Published in Circ Res on November 24, 2000
Ischemia-reperfusion injury of the intestine and protective strategies against injury. Dig Dis Sci (2004) 2.54
Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition. Circulation (2008) 2.37
Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br J Pharmacol (2003) 2.26
Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21. Kidney Int (2012) 2.12
IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2. Cardiovasc Res (2004) 2.12
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
Discovery of a new function of cyclooxygenase (COX)-2: COX-2 is a cardioprotective protein that alleviates ischemia/reperfusion injury and mediates the late phase of preconditioning. Cardiovasc Res (2002) 1.90
Preconditioning: a paradigm shift in the biology of myocardial ischemia. Am J Physiol Heart Circ Physiol (2006) 1.88
An essential role of the JAK-STAT pathway in ischemic preconditioning. Proc Natl Acad Sci U S A (2001) 1.73
A novel role of microRNA in late preconditioning: upregulation of endothelial nitric oxide synthase and heat shock protein 70. Circ Res (2009) 1.69
The role of TNF-alpha receptors p55 and p75 in acute myocardial ischemia/reperfusion injury and late preconditioning. J Mol Cell Cardiol (2008) 1.61
Daughter, you broke my heart: accidental thrombosis at a muscular bridge. Tex Heart Inst J (2006) 1.60
Loss of ischaemic preconditioning in ovariectomized rat hearts: possible involvement of impaired protein kinase C epsilon phosphorylation. Cardiovasc Res (2008) 1.54
Mechanism of cyclooxygenase-2 upregulation in late preconditioning. J Mol Cell Cardiol (2003) 1.45
Ischemic preconditioning targets the respiration of synaptic mitochondria via protein kinase C epsilon. J Neurosci (2008) 1.43
Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection. J Clin Invest (2002) 1.34
MicroRNAs: new players in cardiac injury and protection. Mol Pharmacol (2011) 1.26
Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat. J Physiol (2005) 1.24
Gene therapy with inducible nitric oxide synthase protects against myocardial infarction via a cyclooxygenase-2-dependent mechanism. Circ Res (2003) 1.23
Susceptibility of the heart to ischaemia-reperfusion injury and exercise-induced cardioprotection are sex-dependent in the rat. J Physiol (2005) 1.16
Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway. Circulation (2009) 1.15
Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway. Circulation (2007) 1.15
Thioredoxin and ventricular remodeling. J Mol Cell Cardiol (2006) 1.14
Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts. J Mol Cell Cardiol (2008) 1.13
Cardioprotection by postconditioning in conscious rats is limited to coronary occlusions <45 min. Am J Physiol Heart Circ Physiol (2006) 1.13
Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction. J Mol Cell Cardiol (2004) 1.12
Remote ischemic preconditioning delays the onset of acute mountain sickness in normobaric hypoxia. Physiol Rep (2015) 1.09
Ischemic conditioning by short periods of reperfusion attenuates renal ischemia/reperfusion induced apoptosis and autophagy in the rat. J Biomed Sci (2009) 1.09
Gene therapy with iNOS provides long-term protection against myocardial infarction without adverse functional consequences. Am J Physiol Heart Circ Physiol (2005) 1.09
Therapeutic potential of intermittent hypoxia: a matter of dose. Am J Physiol Regul Integr Comp Physiol (2014) 1.07
Ischemic preconditioning via epsilon protein kinase C activation requires cyclooxygenase-2 activation in vitro. Neuroscience (2007) 1.06
Gene program for cardiac cell survival induced by transient ischemia in conscious pigs. Proc Natl Acad Sci U S A (2001) 1.06
Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation. Antioxid Redox Signal (2009) 1.06
Hypercholesterolemia abrogates late preconditioning via a tetrahydrobiopterin-dependent mechanism in conscious rabbits. Circulation (2005) 1.06
