Published in J Immunol on September 01, 2000
In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies. Science (2008) 5.09
The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies. Am J Pathol (2005) 1.97
Neutrophil depletion during Toxoplasma gondii infection leads to impaired immunity and lethal systemic pathology. Infect Immun (2001) 1.92
Vector transmission of leishmania abrogates vaccine-induced protective immunity. PLoS Pathog (2009) 1.68
IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice. J Immunol (2009) 1.63
IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani. J Clin Invest (2009) 1.53
Granulocytes impose a tight bottleneck upon the gut luminal pathogen population during Salmonella typhimurium colitis. PLoS Pathog (2014) 1.44
SC83288 is a clinical development candidate for the treatment of severe malaria. Nat Commun (2017) 1.41
Intracellular survival of Leishmania major in neutrophil granulocytes after uptake in the absence of heat-labile serum factors. Infect Immun (2002) 1.39
Intradermal infection model for pathogenesis and vaccine studies of murine visceral leishmaniasis. Infect Immun (2003) 1.38
Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani. Infect Immun (2007) 1.36
Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proc Natl Acad Sci U S A (2009) 1.35
Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response. PLoS Pathog (2012) 1.32
Novel program of macrophage gene expression induced by phagocytosis of Leishmania chagasi. Infect Immun (2004) 1.29
Blockade of individual Notch ligands and receptors controls graft-versus-host disease. J Clin Invest (2013) 1.27
Toward a novel experimental model of infection to study American cutaneous leishmaniasis caused by Leishmania braziliensis. Infect Immun (2005) 1.27
Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences. Cell Mol Life Sci (2013) 1.26
Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice. PLoS Pathog (2010) 1.14
The impact of vector-mediated neutrophil recruitment on cutaneous leishmaniasis. Cell Microbiol (2009) 1.13
Leishmania promastigotes release a granulocyte chemotactic factor and induce interleukin-8 release but inhibit gamma interferon-inducible protein 10 production by neutrophil granulocytes. Infect Immun (2002) 1.11
Treatment of mice with the neutrophil-depleting antibody RB6-8C5 results in early development of experimental lyme arthritis via the recruitment of Gr-1- polymorphonuclear leukocyte-like cells. Infect Immun (2004) 1.10
Elastase release by transmigrating neutrophils deactivates endothelial-bound SDF-1alpha and attenuates subsequent T lymphocyte transendothelial migration. J Exp Med (2004) 1.10
TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS Pathog (2014) 1.10
Leukocytes infiltrate the skin and draining lymph nodes in response to the protozoan Leishmania infantum chagasi. Infect Immun (2010) 1.06
Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites. J Immunol (2010) 1.06
Mechanisms of immune evasion in leishmaniasis. Adv Appl Microbiol (2013) 1.04
In vivo involvement of polymorphonuclear neutrophils in Leishmania infantum infection. BMC Microbiol (2001) 1.03
The prominent role of neutrophils during the initial phase of infection by Leishmania parasites. J Biomed Biotechnol (2009) 1.02
Neutrophils clear bacteria associated with parasitic nematodes augmenting the development of an effective Th2-type response. J Immunol (2008) 1.00
Innate immunity to influenza virus: implications for future therapy. Expert Rev Clin Immunol (2008) 0.99
The influence of early neutrophil-Leishmania interactions on the host immune response to infection. Front Cell Infect Microbiol (2012) 0.99
Does T Helper Differentiation Correlate with Resistance or Susceptibility to Infection with L. major? Some Insights From the Murine Model. Front Immunol (2012) 0.98
Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils. J Infect Dis (2014) 0.95
Murine neutrophils present Class II restricted antigen. Immunol Lett (2008) 0.94
