Published in EMBO J on September 01, 1997
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. J Cell Biol (2006) 3.87
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell (2012) 2.52
Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J (2004) 2.43
Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J (2003) 1.84
The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane. J Cell Biol (1997) 1.80
Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell (2006) 1.75
Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol (1998) 1.71
A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol (2003) 1.71
Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol (2004) 1.67
Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol (2004) 1.66
Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex. J Cell Biol (2001) 1.65
Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1. Proc Natl Acad Sci U S A (2014) 1.56
Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome. Mol Biol Cell (2005) 1.55
Biogenesis of Tom40, core component of the TOM complex of mitochondria. J Cell Biol (1999) 1.53
Protein import channel of the outer mitochondrial membrane: a highly stable Tom40-Tom22 core structure differentially interacts with preproteins, small tom proteins, and import receptors. Mol Cell Biol (2001) 1.53
Tim50, a novel component of the TIM23 preprotein translocase of mitochondria. EMBO J (2003) 1.46
Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export. Mol Cell Biol (2005) 1.42
Membrane potential-driven protein import into mitochondria. The sorting sequence of cytochrome b(2) modulates the deltapsi-dependence of translocation of the matrix-targeting sequence. Mol Biol Cell (2000) 1.39
MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Mol Biol Cell (2011) 1.37
Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol (2005) 1.34
Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane. Mol Biol Cell (2000) 1.31
Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient. Proc Natl Acad Sci U S A (2011) 1.27
A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria. PLoS Biol (2014) 1.27
Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway. Mol Biol Cell (1999) 1.25
Precursor oxidation by Mia40 and Erv1 promotes vectorial transport of proteins into the mitochondrial intermembrane space. Mol Biol Cell (2007) 1.22
Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J (2003) 1.21
The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation. EMBO J (2001) 1.20
Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria. J Cell Biol (2010) 1.20
Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex. Mol Cell Biol (2002) 1.19
Mitochondrial protein synthesis, import, and assembly. Genetics (2012) 1.17
Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space. Mol Cell Biol (2003) 1.14
Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis. J Biol Chem (2013) 1.12
Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol (2010) 1.11
Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane. Biochem J (1998) 1.09
Quaternary structure of the mitochondrial TIM23 complex reveals dynamic association between Tim23p and other subunits. Mol Biol Cell (2007) 1.08
Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase. Mol Biol Cell (2008) 1.04
MnSOD in oxidative stress response-potential regulation via mitochondrial protein influx. Antioxid Redox Signal (2013) 1.04
A cooperative action of the ATP-dependent import motor complex and the inner membrane potential drives mitochondrial preprotein import. Mol Cell Biol (2006) 1.03
A 1-megadalton translocation complex containing Tic20 and Tic21 mediates chloroplast protein import at the inner envelope membrane. Plant Cell (2009) 1.02
Mitochondrial protein import motor: the ATPase domain of matrix Hsp70 is crucial for binding to Tim44, while the peptide binding domain and the carboxy-terminal segment play a stimulatory role. Mol Cell Biol (2000) 1.01
Domain structure and lipid interaction of recombinant yeast Tim44. Proc Natl Acad Sci U S A (1999) 1.01
The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes. EMBO Rep (2006) 1.00
The J-related segment of tim44 is essential for cell viability: a mutant Tim44 remains in the mitochondrial import site, but inefficiently recruits mtHsp70 and impairs protein translocation. J Cell Biol (1999) 0.98
Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b(2) import pathway. Proc Natl Acad Sci U S A (1999) 0.98
Inner mitochondrial translocase Tim50 interacts with 3β-hydroxysteroid dehydrogenase type 2 to regulate adrenal and gonadal steroidogenesis. J Biol Chem (2011) 0.97
Intrinsic circannual regulation of brown adipose tissue form and function in tune with hibernation. Am J Physiol Endocrinol Metab (2013) 0.97
The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation. Mol Cell Biol (2013) 0.97
Lateral release of proteins from the TOM complex into the outer membrane of mitochondria. EMBO J (2011) 0.95
Self-association and precursor protein binding of Saccharomyces cerevisiae Tom40p, the core component of the protein translocation channel of the mitochondrial outer membrane. Biochem J (2001) 0.93
Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol (2012) 0.91
