Herpes simplex virus gE/gI sorts nascent virions to epithelial cell junctions, promoting virus spread.

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Published in J Virol on January 01, 2001

Authors

D C Johnson1, M Webb, T W Wisner, C Brunetti

Author Affiliations

1: Department of Molecular Microbiology & Immunology, Oregon Health Sciences University, Portland, Oregon 97201, USA. johnsoda@ohsu.edu

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The roles of host and donor cells in the rejection of skin allografts by T cell-deprived rats injected with syngeneic T cells. Eur J Immunol (1982) 2.48

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Establishment of mouse colonic carcinoma cell lines with different metastatic properties. Cancer Res (1980) 1.87

The effete in the heat: heat-related hospital presentations during a ten day heat wave. Aust N Z J Med (1995) 1.83

Interrelationships between the utilization of magnesium and the uptake of other bivalent cations by bacteria. Biochim Biophys Acta (1970) 1.68

Functions of metallothionein. Biochem Pharmacol (1982) 1.66

Inhibition of mixed lymphocyte response by monoclonal antibody specific for a rat T lymphocyte subset. Nature (1980) 1.65

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The utilization of magnesium by certain Gram-positive and Gram-negative bacteria. J Gen Microbiol (1966) 1.65

Cadmium-thionein and the protection by cadmium against the nephrotoxicity of mercury. Chem Biol Interact (1976) 1.56

Non-spindle microtubule organizing centers in metaphase II-arrested mouse oocytes. J Cell Biol (1985) 1.50

Mechanism of polar body formation in the mouse oocyte: an interaction between the chromosomes, the cytoskeleton and the plasma membrane. J Embryol Exp Morphol (1986) 1.45

Candida blastospores and pseudohyphae in blood smears. N Engl J Med (1971) 1.42

First admission incidence study of mania, 1975-1981. Br J Psychiatry (1995) 1.38

Pharmacological differences between the human and rat vanilloid receptor 1 (VR1). Br J Pharmacol (2001) 1.35

Binding of cadmium ions by rat liver and kidney. Biochem Pharmacol (1972) 1.32

The interactions of selenium with cadmium and mercury. Crit Rev Toxicol (1980) 1.23

A deletion mutant of the type IC restriction endonuclease EcoR1241 expressing a novel DNA specificity. Nucleic Acids Res (1993) 1.22

The influence of certain trace metals on bacterial growth and magnesium utilization. J Gen Microbiol (1968) 1.21

Herpes simplex virus with highly reduced gD levels can efficiently enter and spread between human keratinocytes. J Virol (2001) 1.21

Female twin with Hunter disease due to nonrandom inactivation of the X-chromosome: a consequence of twinning. Am J Med Genet (1992) 1.18

Orthotopic liver transplantation for benign hepatic neoplasms. Arch Surg (1995) 1.17

Content and intracellular distribution of the inducing metal in the primary rhabdomyosarcomata induced in the rat by cobalt, nickel and cadmium. Br J Cancer (1967) 1.17

Localisation of the MRC OX-2 glycoprotein on the surfaces of neurones. J Neurochem (1984) 1.14

Separation and quantification of ropinirole and some impurities using capillary liquid chromatography. J Chromatogr B Biomed Sci Appl (1999) 1.13

Induced synthesis of metallothionein by pig kidney cells in vitro in response to cadmium. Chem Biol Interact (1975) 1.10

Mechanical and structural properties underlying contraction of skeletal muscle fibers after partial 1-ethyl-3-[3-dimethylamino)propyl]carbodiimide cross-linking. Biophys J (1996) 1.09

Protection by zinc against cadmium toxicity. Biochem Pharmacol (1972) 1.04

Nomenclature of metallothionein. Experientia Suppl (1987) 1.04

The thermoluminescence response of doped SiO2 optical fibres subjected to photon and electron irradiations. Appl Radiat Isot (2008) 1.04

Electroconvulsive therapy (ECT) increases plasma growth hormone, prolactin, luteinising hormone and follicle-stimulating hormone but not thyrotropin or substance P. Psychoneuroendocrinology (1981) 1.02

Remission onset and relapse in depression. An 18-month prospective study of course for 100 first admission patients. J Affect Disord (2000) 1.01

