J L Tilly

Author PubWeight™ 69.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A sperm ion channel required for sperm motility and male fertility. Nature 2001 4.43
2 Defects in regulation of apoptosis in caspase-2-deficient mice. Genes Dev 1998 3.24
3 Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. Nat Med 2000 2.96
4 Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals. Nat Genet 2001 2.79
5 Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nat Med 1997 2.19
6 Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency. Nat Genet 1999 1.64
7 A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor. J Clin Invest 1996 1.57
8 Oocyte apoptosis: like sand through an hourglass. Dev Biol 1999 1.46
9 Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the post-natal female mouse gonad. Endocrinology 1995 1.45
10 Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats. Toxicol Appl Pharmacol 1996 1.39
11 Caspase-3 gene knockout defines cell lineage specificity for programmed cell death signaling in the ovary. Endocrinology 2001 1.22
12 Hormonal control of apoptotic cell death in the testis: gonadotropins and androgens as testicular cell survival factors. Mol Endocrinol 1993 1.15
13 Enhanced expression of bax in small preantral follicles during 4-vinylcyclohexene diepoxide-induced ovotoxicity in the rat. Toxicol Appl Pharmacol 1996 1.15
14 Targeted expression of Bcl-2 in mouse oocytes inhibits ovarian follicle atresia and prevents spontaneous and chemotherapy-induced oocyte apoptosis in vitro. Mol Endocrinol 1999 1.13
15 Gonadotropin suppression of apoptosis in cultured preovulatory follicles: mediatory role of endogenous insulin-like growth factor I. Endocrinology 1994 1.07
16 The aryl hydrocarbon receptor, a basic helix-loop-helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse. Endocrinology 2000 1.04
17 Fragmentation and death (a.k.a. apoptosis) of ovulated oocytes. Mol Hum Reprod 1999 1.03
18 Mitochondria and the death of oocytes. Nature 2000 1.03
19 Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: a unique model of apoptosis within a syncytium. Placenta 2000 1.00
20 Germ cell apoptosis after treatment of cryptorchidism with human chorionic gonadotropin is associated with impaired reproductive function in the adult. J Clin Invest 1997 1.00
21 Analysis of apoptosis and expression of bcl-2 gene family members in the human and baboon ovary. Cell Death Differ 1998 0.97
22 Lobe-specific apoptotic cell death in rat prostate after androgen ablation by castration. Endocrinology 1995 0.96
23 Gonadotropin-induced up- and down-regulation of ovarian follicle-stimulating hormone (FSH) receptor gene expression in immature rats: effects of pregnant mare's serum gonadotropin, human chorionic gonadotropin, and recombinant FSH. Endocrinology 1992 0.95
24 Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure. Cell Death Differ 2006 0.95
25 Segregation of retinoic acid effects on fetal ovarian germ cell mitosis versus apoptosis by requirement for new macromolecular synthesis. Endocrinology 1999 0.93
26 Identification of potassium-dependent and -independent components of the apoptotic machinery in mouse ovarian germ cells and granulosa cells. Biol Reprod 2000 0.91
27 Overexpression of bcl-xL protects astrocytes from glucose deprivation and is associated with higher glutathione, ferritin, and iron levels. Anesthesiology 1999 0.91
28 Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line, LNCaP. Endocrinology 1996 0.90
29 Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function. Cell Death Differ 2001 0.89
30 Sphingolipid regulation of female gonadal cell apoptosis. Ann N Y Acad Sci 2000 0.89
31 Programmed cell death in the ovary: insights and future prospects using genetic technologies. Mol Endocrinol 2001 0.88
32 Localization, regulation and possible consequences of apoptotic protease-activating factor-1 (Apaf-1) expression in granulosa cells of the mouse ovary. Endocrinology 1999 0.88
33 Caspase-12 compensates for lack of caspase-2 and caspase-3 in female germ cells. Apoptosis 2007 0.88
34 Niemann-Pick Disease versus acid sphingomyelinase deficiency. Cell Death Differ 2001 0.88
35 Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle. Endocrinology 1995 0.87
36 Requirement for phosphatidylinositol-3'-kinase in cytokine-mediated germ cell survival during fetal oogenesis in the mouse. Endocrinology 1999 0.87
37 Detection of apoptosis in human and rat ovarian follicles. J Soc Gynecol Investig 1998 0.86
38 Differential expression of members of the bcl-2 gene family in proliferative and secretory human endometrium: glandular epithelial cell apoptosis is associated with increased expression of bax. J Clin Endocrinol Metab 1997 0.86
39 Follicle-stimulating hormone receptor expression in the rat ovary: increases during prepubertal development and regulation by the opposing actions of transforming growth factors beta and alpha. Biol Reprod 1994 0.86
40 Cleavage of cytoskeletal proteins by caspases during ovarian cell death: evidence that cell-free systems do not always mimic apoptotic events in intact cells. Cell Death Differ 1997 0.86
