Published in J Investig Med on September 01, 2000
Resolution of bronchial inflammation is related to bacterial eradication following treatment of exacerbations of chronic bronchitis. Thorax (2003) 1.20
Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation. J Immunol (2009) 1.07
A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress. Cell Stress Chaperones (2011) 1.05
Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD. Respir Res (2011) 1.04
The presence of elafin, SLPI, IL1-RA and STNFalpha RI in head and neck squamous cell carcinomas and their relation to the degree of tumour differentiation. Mediators Inflamm (2002) 1.00
Moraxella catarrhalis acquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease. BMC Infect Dis (2009) 0.89
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides. Respir Res (2011) 0.87
Periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid. Mol Oral Microbiol (2011) 0.86
Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells. PLoS Pathog (2015) 0.84
Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex. Respir Res (2008) 0.81
Various forms of tissue damage and danger signals following hematopoietic stem-cell transplantation. Front Immunol (2015) 0.81
Primary human bronchial epithelial cells grown from explants. J Vis Exp (2010) 0.81
Interleukin 13 exposure enhances vitamin D-mediated expression of the human cathelicidin antimicrobial peptide 18/LL-37 in bronchial epithelial cells. Infect Immun (2012) 0.80
Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin. Hum Mol Genet (2013) 0.78
Xenobiotic metabolism in differentiated human bronchial epithelial cells. Arch Toxicol (2016) 0.75
Uniquely altered transcripts are associated with immune preservation in HIV infection. PLoS One (2017) 0.75
ADAM17 and EGFR regulate IL-6 receptor and amphiregulin mRNA expression and release in cigarette smoke-exposed primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD). Physiol Rep (2016) 0.75
Nasal Levels of Antimicrobial Peptides in Allergic Asthma Patients and Healthy Controls: Differences and Effect of a Short 1,25(OH)2 Vitamin D3 Treatment. PLoS One (2015) 0.75
Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation. Front Physiol (2017) 0.75
Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy (2008) 12.35
Outcomes for COPD pharmacological trials: from lung function to biomarkers. Eur Respir J (2008) 5.38
The mechanisms of microbial oxidations of petroleum hydrocarbons. Adv Enzymol Relat Areas Mol Biol (1965) 3.91
Complex chronic comorbidities of COPD. Eur Respir J (2008) 3.84
Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3. Blood (2001) 3.49
Risk factors of frequent exacerbations in difficult-to-treat asthma. Eur Respir J (2005) 3.05
IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha. J Immunol (1992) 2.73
Innate immunity in the lung: how epithelial cells fight against respiratory pathogens. Eur Respir J (2004) 2.70
On the nature of hypertrophic scars and keloids: a review. Plast Reconstr Surg (1999) 2.55
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17
Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. Eur Respir J (1996) 2.05
Roflumilast with long-acting β2-agonists for COPD: influence of exacerbation history. Eur Respir J (2011) 1.99
Factors associated with persistent airflow limitation in severe asthma. Am J Respir Crit Care Med (2001) 1.88
Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo. Clin Exp Allergy (1997) 1.76
Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation. Lung Cancer (2006) 1.61
Relation between duration of smoking cessation and bronchial inflammation in COPD. Thorax (2005) 1.60
Densitometry for assessment of effect of lung volume reduction surgery for emphysema. Eur Respir J (2007) 1.60
Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD. Eur Respir J (2008) 1.59
Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1998) 1.59
Imaging of bacterial infections with 99mTc-labeled human neutrophil peptide-1. J Nucl Med (1999) 1.57
CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide. Clin Exp Allergy (2014) 1.56
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects. Am J Respir Crit Care Med (1997) 1.55
