PubRank

R J Coffey

Author PubWeight™ 192.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994 8.79
2 Production and auto-induction of transforming growth factor-alpha in human keratinocytes. Nature 1987 4.19
3 Trefoil peptides: less clandestine in the intestine. Science 1996 3.60
4 A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis. Int J Radiat Oncol Biol Phys 1994 3.29
5 Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest 1997 2.99
6 Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer. Gastroenterology 2000 2.99
7 Overexpression of transforming growth factor alpha in psoriatic epidermis. Science 1989 2.63
8 Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice. Cell 1990 2.63
9 Stereotactic radiosurgery for arteriovenous malformations of the brain. J Neurosurg 1991 2.41
10 Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta. Nat Med 1997 2.32
11 Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. J Clin Invest 2000 2.17
12 A new type of transforming growth factor-beta, TGF-beta 3. EMBO J 1988 2.12
13 Regulation of intestinal epithelial cell growth by transforming growth factor type beta. Proc Natl Acad Sci U S A 1989 2.09
14 Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proc Natl Acad Sci U S A 1995 2.07
15 Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc Natl Acad Sci U S A 1988 2.03
16 Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor. Proc Natl Acad Sci U S A 1999 1.96
17 Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinog 1991 1.95
18 Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha. Gastroenterology 1999 1.88
19 Hepatic processing of transforming growth factor beta in the rat. Uptake, metabolism, and biliary excretion. J Clin Invest 1987 1.88
20 Cholangiocarcinoma complicating primary sclerosing cholangitis. Ann Surg 1991 1.78
21 Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas. Proc Natl Acad Sci U S A 1991 1.77
22 Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2. Mol Cell Biol 1989 1.76
23 Epidermal growth factor-related peptides and their relevance to gastrointestinal pathophysiology. Gastroenterology 1995 1.74
24 Production of transforming growth factors by human colon cancer lines. Cancer Res 1986 1.74
25 Localization of transforming growth factor alpha and its receptor in gastric mucosal cells. Implications for a regulatory role in acid secretion and mucosal renewal. J Clin Invest 1989 1.69
26 Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells. J Cell Physiol 1987 1.68
27 Transforming growth factors and control of neoplastic cell growth. J Cell Biochem 1987 1.67
28 Stereotactic gamma knife radiosurgery. Initial North American experience in 207 patients. Arch Neurol 1990 1.64
29 Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model. Cancer Res 1987 1.61
30 Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 2001 1.59
31 Gamma knife for glioma: selection factors and survival. Int J Radiat Oncol Biol Phys 1996 1.56
32 Reversible drug-induced oxyntic atrophy in rats. Gastroenterology 2000 1.53
33 Fatal progression of posttraumatic dural arteriovenous fistulas refractory to multimodal therapy. Case report. J Neurosurg 2001 1.53
34 Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation. Mol Cell Biol 1998 1.52
35 Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells. Proc Natl Acad Sci U S A 1996 1.46
36 Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells. Exp Cell Res 2000 1.42
37 Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family. J Biol Chem 1994 1.40
38 Predictors of survival after curative resection of carcinoma of the colon and rectum. Cancer 1987 1.37
39 Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice. Mol Cell Biol 1996 1.36
40 A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells. Gastroenterology 1997 1.35
41 Hepatobiliary carcinoma associated with primary sclerosing cholangitis and chronic ulcerative colitis. Hum Pathol 1985 1.34
42 Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements. FASEB J 2001 1.33