Compartment-specific remodeling of splenic micro-architecture during experimental visceral leishmaniasis. Am J Pathol (2011) 0.92
Transcriptional profiling of the acute pulmonary inflammatory response induced by LPS: role of neutrophils. Respir Res (2010) 0.92
Neutrophils have a protective role during early stages of Leishmania amazonensis infection in BALB/c mice. Parasite Immunol (2014) 0.91
Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin-8, monocyte chemotactic protein-1 and nitric oxide are major regulatory factors. Immunology (2010) 0.91
Neutrophils reduce the parasite burden in Leishmania (Leishmania) amazonensis-infected macrophages. PLoS One (2010) 0.91
Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. PLoS Pathog (2015) 0.89
Cutaneous leishmaniasis: immune responses in protection and pathogenesis. Nat Rev Immunol (2016) 0.88
Accelerated healing of cutaneous leishmaniasis in non-healing BALB/c mice using water soluble amphotericin B-polymethacrylic acid. Biomaterials (2011) 0.87
Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms. Infect Immun (2013) 0.87
Antigen and lipopolysaccharide play synergistic roles in the effector phase of airway inflammation in mice. Am J Pathol (2006) 0.87
The levels and patterns of cytokines produced by CD4 T lymphocytes of BALB/c mice infected with Leishmania major by inoculation into the ear dermis depend on the infectiousness and size of the inoculum. Infect Immun (2003) 0.85
Coinjection with TLR2 agonist Pam3CSK4 reduces the pathology of leishmanization in mice. PLoS Negl Trop Dis (2015) 0.85
What determines the success or failure of intracellular cutaneous parasites? Lessons learned from leishmaniasis. Med Microbiol Immunol (2009) 0.85
Exploring the role of medicinal plant-based immunomodulators for effective therapy of leishmaniasis. Front Immunol (2014) 0.85
Keratinocytes determine Th1 immunity during early experimental leishmaniasis. PLoS Pathog (2010) 0.84
Permissive and protective roles for neutrophils in leishmaniasis. Clin Exp Immunol (2015) 0.84
Experimental infection of immunomodulated NOD/LtSz-SCID mice as a new model for Plasmodium falciparum erythrocytic stages. Parasitol Res (2004) 0.83
Brain immune cell composition and functional outcome after cerebral ischemia: comparison of two mouse strains. Front Cell Neurosci (2014) 0.82
Complement C3 is required for the progression of cutaneous lesions and neutrophil attraction in Leishmania major infection. Med Microbiol Immunol (2004) 0.82
Ex vivo and in vivo biological behavior of Leishmania (Viannia) shawi. Parasitol Res (2009) 0.81
Opposing roles for interferon regulatory factor-3 (IRF-3) and type I interferon signaling during plague. PLoS Pathog (2012) 0.80
Are Neutrophil Extracellular Traps Playing a Role in the Parasite Control in Active American Tegumentary Leishmaniasis Lesions? PLoS One (2015) 0.80
Immunological cells and functions in Gaucher disease. Crit Rev Oncog (2013) 0.80
Imaging of the host/parasite interplay in cutaneous leishmaniasis. Exp Parasitol (2010) 0.80
Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major. PLoS Pathog (2014) 0.79
The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice. Eur J Immunol (2016) 0.79
Neutrophils acquire the capacity for antigen presentation to memory CD4(+) T cells in vitro and ex vivo. Blood (2017) 0.79
Toll-Like Receptor 9 Signaling in Dendritic Cells Regulates Neutrophil Recruitment to Inflammatory Foci following Leishmania infantum Infection. Infect Immun (2015) 0.78
Exposure to Leishmania braziliensis triggers neutrophil activation and apoptosis. PLoS Negl Trop Dis (2015) 0.77
New Insights on the Inflammatory Role of Lutzomyia longipalpis Saliva in Leishmaniasis. J Parasitol Res (2012) 0.77
Impact of neutrophil-secreted myeloid related proteins 8 and 14 (MRP 8/14) on leishmaniasis progression. PLoS Negl Trop Dis (2013) 0.77
Comparative analysis of resistant and susceptible macrophage gene expression response to Leishmania major parasite. BMC Genomics (2013) 0.77
