G Martiny-Baron

Author PubWeight™ 28.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res 2000 3.02
2 Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity. J Biol Chem 1993 2.62
3 Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein. Cancer Res 1996 2.10
4 Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. FASEB J 2001 1.83
5 Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model. Cancer Res 2000 1.79
6 Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1. J Biol Chem 1997 1.41
7 Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis. Breast Cancer Res Treat 1995 1.26
8 Soluble VEGFR-1 secreted by endothelial cells and monocytes is present in human serum and plasma from healthy donors. Angiogenesis 2001 1.25
9 New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis. J Med Chem 2000 1.21
10 Two independent mechanisms essential for tumor angiogenesis: inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 1999 1.17
11 Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Res 1997 1.10
12 Identification of a soluble form of the angiopoietin receptor TIE-2 released from endothelial cells and present in human blood. Angiogenesis 2001 1.08
13 Expression of biologically active isoforms of the tumor angiogenesis factor VEGF in Escherichia coli. Biochem Biophys Res Commun 1996 0.95
14 Active interaction of human A375 melanoma cells with the lymphatics in vivo. Histochem Cell Biol 2000 0.95
15 VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of chorioallantoic membrane. Dev Biol 1996 0.92
16 An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells. Proc Natl Acad Sci U S A 1998 0.92
17 The pivotal role of VEGF in tumor angiogenesis: molecular facts and therapeutic opportunities. Cancer Metastasis Rev 1998 0.87
18 Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro. Biochim Biophys Acta 2000 0.85
19 The alpha-helical domain near the amino terminus is essential for dimerization of vascular endothelial growth factor. J Biol Chem 1998 0.83
20 Donor stromal cells from human blood engraft in NOD/SCID mice. Blood 2000 0.80
21 A new set of regulatory molecules in plants: A plant phospholipid similar to platelet-activating factor stimulates protein kinase and proton-translocating ATPase in membrane vesicles. Planta 1988 0.78
22 Chemiluminescence immunoassay for vascular endothelial growth factor (vascular permeability factor) in tumor-tissue homogenates. Clin Chem 1996 0.77
23 Novel antibodies directed against the extracellular domain of the human VEGF-receptor type II. Hybridoma 1997 0.77
24 Molecular aspects of the neuronal noradrenaline transporter. J Neural Transm Suppl 1991 0.75
25 Biochemical characterization and purification of the neuronal sodium-dependent noradrenaline transporter. J Neural Transm Suppl 1990 0.75