PubRank

B Guiard

Author PubWeight™ 79.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mitochondrial Hsp70/MIM44 complex facilitates protein import. Nature 1994 3.08
2 Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2). EMBO J 1985 2.29
3 The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44. EMBO J 1997 2.28
4 Successive translocation into and out of the mitochondrial matrix: targeting of proteins to the intermembrane space by a bipartite signal peptide. Cell 1987 2.24
5 The ABC transporter Atm1p is required for mitochondrial iron homeostasis. FEBS Lett 1997 2.21
6 Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. Nature 1996 2.03
7 Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space. Cell 1992 1.96
8 Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites. J Cell Biol 1989 1.84
9 Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria. EMBO J 1996 1.74
10 Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J Cell Biol 1993 1.73
11 Membrane protein degradation by AAA proteases in mitochondria: extraction of substrates from either membrane surface. Mol Cell 2000 1.73
12 Tim23 links the inner and outer mitochondrial membranes. Cell 2000 1.68
13 Polypeptides traverse the mitochondrial envelope in an extended state. FEBS Lett 1990 1.60
14 The formation of respiratory chain complexes in mitochondria is under the proteolytic control of the m-AAA protease. EMBO J 1998 1.56
15 Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase. Nature 1999 1.56
16 An internal targeting signal directing proteins into the mitochondrial intermembrane space. Proc Natl Acad Sci U S A 1999 1.45
17 The requirement of matrix ATP for the import of precursor proteins into the mitochondrial matrix and intermembrane space. Eur J Biochem 1994 1.40
18 Membrane potential-driven protein import into mitochondria. The sorting sequence of cytochrome b(2) modulates the deltapsi-dependence of translocation of the matrix-targeting sequence. Mol Biol Cell 2000 1.39
19 Targeting of cytochrome b2 into the mitochondrial intermembrane space: specific recognition of the sorting signal. EMBO J 1993 1.38
20 Two homologous cytochromes b5 in a single cell. Eur J Biochem 1983 1.34
21 Unfolding of preproteins upon import into mitochondria. EMBO J 1998 1.30
22 Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins. EMBO J 1996 1.28
23 Protein folding causes an arrest of preprotein translocation into mitochondria in vivo. J Cell Biol 1991 1.26
24 The delta psi- and Hsp70/MIM44-dependent reaction cycle driving early steps of protein import into mitochondria. EMBO J 1996 1.21
25 The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation. EMBO J 2001 1.20
26 Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1(HAP1) activator binds to the CYB2 upstream activation site UAS1-B2. Mol Cell Biol 1991 1.19
27 Mitochondrial precursor proteins are imported through a hydrophilic membrane environment. Eur J Biochem 1987 1.16
28 The S. Cerevisiae HAP complex, a key regulator of mitochondrial function, coordinates nuclear and mitochondrial gene expression. Comp Funct Genomics 2003 1.16
29 Evidence for an interaction between the CYP1(HAP1) activator and a cellular factor during heme-dependent transcriptional regulation in the yeast Saccharomyces cerevisiae. EMBO J 1993 1.14
30 Characterization of the mitochondrial processing peptidase of Neurospora crassa. J Biol Chem 1994 1.14
31 Energy requirements for unfolding and membrane translocation of precursor proteins during import into mitochondria. J Biol Chem 1990 1.11
32 One nuclear gene controls the removal of transient pre-sequences from two yeast proteins: one encoded by the nuclear the other by the mitochondrial genome. EMBO J 1986 1.08
33 Sorting of D-lactate dehydrogenase to the inner membrane of mitochondria. Analysis of topogenic signal and energetic requirements. J Biol Chem 1998 1.06
34 The "cytochrome b5 fold": structure of a novel protein superfamily. J Mol Biol 1979 1.04
35 The "b5-like" domain from chicken-liver sulfite oxidase: a new case of common ancestral origin with liver cytochrome b5 and bakers' yeast cytochrome b2 core. Eur J Biochem 1977 1.03
36 Targeting of a chemically pure preprotein to mitochondria does not require the addition of a cytosolic signal recognition factor. J Biol Chem 1992 1.03
37 Blocking of in vitro translation of Paramecium messenger RNAs is due to messenger RNA primary structure. Biochimie 1984 1.01
38 Homology between bakers' yeast cytochrome b2 and liver microsomal cytochrome b5. Proc Natl Acad Sci U S A 1974 0.99
