Published in J Biol Chem on December 13, 2000
Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Circ Res (2009) 2.12
Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure. Proc Natl Acad Sci U S A (2001) 1.97
Gene therapy in heart failure. Circ Res (2008) 1.79
Altered intracellular Ca2+ handling in heart failure. J Clin Invest (2005) 1.70
Beta-adrenergic stimulation and myocardial function in the failing heart. Heart Fail Rev (2009) 1.40
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest (2003) 1.33
Targeting calcium cycling proteins in heart failure through gene transfer. J Physiol (2003) 1.12
Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation. Pflugers Arch (2008) 1.08
Beta-adrenergic receptors in the failing heart: the good, the bad, and the unknown. J Clin Invest (2001) 1.05
Role of P2X purinergic receptors in the rescue of ischemic heart failure. Am J Physiol Heart Circ Physiol (2008) 1.01
AFos dissociates cardiac myocyte hypertrophy and expression of the pathological gene program. Circulation (2005) 0.97
Rescue of familial cardiomyopathies by modifications at the level of sarcomere and Ca2+ fluxes. J Mol Cell Cardiol (2010) 0.96
Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice. Circ Res (2013) 0.92
Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein. J Mol Cell Cardiol (2011) 0.92
Phospholamban overexpression in transgenic rabbits. Transgenic Res (2007) 0.91
Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses. J Clin Invest (2014) 0.89
Rodent models of heart failure: an updated review. Heart Fail Rev (2013) 0.85
Anti-erbB2 treatment induces cardiotoxicity by interfering with cell survival pathways. Breast Cancer Res (2006) 0.82
Gene therapy targets in heart failure: the path to translation. Clin Pharmacol Ther (2011) 0.81
Losartan reduces mortality in a genetic model of heart failure. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.80
PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban. J Clin Invest (2015) 0.79
Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout. Physiol Genomics (2013) 0.78
Gene and cell therapy for heart failure. Antioxid Redox Signal (2009) 0.77
Prostaglandin E2 does not attenuate adrenergic-induced cardiac contractile response. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.77
Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy. Proc Natl Acad Sci U S A (2015) 0.76
Phospholamban Ablation Using CRISPR/Cas9 System Improves Mortality in a Murine Heart Failure Model. PLoS One (2016) 0.75
The role of cell-mediated immunity in bacterial infections. Rev Infect Dis (1982) 9.26
Isochorismate synthase is required to synthesize salicylic acid for plant defence. Nature (2001) 7.43
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science (1996) 6.56
Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circ Res (1994) 5.01
Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science (1993) 4.53
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet (1997) 4.46
Cytoplasmic signaling pathways that regulate cardiac hypertrophy. Annu Rev Physiol (2001) 4.17
Transgenic Galphaq overexpression induces cardiac contractile failure in mice. Proc Natl Acad Sci U S A (1997) 3.89
Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level. Circulation (2000) 3.85
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development (1996) 3.84
Superconductivity at 43 K in SmFeAsO1-xFx. Nature (2008) 3.80
The CLAVATA1 receptor-like kinase requires CLAVATA3 for its assembly into a signaling complex that includes KAPP and a Rho-related protein. Plant Cell (1999) 3.62
The Genome Knowledgebase: a resource for biologists and bioinformaticists. Cold Spring Harb Symp Quant Biol (2003) 3.55
Biological functions of t cell lines with specificity for the intracellular bacterium Listeria monocytogenes in vitro and in vivo. J Exp Med (1982) 3.52
Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia. J Med Genet (2004) 3.45
Specific Lyt 123 cells are involved in protection against Listeria monocytogenes and in delayed-type hypersensitivity to listerial antigens. J Exp Med (1979) 3.31
Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC. Proc Natl Acad Sci U S A (2001) 3.28
Immunolocalization of sarcolemmal dihydropyridine receptor and sarcoplasmic reticular triadin and ryanodine receptor in rabbit ventricle and atrium. J Cell Biol (1995) 3.28
cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron (1997) 3.21
Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure. Proc Natl Acad Sci U S A (1998) 3.05
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature (1999) 2.95
Molecular architecture of membranes involved in excitation-contraction coupling of cardiac muscle. J Cell Biol (1995) 2.88
Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke (1993) 2.85
On the shape of the probability weighting function. Cogn Psychol (1999) 2.81
Rop GTPase-dependent dynamics of tip-localized F-actin controls tip growth in pollen tubes. J Cell Biol (2001) 2.80
Endothelial apoptosis in Braf-deficient mice. Nat Genet (1997) 2.77
Identification and characterization of polycystin-2, the PKD2 gene product. J Biol Chem (1999) 2.74
Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell (1999) 2.68
Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res (1987) 2.65
The stochastic nature of larval connectivity among nearshore marine populations. Proc Natl Acad Sci U S A (2008) 2.65
Decompensation of pressure-overload hypertrophy in G alpha q-overexpressing mice. Circulation (1998) 2.62
Immunohistochemical and electron microscopic study of interaction of Yersinia enterocolitica serotype O8 with intestinal mucosa during experimental enteritis. Infect Immun (1989) 2.60
Sino-MONICA project: a collaborative study on trends and determinants in cardiovascular diseases in China, Part i: morbidity and mortality monitoring. Circulation (2001) 2.56
