Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins.

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Published in Proc Natl Acad Sci U S A on August 29, 2000

Authors

E M Rego1, L Z He, R P Warrell, Z G Wang, P P Pandolfi

Author Affiliations

1: Department of Human Genetics, Molecular Biology Program, and Department of Medicine, Molecular Therapeutics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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