Published in J Clin Oncol on September 01, 2000
Tissue-selective therapy of cancer. Br J Cancer (2003) 1.59
Estrogen and androgen signaling in the pathogenesis of BPH. Nat Rev Urol (2011) 1.52
Cyclin A is a prognostic indicator in early stage breast cancer with and without tamoxifen treatment. Br J Cancer (2002) 1.43
Functional implications of altered subcellular localization of PELP1 in breast cancer cells. Cancer Res (2005) 1.39
Twist contributes to hormone resistance in breast cancer by downregulating estrogen receptor-α. Oncogene (2011) 1.34
Oncogenic potential of the nuclear receptor coregulator proline-, glutamic acid-, leucine-rich protein 1/modulator of the nongenomic actions of the estrogen receptor. Cancer Res (2007) 1.28
Estrogen receptor prevents p53-dependent apoptosis in breast cancer. Proc Natl Acad Sci U S A (2012) 1.15
Endocrinology and hormone therapy in breast cancer: new insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancer. Breast Cancer Res (2005) 1.12
A review of coumarin derivatives in pharmacotherapy of breast cancer. Curr Med Chem (2008) 1.03
Orphan nuclear receptors as targets for drug development. Pharm Res (2010) 0.97
Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice. BMC Genomics (2007) 0.95
Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1. Mol Endocrinol (2009) 0.94
Inferring predominant pathways in cellular models of breast cancer using limited sample proteomic profiling. BMC Cancer (2010) 0.90
Current medical treatment of estrogen receptor-positive breast cancer. World J Biol Chem (2015) 0.90
Methylation patterns in cell-free plasma DNA reflect removal of the primary tumor and drug treatment of breast cancer patients. Int J Cancer (2010) 0.89
Chemical modification modulates estrogenic activity, oxidative reactivity, and metabolic stability in 4'F-DMA, a new benzothiophene selective estrogen receptor modulator. Chem Res Toxicol (2006) 0.88
An integrated microfluidic cell array for apoptosis and proliferation analysis induction of breast cancer cells. Biomicrofluidics (2010) 0.87
Effects of tamoxifen versus raloxifene on retinal capillary endothelial cell proliferation. J Ocul Pharmacol Ther (2011) 0.86
Diethylstilbestrol increases the density of prolactin cells in male mouse pituitary by inducing proliferation of prolactin cells and transdifferentiation of gonadotropic cells. Histochem Cell Biol (2006) 0.85
Nitric oxide and MPP+-induced hydroxyl radical generation. J Neural Transm (Vienna) (2006) 0.85
CITED2 modulates estrogen receptor transcriptional activity in breast cancer cells. Biochem Biophys Res Commun (2013) 0.84
Calcium and vitamin D supplementation and loss of bone mineral density in women undergoing breast cancer therapy. Crit Rev Oncol Hematol (2013) 0.84
A DNA repair BRCA1 estrogen receptor and targeted therapy in breast cancer. Int J Mol Sci (2012) 0.83
Identification of xenoestrogens in food additives by an integrated in silico and in vitro approach. Chem Res Toxicol (2009) 0.82
Spironolactone, a possible selective androgen receptor modulator, should be used with caution in patients with metastatic carcinoma of the prostate. BMJ Case Rep (2012) 0.82
Tristetraprolin represses estrogen receptor α transactivation in breast cancer cells. J Biol Chem (2014) 0.80
Effects of low-dose tamoxifen on breast cancer biomarkers Ki-67, estrogen and progesterone receptors. Int Semin Surg Oncol (2006) 0.80
Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells. PLoS One (2011) 0.79
Non-nuclear actions of estrogen: new targets for prevention and treatment of cardiovascular disease. Mol Interv (2002) 0.79
Breast cancer chemoprevention: beyond tamoxifen. Breast Cancer Res (2001) 0.76
Inhibition of mTOR signaling reduces PELP1-mediated tumor growth and therapy resistance. Mol Cancer Ther (2014) 0.76
Antileishmanial activity of the estrogen receptor modulator raloxifene. PLoS Negl Trop Dis (2014) 0.76
High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome. Gynecol Oncol (2016) 0.76
Postoperative endocrine therapy for invasive breast cancer. Cancer Treat Res (2009) 0.76
Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer. Mol Cell Proteomics (2015) 0.75
The wedelolactone derivative inhibits estrogen receptor-mediated breast, endometrial, and ovarian cancer cells growth. Biomed Res Int (2014) 0.75
Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors. Am J Physiol Lung Cell Mol Physiol (2015) 0.75
Characterization of ligand type of estrogen receptor by MD simulation and mm-PBSA free energy analysis. Int J Biochem Mol Biol (2011) 0.75
Effects of estrogen receptor modulators on cytoskeletal proteins in the central nervous system. Neural Regen Res (2017) 0.75
Stromal gene signatures in large-B-cell lymphomas. N Engl J Med (2008) 11.34
Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst (1993) 4.45
Light control of Arabidopsis development entails coordinated regulation of genome expression and cellular pathways. Plant Cell (2001) 3.60
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol. Genome Biol (2001) 3.55
Nonconvulsive seizures are common in critically ill children. Neurology (2011) 2.77