Monocyte chemoattractant protein 1, interleukin 8, and chronic airways inflammation in COPD. J Pathol (2000) 1.54
Basal membrane heparan sulphate proteoglycan expression during wound healing in human skin. J Pathol (1997) 1.50
Why are long-acting beta-adrenoceptor agonists long-acting? Eur Respir J (1994) 1.49
[Asthma therapy in children and adults. Recommendations of the German Respiratory League of the German Society of Pneumology]. Med Klin (Munich) (1998) 1.47
Low dose fenoterol aerosol protects against histamine-induced bronchoconstriction in mild asthmatics: a dose response study. Clin Exp Allergy (1992) 1.46
Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD. Eur Respir J (2007) 1.45
Variability of bronchial inflammation in chronic obstructive pulmonary disease: implications for study design. Eur Respir J (2006) 1.45
Pulmonary periarterial inflammation in fatal asthma. Clin Exp Allergy (2009) 1.42
[Combination of asthma and COPD: more frequent as considered to be?]. Pneumologie (2006) 1.40
Antileukoprotease: an endogenous protein in the innate mucosal defense against fungi. J Infect Dis (1997) 1.39
[beta(2)-Sympathomimetics: risks for asthma therapy? Lessons from the SMART1 Study. A statement from the German Respiratory Tract League]. Dtsch Med Wochenschr (2007) 1.39
Activation of the alternative pathway of complement by human serum IgA. Eur J Immunol (1987) 1.38
Histamine hypersensitivity induced by passive sensitization of human bronchus: effect of serum IgE depletion. Clin Exp Allergy (1998) 1.38
Distribution of inhaled fluticasone propionate between human lung tissue and serum in vivo. Eur Respir J (1997) 1.36
Effect of defensins on interleukin-8 synthesis in airway epithelial cells. Am J Physiol (1997) 1.34
Expression of Fas (CD95) and FasL (CD95L) in human airway epithelium. Am J Respir Cell Mol Biol (1998) 1.31
Airway inflammation in obese and nonobese patients with difficult-to-treat asthma. Allergy (2008) 1.31
Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis. Eur Respir J (2007) 1.30
IgA- and secretory IgA-opsonized S. aureus induce a respiratory burst and phagocytosis by polymorphonuclear leucocytes. Immunology (1987) 1.30
SKALP/elafin is an inducible proteinase inhibitor in human epidermal keratinocytes. J Cell Sci (1994) 1.30
Cationization of catalase, peroxidase, and superoxide dismutase. Effect of improved intraarticular retention on experimental arthritis in mice. J Clin Invest (1985) 1.27
Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan-stimulated respiratory burst by 'type IV'-selective PDE inhibitors. Br J Pharmacol (1991) 1.26
Antibacterial activity of human neutrophil defensins in experimental infections in mice is accompanied by increased leukocyte accumulation. J Clin Invest (1998) 1.25
Chronic obstructive pulmonary disease: role of bronchiolar mast cells and macrophages. Am J Pathol (1997) 1.25
Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper. Allergy (2010) 1.24
Induction of SLPI (ALP/HUSI-I) in epidermal keratinocytes. J Invest Dermatol (1998) 1.24
Asthma control and differences in management practices across seven European countries. Respir Med (2002) 1.21
Defensins: key players or bystanders in infection, injury, and repair in the lung? J Allergy Clin Immunol (1999) 1.21
Proteases from Aspergillus fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines. J Infect Dis (1997) 1.21
Human neutrophil defensin and serpins form complexes and inactivate each other. Am J Respir Cell Mol Biol (1995) 1.20
SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking. J Biol Chem (1993) 1.20
Antiglomerular basement membrane nephritis in beige mice. Deficiency of leukocytic neutral proteinases prevents the induction of albuminuria in the heterologous phase. J Exp Med (1989) 1.18
Hydrogen peroxide suppresses the proteoglycan synthesis of intact articular cartilage. J Rheumatol (1985) 1.17
Analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin LL-37 in the innate immune response against periodontogenic bacteria. Oral Microbiol Immunol (2008) 1.17
Anti-endothelial cell antibodies in patients with rheumatoid arthritis complicated by vasculitis. Clin Exp Immunol (1989) 1.17
Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia. J Clin Invest (1996) 1.15
The small airways and distal lung compartment in asthma and COPD: a time for reappraisal. Allergy (2009) 1.15
Effect of neutrophil serine proteinases and defensins on lung epithelial cells: modulation of cytotoxicity and IL-8 production. J Leukoc Biol (1997) 1.14
Proteinase 3, the major autoantigen of Wegener's granulomatosis, enhances IL-8 production by endothelial cells in vitro. J Am Soc Nephrol (1996) 1.14
Initiation of apoptosis by actin cytoskeletal derangement in human airway epithelial cells. Am J Respir Cell Mol Biol (2001) 1.13
Elastase secreted by activated polymorphonuclear leucocytes causes chondrocyte damage and matrix degradation in intact articular cartilage: escape from inactivation by alpha-1-proteinase inhibitor. Br J Exp Pathol (1987) 1.13
Ciliogenesis in human bronchial epithelial cells cultured at the air-liquid interface. Am J Respir Cell Mol Biol (1994) 1.12
Decreased PMN accumulation and glomerular damage by clodronate liposome treatment in PMN-dependent anti-GBM nephritis in mice. Exp Nephrol (1997) 1.10
Predominance of left-sided deep vein thrombosis and body weight. J Thromb Haemost (2010) 1.10
Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of sarcoidosis. Eur Respir J (2005) 1.09
Secretory leukoprotease inhibitor: a native antimicrobial protein presenting a new therapeutic option? Thorax (1998) 1.09
Passive sensitization of human bronchi augments smooth muscle shortening velocity and capacity. Am J Physiol (1994) 1.09
Poor asthma control in children: evidence from epidemiological surveys and implications for clinical practice. Int J Clin Pract (2006) 1.09
The European Union conference on chronic respiratory disease: purpose and conclusions. Eur Respir J (2011) 1.08
Towards a minimally invasive staging strategy in NSCLC: analysis of PET positive mediastinal lesions by EUS-FNA. Lung Cancer (2004) 1.08
Regulation of SLPI and elafin release from bronchial epithelial cells by neutrophil defensins. Am J Physiol Lung Cell Mol Physiol (2000) 1.08
2010: the year of the lung. Eur Respir J (2011) 1.07
The protective effect of low-dose inhaled fenoterol against methacholine and exercise-induced bronchoconstriction in asthma: a dose-response study. J Allergy Clin Immunol (1992) 1.07
Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair. Br J Dermatol (2012) 1.07
Persistency of response to omalizumab therapy in severe allergic (IgE-mediated) asthma. Allergy (2011) 1.07
Mechanisms of cell death induced by the neutrophil antimicrobial peptides alpha-defensins and LL-37. Inflamm Res (2006) 1.06
Combination therapy for chronic obstructive pulmonary disease: one size fits all? Eur Respir J (2003) 1.06
L-Pyroglutamyl-L-prolyl-L-valine-p-nitroanilide, a highly specific substrate for granulocyte elastase. Scand J Clin Lab Invest (1983) 1.05
How stress gets under the skin: cortisol and stress reactivity in psoriasis. Br J Dermatol (2010) 1.05
TNF-alpha and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway. Arch Dermatol Res (2000) 1.05
Bacterial degradation of cyclohexane. Participation of a co-oxidation reaction. Antonie Van Leeuwenhoek (1974) 1.05
The complement subcomponent C1q mediates binding of immune complexes and aggregates to endothelial cells in vitro. Eur J Immunol (1988) 1.04
Role of YadA in resistance to killing of Yersinia enterocolitica by antimicrobial polypeptides of human granulocytes. Infect Immun (1996) 1.04
Increased number of B-cells in bronchial biopsies in COPD. Eur Respir J (2006) 1.04
Impaired perception of dyspnea in patients with severe asthma. Relation to sputum eosinophils. Am J Respir Crit Care Med (1998) 1.03
Induction of normal and psoriatic phenotypes in submerged keratinocyte cultures. J Cell Physiol (1996) 1.03
Asthma severity and susceptibility to air pollution. Eur Respir J (1998) 1.02
A rare cause of Ortner's syndrome (cardiovocal hoarseness). Thorax (2004) 1.02
Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection. J Allergy Clin Immunol (2001) 1.02
Differential expression of SKALP/Elafin in human epidermal tumors. Am J Pathol (1993) 1.01