T-cell subsets in delayed-type hypersensitivity, protection, and granuloma formation in primary and secondary Listeria infection in mice: superior role of Lyt-2+ cells in acquired immunity. Infect Immun (1988) 2.55
Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells. Am J Physiol Endocrinol Metab (2001) 2.50
Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk. Science (1987) 2.50
Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration. Invest Ophthalmol Vis Sci (1989) 2.44
Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation. Proc Natl Acad Sci U S A (1999) 2.44
Combination therapy with fluconazole and flucytosine for cryptococcal meningitis in Ugandan patients with AIDS. Clin Infect Dis (1998) 2.40
DSPP mutation in dentinogenesis imperfecta Shields type II. Nat Genet (2001) 2.39
Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation. Circ Res (2000) 2.38
The effect of troponin I phosphorylation on the Ca2+-binding properties of the Ca2+-regulatory site of bovine cardiac troponin. J Biol Chem (1982) 2.27
Fibroblast growth factor 2 control of vascular tone. Nat Med (1998) 2.21
Arabidopsis Rho-related GTPases: differential gene expression in pollen and polar localization in fission yeast. Plant Physiol (1998) 2.18
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev (1997) 2.17
Utility of upright tilt-table testing in the evaluation and management of syncope of unknown origin. Am J Med (1991) 2.16
Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. CHIB 201 International Study Group. Lancet (1997) 2.12
Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice. Mol Biol Cell (1995) 2.10
Perfusion fMRI detects deficits in regional CBF during memory-encoding tasks in MCI subjects. Neurology (2007) 2.09
GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. Science (1992) 2.09
The agonist effect of dihydropyridines on Ca channels. Nature (1984) 2.07
Interferon-gamma production by Listeria monocytogenes-specific T cells active in cellular antibacterial immunity. Eur J Immunol (1983) 2.06
Subunit structure of junctional feet in triads of skeletal muscle: a freeze-drying, rotary-shadowing study. J Cell Biol (1984) 1.99
Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy. Physiol Genomics (2001) 1.98
Reduced serum amino acid concentrations in infants with necrotizing enterocolitis. J Pediatr (2000) 1.97
Markers of foamy virus infections in monkeys, apes, and accidentally infected humans: appropriate testing fails to confirm suspected foamy virus prevalence in humans. AIDS Res Hum Retroviruses (1995) 1.92
Characterization of Bartonella henselae isolated from bacillary angiomatosis lesions in a human immunodeficiency virus-infected patient in Germany. Clin Infect Dis (1998) 1.87
Neutron-diffraction measurements of magnetic order and a structural transition in the parent BaFe2As2 compound of FeAs-based high-temperature superconductors. Phys Rev Lett (2008) 1.86
pH gating of ROMK (K(ir)1.1) channels: control by an Arg-Lys-Arg triad disrupted in antenatal Bartter syndrome. Proc Natl Acad Sci U S A (1999) 1.85
A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. Cancer Res (1999) 1.85
Mouse model of desmin-related cardiomyopathy. Circulation (2001) 1.84
Enhancement of Nitrate Reductase Activity by Benzyladenine in Agrostemma githago. Plant Physiol (1971) 1.84
Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy. Circ Res (2001) 1.83
Structural evaluation of phospholipid bicelles for solution-state studies of membrane-associated biomolecules. Biophys J (2001) 1.83
Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart. Nature (1982) 1.83
Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure. Circ Res (2000) 1.82
Head-upright tilt-table testing in evaluation and management of the malignant vasovagal syndrome. Am J Cardiol (1992) 1.82
Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure. J Clin Invest (1999) 1.82
The alpha subunit of the GTP binding protein Gk opens atrial potassium channels. Science (1987) 1.79
Coexistence of static magnetism and superconductivity in SmFeAsO(1-x)F(x) as revealed by muon spin rotation. Nat Mater (2009) 1.79
Phospholamban: a prominent regulator of myocardial contractility. Circ Res (1996) 1.78
Intraneuronal N-acetylaspartate supplies acetyl groups for myelin lipid synthesis: evidence for myelin-associated aspartoacylase. J Neurochem (2001) 1.77
Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation. Proc Natl Acad Sci U S A (2001) 1.76
Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J Biol Chem (1994) 1.76
Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes. J Physiol (1997) 1.73
Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts. Biochem J (1988) 1.73
Differentiation of convulsive syncope and epilepsy with head-up tilt testing. Ann Intern Med (1991) 1.72
Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality. Circulation (2001) 1.72
A single site (Ser16) phosphorylation in phospholamban is sufficient in mediating its maximal cardiac responses to beta -agonists. J Biol Chem (2000) 1.72
Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects. Am J Physiol (1998) 1.72
RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice. J Mol Cell Cardiol (2001) 1.72
Tuberculosis and multidrug resistance in Zambian prisons, 2000-2001. Int J Tuberc Lung Dis (2007) 1.71
Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1). Biochem Biophys Res Commun (2000) 1.68
Differentiation of species and strains among filamentous fungi by DNA fingerprinting. Curr Genet (1991) 1.65
Kinetic analysis of cytokine gene expression in the livers of naive and immune mice infected with Listeria monocytogenes. The immediate early phase in innate resistance and acquired immunity. J Immunol (1992) 1.63
Whole-cell and single-channel calcium currents of isolated smooth muscle cells from saphenous vein. Circ Res (1987) 1.63
Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency. Biochem J (2000) 1.63
In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency. Circ Res (1995) 1.61