Mechanisms of protein sorting in mitochondria. Cold Spring Harb Perspect Biol (2012) 0.91
The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases. Mol Cell Biol (2008) 0.89
Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Mol Biol Cell (2010) 0.89
The presequence pathway is involved in protein sorting to the mitochondrial outer membrane. EMBO Rep (2014) 0.87
Tim54p connects inner membrane assembly and proteolytic pathways in the mitochondrion. J Cell Biol (2007) 0.87
Signal recognition initiates reorganization of the presequence translocase during protein import. EMBO J (2013) 0.87
Visualizing active membrane protein complexes by electron cryotomography. Nat Commun (2014) 0.84
Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress. Nucleic Acids Res (2010) 0.84
Role of membrane contact sites in protein import into mitochondria. Protein Sci (2015) 0.84
Chemical cleavage of the overexpressed mitochondrial F1beta precursor with CNBr: a new strategy to construct an import-competent preprotein. Biochem J (1999) 0.83
A computational study of the glycine-rich loop of mitochondrial processing peptidase. PLoS One (2013) 0.82
A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria. Mol Biol Cell (2014) 0.81
The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins. Nat Commun (2016) 0.79
Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix. Mol Cell Biol (2014) 0.78
Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis (2001) 0.78
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders. Nat Commun (2014) 0.77
Role of Tim17 in coupling the import motor to the translocation channel of the mitochondrial presequence translocase. Elife (2017) 0.77
Under conditions of insufficient permeability of VDAC1, external NADH may use the TOM complex channel to cross the outer membrane of Saccharomyces cerevisiae mitochondria. J Bioenerg Biomembr (2001) 0.76
Dissecting the Metabolic Role of Mitochondria during Developmental Leaf Senescence. Plant Physiol (2016) 0.76
Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44. J Biol Chem (2017) 0.75
Overlapping Role of Respiratory Supercomplex Factor Rcf2 and Its N-terminal Homolog Rcf3 in Saccharomyces cerevisiae. J Biol Chem (2016) 0.75
Phosphatidylcholine Affects Inner Membrane Protein Translocases of Mitochondria. J Biol Chem (2016) 0.75
Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo-tomography. EMBO Rep (2017) 0.75
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene (1988) 42.65
Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form. Anal Biochem (1991) 12.68
Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J Biol Chem (1982) 12.07
Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis. Anal Biochem (1994) 7.30
Common principles of protein translocation across membranes. Science (1996) 7.00
Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles. Biochemistry (1974) 6.97
Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria. Nature (1986) 5.58
A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. Cell (1995) 3.57
Transport of proteins into mitochondria: translocational intermediates spanning contact sites between outer and inner membranes. Cell (1985) 3.55
The role of Hsp70 in conferring unidirectionality on protein translocation into mitochondria. Science (1994) 3.26
Isolation of components of the chloroplast protein import machinery. Science (1994) 3.24
Mitochondrial Hsp70/MIM44 complex facilitates protein import. Nature (1994) 3.08
Tom5 functionally links mitochondrial preprotein receptors to the general import pore. Nature (1997) 2.88
A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins. J Cell Biol (1993) 2.61
A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein. EMBO J (1990) 2.56
Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44. J Cell Biol (1994) 2.28
Can Hsp70 proteins act as force-generating motors? Cell (1995) 2.24
A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site. Nature (1989) 2.18
Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences. J Biol Chem (1991) 2.17
MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria. EMBO J (1992) 2.16
Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space. Cell (1992) 1.96
The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids. EMBO J (1993) 1.91
The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process. Cell (1996) 1.88
Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane. Proc Natl Acad Sci U S A (1994) 1.87
Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP. Cell (1997) 1.77
A dynamic model of the mitochondrial protein import machinery. Cell (1992) 1.74
Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J Cell Biol (1993) 1.73
The protein import receptor of mitochondria. Trends Biochem Sci (1995) 1.68
The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system. Cell (1995) 1.63
Topology of IEP110, a component of the chloroplastic protein import machinery present in the inner envelope membrane. EMBO J (1996) 1.56
Dynamic interaction of the protein translocation systems in the inner and outer membranes of yeast mitochondria. EMBO J (1995) 1.54
Mechanisms of protein import across the mitochondrial outer membrane. Trends Cell Biol (1996) 1.49
Disruption of the outer membrane restores protein import to trypsin-treated yeast mitochondria. EMBO J (1987) 1.46