39 Substitution of PIM1 protease in mitochondria by Escherichia coli Lon protease. J Biol Chem 1996 0.99
40 The sorting signal of cytochrome b2 promotes early divergence from the general mitochondrial import pathway and restricts the unfoldase activity of matrix Hsp70. EMBO J 1995 0.97
41 CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. II. Missense mutation suggests alternative Zn fingers as discriminating agents of gene control. J Mol Biol 1988 0.95
42 Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response. Mol Psychiatry 2011 0.93
43 Regulation of the CYB2 gene expression: transcriptional co-ordination by the Hap1p, Hap2/3/4/5p and Adr1p transcription factors. Mol Microbiol 2000 0.93
44 A novel intermediate on the import pathway of cytochrome b2 into mitochondria: evidence for conservative sorting. EMBO J 1995 0.91
45 A new Hansenula polymorpha HAP4 homologue which contains only the N-terminal conserved domain of the protein is fully functional in Saccharomyces cerevisiae. Curr Genet 2004 0.90
46 Co-ordinate regulation of lactate metabolism genes in yeast: the role of the lactate permease gene JEN1. Mol Genet Genomics 2001 0.90
47 Amino acid sequence of the 'b5-like' heme-binding domain from chicken sulfite oxidase. Eur J Biochem 1979 0.89
48 More similarity between bakers'yeast L-(+)-lactate dehydrogenase and liver microsomal cytochrome b5. Nature 1975 0.88
49 N-terminal tail export from the mitochondrial matrix. Adherence to the prokaryotic "positive-inside" rule of membrane protein topology. J Biol Chem 1999 0.88
50 Complete amino acid sequence of the heme-binding core in bakers' yeast cytochrome b2 (L-(+)-lactate dehydrogenase). Biochimie 1976 0.88
51 Sorting of cytochrome b2 to the intermembrane space of mitochondria. Kinetic analysis of intermediates demonstrates passage through the matrix. J Biol Chem 1995 0.87
52 Determinants in the presequence of cytochrome b2 for import into mitochondria and for proteolytic processing. Eur J Biochem 1996 0.86
53 NMR analysis of CYP1(HAP1) DNA binding domain-CYC1 upstream activation sequence interactions: recognition of a CGG trinucleotide and of an additional thymine 5 bp downstream by the zinc cluster and the N-terminal extremity of the protein. Nucleic Acids Res 1997 0.86
54 The DNA-binding domain of the yeast Saccharomyces cerevisiae CYP1(HAP1) transcription factor possesses two zinc ions which are complexed in a zinc cluster. Eur J Biochem 1994 0.86
55 The sorting route of cytochrome b2 branches from the general mitochondrial import pathway at the preprotein translocase of the inner membrane. J Biol Chem 1997 0.85
56 Regulation of the Saccharomyces cerevisiae DLD1 gene encoding the mitochondrial protein D-lactate ferricytochrome c oxidoreductase by HAP1 and HAP2/3/4/5. Mol Gen Genet 1999 0.84
57 N-terminal hydrophobic sorting signals of preproteins confer mitochondrial hsp70 independence for import into mitochondria. J Biol Chem 1997 0.83
58 Yeast cytochrome b2 gene: isolation with antibody probes. Biochimie 1984 0.83
59 Some DNA targets of the yeast CYP1 transcriptional activator are functionally asymmetric--evidence of two half-sites with different affinities. Eur J Biochem 1997 0.81
60 Heme-mediated transcriptional control in Kluyveromyces lactis. Curr Genet 2000 0.79
61 1H, 15N resonance assignment and three-dimensional structure of CYP1 (HAP1) DNA-binding domain. J Mol Biol 1996 0.79
62 Baker's yeast flavocytochrome b2 (L-(+)-lactate dehydrogenase). An immunological study of structure and function. Eur J Biochem 1976 0.79
63 Yeast L-lactate dehydrogenase (cytochrome b 2 ). Chemical characterization of the heme-binding core. Eur J Biochem 1973 0.78
64 Surface differences and similarities in two homologous proteins. Cytochrome b5 and cytochrome b2 core. Biochim Biophys Acta 1978 0.77
65 Evidence of an overlap between the two half-sites of UAS1-B/CYC1--a new model for Cyp1p (Hap1p) DNA binding. Eur J Biochem 1998 0.76
66 Phenotypic suppression and nuclear accommodation of the mit- oxi1-V25 mutation in isolated yeast mitochondria. Curr Genet 1987 0.75
67 Bromopyruvate as an affinity label for Baker's yeast flavocytochrome b2. Identification of an active-site cysteine and characterization of some cysteine peptides. Eur J Biochem 1982 0.75
68 Binding of Cibacron blue F3GA to the flavin and NADH sites in cytochrome b5 reductase. Eur J Biochem 1980 0.75
69 Reconstitution of liver NADH: cytochrome b5 oxidoreductase and of Desulfovibvio vulgaris flavodoxin with 1-carba-1-deazaflavin. Eur J Biochem 1982 0.75