Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level.
|
Circulation
|
2000
|
3.85
|
2
|
cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits.
|
Neuron
|
1997
|
3.21
|
3
|
Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk.
|
Science
|
1987
|
2.50
|
4
|
Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation.
|
Circ Res
|
2000
|
2.38
|
5
|
GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents.
|
Science
|
1992
|
2.09
|
6
|
The agonist effect of dihydropyridines on Ca channels.
|
Nature
|
1984
|
2.07
|
7
|
Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy.
|
Circ Res
|
2001
|
1.83
|
8
|
The alpha subunit of the GTP binding protein Gk opens atrial potassium channels.
|
Science
|
1987
|
1.79
|
9
|
Whole-cell and single-channel calcium currents of isolated smooth muscle cells from saphenous vein.
|
Circ Res
|
1987
|
1.63
|
10
|
Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice.
|
J Biol Chem
|
1998
|
1.60
|
11
|
Dual effects of dihydropyridines on whole cell and unitary calcium currents in single ventricular cells of guinea-pig.
|
J Physiol
|
1986
|
1.50
|
12
|
Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel.
|
J Biol Chem
|
1993
|
1.44
|
13
|
Splice variants of the alpha subunit of the G protein Gs activate both adenylyl cyclase and calcium channels.
|
Science
|
1989
|
1.39
|
14
|
Differential contribution by conserved glutamate residues to an ion-selectivity site in the L-type Ca2+ channel pore.
|
FEBS Lett
|
1993
|
1.28
|
15
|
Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart.
|
Proc Natl Acad Sci U S A
|
1993
|
1.23
|
16
|
Superinhibition of sarcoplasmic reticulum function by phospholamban induces cardiac contractile failure.
|
J Biol Chem
|
2001
|
1.21
|
17
|
Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation.
|
J Biol Chem
|
2000
|
1.16
|
18
|
The calcium channel blocker nitrendipine blocks sodium channels in neonatal rat cardiac myocytes.
|
Circ Res
|
1985
|
1.16
|
19
|
Profile of the oppositely acting enantiomers of the dihydropyridine 202-791 in cardiac preparations: receptor binding, electrophysiological, and pharmacological studies.
|
Biochem Biophys Res Commun
|
1985
|
1.11
|
20
|
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
|
Mol Pharmacol
|
1987
|
1.11
|
21
|
Mechanisms of impaired beta-adrenergic receptor signaling in G(alphaq)-mediated cardiac hypertrophy and ventricular dysfunction.
|
Mol Pharmacol
|
2000
|
1.08
|
22
|
Evidence for direct interaction of Gs alpha with the Ca2+ channel of skeletal muscle.
|
J Biol Chem
|
1991
|
1.07
|
23
|
Single-channel analysis of a cloned human heart L-type Ca2+ channel alpha 1 subunit and the effects of a cardiac beta subunit.
|
Biochem Biophys Res Commun
|
1993
|
1.07
|
24
|
Alpha-subunit of Gs directly activates cardiac calcium channels in lipid bilayers.
|
Am J Physiol
|
1988
|
1.05
|
25
|
Molecular localization of regions in the L-type calcium channel critical for dihydropyridine action.
|
Neuron
|
1993
|
1.04
|
26
|
The nature and origin of spontaneous noise in G protein-gated ion channels.
|
J Gen Physiol
|
1991
|
1.04
|
27
|
Bepridil block of cardiac calcium and sodium channels.
|
J Pharmacol Exp Ther
|
1986
|
1.02
|
28
|
Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: enhanced basal catalytic activity and function without increased cardiomyocyte beta-adrenergic signalling.
|
Biochemistry
|
1999
|
1.02
|
29
|
Amino acid substitutions in the rat Na+, K(+)-ATPase alpha 2-subunit alter the cation regulation of pump current expressed in HeLa cells.
|
J Physiol
|
1996
|
1.02
|
30
|
Phospholamban deficiency alters inactivation kinetics of L-type Ca2+ channels in mouse ventricular myocytes.
