Published in Proc Natl Acad Sci U S A on September 12, 2000
Monitoring of heparin and its low-molecular-weight analogs by silicon field effect. Proc Natl Acad Sci U S A (2006) 1.45
Cleavage of the antithrombin III binding site in heparin by heparinases and its implication in the generation of low molecular weight heparin. Proc Natl Acad Sci U S A (2000) 1.27
Top-down approach for the direct characterization of low molecular weight heparins using LC-FT-MS. Anal Chem (2012) 1.26
Heparin mapping using heparin lyases and the generation of a novel low molecular weight heparin. J Med Chem (2010) 1.24
Heparan sulfate phage display antibodies identify distinct epitopes with complex binding characteristics: insights into protein binding specificities. J Biol Chem (2009) 1.05
Rational design of low-molecular weight heparins with improved in vivo activity. Proc Natl Acad Sci U S A (2003) 1.04
Heparin sequencing brings structure to the function of complex oligosaccharides. Proc Natl Acad Sci U S A (2000) 1.00
Scientific considerations in the review and approval of generic enoxaparin in the United States. Nat Biotechnol (2013) 0.97
Cross-talk of anosmin-1, the protein implicated in X-linked Kallmann's syndrome, with heparan sulphate and urokinase-type plasminogen activator. Biochem J (2004) 0.90
Harnessing glycomics technologies: integrating structure with function for glycan characterization. Electrophoresis (2012) 0.89
Therapeutically targeting protein-glycan interactions. Br J Pharmacol (2009) 0.88
A computational approach for deciphering the organization of glycosaminoglycans. PLoS One (2010) 0.81
Solid-phase synthesis of alpha-glucosamine sulfoforms with fragmentation analysis by tandem mass spectrometry. J Org Chem (2008) 0.80
Discovery of a heparan sulfate 3-O-sulfation specific peeling reaction. Anal Chem (2014) 0.77
Analysis of Glycosaminoglycans Using Mass Spectrometry. Curr Proteomics (2015) 0.76
Glycomics approaches for the bioassay and structural analysis of heparin/heparan sulphates. Metabolites (2012) 0.76
An integrated approach using orthogonal analytical techniques to characterize heparan sulfate structure. Glycoconj J (2016) 0.75
Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. Biomolecules (2013) 0.75
The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila. Nature (1999) 2.22
Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development (1999) 1.86
Sequencing complex polysaccharides. Science (1999) 1.85
Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. Development (1997) 1.74
Examination of the substrate specificity of heparin and heparan sulfate lyases. Biochemistry (1990) 1.60
Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin. EMBO J (1999) 1.38
Mechanism of heparin activation of antithrombin. Role of individual residues of the pentasaccharide activating sequence in the recognition of native and activated states of antithrombin. J Biol Chem (1998) 1.34
Utility of non-covalent complexes in the matrix-assisted laser desorption ionization mass spectrometry of heparin-derived oligosaccharides. Carbohydr Res (1995) 1.29
Cleavage of the antithrombin III binding site in heparin by heparinases and its implication in the generation of low molecular weight heparin. Proc Natl Acad Sci U S A (2000) 1.27
Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth. Eur J Biochem (1999) 1.27
A strategy for rapid sequencing of heparan sulfate and heparin saccharides. Proc Natl Acad Sci U S A (1999) 1.27
Mass spectrometric molecular-weight determination of highly acidic compounds of biological significance via their complexes with basic polypeptides. Proc Natl Acad Sci U S A (1994) 1.26
Direct evidence for a predominantly exolytic processive mechanism for depolymerization of heparin-like glycosaminoglycans by heparinase I. Proc Natl Acad Sci U S A (1998) 1.23
