Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events.
|
Biophys J
|
1996
|
7.66
|
2
|
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.
|
Genes Dev
|
1994
|
5.90
|
3
|
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons.
|
Cell
|
1993
|
5.12
|
4
|
Maximum likelihood estimation of aggregated Markov processes.
|
Proc Biol Sci
|
1997
|
4.96
|
5
|
Mapping the conformational wave of acetylcholine receptor channel gating.
|
Nature
|
2000
|
4.00
|
6
|
A direct optimization approach to hidden Markov modeling for single channel kinetics.
|
Biophys J
|
2000
|
3.54
|
7
|
Essential role of Mash-2 in extraembryonic development.
|
Nature
|
1994
|
3.36
|
8
|
Flickering of a nicotinic ion channel to a subconductance state.
|
Biophys J
|
1983
|
2.92
|
9
|
Does curare affect transmitter release?
|
J Physiol
|
1971
|
2.80
|
10
|
Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity.
|
Neuron
|
1995
|
2.55
|
11
|
A re-examination of adult mouse nicotinic acetylcholine receptor channel activation kinetics.
|
J Physiol
|
1999
|
2.49
|
12
|
Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia.
|
Nat Genet
|
1996
|
2.32
|
13
|
Non-injection methods for the production of embryonic stem cell-embryo chimaeras.
|
Nature
|
1993
|
2.27
|
14
|
Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation.
|
J Gen Physiol
|
1997
|
2.25
|
15
|
Hidden Markov modeling for single channel kinetics with filtering and correlated noise.
|
Biophys J
|
2000
|
2.25
|
16
|
Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
|
Hum Mol Genet
|
1999
|
2.20
|
17
|
Single-channel currents from acetylcholine receptors in embryonic chick muscle. Kinetic and conductance properties of gaps within bursts.
|
Biophys J
|
1984
|
2.06
|
18
|
Therapist success and its determinants.
|
Arch Gen Psychiatry
|
1985
|
2.00
|
19
|
The dissociation of acetylcholine from open nicotinic receptor channels.
|
Proc Natl Acad Sci U S A
|
2001
|
1.91
|
20
|
Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist.
|
J Gen Physiol
|
2000
|
1.83
|
21
|
Inorganic, monovalent cations compete with agonists for the transmitter binding site of nicotinic acetylcholine receptors.
|
Biophys J
|
1996
|
1.82
|
22
|
Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: a single-channel study of second transmembrane segment 12' mutants.
|
J Gen Physiol
|
2000
|
1.75
|
23
|
Activation of recombinant mouse acetylcholine receptors by acetylcholine, carbamylcholine and tetramethylammonium.
|
J Physiol
|
1995
|
1.74
|
24
|
The extracellular linker of muscle acetylcholine receptor channels is a gating control element.
|
J Gen Physiol
|
2000
|
1.74
|
25
|
Heterogeneous kinetic properties of acetylcholine receptor channels in Xenopus myocytes.
|
J Physiol
|
1986
|
1.73
|
26
|
Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes.
|
Proc Natl Acad Sci U S A
|
1999
|
1.68
|
27
|
Identification of a high affinity divalent cation binding site near the entrance of the NMDA receptor channel.
|
Neuron
|
1996
|
1.56
|
28
|
Binding sites contribute unequally to the gating of mouse nicotinic alpha D200N acetylcholine receptors.
|
J Physiol
|
1996
|
1.53
|
29
|
Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.
|
Hum Mol Genet
|
2000
|
1.45
|
30
|
Rare primary CNS anaplastic large cell lymphoma in an immunocompetent adult: a clinical-pathologic case report and review case of the literature.
|
Clin Neuropathol
|
2006
|
1.43
|
31
|
A mutational analysis of the acetylcholine receptor channel transmitter binding site.
|
Biophys J
|
1999
|
1.42
|
32
|
Activation kinetics of recombinant mouse nicotinic acetylcholine receptors: mutations of alpha-subunit tyrosine 190 affect both binding and gating.
|
Biophys J
|
1995
|
1.34
|
33
|
Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns.
|
J Gen Physiol
|
1997
|
1.34
|
34
|
Single-channel electrophysiology: use of the patch clamp.
|
Methods Enzymol
|
1983
|
1.28
|
35
|
Patch clamp studies of single ionic channels.
|
Annu Rev Biophys Bioeng
|
1984
|
1.24
|
36
|
Activation of muscle nicotinic acetylcholine receptor channels by nicotinic and muscarinic agonists.
|
Br J Pharmacol
|
1999
|
1.18
|
37
|
A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice.
|
Genetics
|
1995
|
1.14
|
38
|
Human umbilical cord blood: a clinically useful source of transplantable hematopoietic stem/progenitor cells.