|
Am J Physiol
|
1997
|
1.01
|
31
|
Recovery of Ca currents from inactivation: the roles of Ca influx, membrane potential, and cellular metabolism.
|
Cell Mol Neurobiol
|
1983
|
1.01
|
32
|
The properties of batrachotoxin-modified cardiac Na channels, including state-dependent block by tetrodotoxin.
|
J Gen Physiol
|
1987
|
0.98
|
33
|
Two mechanisms for positive inotropism of low-K Ringer solution in bullfrog atrium.
|
Nature
|
1977
|
0.98
|
34
|
Beta gamma dimers of G proteins inhibit atrial muscarinic K+ channels.
|
J Biol Chem
|
1990
|
0.97
|
35
|
Atrotoxin: a specific agonist for calcium currents in heart.
|
Science
|
1985
|
0.97
|
36
|
Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels.
|
Toxicon
|
1992
|
0.96
|
37
|
Interaction between caffeine and adenosine on the membrane current and tension component in the bullfrog atrial muscle.
|
Jpn J Physiol
|
1979
|
0.95
|
38
|
Distinctive functional properties of the neuronal BII (class E) calcium channel.
|
Receptors Channels
|
1994
|
0.95
|
39
|
Sarcoplasmic reticulum Ca(2+) atpase (SERCA) 1a structurally substitutes for SERCA2a in the cardiac sarcoplasmic reticulum and increases cardiac Ca(2+) handling capacity.
|
Circ Res
|
2001
|
0.93
|
40
|
Effect of extracellular pH on sodium current in isolated, single rat ventricular cells.
|
J Membr Biol
|
1984
|
0.93
|
41
|
Four conductance levels of cloned cardiac L-type Ca2+ channel alpha1 and alpha1/beta subunits.
|
FEBS Lett
|
1998
|
0.92
|
42
|
Voltage-dependent activation of potassium current in Helix neurones by endogenous cellular calcium.
|
J Physiol
|
1983
|
0.91
|
43
|
Differential regulation of inotropy and lusitropy in overexpressed Gsalpha myocytes through cAMP and Ca2+ channel pathways.
|
J Clin Invest
|
1999
|
0.90
|
44
|
5-Hydroxytryptamine antagonist ICS 205-930 blocks cardiac potassium, sodium and calcium currents.
|
J Pharmacol Exp Ther
|
1988
|
0.90
|
45
|
Recombinant alpha i-3 subunit of G protein activates Gk-gated K+ channels.
|
J Biol Chem
|
1989
|
0.90
|
46
|
ACE inhibition improves cardiac NE uptake and attenuates sympathetic nerve terminal abnormalities in heart failure.
|
Am J Physiol
|
1999
|
0.90
|
47
|
Charged amino acids near the pore entrance influence ion-conduction of a human L-type cardiac calcium channel.
|
Mol Cell Biochem
|
1997
|
0.89
|
48
|
Effects of a new antiarrhythmic compound SUN 1165 [N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride] on the sodium currents in isolated single rat ventricular cells.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1984
|
0.89
|
49
|
The effects of caffeine on the electrical properties of isolated, single rat ventricular cells.
|
Jpn J Physiol
|
1984
|
0.88
|
50
|
Reduction of the slow inward current of isolated rat ventricular cells by thiamylal and halothane.
|
Acta Anaesthesiol Scand
|
1985
|
0.87
|
51
|
Blockage of the sodium current in isolated single cells from rat ventricle with mexiletine and disopyramide.
|
J Mol Cell Cardiol
|
1985
|
0.86
|
52
|
Alpha-subunit of Gk activates atrial K+ channels of chick, rat, and guinea pig.
|
Am J Physiol
|
1988
|
0.86
|
53
|
Signal transduction by G proteins.
|
Kidney Int Suppl
|
1987
|
0.86
|
54
|
Modulation of cardiac Ca2+ channels by isoproterenol studied in transgenic mice with altered SR Ca2+ content.
|
Am J Physiol
|
1997
|
0.86
|
55
|
An analysis of the action of ATP and related compounds on membrane current and tension components in bullfrog atrial muscle.
