed-dose comparison with placebo. Biol Psychiatry (1995) 1.46

Oncogenic herpesviruses of non-human primates. Biochim Biophys Acta (1979) 1.44

In vitro binding of human T-cell leukemia virus rex proteins to the rex-response element of viral transcripts. J Virol (1991) 1.44

The presence of Herpesvirus Saimiri genomes in virus-transformed cells. Int J Cancer (1977) 1.43

Cloning of Herpesvirus saimiri DNA fragments representing the entire L-region of the genome. Gene (1983) 1.41

The role of a repetitive palindromic sequence element in the human cytomegalovirus major immediate early enhancer. J Gen Virol (1989) 1.39

Structural organization of the conserved gene block of Herpesvirus saimiri coding for DNA polymerase, glycoprotein B, and major DNA binding protein. Virology (1990) 1.38

Severe anxiety induced by FG 7142, a beta-carboline ligand for benzodiazepine receptors. Lancet (1983) 1.38

Dose equivalent for haloperidol and phenothiazines. Can Med Assoc J (1967) 1.38

Identification and biochemical characterization of Arabidopsis thaliana sulfite oxidase. A new player in plant sulfur metabolism. J Biol Chem (2001) 1.38

ON GUAIACOL SOLUTIONS : I. THE ELECTRICAL CONDUCTIVITY OF SODIUM AND POTASSIUM GUAIACOLATES IN GUAIACOL. J Gen Physiol (1934) 1.37

Structure of the transforming region of human cytomegalovirus AD169. J Virol (1984) 1.35

CASUAL AND BASAL BLOOD PRESSURES III.-IN RENAL HYPERTENSION. Br Heart J (1943) 1.35

The 160,000-Mr virion protein encoded at the right end of the herpesvirus saimiri genome is homologous to the 140,000-Mr membrane antigen encoded at the left end of the Epstein-Barr virus genome. J Virol (1987) 1.33

Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59. Virology (1992) 1.32

Genome structure and virion polypeptides of the primate herpesviruses Herpesvirus aotus types 1 and 3: comparison with human cytomegalovirus. J Virol (1983) 1.32

Virus-specific transcription in a Herpesvirus saimiri-transformed lymphoid tumor cell line. J Virol (1983) 1.31

New member of the multigene family of complement control proteins in herpesvirus saimiri. J Virol (1992) 1.31

Radical neck dissection: a 19-year experience. J Laryngol Otol (1989) 1.28

Human cytomegalovirus DNA sequences with homologies to the cellular genome. J Gen Virol (1984) 1.27

Graduate medical education, 1998-1999: a closer look. JAMA (1999) 1.27

Endogenous New World primate type C viruses isolated from owl monkey (Aotus trivirgatus) kidney cell line. Proc Natl Acad Sci U S A (1978) 1.26

Susceptibility to Herpesvirus saimiri and antibody development in old and new world monkeys. Med Microbiol Immunol (1973) 1.26

Ultrastructural observations on mitochondria and microvesicles in renal oncocytoma, chromophobe renal cell carcinoma, and eosinophilic variant of conventional (clear cell) renal cell carcinoma. Am J Surg Pathol (2000) 1.25

The superantigen-homologous viral immediate-early gene ie14/vsag in herpesvirus saimiri-transformed human T cells. J Virol (1997) 1.24

Herpesvirus saimiri. Philos Trans R Soc Lond B Biol Sci (2001) 1.24

Persistence of selectable herpesvirus saimiri in various human haematopoietic and epithelial cell lines. J Gen Virol (1991) 1.23

Genetic relationships between bovine herpesvirus 4 and the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri. Virology (1992) 1.22

Primary, pure, large-cell neuroendocrine carcinoma of the urinary bladder. Mod Pathol (1998) 1.21

Construction, replication, and immunogenic properties of a simian immunodeficiency virus expressing interleukin-2. J Virol (1997) 1.20

Open pelvic fractures. J Trauma (1982) 1.20

Retromandibular approach to the mandibular condyle: a clinical and cadaveric study. Int J Oral Maxillofac Surg (2003) 1.19

Antioxidants selectively suppress activation of NF-kappa B by human T-cell leukemia virus type I Tax protein. J Virol (1992) 1.18

Some fundamental actions of antiarrhythmic drugs on the excitability and the contractility of singel myocardial fibers. Naunyn Schmiedebergs Arch Pharmakol (1971) 1.18

The complement control protein homolog of herpesvirus saimiri regulates serum complement by inhibiting C3 convertase activity. J Virol (1995) 1.18

The unique region of the human herpesvirus 6 genome is essentially collinear with the UL segment of human cytomegalovirus. J Gen Virol (1991) 1.17

Selectable recombinant herpesvirus saimiri is capable of persisting in a human T-cell line. J Virol (1989) 1.16

Structural proteins of Herpesvirus saimiri. J Virol (1983) 1.15

Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes. J Virol (1996) 1.14

Toxic effects of indocyanine green, infracyanine green, and trypan blue on the human retinal pigmented epithelium. Graefes Arch Clin Exp Ophthalmol (2005) 1.14