Inhibition of caspase-8 activity promotes protective Th1- and Th2-mediated immunity to Leishmania major infection. J Leukoc Biol (2013) 0.76
Transgenic expression of CXCR3 on T cells enhances susceptibility to cutaneous Leishmania major infection by inhibiting monocyte maturation and promoting a Th2 response. Infect Immun (2014) 0.76
sCD163 levels as a biomarker of disease severity in leprosy and visceral leishmaniasis. PLoS Negl Trop Dis (2017) 0.75
A secondary wave of neutrophil infiltration causes necrosis and ulceration in lesions of experimental American cutaneous leishmaniasis. PLoS One (2017) 0.75
Characterization of Neutrophil Function in Human Cutaneous Leishmaniasis Caused by Leishmania braziliensis. PLoS Negl Trop Dis (2016) 0.75
A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugs. Sci Rep (2016) 0.75
The site of the bite: Leishmania interaction with macrophages, neutrophils and the extracellular matrix in the dermis. Parasit Vectors (2016) 0.75
Painting factor H onto mesenchymal stem cells protects the cells from complement- and neutrophil-mediated damage. Biomaterials (2016) 0.75
Distinct cellular migration induced by Leishmania infantum chagasi and saliva from Lutzomyia longipalpis in a hemorrhagic pool model. Rev Inst Med Trop Sao Paulo (2014) 0.75
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature (2011) 5.41
Malaria pathogenesis. Science (1994) 4.76
A limiting dilution assay for quantifying Leishmania major in tissues of infected mice. Parasite Immunol (1985) 4.71
Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is autoregulated. Mol Microbiol (1991) 3.73
A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity. J Immunol (2000) 3.47
Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice. J Immunol (1985) 3.47
Protection against cutaneous leishmaniasis resulting from bites of uninfected sand flies. Science (2000) 2.92
L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol (1986) 2.79
Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein. J Exp Med (2001) 2.76
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol (1996) 2.76
IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity (1997) 2.54
Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers. Br J Cancer (2006) 2.45
Nucleotide sequence of the first cosmid from the Mycobacterium leprae genome project: structure and function of the Rif-Str regions. Mol Microbiol (1993) 2.45
Exacerbation of murine cutaneous leishmaniasis by adoptive transfer of parasite-specific helper T cell populations capable of mediating Leishmania major-specific delayed-type hypersensitivity. J Immunol (1984) 2.35
Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity. J Exp Med (1998) 2.30
Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science (2014) 2.20
Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response. J Exp Med (1995) 2.17
Effect of plasmodial RESA protein on deformability of human red blood cells harboring Plasmodium falciparum. Proc Natl Acad Sci U S A (2007) 2.14
Importance of L3T4+ and Lyt-2+ cells in the immunologic control of infection with Mycobacterium bovis strain bacillus Calmette-Guérin in mice. Assessment by elimination of T cell subsets in vivo. J Immunol (1987) 2.06
Inhibition of T cell-mediated functions by MVM(i), a parvovirus closely related to minute virus of mice. J Immunol (1981) 1.87
Dendritic cells are early cellular targets of Listeria monocytogenes after intestinal delivery and are involved in bacterial spread in the host. Cell Microbiol (2001) 1.81
Isolation and flow cytometric analysis of the free lymphomyeloid cells present in murine liver. J Immunol Methods (1990) 1.76
IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice. Nat Immunol (2001) 1.73
The potency and durability of DNA- and protein-based vaccines against Leishmania major evaluated using low-dose, intradermal challenge. J Immunol (2001) 1.72
Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains. EMBO J (1994) 1.70
Titration and circulation of cells mediating delayed type hypersensitivity in normal and cyclophosphamide treated mice during response to sheep red blood cells. Immunology (1978) 1.64
Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol (2012) 1.62
Molecular characterisation of ninein, a new coiled-coil protein of the centrosome. J Cell Sci (1996) 1.59
TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction. Eur Cytokine Netw (1994) 1.56
Intracellular destruction of Leishmania tropica by macrophages activated with macrophage activating factor/interferon. Clin Exp Immunol (1984) 1.51
In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-. Eur J Immunol (1995) 1.50
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49
Prevalence and characteristics of meticillin-resistant Staphylococcus aureus in humans in contact with farm animals, in livestock, and in food of animal origin, Switzerland, 2009. Euro Surveill (2010) 1.48
Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis. Eur J Immunol (1987) 1.46
Higher frequency of Leishmania major-specific L3T4+ T cells in susceptible BALB/c as compared with resistant CBA mice. J Immunol (1986) 1.45
Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections. Eur J Immunol (1995) 1.45
Gamma interferon response in secondary Leishmania major infection: role of CD8+ T cells. Infect Immun (1993) 1.43
A role for gamma delta + T cells during experimental infection of mice with Leishmania major. J Immunol (1993) 1.42
The in vitro generation and functional analysis of murine T cell populations and clones specific for a protozoan parasite, Leishmania tropica. Immunol Rev (1982) 1.40
The salivary apyrase of the blood-sucking sand fly Phlebotomus papatasi belongs to the novel Cimex family of apyrases. J Exp Biol (2001) 1.40
Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness. J Immunol (1997) 1.39
Antibody to the murine type 3 complement receptor inhibits T lymphocyte-dependent recruitment of myelomonocytic cells in vivo. J Exp Med (1989) 1.38
Mycobacterial heat-shock proteins as carrier molecules. II: The use of the 70-kDa mycobacterial heat-shock protein as carrier for conjugated vaccines can circumvent the need for adjuvants and Bacillus Calmette Guérin priming. Eur J Immunol (1992) 1.36
Leishmania major-infected murine langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis. Eur J Immunol (2000) 1.36
Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8+ T cells. Int Immunol (1991) 1.35
A role for Lyt-2+ T cells in resistance to cutaneous leishmaniasis in immunized mice. J Immunol (1989) 1.35
Leishmania major interferes with antigen presentation by infected macrophages. J Immunol (1993) 1.35
Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens. J Exp Med (1988) 1.34
Maintenance of granulocyte numbers during acute peritonitis is defective in galectin-3-null mutant mice. Immunology (1998) 1.33
A method to recover, enumerate and identify lymphomyeloid cells present in an inflammatory dermal site: a study in laboratory mice. J Immunol Methods (1996) 1.32
Functional analysis in vitro and in vivo of Mycobacterium bovis strain BCG-specific T cell clones. J Immunol (1986) 1.32
Attenuated Listeria monocytogenes as a live vector for induction of CD8+ T cells in vivo: a study with the nucleoprotein of the lymphocytic choriomeningitis virus. Int Immunol (1995) 1.30
Lysozyme is an inducible marker of macrophage activation in murine tissues as demonstrated by in situ hybridization. J Exp Med (1991) 1.28
Receptors for interleukin-1 (alpha and beta) in mouse brain: mapping and neuronal localization in hippocampus. Neuroscience (1991) 1.26
Increased infiltration by monocytes in delayed type hypersensitivity site following cyclophosphamide treatment. Immunology (1978) 1.26
Exacerbation of experimental murine cutaneous leishmaniasis with CD4+ Leishmania major-specific T cell lines or clones which secrete interferon-gamma and mediate parasite-specific delayed-type hypersensitivity. Eur J Immunol (1991) 1.25
Local adoptive transfer of skin delayed-type hypersensitivity initiated by a single T lymphocyte. J Immunol (1982) 1.25