Histological and biological evolution of human premalignant breast disease. Endocr Relat Cancer (2001) 2.71
Statistical analysis of array expression data as applied to the problem of tamoxifen resistance. J Natl Cancer Inst (1999) 2.58
Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants. J Neurosci (1998) 2.57
Pandemic Influenza A (H1N1) 2009 and mortality in the United Kingdom: risk factors for death, April 2009 to March 2010. Euro Surveill (2010) 2.49
Rate of functional decline in Huntington's disease. Huntington Study Group. Neurology (2000) 2.49
A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus. Hum Genet (1998) 2.44
Comparisons of two methods for haplotype reconstruction and haplotype frequency estimation from population data. Am J Hum Genet (2001) 2.44
Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations. Am J Hum Genet (2000) 2.43
Virological analysis of fatal influenza cases in the United Kingdom during the early wave of influenza in winter 2010/11. Euro Surveill (2011) 2.40
Household exposure to passive cigarette smoking and serum micronutrient concentrations. Am J Clin Nutr (2000) 2.38
Evolution of an enzyme activity: crystallographic structure at 2-A resolution of cephalosporinase from the ampC gene of Enterobacter cloacae P99 and comparison with a class A penicillinase. Proc Natl Acad Sci U S A (1993) 2.34
Survival and complications in thalassemia. Ann N Y Acad Sci (2005) 2.25
The cell biology of osteoclast function. J Cell Sci (2000) 2.21
Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs. Lett Appl Microbiol (2008) 2.19
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. J Biol Chem (2001) 2.16
HER-2/neu amplification predicts poor survival in node-positive breast cancer. Cancer Res (1990) 2.14
Prognostic signs in the surgical management of plexiform neurofibroma: the Children's Hospital of Philadelphia experience, 1974-1994. J Pediatr (1997) 2.13
Clinical markers of early disease in persons near onset of Huntington's disease. Neurology (2001) 2.11
Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors. Structure (1999) 2.09
Qualitative semi-parametric test for genetic associations in case-control designs under structured populations. Ann Hum Genet (2003) 2.07
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions. J Biol Chem (2001) 2.07
Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci. J Natl Cancer Inst (1998) 2.06
A novel programed frameshift expresses the POL3 gene of retrotransposon Ty3 of yeast: frameshifting without tRNA slippage. Cell (1993) 2.00
Biological and clinical implications of heat shock protein 27,000 (Hsp27): a review. J Natl Cancer Inst (1993) 1.99
Travel time to hospital and treatment for breast, colon, rectum, lung, ovary and prostate cancer. Eur J Cancer (2008) 1.97
Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications. J Natl Cancer Inst (1993) 1.95
The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer. EMBO J (1994) 1.87
High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas. Clin Cancer Res (2000) 1.85
The human decatenation checkpoint. Proc Natl Acad Sci U S A (2001) 1.84
p53-based blood test for p53PIN3 and risk for sporadic ovarian cancer. Lancet (1995) 1.84
Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly. Mol Biol Cell (1996) 1.83
An estrogen receptor mutant with strong hormone-independent activity from a metastatic breast cancer. Cancer Res (1997) 1.82
Genetic aberrations detected by comparative genomic hybridization predict outcome in node-negative breast cancer. Am J Pathol (1995) 1.81
The influence of chronic disease on resource utilization in common acute pediatric conditions. Financial concerns for children's hospitals. Arch Pediatr Adolesc Med (1999) 1.77
Estrogen receptor and breast cancer. Semin Cancer Biol (2001) 1.77
Crystallographic mapping of beta-lactams bound to a D-alanyl-D-alanine peptidase target enzyme. J Mol Biol (1989) 1.76
CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition. Proc Natl Acad Sci U S A (1995) 1.76
Loss of heterozygosity at D14S62 and metastatic potential of breast cancer. J Natl Cancer Inst (1999) 1.75
MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen. Cancer Res (1997) 1.74
Estrogen receptor variants in clinical breast cancer. Mol Endocrinol (1991) 1.73
Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Mol Ther (2000) 1.73
Differential expression of pleiotrophin and midkine in advanced neuroblastomas. Cancer Res (1995) 1.72
The bladder as a bioreactor: urothelium production and secretion of growth hormone into urine. Nat Biotechnol (1998) 1.71
The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012. Euro Surveill (2012) 1.67
Extent and consistency across generations of linkage disequilibrium in commercial layer chicken breeding populations. Genetics (2005) 1.64
A new model for phenotypic suppression of frameshift mutations by mutant tRNAs. Mol Cell (1998) 1.63
The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression. J Biol Chem (2000) 1.62
Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning. Neuroscience (2007) 1.61
Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3". Am J Hum Genet (1996) 1.59
Predictors of assistive technology abandonment. Assist Technol (1993) 1.59