Mass spectrometric and capillary electrophoretic investigation of the enzymatic degradation of heparin-like glycosaminoglycans. Proc Natl Acad Sci U S A (1998) 1.22
Heparinase inhibits neovascularization. Proc Natl Acad Sci U S A (1994) 1.19
Mass spectrometric evidence for the enzymatic mechanism of the depolymerization of heparin-like glycosaminoglycans by heparinase II. Proc Natl Acad Sci U S A (1998) 1.04
Enzymatic preparation of heparin oligosaccharides containing antithrombin III binding sites. J Biol Chem (1996) 1.02
Characterization of fibroblast growth factor 1 binding heparan sulfate domain. Glycobiology (1999) 0.96
Common binding sites for beta-amyloid fibrils and fibroblast growth factor-2 in heparan sulfate from human cerebral cortex. J Biol Chem (1999) 0.95
Preparation and biological activity of N-sulfonated chondroitin and dermatan sulfate derivatives. Carbohydr Res (1996) 0.91
Oligosaccharide sequence of human breast cancer cell heparan sulfate with high affinity for laminin. J Biol Chem (1998) 0.81
Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog. Science (2000) 5.91
n-Tetradecanoyl is the NH2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle. Proc Natl Acad Sci U S A (1982) 4.51
Amino acid sequence of bacteriorhodopsin. Proc Natl Acad Sci U S A (1979) 3.74
Giant cell arteritis: validity and reliability of various diagnostic criteria. Am J Ophthalmol (1997) 3.31
Rat hepatic cytosolic phosphoenolpyruvate carboxykinase (GTP). Structures of the protein, messenger RNA, and gene. J Biol Chem (1985) 2.82
Risk factors for diabetic retinopathy in self-reported rural population with diabetes. J Postgrad Med (2009) 2.67
Appendix 5. Nomenclature for peptide fragment ions (positive ions). Methods Enzymol (1990) 2.41
Primary structure of the Streptomyces enzyme endo-beta-N-acetylglucosaminidase H. J Biol Chem (1984) 2.40
Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin. Chem Biol (1997) 2.38
Overnight calls in primary care: randomised controlled trial of management using nurse telephone consultation. BMJ (1999) 2.32
Medical therapy of rhinosporidiosis with dapsone. J Laryngol Otol (1993) 2.29
Enzymatic degradation of glycosaminoglycans. Crit Rev Biochem Mol Biol (1995) 2.21
Partial primary structure of bacteriorhodopsin: sequencing methods for membrane proteins. Proc Natl Acad Sci U S A (1979) 2.17
Hydroxyarginine-containing polyphenolic proteins in the adhesive plaques of the marine mussel Mytilus edulis. J Biol Chem (1995) 2.16
Sequencing of peptides by tandem mass spectrometry and high-energy collision-induced dissociation. Methods Enzymol (1990) 2.14
Phenethyl alcohol and tryptophol: autoantibiotics produced by the fungus Candida albicans. Science (1969) 2.13
Medical decision-making capacity in patients with mild cognitive impairment. Neurology (2007) 2.11
Novel fragmentation process of peptides by collision-induced decomposition in a tandem mass spectrometer: differentiation of leucine and isoleucine. Anal Chem (1987) 2.10
Prospective reliability of the STRokE DOC wireless/site independent telemedicine system. Neurology (2005) 2.08
Water pollution: organic compounds in the Charles River, Boston. Science (1972) 2.01
Cost analysis of nurse telephone consultation in out of hours primary care: evidence from a randomised controlled trial. BMJ (2000) 1.99
Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents. J Clin Invest (1998) 1.97
Characterization by tandem mass spectrometry of structural modifications in proteins. Science (1987) 1.94
Primary structure of a large aminoacyl-tRNA synthetase. Science (1981) 1.93
14C activity and global carbon cycle changes over the past 50,000 years. Science (2004) 1.91
Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease. Arch Biochem Biophys (1993) 1.90
Sequencing complex polysaccharides. Science (1999) 1.85