43 Amphiregulin messenger RNA is elevated in psoriatic epidermis and gastrointestinal carcinomas. Cancer Res 1992 1.32
44 Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a metalloprotease inhibitor. Release of a predominant N-glycosylated 43-kDa soluble form. J Biol Chem 1998 1.30
45 Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras. Cancer Res 1997 1.27
46 Apical enrichment of human EGF precursor in Madin-Darby canine kidney cells involves preferential basolateral ectodomain cleavage sensitive to a metalloprotease inhibitor. J Cell Biol 1997 1.25
47 Basolateral targeting and efficient consumption of transforming growth factor-alpha when expressed in Madin-Darby canine kidney cells. J Biol Chem 1994 1.22
48 Increased production of transforming growth factor alpha following acute gastric injury. Gastroenterology 1992 1.20
49 Induction of transforming growth factor-alpha expression in human keratinocytes by phorbol esters. J Biol Chem 1989 1.20
50 Treatment of Ménétrier's disease with a monoclonal antibody against the epidermal growth factor receptor. N Engl J Med 2000 1.20
51 Antioxidant-induced nuclear translocation of CCAAT/enhancer-binding protein beta. A critical role for protein kinase A-mediated phosphorylation of Ser299. J Biol Chem 1997 1.20
52 Growth of normal human keratinocytes and fibroblasts in serum-free medium is stimulated by acidic and basic fibroblast growth factor. J Cell Physiol 1989 1.20
53 Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations. Am J Pathol 1992 1.19
54 Transforming growth factor beta regulation of cell proliferation. J Cell Physiol Suppl 1987 1.18
55 Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis. Cancer Res 1995 1.18
56 A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells. J Biol Chem 1997 1.18
57 Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo. J Clin Invest 1992 1.15
58 Growth stimulation of human breast cancer cells with anti-transforming growth factor beta antibodies: evidence for negative autocrine regulation by transforming growth factor beta. Cell Growth Differ 1990 1.13
59 Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice. J Cell Biol 1995 1.13
60 Propranolol therapy in thyrotoxicosis. A review of 84 patients undergoing surgery. Am J Med 1979 1.13
61 Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury. J Clin Invest 1995 1.11
62 Palliative gastroenterostomy for pancreatic cancer. Am J Surg 1984 1.09
63 Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex. Oncogene 2006 1.08
64 Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice. Proc Natl Acad Sci U S A 2000 1.08
65 Stereotactic surgery for mass lesions of the midbrain and pons. Neurosurgery 1985 1.07
66 Keratinocyte growth factor receptor ligands induce transforming growth factor alpha expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes. Cell Growth Differ 1994 1.05
67 The use of propranolol in the surgical treatment of thyrotoxic patients. Ann Surg 1973 1.05
68 Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells. Mol Biol Cell 2004 1.04
69 Keratinocytes produce and are regulated by transforming growth factors. Ann N Y Acad Sci 1988 1.03
70 Active signaling by Neu in transgenic mice. Oncogene 1998 1.03
71 Immunolocalization of transforming growth factor-alpha in normal and diseased human gastric mucosa. Hum Pathol 1995 1.03
72 Overexpression of transforming growth factor-alpha alters differentiation of gastric cell lineages. Dig Dis Sci 1996 1.03
73 Stereotactic radiosurgery of meningiomas. J Neurosurg 1991 1.02
74 Antioxidants reduce cyclooxygenase-2 expression, prostaglandin production, and proliferation in colorectal cancer cells. Cancer Res 1998 1.02
75 Characterization of the DiFi rectal carcinoma cell line derived from a familial adenomatous polyposis patient. In Vitro Cell Dev Biol 1993 1.02
76 Prostaglandin J2 and 15-deoxy-delta12,14-prostaglandin J2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells. Cancer Res 1999 1.00
77 Autocrine transforming growth factor alpha is dispensible for v-rasHa-induced epidermal neoplasia: potential involvement of alternate epidermal growth factor receptor ligands. Cancer Res 1995 0.99