|
Int J Cell Cloning
|
1990
|
1.05
|
39
|
The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxiety.
|
Proc Natl Acad Sci U S A
|
2010
|
1.00
|
40
|
Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence.
|
J Gen Physiol
|
1997
|
0.97
|
41
|
Drosophila engrailed can substitute for mouse Engrailed1 function in mid-hindbrain, but not limb development.
|
Development
|
1998
|
0.96
|
42
|
Na(+) occupancy and Mg(2+) block of the n-methyl-d-aspartate receptor channel.
|
J Gen Physiol
|
2001
|
0.94
|
43
|
A distinct contribution of the delta subunit to acetylcholine receptor channel activation revealed by mutations of the M2 segment.
|
Biophys J
|
1998
|
0.93
|
44
|
On what bases do patients choose their therapists?
|
J Psychother Pract Res
|
1993
|
0.92
|
45
|
The nature of cation-pi binding: interactions between tetramethylammonium ion and benzene in aqueous solution.
|
Biophys J
|
1993
|
0.92
|
46
|
LSP1 modulates leukocyte populations in resting and inflamed peritoneum.
|
Blood
|
2000
|
0.92
|
47
|
K(+) occupancy of the N-methyl-d-aspartate receptor channel probed by Mg(2+) block.
|
J Gen Physiol
|
2001
|
0.90
|
48
|
Predicting the outcome of psychotherapy. findings of the Penn Psychotherapy Project.
|
Arch Gen Psychiatry
|
1980
|
0.89
|
49
|
Correlation of agonist structure with acetylcholine receptor kinetics: studies on the frog end-plate and on chick embryo muscle.
|
J Physiol
|
1983
|
0.86
|
50
|
Comparison of excitatory currents activated by different transmitters on crustacean muscle. I. Acetylcholine-activated channels.
|
J Gen Physiol
|
1983
|
0.85
|
51
|
Transplantation of umbilical cord blood in Fanconi's anemia.
|
Nouv Rev Fr Hematol
|
1990
|
0.84
|
52
|
Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux.
|
Urology
|
2001
|
0.82
|
53
|
Targeted inactivation of the mouse Huntington's disease gene homolog Hdh.
|
Cold Spring Harb Symp Quant Biol
|
1996
|
0.80
|
54
|
LPROC: a software tool for analysing single-channel data.
|
P R Health Sci J
|
1988
|
0.79
|
55
|
The gene trap approach in embryonic stem cells: the potential for genetic screens in mice.
|
Ciba Found Symp
|
1992
|
0.79
|
56
|
Comparison of excitatory currents activated by different transmitters on crustacean muscle. II. Glutamate-activated currents and comparison with acetylcholine currents present on the same muscle.
|
J Gen Physiol
|
1983
|
0.78
|
57
|
Temperature measurement and control of small volumes: applications for single channel recording.
|
Methods Enzymol
|
1986
|
0.78
|
58
|
The double-blind design: a theoretical re-examination.
|
Can Med Assoc J
|
1967
|
0.75
|
59
|
Facts on the Economic Recovery Tax Act of 1981 for speech-language pathologists and audiologists.
|
ASHA
|
1982
|
0.75
|
60
|
A simple cardiac monitoring system.
|
Med J Aust
|
1970
|
0.75
|
61
|
[Lymphocyte blast transformation test in the diagnosis of atopy].
|
Otolaryngol Pol
|
1982
|
0.75
|
62
|
[(3)H]Choline uptake and metabolism in nonsynaptic regions of a crustacean sensory nerve.
|
J Neurochem
|
1981
|
0.75
|
63
|
Allogeneic bone marrow transplants for Fanconi anemia. A preliminary report from the International Bone Marrow Transplant Registry.
|
Bone Marrow Transplant
|
1992
|
0.75
|
64
|
Simple setup for single and differential photoacoustic spectroscopy.
|
Rev Sci Instrum
|
1978
|
0.75
|
65
|
Kinetic properties of NMDA receptors in embryonic Xenopus spinal neurons.
|
J Neurophysiol
|
1995
|
0.75
|
66
|
Living donor kidney transplantation in Estonia.
|
Transplant Proc
|
1996
|
0.75
|
67
|
Atrial-synchronized demand heart pacing.
|
IEEE Trans Biomed Eng
|
1969
|
0.75
|
68
|
Multi-discipline experience: a fresh approach to aid the multi-handicapped child.
|
J Rehabil
|
1975
|
0.75
|
69
|
Automatic control of potential and agonist-induced current across the endplate membrane by drug electrophoresis.
|
J Neurosci Res
|
1982
|
0.75
|
70
|
Fanconi's anemia variant.
|
Blood
|
1985
|
0.75
|