In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. J Immunol (2000) 1.21
Mycobacterial heat-shock proteins as carrier molecules. Eur J Immunol (1991) 1.21
Dynamics of lymphocytes and inflammatory cells recruited in liver during murine listeriosis. A cytofluorimetric study. J Immunol (1991) 1.21
Immunization of BALB/c mice with Helicobacter urease B induces a T helper 2 response absent in Helicobacter infection. Gastroenterology (1998) 1.20
L3T4+ T cells able to mediate parasite-specific delayed-type hypersensitivity play a role in the pathology of experimental Chagas' disease. Eur J Immunol (1987) 1.20
Distinct innate and acquired immune responses to Leishmania in putative susceptible and resistant human populations endemically exposed to L. (Viannia) panamensis infection. Scand J Immunol (2000) 1.19
Expansion of gamma interferon-producing CD8+ T cells following secondary infection of mice immune to Leishmania major. Infect Immun (1994) 1.19
T-cell lineages, repertoire selection and tolerance induction. Immunol Rev (1988) 1.17
Immunology of leishmaniasis. Curr Opin Immunol (1992) 1.17
Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope. J Exp Med (1999) 1.17
Induction of protective CD8+ T lymphocytes by an attenuated Listeria monocytogenes actA mutant. Int Immunol (1992) 1.15
Immune responses to defined epitopes of the circumsporozoite protein of the murine malaria parasite, Plasmodium yoelii. Eur J Immunol (1990) 1.12
Leishmania major reaches distant cutaneous sites where it persists transiently while persisting durably in the primary dermal site and its draining lymph node: a study with laboratory mice. Infect Immun (2000) 1.12
Immunity to experimental infection with Leishmania major: generation of protective L3T4+ T cell clones recognizing antigen(s) associated with live parasites. Eur J Immunol (1989) 1.12
Intralesional regulatory T-cell suppressive function during human acute and chronic cutaneous leishmaniasis due to Leishmania guyanensis. Infect Immun (2009) 1.12
The outcome of the parasitic process initiated by Leishmania infantum in laboratory mice: a tissue-dependent pattern controlled by the Lsh and MHC loci. J Immunol (1996) 1.09
Cyclosporin A inhibits the delayed-type hypersensitivity reaction: impaired production of early pro-inflammatory mediator(s). Eur J Immunol (1984) 1.09
Experimental models for leishmaniasis and for testing anti-leishmanial vaccines. Ann Trop Med Parasitol (1995) 1.07
Interleukin (IL)-13 is the predominant Th2 cytokine in localized cutaneous leishmaniasis lesions and renders specific CD4+ T cells unresponsive to IL-12. J Infect Dis (2001) 1.06
Regulation of protective immunity against Leishmania major in mice. Curr Opin Immunol (1998) 1.06
Trafficking of Plasmodium chabaudi adami-infected erythrocytes within the mouse spleen. Proc Natl Acad Sci U S A (1996) 1.05
Genotypes, antibiotic resistance profiles and microarray-based characterization of methicillin-resistant Staphylococcus aureus strains isolated from livestock and veterinarians in Switzerland. Zoonoses Public Health (2010) 1.05
Peptide-primed CD4+ cells and malaria sporozoites. Immunol Lett (1990) 1.05
Leishmania major-specific CD8+ T cells are inducers and targets of nitric oxide produced by parasitized macrophages. Eur J Immunol (1994) 1.04
An isoelectric focusing method for the study of the humoral response against the antigen 85 complex of Mycobacterium bovis BCG in the different forms of leprosy. J Immunol Methods (1991) 1.03
Humoral responses against the 85A and 85B antigens of Mycobacterium bovis BCG in patients with leprosy and tuberculosis. J Clin Microbiol (1992) 1.03
High intralesional interleukin-10 messenger RNA expression in localized cutaneous leishmaniasis is associated with unresponsiveness to treatment. J Infect Dis (2001) 1.02
Induction by specific T lymphocytes of intracellular destruction of Leishmania major in infected murine macrophages. Parasite Immunol (1984) 1.02
Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas. Oncogene (2001) 0.99