Deletions within the DNA recognition subunit of M.EcoR124I that identify a region involved in protein-protein interactions between HsdS and HsdM. J Mol Biol (1994) 0.99

Surface labelling of the type I methyltransferase M.EcoR124I reveals lysine residues critical for DNA binding. J Mol Biol (1996) 0.99

The quickest way to A&E may be via the Segway. BMJ Case Rep (2013) 0.98

Cloned murine bradykinin receptor exhibits a mixed B1 and B2 pharmacological selectivity. Mol Pharmacol (1993) 0.98

Parthenogenesis and cytoskeletal organization in ageing mouse eggs. J Embryol Exp Morphol (1986) 0.97

The mechanism of acquired resistance to Co2+ and Ni2+ in Gram-positive and Gram-negative bacteria. Biochim Biophys Acta (1970) 0.97

Observations on rat cerebellar cells in vitro: influence of substratum, potassium concentration and relationship between neurones and astrocytes. Brain Res (1983) 0.96

Cadmium. Br Med Bull (1975) 0.96

Metabolism of zinc and copper in the neonate. (Zinc, copper)-thionein in the developing rat kidney and testis. J Biol Chem (1981) 0.95

Nonalcoholic fatty liver disease in overweight children and adolescents. Acta Paediatr (2007) 0.95

Clinical anophthalmos. Br J Ophthalmol (1987) 0.95

High-dose donor bone marrow infusions to enhance allograft survival: the effect of timing. Transplantation (1997) 0.95

The interaction of carcinogenic metals with tissues and body fluids. Cobalt and horse serum. Br J Cancer (1969) 0.94

Cloned human teratoma cells differentiate into neuron-like cells and other cell types in retinoic acid. J Cell Sci (1984) 0.93

The teratogenicity of methoxyacetic acid in the rat. Toxicol Lett (1984) 0.93

Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons. Cell Death Dis (2012) 0.93

The time-course of cadmium-thionein synthesis in the rat. Biochem Pharmacol (1976) 0.93

Interaction of carcinogenic metals with tissue and body fluids. Br J Cancer (1972) 0.93

Studies on the toxicity and metabolism of cadmium-thionein. Biochem Pharmacol (1977) 0.93

Effects of dimethoxyethyl phthalate, monomethoxyethyl phthalate, 2-methoxyethanol and methoxyacetic acid on post implantation rat embryos in culture. Toxicol Lett (1984) 0.92

Intranuclear distribution of the inducing metal in primary rhabdomyosarcomata induced in the rat by nickel, cobalt and cadmium. Br J Cancer (1972) 0.92

A monoclonal antibody, Py, distinguishes different classes of hippocampal neurons. J Neurosci (1989) 0.92

Metabolism of zinc and copper in the neonate: accumulation and function of (Zn, Cu)-metallothionein in the liver of the newborn rat. Br J Nutr (1981) 0.91

Influence of dietary cadmium on the distribution of the essential metals copper, zinc and iron in tissues of the rat. Chem Biol Interact (1976) 0.91

An investigation of the role of metallothioneins in protection against the acute toxicity of the cadmium ion. Biochem Pharmacol (1976) 0.91

Delayed hypersensitivity to chemically induced tumors in mice and correlation with an in vitro test. J Natl Cancer Inst (1969) 0.91

The metallothioneins. Biochem Soc Trans (1975) 0.91

Phase I/II study of gemcitabine plus vinorelbine as first-line chemotherapy of non-small-cell lung cancer. J Clin Oncol (2000) 0.90

Evaluation of two dosages of oral midazolam as a conscious sedation for physically and neurologically compromised pediatric dental patients. Pediatr Dent (1995) 0.90

The reversal of phenylarsenoxide inhibition of keto acid oxidation in mitochondrial and bacterial suspensions by lipoic acid and other disulphides. Biochem J (1967) 0.90

Effects of magnesium deficiency on ribosomal structure and function in certain Gram-positive and Gram-negative bacteria. Biochim Biophys Acta (1970) 0.90

Vascular complications, treatment, and outcome following orthotopic liver transplantation. Transplant Proc (1997) 0.89

Multiple bone marrow infusions to enhance acceptance of allografts from the same donor. Ann N Y Acad Sci (1995) 0.88

Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/MOAT). J Biol Chem (2001) 0.88

Biochemical effects of Cd 2+ -injury in the rat and mouse testis. J Reprod Fertil (1972) 0.87

Uptake of 63 Ni 2+ from its complexes with proteins and other ligands by mouse dermal fibroblasts in vitro. Br J Cancer (1972) 0.87

Functions of hepatic and renal metallothioneins in the control of the metabolism of cadmium and certain other bivalent cations. Experientia Suppl (1979) 0.87

A hypervariable locus D16S309 located at the distal end of 16p. Nucleic Acids Res (1992) 0.86

Metallothionein synthesis as an indication of the parenchymal origin of cells cultured from liver. Chem Biol Interact (1977) 0.86

The teratogenic potential of alkoxy acids in post-implantation rat embryo culture: structure-activity relationships. Toxicol Lett (1985) 0.86

Pyruvate metabolism by aminopterin-inhibited Aerobacter aerogenes. Biochem J (1968) 0.85

Pyruvate accumulation in growth-inhibited cultures of Aerobacter aerogenes. Biochem J (1968) 0.85

Molecular characterisation of cloned bradykinin B1 receptors from rat and human. Eur J Pharmacol (1999) 0.85

GTF2IRD1 regulates transcription by binding an evolutionarily conserved DNA motif 'GUCE'. FEBS Lett (2007) 0.85

Metabolism of zinc and copper in the neonate: changes in the concentrations and contents of thionein-bound Zn and Cu with age in the livers of the newborn of various mammalian species. Biochem Pharmacol (1981) 0.85

Fresh PBSC harvests, but not BM, show temperature-related loss of CD34 viability during storage and transport. Cytotherapy (2006) 0.85

Synthesis and function of metallothioneins. Nature (1981) 0.84

A morphological and biochemical study of the effects of L-cysteine on the renal uptake and nephrotoxicity of cadmium. Br J Exp Pathol (1981) 0.84

The effects of cadmium and copper on the renal uptake and metallothionein binding of gold in the rat and hamster. Chem Biol Interact (1982) 0.84

A randomized clinical trial of mupirocin in the eradication of Staphylococcus aureus nasal carriage in human immunodeficiency virus disease. J Infect Dis (1999) 0.83

Hand function after high dose rate brachytherapy for squamous cell carcinoma of the skin of the hand. Clin Oncol (R Coll Radiol) (2008) 0.83

The interaction of cadium-induced rat renal metallothionein with bivalent mercury in vitro. Chem Biol Interact (1980) 0.83

Cerebral lupus. Lancet (1994) 0.83

Respiration of metal induced rhabdomyosarcomata. Br J Cancer (1967) 0.83

Acute effects of cadmium on the pregnant rat and embryo-fetal development. Environ Health Perspect (1979) 0.83

Community based universal neonatal hearing screening by health visitors using otoacoustic emissions. Arch Dis Child Fetal Neonatal Ed (2001) 0.83

Teratogenicity of ionic cadmium in the Wistar rat. Arch Toxicol (1987) 0.83

Hypogammaglobulinemia and malakoplakia--effect of Bethanechol. Birth Defects Orig Artic Ser (1983) 0.82

Embryotoxicity and teratogenicity of thalidomide in rats. Teratology (1983) 0.82

The acute toxicity and teratogenicity of cadmium in the pregnant rat. J Appl Toxicol (1981) 0.82

Metabolism of zinc and copper in the neonate: accumulation of Cu in the gastrointestinal tract of the newborn rat. Br J Nutr (1981) 0.82

Histological demonstration of immunoreactive zinc metallothionein in liver and ileum of rat and man. Histochem J (1985) 0.82

Intestinal and hepatic binding of cadmium in the neonatal rat. Arch Toxicol (1983) 0.82

Recovery of viable CD34+ cells from cryopreserved hemopoietic progenitor cell products. Bone Marrow Transplant (2005) 0.81

The use of specific lysine modifications to locate the reaction site of cytochrome c with sulfite oxidase. Biochim Biophys Acta (1980) 0.81

Metabolism of zinc and copper in the neonate: effect of cadmium administration during late gestation in the rat on the zinc and copper metabolism of the newborn. Chem Biol Interact (1981) 0.81