Role of bradykinin in preconditioning and protection of the ischaemic myocardium. Br J Pharmacol (2002) 1.06
Cardioprotection and myocardial reperfusion: pitfalls to clinical application. Circ Res (2013) 1.03
Fibroblast growth factor-2 and cardioprotection. Heart Fail Rev (2007) 1.03
Substrate- and isoform-specific proteome stability in normal and stressed cardiac mitochondria. Circ Res (2012) 1.02
The late phase of preconditioning and its natural clinical application--gene therapy. Heart Fail Rev (2007) 1.02
Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions. Br J Pharmacol (2007) 1.01
Delayed adaptation of the heart to stress: late preconditioning. Stroke (2004) 1.01
Role of nitric oxide in regulating aldose reductase activation in the ischemic heart. J Biol Chem (2008) 1.01
Priming adult stem cells by hypoxic pretreatments for applications in regenerative medicine. J Biomed Sci (2013) 1.00
NF-kappaB driven cardioprotective gene programs; Hsp70.3 and cardioprotection after late ischemic preconditioning. J Mol Cell Cardiol (2010) 0.99
Abdominal surgical incision induces remote preconditioning of trauma (RPCT) via activation of bradykinin receptors (BK2R) and the cytochrome P450 epoxygenase pathway in canine hearts. Cardiovasc Drugs Ther (2011) 0.99
Mild exercise training, cardioprotection and stress genes profile. Eur J Appl Physiol (2007) 0.98
Carbon monoxide induces a late preconditioning-mimetic cardioprotective and antiapoptotic milieu in the myocardium. J Mol Cell Cardiol (2011) 0.97
The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning. PLoS One (2012) 0.96
MicroRNAs in ischemia-reperfusion injury. Am J Cardiovasc Dis (2012) 0.94
Late preconditioning induced by NO donors, adenosine A1 receptor agonists, and delta1-opioid receptor agonists is mediated by iNOS. Am J Physiol Heart Circ Physiol (2005) 0.94
Role of microRNAs in cardiac preconditioning. J Cardiovasc Pharmacol (2010) 0.94
Activation of cardiac muscarinic M3 receptors induces delayed cardioprotection by preserving phosphorylated connexin43 and up-regulating cyclooxygenase-2 expression. Br J Pharmacol (2010) 0.93
Extracellular signalling molecules in the ischaemic/reperfused heart - druggable and translatable for cardioprotection? Br J Pharmacol (2014) 0.93
Rapamycin protects against myocardial ischemia-reperfusion injury through JAK2-STAT3 signaling pathway. J Mol Cell Cardiol (2012) 0.93
Nitrite activates protein kinase A in normoxia to mediate mitochondrial fusion and tolerance to ischaemia/reperfusion. Cardiovasc Res (2013) 0.93
Identification of inducible nitric oxide synthase in peripheral blood cells as a mediator of myocardial ischemia/reperfusion injury. Basic Res Cardiol (2012) 0.93
Sulindac confers high level ischemic protection to the heart through late preconditioning mechanisms. Proc Natl Acad Sci U S A (2009) 0.93
Compensatory proteome adjustments imply tissue-specific structural and metabolic reorganization following episodic hypoxia or anoxia in the epaulette shark (Hemiscyllium ocellatum). Physiol Genomics (2010) 0.92
Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling. Am J Physiol Heart Circ Physiol (2009) 0.92
Cyclooxygenase-2 mediates the delayed cardioprotection induced by hydrogen sulfide preconditioning in isolated rat cardiomyocytes. Pflugers Arch (2007) 0.92
Endothelial nitric oxide synthase is not necessary for the early phase of ischemic preconditioning in the mouse. J Mol Cell Cardiol (2008) 0.92
Effect of acute hyperglycaemia and diabetes mellitus with and without short-term insulin treatment on myocardial ischaemic late preconditioning in the rabbit heart in vivo. Pflugers Arch (2003) 0.91
Molecular mechanisms in exercise-induced cardioprotection. Cardiol Res Pract (2011) 0.90
Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia. Cardiovasc Res (2011) 0.90
Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1. J Mol Cell Cardiol (2010) 0.90
Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion. Basic Res Cardiol (2012) 0.90