An overview of the CERC ARTEMIS project. Proc Annu Symp Comput Appl Med Care (1995) 1.80
Conformational changes and anticoagulant activity of chondroitin sulfate following its O-sulfonation. Carbohydr Res (1998) 1.79
Heparin and heparan sulfate: biosynthesis, structure and function. Curr Opin Chem Biol (2000) 1.75
Decreased color discrimination and contrast sensitivity in Parkinson's disease. J Neurol Sci (2000) 1.75
Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. Development (1997) 1.74
Treatment consent capacity in patients with traumatic brain injury across a range of injury severity. Neurology (2012) 1.60
Biliary diversion by use of the appendix (cholecystoappendicostomy) in progressive familial intrahepatic cholestasis. J Pediatr Gastroenterol Nutr (1999) 1.55
Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics. Neurology (2002) 1.54
Histological assessment of intermediate- and long-term creatine monohydrate supplementation in mice and rats. Am J Physiol Regul Integr Comp Physiol (2003) 1.54
Primary structure of histidine-tRNA synthetase and characterization of hisS transcripts. J Biol Chem (1985) 1.53
Genetic diagnosis in Lafora disease: genotype-phenotype correlations and diagnostic pitfalls. Neurology (2007) 1.53
Cell surface glypicans are low-affinity endostatin receptors. Mol Cell (2001) 1.51
Congenital absence of incus and head of stapes. Arch Otolaryngol Head Neck Surg (1987) 1.48
Animal model of posthypoxic myoclonus: effects of serotonergic antagonists. Neurology (1999) 1.47
Diagnostic value of tissue polypeptide-specific antigen (TPS) in neuroblastoma and Wilms' tumour. Br J Cancer (1998) 1.46
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3A sulfates N-unsubstituted glucosamine residues. J Biol Chem (1999) 1.45
Strategy for the mass spectrometric verification and correction of the primary structures of proteins deduced from their DNA sequences. Proc Natl Acad Sci U S A (1984) 1.41
Structure elucidation of dinucleotides by mass spectrometry. Biochem Biophys Res Commun (1968) 1.40
Escherichia coli glutaminyl-tRNA synthetase. II. Characterization of the glnS gene product. J Biol Chem (1982) 1.40
Living with a depressed person. J Consult Clin Psychol (1987) 1.40
Peptidoglycans as promoters of slow-wave sleep. II. Somnogenic and pyrogenic activities of some naturally occurring muramyl peptides; correlations with mass spectrometric structure determination. J Biol Chem (1984) 1.39
A survey of resuscitation training in Canadian undergraduate medical programs. CMAJ (1992) 1.39
Cognitive models of medical decision-making capacity in patients with mild cognitive impairment. J Int Neuropsychol Soc (2008) 1.38
Glutamyl-tRNA synthetase of Escherichia coli. Isolation and primary structure of the gltX gene and homology with other aminoacyl-tRNA synthetases. J Biol Chem (1986) 1.35
Percutaneous A1 pulley release: a cadaveric study. J Hand Surg Am (1995) 1.34
Primary structures of both subunits of Escherichia coli glycyl-tRNA synthetase. J Biol Chem (1983) 1.32
Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells. Chem Biol (1999) 1.32
Utility of non-covalent complexes in the matrix-assisted laser desorption ionization mass spectrometry of heparin-derived oligosaccharides. Carbohydr Res (1995) 1.29
A21978C, a complex of new acidic peptide antibiotics: isolation, chemistry, and mass spectral structure elucidation. J Antibiot (Tokyo) (1987) 1.29
Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevance. Radiology (1992) 1.28
Cleavage of the antithrombin III binding site in heparin by heparinases and its implication in the generation of low molecular weight heparin. Proc Natl Acad Sci U S A (2000) 1.27
Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry (2001) 1.26
Mass spectrometric molecular-weight determination of highly acidic compounds of biological significance via their complexes with basic polypeptides. Proc Natl Acad Sci U S A (1994) 1.26