|
Jpn J Physiol
|
1977
|
0.86
|
56
|
A novel mechanism for myocardial stunning involving impaired Ca(2+) handling.
|
Circ Res
|
2001
|
0.85
|
57
|
Changes in ionic currents and beta-adrenergic receptor signaling in hypertrophied myocytes overexpressing G alpha(q).
|
Am J Physiol Heart Circ Physiol
|
2000
|
0.85
|
58
|
Roles of G proteins in coupling of receptors to ionic channels and other effector systems.
|
Crit Rev Biochem Mol Biol
|
1990
|
0.85
|
59
|
Stabilizing effects of adenosine on the membrane currents and tension components of the bullfrog atrium.
|
Jpn J Physiol
|
1978
|
0.84
|
60
|
Nature of catecholamine-like actions of ATP and other energy rich nucleotides on the bullfrog atrial muscle.
|
Jpn J Physiol
|
1978
|
0.84
|
61
|
Effect of low temperature on the membrane currents and tension components of bullfrog atrial muscle.
|
Jpn J Physiol
|
1978
|
0.84
|
62
|
Zinc current in Helix soma membrane.
|
Comp Biochem Physiol C
|
1982
|
0.83
|
63
|
The effect of extracellular low pH on the plateau current in isolated, single rat ventricular cells--a voltage clamp study.
|
Jpn J Physiol
|
1983
|
0.83
|
64
|
Myocardial beta-adrenoceptor down-regulation by norepinephrine is linked to reduced norepinephrine uptake activity.
|
Eur J Pharmacol
|
1999
|
0.83
|
65
|
Effects of exogenously applied guanosine triphosphate on membrane current and tension of bullfrong atrial muscle.
|
J Mol Cell Cardiol
|
1978
|
0.82
|
66
|
Block of P-type Ca2+ channels in freshly dissociated rat cerebellar Purkinje neurons by diltiazem and verapamil.
|
Brain Res
|
1995
|
0.82
|
67
|
Hormonal regulation of pituitary GH3 cell K+ channels by Gk is mediated by its alpha-subunit.
|
FEBS Lett
|
1987
|
0.82
|
68
|
G protein coupling of receptors to ionic channels and other effector systems.
|
Soc Gen Physiol Ser
|
1990
|
0.82
|
69
|
Nanomolar concentrations of extracellular ATP activate membrane Ca channels in snail neurones.
|
Nature
|
1982
|
0.81
|
70
|
A novel enhancing effect of clofilium on transient outward-type cloned cardiac K+ channel currents.
|
Br J Pharmacol
|
1995
|
0.80
|
71
|
Direct coupling of G proteins to ionic channels.
|
Cold Spring Harb Symp Quant Biol
|
1988
|
0.80
|
72
|
Direct G-protein regulation of Ca2+ channels.
|
Ann N Y Acad Sci
|
1989
|
0.80
|
73
|
Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
|
Toxicon
|
1988
|
0.80
|
74
|
Ca2+ entry through cardiac L-type Ca2+ channels modulates beta-adrenergic stimulation in mouse ventricular myocytes.
|
Pflugers Arch
|
1998
|
0.79
|
75
|
Molecular basis of regulation of ionic channels by G proteins.
|
Recent Prog Horm Res
|
1989
|
0.79
|
76
|
G protein coupling of receptors to ionic channels and other effector systems.
|
Br J Clin Pharmacol
|
1990
|
0.79
|
77
|
Modulation of pump function by mutations in the first transmembrane region of Na(+)-K(+)-ATPase alpha 1-subunit.
|
Am J Physiol
|
1996
|
0.79
|
78
|
Beta 2-adrenergic receptor regulation of the cardiac L-type Ca2+ channel coexpressed in a fibroblast cell line.
|
Receptor
|
1995
|
0.79
|
79
|
Overexpression of phospholamban alters inactivation kinetics of L-type Ca2+ channel currents in mouse atrial myocytes.