78 Regulation of epithelial cell proliferation by transforming growth factors. J Cell Biochem 1989 0.99
79 Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis. Br J Cancer 1999 0.99
80 Interim report on the radiosurgical treatment of cerebral arteriovenous malformations. The influence of size, dose, time, and technical factors on obliteration rate. J Neurosurg 1995 0.98
81 Risk of injury to cranial nerves after gamma knife radiosurgery for skull base meningiomas: experience in 88 patients. J Neurosurg 1999 0.98
82 Expression of and response to growth regulatory peptides by two human pancreatic carcinoma cell lines. Pancreas 1990 0.98
83 Transforming growth factor-alpha (TGF alpha) concentrations increase in regenerating rat liver: evidence for a delayed accumulation of mature TGF alpha. Endocrinology 1993 0.98
84 Prolonged activation of the mitogen-activated protein kinase pathway promotes DNA synthesis in primary hepatocytes from p21Cip-1/WAF1-null mice, but not in hepatocytes from p16INK4a-null mice. Biochem J 1998 0.98
85 Helicobacter pylori upregulates expression of epidermal growth factor-related peptides, but inhibits their proliferative effect in MKN 28 gastric mucosal cells. J Clin Invest 1998 0.98
86 The proamphiregulin cytoplasmic domain is required for basolateral sorting, but is not essential for constitutive or stimulus-induced processing in polarized Madin-Darby canine kidney cells. J Biol Chem 2001 0.96
87 LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor. Br J Cancer 2013 0.95
88 Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade. Oncogene 1998 0.95
89 Role of transforming growth factor beta 1 in induction of colon carcinoma differentiation by hexamethylene bisacetamide. Cancer Res 1990 0.94
90 Stereotactic radiosurgery for glomus jugulare tumors: a preliminary report. Int J Radiat Oncol Biol Phys 1997 0.93
91 The role of stereotactic radiosurgery in the treatment of malignant skull base tumors. Int J Radiat Oncol Biol Phys 1997 0.93
92 Expression of trefoil peptides in the gastric mucosa of transgenic mice overexpressing transforming growth factor-alpha. Growth Factors 1996 0.92
93 Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes. Exp Dermatol 2000 0.92
94 Gastric adenocarcinoma complicating Gardner's syndrome in a North American woman. Gastroenterology 1985 0.91
95 Radiosurgery of acoustic neurinomas. Cancer 1991 0.91
96 TGF-alpha is a potent mitogen for primary cultures of guinea pig gastric mucous epithelial cells. Am J Physiol 1993 0.91
97 The role of radiosurgery and particulate embolization in the treatment of dural arteriovenous fistulas. J Neurosurg 1996 0.91
98 Inhibition of estrogen-induced breast cancer cell proliferation by reduction in autocrine transforming growth factor alpha expression. Cell Growth Differ 1994 0.90
99 Transforming growth factor-alpha gene expression and action in the seminiferous tubule: peritubular cell-Sertoli cell interactions. Endocrinology 1989 0.89
100 Production of transforming growth factor-alpha by normal rat small intestine. Am J Physiol 1991 0.89
101 The fine structure of mucosal epithelial cells of a pathological human gall bladder. Anat Rec 1966 0.89
102 Autonomous growth of human keratinocytes requires epidermal growth factor receptor occupancy. Cell Growth Differ 1993 0.88
103 Stereotactic radiosurgery using the gamma knife for acoustic neuromas. Int J Radiat Oncol Biol Phys 1995 0.88
104 Transforming growth factor-alpha production and autoinduction in a colorectal carcinoma cell line (DiFi) with an amplified epidermal growth factor receptor gene. Cancer Res 1993 0.88
105 Identification of an EGF/TGF-alpha receptor in primary cultures of guinea pig gastric mucous epithelial cells. Am J Physiol 1996 0.88
106 Inhibition of parietal cell H+ secretion by transforming growth factor alpha: a possible autocrine regulatory mechanism. Surgery 1990 0.88
