Published in N Engl J Med on September 18, 1975
Platelet factor 4 is chemotactic for neutrophils and monocytes. Proc Natl Acad Sci U S A (1981) 3.03
Platelet membrane defects in Glanzmann's thrombasthenia. Evidence for decreased amounts of two major glycoproteins. J Clin Invest (1977) 2.43
Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF. J Clin Invest (2008) 2.43
Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice. J Exp Med (2001) 1.75
The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress. J Clin Invest (1991) 1.66
The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization. J Clin Invest (1977) 1.58
Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions. J Clin Invest (1998) 1.40
Platelet adhesion under flow. Microcirculation (2009) 1.31
Old concepts and new developments in the study of platelet aggregation. J Clin Invest (2000) 1.22
Role of shear rate and platelets in promoting fibrin formation on rabbit subendothelium. Studies utilizing patients with quantitative and qualitative platelet defects. J Clin Invest (1986) 1.13
The effects of ristocetin and von Willebrand factor on platelet electrophoretic mobility. J Clin Invest (1978) 1.01
Effect of dextran on factor VIII (antihemophilic factor) and platelet function. Ann Surg (1979) 0.93
Flow-induced structural transition in the beta-switch region of glycoprotein Ib. Biophys J (2008) 0.91
Disorders of platelet function: mechanisms, diagnosis and management. West J Med (1981) 0.87
Unravelling the mechanism and significance of thrombin binding to platelet glycoprotein Ib. Thromb Haemost (2010) 0.84
The prostanoids in hemostasis and thrombosis: a review. Am J Pathol (1980) 0.83
Mechanobiology of platelets: techniques to study the role of fluid flow and platelet retraction forces at the micro- and nano-scale. Int J Mol Sci (2011) 0.83
The effect of oral phenylbutazone on whole blood platelet aggregation in the dog. Can J Comp Med (1985) 0.81
Functional platelets after storage in vitro for 15--21 days. Am J Pathol (1980) 0.78
Flow-induced beta-hairpin folding of the glycoprotein Ibalpha beta-switch. Biophys J (2010) 0.78
Role of platelets in hemostasis and thrombosis. West J Med (1976) 0.77
The thrombotic potential of oral pathogens. J Oral Microbiol (2009) 0.75
Platelet mitochondrial dysfunction in critically ill patients: comparison between sepsis and cardiogenic shock. Crit Care (2015) 0.75
A Novel Model of Intravital Platelet Imaging Using CD41-ZsGreen1 Transgenic Rats. PLoS One (2016) 0.75
Platelet function testing. West J Med (1978) 0.75
Impaired platelet-connective-tissue reaction in man after aspirin ingestion. Lancet (1967) 5.38
The effect of salicylates on the hemostatic properties of platelets in man. J Clin Invest (1968) 3.66
Quantitative assay of a plasma factor deficient in von Willebrand's disease that is necessary for platelet aggregation. Relationship to factor VIII procoagulant activity and antigen content. J Clin Invest (1973) 2.94
Defective ristocetin-induced platelet aggregation in von Willebrand's disease and its correction by factor VIII. J Clin Invest (1973) 2.71
Decreased adhesion of platelets to subendothelium in von Willebrand's disease. J Lab Clin Med (1974) 2.44
Platelet physiology and abnormalities of platelet function (first of two parts). N Engl J Med (1975) 2.31
Studies of the release from human platelets of the growth factor for cultured human arterial smooth muscle cells. Circ Res (1978) 2.14
Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium. Further implications on the role of the von Willebrand factor in hemostasis. Am J Med (1974) 1.86
Transient arthritis after rubella vaccination. Am J Dis Child (1969) 1.86
Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease. J Clin Invest (1977) 1.85
Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity. J Biol Chem (1989) 1.63
Separation of sub-units of antihemophilic factor (AHF) by agarose gel chromatography. Thromb Diath Haemorrh (1972) 1.61
Molecular forms of antihaemophilic globulin in plasma, cryoprecipitate and after thrombin activation. Br J Haematol (1970) 1.57
Secretable storage pools in platelets. Annu Rev Med (1979) 1.49
Von Willebrand factor: dissociation from antihemophilic factor procoagulant activity. Science (1973) 1.49
Gender-related differences in thrombogenic factors predicting recurrent cardiac events in patients after acute myocardial infarction. The THROMBO Investigators. Am J Cardiol (2000) 1.47
Aspirin--a dangerous drug? JAMA (1974) 1.47
Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate--dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome. J Lab Clin Med (1978) 1.46
Fibrinogen and platelets in the primary arrest of bleeding. Studies in two patients with congenital afibrinogenemia. N Engl J Med (1971) 1.46