Ischaemic conditioning: pitfalls on the path to clinical translation. Br J Pharmacol (2015) 0.89
Heme oxygenase-1 induction enhances cell survival and restores contractility to unvascularized three-dimensional adult cardiomyocyte grafts implanted in vivo. Tissue Eng Part A (2011) 0.89
Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs. J Pharmacol Exp Ther (2003) 0.89
Therapeutic receptor targets of ischemic preconditioning. Cardiovasc Res (2002) 0.89
Investigation of reperfusion injury and ischemic preconditioning in microsurgery. Microsurgery (2009) 0.88
Osteopontin protects against cardiac ischemia-reperfusion injury through late preconditioning. Heart Vessels (2009) 0.88
Nitrite as a mediator of ischemic preconditioning and cytoprotection. Nitric Oxide (2011) 0.88
Evidence that the acute phase of ischemic preconditioning does not require signaling by the A 2B adenosine receptor. J Mol Cell Cardiol (2010) 0.88
Molecular mechanisms mediating preconditioning following chronic ischemia differ from those in classical second window. Am J Physiol Heart Circ Physiol (2010) 0.86
Sublethal transient global ischemia stimulates migration of neuroblasts and neurogenesis in mice. Transl Stroke Res (2010) 0.86
The late phase of ischemic preconditioning induces a prosurvival genetic program that results in marked attenuation of apoptosis. J Mol Cell Cardiol (2007) 0.85
Free-radical production triggered by hyperthermia contributes to heat stress-induced cardioprotection in isolated rat hearts. Br J Pharmacol (2002) 0.85
Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1α. J Cell Mol Med (2015) 0.84
Nicorandil attenuates the mitochondrial Ca2+ overload with accompanying depolarization of the mitochondrial membrane in the heart. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.84
Cardiomyocyte overexpression of the α1A-adrenergic receptor in the rat phenocopies second but not first window preconditioning. Am J Physiol Heart Circ Physiol (2012) 0.84
Protective effect of lipopolysaccharide preconditioning in hepatic ischaemia reperfusion injury. HPB (Oxford) (2010) 0.84
Acute, delayed and chronic remote ischemic conditioning is associated with downregulation of mTOR and enhanced autophagy signaling. PLoS One (2014) 0.84
Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences. Basic Res Cardiol (2011) 0.84
Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences. Basic Res Cardiol (2011) 0.84
Preemptive conditioning of the swine heart by H11 kinase/Hsp22 provides cardiac protection through inducible nitric oxide synthase. Am J Physiol Heart Circ Physiol (2011) 0.84
Altered expression of mitochondrial electron transport chain proteins and improved myocardial energetic state during late ischemic preconditioning. Am J Physiol Heart Circ Physiol (2012) 0.84
Exercise and the cardiovascular system. Cardiol Res Pract (2012) 0.83
Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo. Stem Cells Transl Med (2014) 0.82
Nicorandil induces late preconditioning against myocardial infarction in conscious rabbits. Am J Physiol Heart Circ Physiol (2003) 0.82
Exercise does not increase cyclooxygenase-2 myocardial levels in young or senescent hearts. J Physiol Sci (2010) 0.82
Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPAR-α. Proc Natl Acad Sci U S A (2014) 0.81
Adjuvant cardioprotection in cardiac surgery: update. Biomed Res Int (2014) 0.81
Aldose reductase decreases endoplasmic reticulum stress in ischemic hearts. Chem Biol Interact (2008) 0.80
The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats. Am J Physiol Heart Circ Physiol (2007) 0.80
Is nitrite the circulating endocrine effector of remote ischemic preconditioning? Circ Res (2014) 0.80
Organ preconditioning: the past, current status, and related lung studies. J Zhejiang Univ Sci B (2006) 0.80
Cardioprotection acquired through exercise: the role of ischemic preconditioning. Curr Cardiol Rev (2014) 0.79