The essential yeast protein MIM44 (encoded by MPI1) is involved in an early step of preprotein translocation across the mitochondrial inner membrane. Mol Cell Biol (1993) 1.43
Protein import into yeast mitochondria: the inner membrane import site protein ISP45 is the MPI1 gene product. EMBO J (1993) 1.31
Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins. EMBO J (1996) 1.28
Mitochondrial GrpE is present in a complex with hsp70 and preproteins in transit across membranes. Mol Cell Biol (1994) 1.27
Characterization of the preprotein translocase of the outer mitochondrial membrane by blue native electrophoresis. Biol Chem (1997) 1.23
The nucleotide exchange factor MGE exerts a key function in the ATP-dependent cycle of mt-Hsp70-Tim44 interaction driving mitochondrial protein import. EMBO J (1996) 1.22
Mitochondrial import of subunit Va of cytochrome c oxidase characterized with yeast mutants. J Biol Chem (1995) 1.18
Functional and biogenetical heterogeneity of the inner membrane of rat-liver mitochondria. Eur J Biochem (1972) 1.12
The mitochondrial protein import machinery. Role of ATP in dissociation of the Hsp70.Mim44 complex. J Biol Chem (1995) 1.07
Mas6p can be cross-linked to an arrested precursor and interacts with other proteins during mitochondrial protein import. J Biol Chem (1993) 1.06
Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane. EMBO J (1997) 1.06
Functional and physical interactions of components of the yeast mitochondrial inner-membrane import machinery (MIM). Eur J Biochem (1995) 1.01
The preprotein translocase of the inner mitochondrial membrane: evolutionary conservation of targeting and assembly of Tim17. J Mol Biol (1996) 0.95
The genome of black cottonwood, Populus trichocarpa (Torr. & Gray). Science (2006) 21.03
Nucleotide sequence of the origin of replication of the Escherichia coli K-12 chromosome. Proc Natl Acad Sci U S A (1979) 5.31
Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins. Nature (1990) 5.12
Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim Biophys Acta (1991) 4.16
454 Pyrosequencing analyses of forest soils reveal an unexpectedly high fungal diversity. New Phytol (2009) 4.04
INTESTINAL OBSTRUCTION DUE TO GALL-STONES: WITH REPORT OF THREE SUCCESSFUL CASES. Ann Surg (1912) 3.84
Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins [see comment]. Nature (1998) 3.77
Mitochondrial protein import. Biochim Biophys Acta (1989) 3.66
The preprotein translocase of the mitochondrial inner membrane: function and evolution. J Mol Biol (1999) 3.57
5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis. Gastroenterology (1987) 3.35
Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res (1994) 3.30
Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci U S A (1985) 3.28
Identification of differentially expressed mRNA species by an improved display technique (DDRT-PCR). Nucleic Acids Res (1993) 3.26
Mitochondrial Hsp70/MIM44 complex facilitates protein import. Nature (1994) 3.08
A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23. Nat Struct Biol (2001) 3.06
A major Pseudomonas aeruginosa clone common to patients and aquatic habitats. Appl Environ Microbiol (1994) 3.02
Apaf-1 is a transcriptional target for E2F and p53. Nat Cell Biol (2001) 2.96
Tom5 functionally links mitochondrial preprotein receptors to the general import pore. Nature (1997) 2.88
Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation. J Biol Chem (1999) 2.86
Origin of replication, oriC, of the Escherichia coli K12 chromosome: genetic mapping and minichromosome replication. Cold Spring Harb Symp Quant Biol (1979) 2.85
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase. Mol Cell Biol (1999) 2.84
Cyclin D1 protein expression and function in human breast cancer. Int J Cancer (1994) 2.81
Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses. Eur J Immunol (1997) 2.77
IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells. J Immunol (1999) 2.73
Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data. Genes Immun (2005) 2.69
Endoscopic mucosal resection of early cancer and high-grade dysplasia in Barrett's esophagus. Gastroenterology (2000) 2.66
A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins. J Cell Biol (1993) 2.61
Mitochondrial protein import: nucleoside triphosphates are involved in conferring import-competence to precursors. Cell (1987) 2.61
Oral budesonide for active Crohn's disease. Canadian Inflammatory Bowel Disease Study Group. N Engl J Med (1994) 2.52
Malignant ameloblastoma or ameloblastic carcinoma. Oral Surg Oral Med Oral Pathol (1984) 2.51
Laparoscopic treatment vs open surgery in the solution of major incisional and abdominal wall hernias with mesh. Surg Endosc (1999) 2.46
Multistep assembly of the protein import channel of the mitochondrial outer membrane. Nat Struct Biol (2001) 2.46
Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms. J Biol Chem (1988) 2.43
Demonstration of antigens related to colonic cancer in the human digestive system. Int J Cancer (1970) 2.35
Transport of F1-ATPase subunit beta into mitochondria depends on both a membrane potential and nucleoside triphosphates. FEBS Lett (1986) 2.33
