Replication-dependent early meiotic requirement for Spo11 and Rad50.

PubWeight™: 1.03‹?› | Rank: Top 15%

🔗 View Article (PMC 27049)

Published in Proc Natl Acad Sci U S A on September 12, 2000

Authors

S T Merino1, W J Cummings, S N Acharya, M E Zolan

Author Affiliations

1: Department of Biology, Indiana University, Bloomington, IN 47405, USA.

Articles citing this

Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol Mol Biol Rev (2004) 3.67

Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2. Genes Dev (2001) 2.23

From early homologue recognition to synaptonemal complex formation. Chromosoma (2006) 2.15

Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis. Genome Dyn Stab (2008) 2.03

An expanded inventory of conserved meiotic genes provides evidence for sex in Trichomonas vaginalis. PLoS One (2007) 1.67

The axial element protein HTP-3 promotes cohesin loading and meiotic axis assembly in C. elegans to implement the meiotic program of chromosome segregation. Genes Dev (2009) 1.62

Targeted gene knockout reveals a role in meiotic recombination for ZHP-3, a Zip3-related protein in Caenorhabditis elegans. Mol Cell Biol (2004) 1.45

The multiple roles of the Mre11 complex for meiotic recombination. Chromosome Res (2007) 1.31

Distinct functions of S. pombe Rec12 (Spo11) protein and Rec12-dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II. Cell Chromosome (2002) 1.23

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. Genes Dev (2010) 1.21

A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thaliana. PLoS Genet (2009) 1.16

Meiotic defects in the Arabidopsis rad50 mutant point to conservation of the MRX complex function in early stages of meiotic recombination. Chromosoma (2004) 1.08

Intron gain and loss in the evolution of the conserved eukaryotic recombination machinery. Nucleic Acids Res (2002) 1.02

The Saccharomyces cerevisiae MUM2 gene interacts with the DNA replication machinery and is required for meiotic levels of double strand breaks. Genetics (2001) 1.02

A model for chromosome structure during the mitotic and meiotic cell cycles. Chromosome Res (2001) 0.98

Analysis of the Basidiomycete Coprinopsis cinerea reveals conservation of the core meiotic expression program over half a billion years of evolution. PLoS Genet (2010) 0.89

Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination. Genetics (2008) 0.88

The Coprinus cinereus adherin Rad9 functions in Mre11-dependent DNA repair, meiotic sister-chromatid cohesion, and meiotic homolog pairing. Proc Natl Acad Sci U S A (2002) 0.86

Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination. Nucleic Acids Res (2012) 0.86

Comparative transcriptomics of the model mushroom Coprinopsis cinerea reveals tissue-specific armories and a conserved circuitry for sexual development. BMC Genomics (2014) 0.86

Meiotic recombination protein Rec12: functional conservation, crossover homeostasis and early crossover/non-crossover decision. Nucleic Acids Res (2010) 0.84

An MSH4 homolog, stpp1, from Pleurotus pulmonarius is a "silver bullet" for resolving problems caused by spores in cultivated mushrooms. Appl Environ Microbiol (2013) 0.81

Meiotic localization of Mre11 and Rad50 in wild type, spo11-1, and MRN complex mutants of Coprinus cinereus. Chromosoma (2009) 0.75

Articles cited by this

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family. Cell (1997) 10.32

Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster. Genetics (1972) 7.86

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell (1990) 7.85

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol (1996) 7.33

Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis. Cell (1998) 6.32

Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae. Genetics (1985) 5.75

The synaptonemal complex in genetic segregation. Annu Rev Genet (1984) 5.53

A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell (1997) 5.49

The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes Dev (1994) 5.20

In situ visualization of DNA double-strand break repair in human fibroblasts. Science (1998) 4.53

A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis. Cell (1999) 4.42

Electron microscopic observations on the meiotic karyotype of diploid and tetraploid Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1975) 4.36

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol Cell Biol (1999) 4.32

Chromosome pairing via multiple interstitial interactions before and during meiosis in yeast. Cell (1994) 4.23

DNA double-strand breaks caused by replication arrest. EMBO J (1997) 4.18

The many interfaces of Mre11. Cell (1998) 4.14

Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell (1998) 3.80

Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Genetics (1995) 3.57

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55

Meiotic synapsis in the absence of recombination. Science (1998) 3.48

Meiosis: how could it work? Proc Natl Acad Sci U S A (1996) 3.40

Cohesin Rec8 is required for reductional chromosome segregation at meiosis. Nature (1999) 3.35

DNA recombination: the replication connection. Trends Biochem Sci (1999) 3.32

XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination. Genetics (1992) 3.15

mei-W68 in Drosophila melanogaster encodes a Spo11 homolog: evidence that the mechanism for initiating meiotic recombination is conserved. Genes Dev (1998) 2.82

SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates? Genes Dev (1999) 2.77

The Utilization during Mitotic Cell Division of Loci Controlling Meiotic Recombination and Disjunction in DROSOPHILA MELANOGASTER. Genetics (1978) 2.75

mre11S--a yeast mutation that blocks double-strand-break processing and permits nonhomologous synapsis in meiosis. Genes Dev (1997) 2.61