107 Pharmacological inhibition of Ras-transformed epithelial cell growth is linked to down-regulation of epidermal growth factor-related peptides. Gastroenterology 1999 0.87
108 The surgical treatment of primary hyperparathyroidism: a 20 year experience. Ann Surg 1977 0.87
109 Effect of transforming growth factor-alpha on gastric acid secretion in rats and monkeys. Dig Dis Sci 1994 0.87
110 Acute hyperparathyroidism. Am Surg 1970 0.86
111 Pyrrolidinedithiocarbamate increases the therapeutic index of 5-fluorouracil in a mouse model. Gastroenterology 2000 0.86
112 Studies on uterine collagenase in tissue culture. I. Relationship of enzyme production to collagen metabolism. Biochim Biophys Acta 1971 0.86
113 Gamma knife radiosurgery for intracranial arteriovenous malformations in childhood and adolescence. Pediatr Neurosci 1989 0.86
114 Propranolol and thyroidectomy in the treatment of thyrotoxicosis. Ann Surg 1982 0.85
115 Transforming growth factor-beta isoforms in mammary neoplasia: more questions than answers. Hum Pathol 1992 0.84
116 K-Ras-independent effects of the farnesyl transferase inhibitor L-744,832 on cyclin B1/Cdc2 kinase activity, G2/M cell cycle progression and apoptosis in human pancreatic ductal adenocarcinoma cells. Neoplasia 2000 0.84
117 Studies on uterine collagenase in tissue culture. II. Effect of steroid hormones on enzyme production. Biochim Biophys Acta 1971 0.84
118 The acute effects of coffee and caffeine on human interdigestive exocrine pancreatic secretion. Pancreas 1986 0.84
119 Treatment with farnesyl-protein transferase inhibitor induces regression of mammary tumors in transforming growth factor (TGF) alpha and TGF alpha/neu transgenic mice by inhibition of mitogenic activity and induction of apoptosis. Clin Cancer Res 1999 0.84
120 Targeting transforming growth factor alpha expression to discrete loci of the neuroendocrine brain induces female sexual precocity. Proc Natl Acad Sci U S A 1997 0.83
121 Decrease in cranial nerve complications after radiosurgery for acoustic neuromas: a prospective study of dose and volume. Int J Radiat Oncol Biol Phys 1999 0.83
122 Expression and regulation of mRNA coding for acidic and basic fibroblast growth factor and transforming growth factor alpha in cells derived from human skin. Mol Endocrinol 1990 0.82
123 Human carcinoid cell production of paracrine growth factors that can stimulate fibroblast and endothelial cell growth. Cancer Res 1991 0.82
124 Mob-1, a Ras target gene, is overexpressed in colorectal cancer. Oncogene 1997 0.82
125 Transforming growth factor-alpha. Baillieres Clin Gastroenterol 1996 0.81
126 Gamma knife radiosurgery of meningiomas. Stereotact Funct Neurosurg 1991 0.81
127 Image-guided stereotactic surgery: a 10-year evolutionary experience. Stereotact Funct Neurosurg 1990 0.81
128 Stereotactic drainage of Aspergillus brain abscess with long-term survival: case report and review. Neurosurgery 1989 0.80
129 Brain metastatic lesions. Mayo Clin Proc 1994 0.79
130 Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine. Cell Growth Differ 1995 0.79
131 Cholangiocarcinoma complicating primary sclerosing cholangitis: cholangiographic appearances. Radiology 1985 0.79
132 Intervertebral disc space infection and osteomyelitis due to Hemophilus species: report of two cases and review. J Spinal Disord 1989 0.79
133 Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene. Cell Growth Differ 1993 0.78
134 Regional distribution of transforming growth factor-alpha and epidermal growth factor in normal and portal hypertensive gastric mucosa in humans. Dig Dis Sci 1995 0.78
135 Regulation of ovarian cell growth through the local production of transforming growth factor-alpha by theca cells. Endocrinology 1988 0.78
136 Transforming growth factor-alpha (TGF alpha) inhibition of parietal cell secretion: structural requirements for activity. Regul Pept 1993 0.78
137 Ras-mediated suppression of TGFbetaRII expression in intestinal epithelial cells involves Raf-independent signaling. Neoplasia 2001 0.78
138 Simultaneous presentation of symptomatic subependymomas in siblings: case reports and review. Neurosurgery 1993 0.77