Correction by factor VIII of the impaired platelet adhesion to subendothelium in von Willebrand disease. Blood (1978) 1.39
Thrombogenic factors and recurrent coronary events. Circulation (1999) 1.38
Prostacyclin (prostaglandin I2, PGI2) inhibits platelet adhesion and thrombus formation on subendothelium. Blood (1979) 1.33
Pseudo-von Willebrand's disease. An intrinsic platelet defect with aggregation by unmodified human factor VIII/von Willebrand factor and enhanced adsorption of its high-molecular-weight multimers. N Engl J Med (1982) 1.26
Correction of the platelet abnormality in von Willebrand's disease by cryoprecipitate. Am J Med (1972) 1.25
Studies of platelet function and proteins in 3 patients with Glanzmann's thrombasthenia. J Lab Clin Med (1968) 1.24
Hereditary defect in the platelet release reaction caused by a deficiency in the storage pool of platelet adenine nucleotides. Br J Haematol (1970) 1.23
Further evidence for a deficient storage pool of adenine nucleotides in platelets from some patients with thrombocytopathia--"storage pool disease". Blood (1972) 1.23
Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoproteins IIb-IIIa, Ib, and storage granules. Blood (1986) 1.21
Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesion. J Clin Invest (1984) 1.20
A familialdefect in platelet function associated with imapired release of adenosine diphosphate. N Engl J Med (1969) 1.18
Platelet membrane glycoproteins in thrombasthenia, Bernard-Soulier syndrome, and storage pool disease. J Lab Clin Med (1979) 1.17
A congenital defect in platelet prostaglandin production associated with impaired hemostasis in storage pool disease. Prostaglandins (1973) 1.17
Platelet aggregation, adhesion and adenosine diphosphate release in thrombopathia (platelet factor 3 deficiency). A comparison with Glanzmann's thrombasthenia and von Willebrand's disease. Am J Med (1967) 1.16
Isolated deficiency of platelet procoagulant activity. Am J Med (1979) 1.15
Red blood cells: their dual role in thrombus formation. Science (1980) 1.13
Role of shear rate and platelets in promoting fibrin formation on rabbit subendothelium. Studies utilizing patients with quantitative and qualitative platelet defects. J Clin Invest (1986) 1.13
Thrombocytopathia due to abnormalities in platelet release reaction--studies on six unrelated patients. Blood (1972) 1.12
Dependence of human platelet functional responses on divalent cations: aggregation and secretion in heparin- and hirudin-anticoagulated platelet-rich plasma and the effects of chelating agents. Thromb Haemost (1981) 1.07
Editorial: Platelet function tests and their interpretation. J Lab Clin Med (1976) 1.06
Heterogeneous abnormalities in the multimeric structure, antigenic properties, and plasma-platelet content of factor VIII/von Willebrand factor in subtypes of classic (type I) and variant (type IIA) von Willebrand's disease. J Lab Clin Med (1983) 1.06
Von Willebrand's disease--diagnostic criteria. Blood (1968) 1.06
Factor VIII/von Willebrand factor in subendothelium mediates platelet adhesion. Blood (1985) 1.05
Studies of platelet 5-hydroxytryptamine (serotonin) in storage pool disease and albinism. J Clin Invest (1974) 1.03
Antiplatelet therapy (first of two parts). N Engl J Med (1978) 1.02
Content and thrombin-induced release of acid hydrolases in gel-filtered platelets from patients with storage pool disease. Blood (1975) 1.02
Properties of the platelet retention (von Willebrand) factor and its similarity to the antihemophilic factor (AHF). Blood (1973) 1.01
Thromboembolism--a continuing challenge. N Engl J Med (1970) 0.97
Impaired factor X and prothrombin activation associated with decreased phospholipid exposure in platelets from a patient with a bleeding disorder. Blood (1985) 0.97
The effect of shear rate on platelet interaction with subendothelium exposed to citrated human blood. Microvasc Res (1980) 0.96
Decreased platelet adhesion on vessel segments in von Willebrand's disease: a defect in initial platelet attachment. J Lab Clin Med (1983) 0.95
Release of human platelet factor V activity is induced by both collagen and ADP and is inhibited by aspirin. Blood (1980) 0.95
Ultrastructural findings in storage pool disease and aspirin-like defects of platelets. Am J Pathol (1973) 0.94
Impaired interaction (adhesion-aggregation) of platelets with the subendothelium in storage-pool disease and after aspirin ingestion. A comparison with von Willebrand's disease. N Engl J Med (1975) 0.94
The effect of clinical dextran on platelet aggregation, adhesion, and ADP release in man: in vivo and in vitro studies. J Lab Clin Med (1967) 0.94
Platelet interaction with collagen fibrils in flowing blood. II. Impaired adhesion-aggregation in bleeding disorders. A comparison with subendothelium. Thromb Haemost (1977) 0.93