|
J Mol Cell Cardiol
|
1998
|
0.79
|
80
|
Effects of ATP on the membrane currents and tension components of bullfrog atrial muscle.
|
Nihon Seirigaku Zasshi
|
1976
|
0.78
|
81
|
Regulation of ionic channels by G proteins.
|
Adv Exp Med Biol
|
1991
|
0.78
|
82
|
Receptor-effector coupling by G proteins: purification of human erythrocyte Gi-2 and Gi-3 and analysis of effector regulation using recombinant alpha subunits synthesized in Escherichia coli.
|
Cold Spring Harb Symp Quant Biol
|
1988
|
0.78
|
83
|
Reduction in the myocardial sodium current by halothane and thiamylal.
|
Jpn J Physiol
|
1986
|
0.78
|
84
|
Diphenylhydantoin blocks cardiac calcium channels and binds to the dihydropyridine receptor.
|
Circ Res
|
1986
|
0.77
|
85
|
Excess lactate modulates ionic currents and tension components in frog atrial muscle.
|
J Mol Cell Cardiol
|
1981
|
0.77
|
86
|
Neurotoxins that act selectively on voltage-dependent cardiac calcium channels.
|
Circ Res
|
1987
|
0.77
|
87
|
Tails of the L-type Ca(2+) channel: to sense oxygen or not.
|
Circ Res
|
2000
|
0.76
|
88
|
Identification of G protein-gated and G protein-modulated ionic channels. Molecular basis for G protein action.
|
Soc Gen Physiol Ser
|
1989
|
0.76
|
89
|
Behavioral and hormonal basis of polygynous breeding in male bush warblers (Cettia diphone).
|
Gen Comp Endocrinol
|
1999
|
0.76
|
90
|
Control of K+ channels by G proteins.
|
J Bioenerg Biomembr
|
1991
|
0.76
|
91
|
Elevated myocardial interstitial norepinephrine concentration contributes to the regulation of Na+,K(+)-ATPase in heart failure.
|
Eur J Pharmacol
|
1996
|
0.76
|
92
|
[Sarcoidosis with diabetes insipidus and pituitary tumor].
|
Nihon Naika Gakkai Zasshi
|
2001
|
0.75
|
93
|
Permeability to various cations of the voltage-dependent sodium channel of rat single heart cells.
|
J Pharmacol Exp Ther
|
1984
|
0.75
|
94
|
Membrane calcium current in cardiac excitation: effects of ATP and related substances and sodium pump on bullfrog atrium.
|
Recent Adv Stud Cardiac Struct Metab
|
1978
|
0.75
|
95
|
G protein-gated channels. A third major category of ionic channels.
|
Am J Hypertens
|
1989
|
0.75
|
96
|
Networking ionic channels by G proteins.
|
Soc Gen Physiol Ser
|
1990
|
0.75
|
97
|
Comparative studies of thrombolysis with single-chain and two-chain recombinant tissue-type plasminogen activators in canine coronary thrombosis.
|
J Cardiovasc Pharmacol
|
1996
|
0.75
|
98
|
After effects of perfusion with glucose-insulin-potassium solution on the membrane current and tension components of frog atrial muscle.
|
Jpn Heart J
|
1982
|
0.75
|
99
|
Gating of atrial muscarinic K+ channels by G proteins.
|
Prog Clin Biol Res
|
1990
|
0.75
|
100
|
Antagonistic action of alpha- and beta-agonists on the bullfrog atrium.
|
Jpn J Physiol
|
1980
|
0.75
|
101
|
Interaction of adenosine and acetylcholine on the bullfrog atrium.
|
Jpn J Physiol
|
1981
|
0.75
|
102
|
Altered sarcoplasmic reticulum Ca2+ ATPase gene expression in congestive heart failure: effect of chronic norepinephrine infusion.
|
J Mol Cell Cardiol
|
1998
|
0.75
|
103
|
[Dynamic energy participation in electrogenesis of the myocardium (author's transl)].
|
Nihon Seirigaku Zasshi
|
1975
|
0.75
|