PubRank

S Shak

Author PubWeight™ 89.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001 44.67
2 Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999 11.78
3 Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol 2001 4.97
4 A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis. N Engl J Med 1992 2.57
5 Efficacy and safety of short-term administration of aerosolised recombinant human DNase I in adults with stable stage cystic fibrosis. Lancet 1993 2.50
6 The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone. Clin Exp Immunol 1996 1.94
7 First-line Herceptin monotherapy in metastatic breast cancer. Oncology 2001 1.60
8 Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus. J Clin Invest 1999 1.56
9 A glycan-phosphatidylinositol-specific phospholipase D in human serum. Science 1987 1.50
10 Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A 1986 1.45
11 Omega-oxidation is the major pathway for the catabolism of leukotriene B4 in human polymorphonuclear leukocytes. J Biol Chem 1984 1.44
12 Recombinant human DNase inhalation in normal subjects and patients with cystic fibrosis. A phase 1 study. JAMA 1992 1.43
13 Tumour gene expression predicts response to cetuximab in patients with KRAS wild-type metastatic colorectal cancer. Br J Cancer 2011 1.24
14 First-line, single-agent Herceptin(R) (trastuzumab) in metastatic breast cancer. a preliminary report. Eur J Cancer 2001 1.23
15 Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Partial purification and identification as a cytochrome P-450. J Clin Invest 1985 1.15
16 Prostaglandin I2 is not a major metabolite of arachidonic acid in cultured endothelial cells from human foreskin microvessels. J Clin Invest 1984 1.14
17 Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Suicidal inactivation by acetylenic fatty acids. J Biol Chem 1985 1.12
18 Engineering actin-resistant human DNase I for treatment of cystic fibrosis. Proc Natl Acad Sci U S A 1996 1.09
19 A novel dioxygenation product of arachidonic acid possesses potent chemotactic activity for human polymorphonuclear leukocytes. J Biol Chem 1983 1.02
20 First-line, single-agent Herceptin(trastuzumab) in metastatic breast cancer: a preliminary report. Eur J Cancer 2001 0.99
21 Colorimetric determination of DNase I activity with a DNA-methyl green substrate. Anal Biochem 1994 0.95
22 Carbon monoxide inhibits omega-oxidation of leukotriene B4 by human polymorphonuclear leukocytes: evidence that catabolism of leukotriene B4 is mediated by a cytochrome P-450 enzyme. Biochem Biophys Res Commun 1984 0.86
23 Dose-dependent in vitro effect of recombinant human DNase on rheological and transport properties of cystic fibrosis respiratory mucus. Eur Respir J 1995 0.86
24 Leukotriene B4 catabolism: quantitation of leukotriene B4 and its omega-oxidation products by reversed-phase high-performance liquid chromatography. Methods Enzymol 1987 0.85
25 Effects of rhDNase on purulent airway secretions in chronic bronchitis. Eur Respir J 1996 0.83
26 Production of chemotactic activity for polymorphonuclear leukocytes by cultured rat hepatocytes exposed to ethanol. J Clin Invest 1984 0.80
27 Coarse spray delivery to a localized region of the pulmonary airways for gene therapy. Hum Gene Ther 2000 0.79
28 Modification of CD4 immunoadhesin with monomethoxypoly(ethylene glycol) aldehyde via reductive alkylation. Bioconjug Chem 1994 0.76
29 The leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes is a membrane-associated, NADPH-dependent cytochrome P-450. Trans Assoc Am Physicians 1985 0.75
30 A possible explanation for leukocytic infiltration of the liver in acute alcoholic hepatitis: ethanol-induced generation by hepatocytes of a lipid chemotactic factor. Trans Assoc Am Physicians 1983 0.75