Production and characterization of transformed B-lymphocytes expressing the membrane defect of Scott syndrome. J Clin Invest (1994) 0.92
Antiplatelet drugs-a new pharmacologic approach to the prevention of thrombosis. Am Heart J (1976) 0.90
Phylogenetic studies with pemphigus and pemphigoid antibodies. Acta Derm Venereol (1978) 0.90
Enhanced increases in cytosolic Ca2+ in ADP-stimulated platelets from patients with delta-storage pool deficiency--a possible indicator of interactions between granule-bound ADP and the membrane ADP receptor. Thromb Haemost (1997) 0.89
Glycoprotein IIb Leu214Pro mutation produces glanzmann thrombasthenia with both quantitative and qualitative abnormalities in GPIIb/IIIa. Blood (1998) 0.89
Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. II. Relationships among platelet adhesion, thrombus dimensions, and fibrin formation. J Lab Clin Med (1980) 0.89
Metal ion contents of gel-filtered platelets from patients with storage pool disease. Blood (1975) 0.88
Effects of puff adder venom on the coagulation mechanism. I. In vivo. Toxicon (1973) 0.88
Afibrinogenemia in man following the bite of a rattlesnake (Crotalus adamanteus). Am J Med (1969) 0.88
Deficiency of glutathione peroxidase associated with high levels of reduced glutathione in glanzmann's thrombasthenia. N Engl J Med (1972) 0.86
Incidence of severe von Willebrand's disease. N Engl J Med (1982) 0.86
Scott syndrome erythrocytes contain a membrane protein capable of mediating Ca2+-dependent transbilayer migration of membrane phospholipids. J Clin Invest (1997) 0.85
Acetylenic analog of arachidonate that acts like aspirin on platelets. Science (1974) 0.85
Family studies in Scott syndrome. Blood (1997) 0.85
Congenital disorders of platelet function. Semin Hematol (1980) 0.84
Platelet factor 4 in platelet disorders--storage location and the requirement of endogenous ADP for its release. Proc Soc Exp Biol Med (1973) 0.84
Inhibition of human platelet function in vitro and ex vivo by acetaminophen. Thromb Res (1989) 0.84
Platelet alpha granule deficiency associated with decreased P-selectin and selective impairment of thrombin-induced activation in a new patient with gray platelet syndrome (alpha-storage pool deficiency). J Lab Clin Med (1997) 0.84
Abnormalities in platelet function due to defects in the release reaction. Ann N Y Acad Sci (1972) 0.83
Increased level of von Willebrand factor is significantly and independently associated with diabetes in postinfarction patients. THROMBO Investigators. Thromb Haemost (2001) 0.82
Decreased content and surface expression of alpha-granule membrane protein GMP-140 in one of two types of platelet alpha delta storage pool deficiency. J Clin Invest (1991) 0.82
Impaired platelet response to thromboxane-A2 and defective calcium mobilization in a patient with a bleeding disorder. Blood (1981) 0.82
Heterogeneous defects of platelet secretion and responses to weak agonists in patients with bleeding disorders. Br J Haematol (1988) 0.82
Decreased ATP, ADP and serotonin in young platelets of fawn-hooded rats with storage pool disease. Thromb Diath Haemorrh (1974) 0.82
Letter: Nature of the von Willebrand factors. N Engl J Med (1974) 0.81
Cells and aggregates at surfaces. Ann N Y Acad Sci (1987) 0.81
The phospholipid and fatty acid composition of platelets in patients with primary defects of platelet function. Lipids (1972) 0.81
Aspirin ingestion compared with bleeding disorders--search for a useful platelet antiaggregant. Blood (1970) 0.81
Protection by aspirin against experimentally induced arterial thrombosis in dogs. Thromb Diath Haemorrh (1971) 0.80
Fatal disseminated intravascular coagulation and hemolytic anemia following stibophen therapy: a study of basic mechanisms. Am J Med Sci (1972) 0.80
Interaction of thrombasthenic platelets with subendothelium: normal adhesion, absent aggregation. Experientia (1975) 0.80
Spontaneous aggregation of low molecular weight factor viii and its prevention by 2mm cacl2. Thromb Res (1976) 0.80
Prostaglandin E2 potentiation of platelet aggregation induced by LASS endoperoxide: absent in storage pool disease, normal after aspirin ingestion. Br J Haematol (1976) 0.80
Specific correction of impaired acid hydrolase secretion in storage pool-deficient platelets by adenosine diphosphate. J Clin Invest (1988) 0.80
Biphasic aggregation responses to ADP and epinephrine in some storage pool deficient platelets: relationship to the role of endogenous ADP in platelet aggregation and secretion. Thromb Haemost (1980) 0.79
Effect of aspirin and dipyridamole on the interaction of human platelets with sub-endothelium: studies using citrated and native blood. Thromb Haemost (1981) 0.79
Antihaemophilic globulin (AHG) in multiple myeloma and macroglobulinaemia. Br J Haematol (1968) 0.79