Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy.

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Published in Nat Med on October 01, 2000

Authors

Y Morita1, G I Perez, F Paris, S R Miranda, D Ehleiter, A Haimovitz-Friedman, Z Fuks, Z Xie, J C Reed, E H Schuchman, R N Kolesnick, J L Tilly

Author Affiliations

1: Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts 02114, USA.

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