Some views about the controversial dewetting morphology of polystyrene films. Eur Phys J E Soft Matter (2004) 1.57
A fluorimetric enzyme assay for the diagnosis of Morquio disease type A (MPS IV A). Clin Chim Acta (1990) 1.57
Magnetic resonance imaging of the upper airway in children with Down syndrome. Am J Respir Crit Care Med (2001) 1.54
The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res (1993) 1.54
In vivo phase variation of Escherichia coli type 1 fimbrial genes in women with urinary tract infection. Infect Immun (1998) 1.50
Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo. J Natl Cancer Inst (2000) 1.50
Longitudinal evaluation of cardiopulmonary performance during exercise after bone marrow transplantation in children. J Pediatr (2000) 1.49
MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma. Clin Cancer Res (2001) 1.46
Targeted gene silencing of TLR4 using liposomal nanoparticles for preventing liver ischemia reperfusion injury. Am J Transplant (2011) 1.43
Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility. Epilepsy Res (2004) 1.42
A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations. J Mol Biol (2000) 1.42
Assembly and entry mechanisms of Semliki Forest virus. Arch Virol Suppl (1994) 1.42
Relationship between ABO blood groups and carcinoma of esophagus and cardia in Chaoshan inhabitants of China. World J Gastroenterol (2001) 1.42
Obesity is a risk factor for acute mountain sickness: a prospective study in Tibet railway construction workers on Tibetan plateau. Eur Rev Med Pharmacol Sci (2015) 1.41
TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors. J Clin Oncol (2000) 1.38
Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1. Br J Pharmacol (2009) 1.37
Time of symptom onset of eight common medical emergencies. J Emerg Med (1995) 1.37
Measurement of steroid hormone receptors in breast cancer patients on tamoxifen. Breast Cancer Res Treat (1993) 1.36
A multicentre study assessing the prevalence of sensitizations in patients with asthma and/or rhinitis in China. Allergy (2009) 1.33
Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma. Proc Natl Acad Sci U S A (2000) 1.33
Small cell neuroendocrine carcinoma of the cervix: Analysis of outcome, recurrence pattern and the impact of platinum-based combination chemotherapy. Gynecol Oncol (2008) 1.32
Uptake and impact of a new live attenuated influenza vaccine programme in England: early results of a pilot in primary school-age children, 2013/14 influenza season. Euro Surveill (2014) 1.32
Doxorubicin-induced apoptosis is associated with increased transcription of endothelial nitric-oxide synthase. Effect of antiapoptotic antioxidants and calcium. J Biol Chem (2001) 1.32
Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130. J Biol Chem (1998) 1.31
Response of human breast cancer cells to heat shock and chemotherapeutic drugs. Cancer Res (1992) 1.30
The effects of genotyping errors and interference on estimation of genetic distance. Hum Hered (1997) 1.29
Specific interaction in vitro and in vivo of glyceraldehyde-3-phosphate dehydrogenase and LA protein with cis-acting RNAs of human parainfluenza virus type 3. J Biol Chem (1996) 1.29
Social support mediates the relationship between HIV stigma and depression/quality of life among people living with HIV in Beijing, China. Int J STD AIDS (2012) 1.29
Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor. Mol Endocrinol (1989) 1.27
Experimental demonstration of isotropic negative permeability in a three-dimensional dielectric composite. Phys Rev Lett (2008) 1.27
Social and geographical factors affecting access to treatment of lung cancer. Br J Cancer (2009) 1.26
Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor. Proc Natl Acad Sci U S A (1998) 1.25
Estrogen receptor: current understanding of its activation and modulation. Clin Cancer Res (2001) 1.25
Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice. Acta Anaesthesiol Scand (2011) 1.25
Conceptualizing antiretroviral adherence in Beijing, China. AIDS Care (2008) 1.23
Expression and function of a nonglycosylated major histocompatibility class I antigen. J Exp Med (1986) 1.22
The angiogenesis inhibitor tnp-470 effectively inhibits human neuroblastoma xenograft growth, especially in the setting of subclinical disease. Clin Cancer Res (2001) 1.22
Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphism. Cancer Res (1989) 1.22
Acute regulation of Na+/H+ exchanger NHE3 by parathyroid hormone via NHE3 phosphorylation and dynamin-dependent endocytosis. J Biol Chem (2000) 1.22
Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification. Oncogene (2007) 1.21
alpha-MSH and its receptors in regulation of tumor necrosis factor-alpha production by human monocyte/macrophages. Am J Physiol (1999) 1.21
Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus. Proc Natl Acad Sci U S A (1995) 1.21
Hsp27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells. Breast Cancer Res Treat (1999) 1.21
Mapping the DNA binding domain of the Zap1 zinc-responsive transcriptional activator. J Biol Chem (2000) 1.21
Prognostic significance of p53 gene alterations in node-negative breast cancer. Breast Cancer Res Treat (1993) 1.20