Erroneous diagnosis of hemorrhage from esophageal varices. Am J Dig Dis (1969) 2.30
The transcriptome of the arbuscular mycorrhizal fungus Glomus intraradices (DAOM 197198) reveals functional tradeoffs in an obligate symbiont. New Phytol (2011) 2.29
Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2). EMBO J (1985) 2.29
Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44. J Cell Biol (1994) 2.28
Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem (2000) 2.26
Lysosomal (vacuolar) proteinases of yeast are essential catalysts for protein degradation, differentiation, and cell survival. J Biol Chem (1989) 2.25
Successive translocation into and out of the mitochondrial matrix: targeting of proteins to the intermembrane space by a bipartite signal peptide. Cell (1987) 2.24
Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol (2000) 2.21
The ABC transporter Atm1p is required for mitochondrial iron homeostasis. FEBS Lett (1997) 2.21
Transport of proteins into mitochondria: a potassium diffusion potential is able to drive the import of ADP/ATP carrier. EMBO J (1985) 2.19
MOM19, an import receptor for mitochondrial precursor proteins. Cell (1989) 2.18
Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences. J Biol Chem (1991) 2.17
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Nature (2000) 2.17
MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria. EMBO J (1992) 2.16
Interventions to promote cancer awareness and early presentation: systematic review. Br J Cancer (2009) 2.14
E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene (1998) 2.12
DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1. J Cell Biol (1994) 2.11
The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release. EMBO J (2000) 2.08
Cortical motor reorganization in akinetic patients with Parkinson's disease: a functional MRI study. Brain (2000) 2.06
Assaying protein import into mitochondria. Methods Cell Biol (2001) 2.04
Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. Nature (1996) 2.03
Distinct steps in the import of ADP/ATP carrier into mitochondria. J Biol Chem (1987) 2.02
The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction. EMBO J (1994) 1.99
In vivo biosynthesis of the vacuolar proteinases A and B in the yeast Saccharomyces cerevisiae. J Biol Chem (1982) 1.98
Subunit IV of yeast cytochrome c oxidase: cloning and nucleotide sequencing of the gene and partial amino acid sequencing of the mature protein. EMBO J (1984) 1.97
Sec8p and Sec15p are components of a plasma membrane-associated 19.5S particle that may function downstream of Sec4p to control exocytosis. J Cell Biol (1992) 1.96
Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space. Cell (1992) 1.96
A mitochondrial import receptor for the ADP/ATP carrier. Cell (1990) 1.95
Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: expression of Moloney murine leukemia virus structural genes via the metallothionein promoter. Mol Cell Biol (1987) 1.94
Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell (1994) 1.93
How do polypeptides cross the mitochondrial membranes? Cell (1990) 1.91
The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70. Cell (1999) 1.91
Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins. Nature (1990) 1.90
Equine connective tissue tumors contain unintegrated bovine papilloma virus DNA. J Virol (1980) 1.90
Mini-chromosomes: plasmids which carry the E. coli replication origin. Mol Gen Genet (1978) 1.90
Origin of replication, oriC, of the Escherichia coli K12 chromosome: nucleotide sequence. Cold Spring Harb Symp Quant Biol (1979) 1.89
Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain. J Cell Biol (1990) 1.86
Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone. Int Immunol (1997) 1.85
Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites. J Cell Biol (1989) 1.84
Analysis of mitochondrial protein import using translocation intermediates and specific antibodies. Methods Cell Biol (1991) 1.81
Antibodies to high molecular weight polypeptides of desmosomes: specific localization of a class of junctional proteins in cells and tissue. Differentiation (1981) 1.77
Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor. J Biol Chem (1985) 1.77
Maturation of vacuolar (lysosomal) enzymes in yeast: proteinase yscA and proteinase yscB are catalysts of the processing and activation event of carboxypeptidase yscY. EMBO J (1987) 1.76
Polyethylene glycol-coated (pegylated) liposomal doxorubicin. Rationale for use in solid tumours. Drugs (1997) 1.76
Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria. EMBO J (1996) 1.74
A dynamic model of the mitochondrial protein import machinery. Cell (1992) 1.74
Membrane protein degradation by AAA proteases in mitochondria: extraction of substrates from either membrane surface. Mol Cell (2000) 1.73
Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J Cell Biol (1993) 1.73
Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells. J Biol Chem (1999) 1.73
Import of ADP/ATP carrier into mitochondria: two receptors act in parallel. J Cell Biol (1990) 1.72
Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol (1998) 1.71
Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer. Cancer Res (1995) 1.68
Tim23 links the inner and outer mitochondrial membranes. Cell (2000) 1.68