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.51

Progression of meiotic DNA replication is modulated by interchromosomal interaction proteins, negatively by Spo11p and positively by Rec8p. Genes Dev (2000) 2.34

Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11. Genetics (1998) 2.32

DNA-mediated transformation of the basidiomycete Coprinus cinereus. EMBO J (1987) 2.32

CLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint. Genes Dev (1998) 2.18

Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase. Genes Dev (1998) 2.10

The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast. Curr Genet (1990) 1.93

Gene conversion at different points in the mitotic cycle of Saccharomyces cerevisiae. Mol Gen Genet (1984) 1.88

Chromosome segregation during meiosis: building an unambivalent bivalent. Curr Top Dev Biol (1998) 1.83

The SMC family: from chromosome condensation to dosage compensation. Curr Opin Cell Biol (1995) 1.68

A postprophase topoisomerase II-dependent chromatid core separation step in the formation of metaphase chromosomes. J Cell Biol (1995) 1.65

Genetic control of chromosome synapsis in yeast meiosis. Genome (1989) 1.50

Multiple roles of Spo11 in meiotic chromosome behavior. EMBO J (2000) 1.46

The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis. Genetics (1998) 1.24

Morphogenesis of the synapton during yeast meiosis. Chromosoma (1979) 1.18

Production and characterization of radiation-sensitive meiotic mutants of Coprinus cinereus. Genetics (1988) 1.08

Effects of the mitotic cell-cycle mutation cdc4 on yeast meiosis. Genetics (1977) 1.07

Insertional mutagenesis in Coprinus cinereus: use of a dominant selectable marker to generate tagged, sporulation-defective mutants. Curr Genet (1999) 1.01

Chromosome dynamics in rad12 mutants of Coprinus cinereus. Chromosoma (1995) 0.92

Multiple mutant analysis of recombination in yeast. Mol Gen Genet (1983) 0.89

Sequential immunocytogenetics, molecular cytogenetics and transmission electron microscopy of microspread meiosis I oocytes from a human fetal carrier of an unbalanced translocation. Chromosoma (1997) 0.80

Articles by these authors

Inheritance of DNA methylation in Coprinus cinereus. Mol Cell Biol (1986) 4.78

Multiple roles of Spo11 in meiotic chromosome behavior. EMBO J (2000) 1.46

Isolation and characterization of rad51 orthologs from Coprinus cinereus and Lycopersicon esculentum, and phylogenetic analysis of eukaryotic recA homologs. Curr Genet (1997) 1.38

Deficient repair of chemical adducts in alpha DNA of monkey cells. Cell (1982) 1.27

The rad9 gene of Coprinus cinereus encodes a proline-rich protein required for meiotic chromosome condensation and synapsis. Genetics (1996) 1.20

Molecular analysis of pcc1, a gene that leads to A-regulated sexual morphogenesis in Coprinus cinereus. Genetics (1998) 1.03

Insertional mutagenesis in Coprinus cinereus: use of a dominant selectable marker to generate tagged, sporulation-defective mutants. Curr Genet (1999) 1.01

An mre11 mutant of Coprinus cinereus has defects in meiotic chromosome pairing, condensation and synapsis. Genetics (2000) 1.01

Restricted repair of aflatoxin B1 induced damage in alpha DNA of monkey cells. Nucleic Acids Res (1983) 0.98

Pathway analysis of radiation-sensitive meiotic mutants of Coprinus cinereus. Mol Gen Genet (1995) 0.98

A case of osteochondroma of the cervical spine. Skeletal Radiol (1995) 0.93

Chromosome dynamics in rad12 mutants of Coprinus cinereus. Chromosoma (1995) 0.92

Formation and repair of furocoumarin adducts in alpha deoxyribonucleic acid and bulk deoxyribonucleic acid of monkey cells. Biochemistry (1984) 0.88

Homolog pairing and meiotic progression in Coprinus cinereus. Chromosoma (1999) 0.86

Spermatozoa Production by Triploid Males in the New Zealand Freshwater Snail Potamopyrgus antipodarum. Biol J Linn Soc Lond (2013) 0.84

Macrorestriction analysis of Caenorhabditis elegans genomic DNA. Genetics (1996) 0.84

Rearrangement of mammalian chromatin structure following excision repair. Nature (1982) 0.83

Functions of DNA repair genes during meiosis. Curr Top Dev Biol (1998) 0.79

Repair responses to DNA damage: enzymatic pathways in E coli and human cells. J Cell Biochem (1982) 0.77

Screening of condensed tannins from Canadian prairie forages for anti-Escherichia coli O157:H7 with an emphasis on purple prairie clover (Dalea purpurea Vent). J Food Prot (2013) 0.77

Comparison of the ruminal metabolism of nitrogen from 15N-labeled alfalfa preserved as hay or as silage. J Dairy Sci (2001) 0.75

Repair of furocoumarin adducts in mammalian cells. Natl Cancer Inst Monogr (1984) 0.75

Evidence for a three-nucleon-force effect in proton-deuteron elastic scattering. Phys Rev Lett (2001) 0.75