Medical decision-making capacity in mild cognitive impairment: a 3-year longitudinal study. Neurology (2008) 1.25
Induction of orientation of bacterial cellulose microfibrils by a novel terpenoid from Acetobacter xylinum. Biochem J (1973) 1.24
Rabbit muscle creatine phosphokinase. CDNA cloning, primary structure and detection of human homologues. J Biol Chem (1984) 1.24
6-O-sulfotransferase-1 represents a critical enzyme in the anticoagulant heparan sulfate biosynthetic pathway. J Biol Chem (2001) 1.23
Direct evidence for a predominantly exolytic processive mechanism for depolymerization of heparin-like glycosaminoglycans by heparinase I. Proc Natl Acad Sci U S A (1998) 1.23
Mass spectrometric and capillary electrophoretic investigation of the enzymatic degradation of heparin-like glycosaminoglycans. Proc Natl Acad Sci U S A (1998) 1.22
Surface-active novel glycolipid and linked 3-hydroxy fatty acids produced by Serratia rubidaea. J Bacteriol (1990) 1.21
Sulfur-containing nucleoside from yeast transfer ribonucleic acid: 2-thio-5(or 6)-uridine acetic acid methyl ester. Science (1968) 1.20
Carbenicillin and penicillin G inhibit platelet function in vitro by impairing the interaction of agonists with the platelet surface. J Clin Invest (1980) 1.20
Malformin C, a new metabolite of Aspergillus niger. J Am Chem Soc (1976) 1.19
Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes. J Biol Chem (1997) 1.19
Experiences with ARTEMIS--an Internet-based telemedicine system. Proc AMIA Annu Fall Symp (1997) 1.18
Is neuronal dysfunction an early sign of diabetic retinopathy? Microperimetry and spectral domain optical coherence tomography (SD-OCT) study in individuals with diabetes, but no diabetic retinopathy. Eye (Lond) (2009) 1.17
Heterotopia of the tonsil. J Laryngol Otol (1996) 1.17
Prospective longitudinal assessment of hallucinations in Parkinson's disease. Neurology (2001) 1.16
Evaluation of a multicenter ethics objective structured clinical examination. J Gen Intern Med (1994) 1.16
Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition. J Biol Chem (2000) 1.16
Developing a standard short questionnaire for the assessment of patient satisfaction with out-of-hours primary care. Fam Pract (2005) 1.16
Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines. J Clin Endocrinol Metab (1997) 1.16
Reviewing emergency care systems I: insights from system dynamics modelling. Emerg Med J (2004) 1.15
Characterization of the glycosylation sites in yeast external invertase. I. N-linked oligosaccharide content of the individual sequons. J Biol Chem (1988) 1.15
Fast atom bombardment mass spectrometry and tandem mass spectrometry of biologically active peptidoglycan monomers from Neisseria gonorrhoeae. J Biol Chem (1987) 1.15
Proximal tubular basement membrane width in insulin-dependent diabetes mellitus. Kidney Int (1998) 1.15
The amino acid sequence of a carboxypeptidase inhibitor from potatoes. Biochemistry (1975) 1.14
Glycine decarboxylase: protein chemistry and molecular biology of the major protein in leaf mitochondria. J Bioenerg Biomembr (1995) 1.14
A pilot survey of African-American physician perceptions about clinical trials. J Natl Med Assoc (2001) 1.14
Peptidoglycans as promoters of slow-wave sleep. I. Structure of the sleep-promoting factor isolated from human urine. J Biol Chem (1984) 1.13
Should cotton buds be banned? Trop Doct (1997) 1.13
On the regulation of fibroblast growth factor activity by heparin-like glycosaminoglycans. Angiogenesis (1997) 1.12
Objective changes in motor function during placebo treatment in PD. Neurology (2000) 1.12
Cerebral processes related to visuomotor imagery and generation of simple finger movements studied with positron emission tomography. Neuroimage (1998) 1.12