139 Transforming growth factor-alpha (TGF-alpha) levels in human proximal gastrointestinal epithelium. Effect of mucosal injury and acid inhibition. Dig Dis Sci 1997 0.77
140 The dynamic expression of the epidermal growth factor receptor and epidermal growth factor ligand family in a differentiating intestinal epithelial cell line. Growth Factors 1999 0.77
141 Therapeutic manipulation of cytokines: transforming growth factor beta-1 protects mice treated with lethal doses of cytarabine. Am Surg 1994 0.77
142 Stimulatory actions of insulin-like growth factor-I and transforming growth factor-alpha on intestinal neurotensin and peptide YY. Endocrinology 1999 0.77
143 Increased gastroduodenal concentrations of transforming growth factor alpha in adaptation to aspirin in monkeys and rats. Gastroenterology 1996 0.77
144 Stereotactic radiosurgery of small intracranial tumors: neuropathological correlation in three patients. Surg Neurol 1990 0.76
145 Measurements of the oxygen enhancement ratio for high energy neutrons at the Fermilab. Int J Radiat Oncol Biol Phys 1977 0.76
146 Intrathecal baclofen and catheter tip inflammatory mass lesions (granulomas): a reevaluation of case reports and imaging findings in light of experimental, clinicopathological, and radiological evidence. Pain Med 2008 0.76
147 Chronic administration of transforming growth factor-beta suppresses erythropoietin-dependent erythropoiesis and induces tumour necrosis factor in vivo. Br J Haematol 1993 0.76
148 Cause of failure of lactation in mouse mammary tumor virus/human transforming growth factor alpha transgenic mice. Proc Soc Exp Biol Med 1994 0.76
149 Increased intestinal epithelial proliferation in metallothioneine-transforming growth factor alpha transgenic mice. Regul Pept 1998 0.76
150 Diagnosis and treatment of brainstem mass lesions by CT-guided stereotactic surgery. Appl Neurophysiol 1985 0.75
151 Comparison between transforming growth factor alpha and epidermal growth factor in the protection of rat gastric mucosa against drug-induced injury. Ital J Gastroenterol 1994 0.75
152 Gastric carcinoma and thrombotic thrombocytopenic purpura: association with plasma immune complex concentrations. Br Med J (Clin Res Ed) 1982 0.75
153 Understanding autocrine growth regulation. West J Med 1991 0.75
154 Forum for debate. Surg Neurol 1991 0.75
155 Gamma knife surgery for sellar and suprasellar tumors. Neurosurg Clin N Am 1992 0.75
156 Microarray foray. Breast Cancer Res 1999 0.75
157 Radiosurgery and microsurgery for AVMs. J Neurosurg 1998 0.75
158 In-office care of postoperative incisions. Med Times 1981 0.75
159 Integrating total quality management and quality assurance at the University of Michigan Medical Center. QRB Qual Rev Bull 1992 0.75
160 Socio-economic trends affecting surgery. Am Surg 1966 0.75
161 Biopsy--indications and technique. Cancer 1969 0.75
162 Success in CON process depends on constructive attitudes and actions. Hospitals 1982 0.75
163 A generic process for planning health services. Am J Health Plann 1977 0.75
164 Cushing's syndrome secondary to a benign paraganglioma. Am Surg 1970 0.75
165 Management engineering-a method to improve productivity. Top Health Care Financ 1977 0.75
166 Stereotactic radiosurgery of angiographically occult vascular malformations: indications and preliminary experience. Neurosurgery 1990 0.75
167 Interstitial brachytherapy of malignant brain tumors using computed tomography-guided stereotaxis and available imaging software: technical report. Neurosurgery 1987 0.75
168 Computerized models for strategic planning and marketing. Health Care Strateg Manage 1985 0.75
169 The tempo of change. Ann Surg 1968 0.75
170 Radiosurgery. Devices, principles, and rationale. Clin Neurosurg 1993 0.75
171 Historical highlights of hyperparathyroidism. Am Surg 1972 0.75
172 Expression and distribution of transforming growth factor-alpha within melanocytic lesions. J Invest Dermatol 1994 0.75
173 Acute abdominal trauma. Fundamentals of management. Postgrad Med 1966 0.75