41 Cumulus cells are required for the increased apoptotic potential in oocytes of aged mice. Hum Reprod 1997 0.84
42 Susceptibility of avian ovarian granulosa cells to apoptosis is dependent upon stage of follicle development and is related to endogenous levels of bcl-xlong gene expression. Endocrinology 1996 0.84
43 Ultrastructure of excitotoxic neuronal death in murine cortical culture. Brain Res 1995 0.83
44 Induction of PreB cell apoptosis by 7,12-dimethylbenz[a]anthracene in long-term primary murine bone marrow cultures. Toxicol Appl Pharmacol 1997 0.83
45 Increased bax and interleukin-1beta-converting enzyme messenger ribonucleic acid levels coincide with apoptosis in the bovine corpus luteum during structural regression. Biol Reprod 1997 0.83
46 Realizing the promise of apoptosis-based therapies: separating the living from the clinically undead. Cell Death Differ 2003 0.82
47 Estradiol-mediated suppression of apoptosis in the rabbit corpus luteum is associated with a shift in expression of bcl-2 family members favoring cellular survival. Biol Reprod 1998 0.82
48 Apoptotic cell death in the rat adrenal gland: an in vivo and in vitro investigation. Cell Tissue Res 1996 0.81
49 Regulated expression and potential roles of p53 and Wilms' tumor suppressor gene (WT1) during follicular development in the human ovary. J Clin Endocrinol Metab 2000 0.81
50 Caffeine potentiates the lethality of tumour necrosis factor in cancer cells. Br J Cancer 1993 0.80
51 Effects of vasoactive intestinal peptide on steroid secretion and plasminogen activator activity in granulosa cells of the hen. Biol Reprod 1988 0.80
52 Accumulation of caspase-3 messenger ribonucleic acid and induction of caspase activity in the ovine corpus luteum following prostaglandin F2alpha treatment in vivo. Biol Reprod 1999 0.79
53 Apoptosis and the ovary: a fashionable trend or food for thought? Fertil Steril 1997 0.79
54 Expression of superoxide dismutase, catalase and glutathione peroxidase in the bovine corpus luteum: evidence supporting a role for oxidative stress in luteolysis. Endocrine 1995 0.79
55 Antioxidants mimic the ability of chorionic gonadotropin to suppress apoptosis in the rabbit corpus luteum in vitro: a novel role for superoxide dismutase in regulating bax expression. Endocrinology 1999 0.78
56 Physiological cell death in endocrine-dependent tissues: an ovarian perspective. Clin Endocrinol (Oxf) 1997 0.78
57 Cytochrome P450 side-chain cleavage (P450scc) in the hen ovary. I. Regulation of P450scc messenger RNA levels and steroidogenesis in theca cells of developing follicles. Biol Reprod 1991 0.77
58 Vasoactive intestinal peptide-mediated suppression of apoptosis in the ovary: potential mechanisms of action and evidence of a conserved antiatretogenic role through evolution. Endocrinology 1995 0.77
59 High and low molecular weight DNA cleavage in ovarian granulosa cells: characterization and protease modulation in intact cells and in cell-free nuclear autodigestion assays. Cell Death Differ 1998 0.77
60 Role of calcium in the regulation of theca cell androstenedione production in the domestic hen. J Reprod Fertil 1991 0.76
61 Biphasic developmental expression of adrenocorticotropin receptor messenger ribonucleic acid levels in the baboon fetal adrenal gland. Endocrinology 1996 0.76
62 Elevated expression of the proapoptotic BCL-2 family member, BAK, in the human endometrium coincident with apoptosis during the secretory phase of the cycle. Fertil Steril 1998 0.75
63 Second messenger pathways mediating chicken luteinizing hormone secretion from dispersed pituitary cells. Biol Reprod 1991 0.75
64 Isolation of turkey adrenocortical cell angiotensin II (AII) receptor partial cDNA: evidence for a single-copy gene expressed predominantly in the adrenal gland. Biochem Biophys Res Commun 1993 0.75
65 Hormonal modulation of apoptosis in the rat adrenal gland in vitro is dependent on structural integrity. Endocrine 1997 0.75
66 Expression of bcl-2 and nr-13 in hen ovarian follicles during development. Biol Reprod 1997 0.75
67 Evidence that arachidonic acid influences hen granulosa cell steroidogenesis and plasminogen activator activity by a protein kinase C-independent mechanism. Biol Reprod 1990 0.75
68 Inhibition of nitric oxide synthesis potentiates apoptosis in the rabbit corpus luteum. Reprod Biomed Online 2004 0.75
69 Models to elucidate the regulation of adrenal cell death. Endocr Res 1999 0.75
70 Expression of the p53 and Wilms' tumor suppressor genes in the rat ovary: gonadotropin repression in vivo and immunohistochemical localization of nuclear p53 protein to apoptotic granulosa cells of atretic follicles. Endocrinology 1995 0.75
71 Possible role for arachidonic acid in the control of steroidogenesis in hen theca. Biol Reprod 1991 0.75
72 Role of apoptosis in functional luteolysis in the pregnant rabbit corpus luteum: evidence of a role for placental-derived factors in promoting luteal cell survival. Apoptosis 2004 0.75
73 Genomic plasticity in cell death susceptibility. Cell Death Differ 2002 0.75
74 Arachidonic acid inhibits luteinizing hormone-stimulated progesterone production in hen granulosa cells. Biol Reprod 1990 0.75