|
1
|
Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer.
|
J Clin Oncol
|
2001
|
4.97
|
|
2
|
Minimally important differences were estimated for the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) instrument using a combination of distribution- and anchor-based approaches.
|
J Clin Epidemiol
|
2005
|
4.29
|
|
3
|
A synthetic IgG-binding domain based on staphylococcal protein A.
|
Protein Eng
|
1989
|
3.31
|
|
4
|
Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data.
|
J Clin Oncol
|
2001
|
1.58
|
|
5
|
Rhizobium meliloti anthranilate synthase gene: cloning, sequence, and expression in Escherichia coli.
|
J Bacteriol
|
1989
|
1.47
|
|
6
|
A gene fusion system for generating antibodies against short peptides.
|
Gene
|
1987
|
1.42
|
|
7
|
Cooperative effects by the initiation codon and its flanking regions on translation initiation.
|
Gene
|
2001
|
1.33
|
|
8
|
Characterization of a succinate dehydrogenase complex solubilized from the cytoplasmic membrane of Bacillus subtilis with the nonionic detergent Triton X-100.
|
J Bacteriol
|
1979
|
1.29
|
|
9
|
Characterization of succinic dehydrogenase mutants of Bacillus subtilis by crossed immunoelectrophoresis.
|
J Bacteriol
|
1978
|
1.27
|
|
10
|
The Reaction Level Scale (RLS85). Manual and guidelines.
|
Acta Neurochir (Wien)
|
1988
|
1.24
|
|
11
|
Efficient secretion and purification of human insulin-like growth factor I with a gene fusion vector in Staphylococci.
|
Nucleic Acids Res
|
1985
|
1.18
|
|
12
|
Role of heme in synthesis and membrane binding of succinic dehydrogenase in Bacillus subtilis.
|
J Bacteriol
|
1979
|
1.14
|
|
13
|
A comparison of the Glasgow Coma Scale and the Reaction Level Scale (RLS85).
|
J Neurosurg
|
1988
|
1.05
|
|
14
|
Co-existing structures of an mRNA stability determinant. The 5' region of the Escherichia coli and Serratia marcescens ompA mRNA.
|
J Mol Biol
|
1993
|
1.02
|
|
15
|
Expression of human insulin-like growth factor I in bacteria: use of optimized gene fusion vectors to facilitate protein purification.
|
Biochemistry
|
1987
|
0.98
|
|
16
|
Evaluation of the pain suppressive effect of different frequencies of peripheral electrical stimulation in chronic pain conditions.
|
Acta Orthop Scand
|
1976
|
0.97
|
|
17
|
Production of specific antibodies against protein A fusion proteins.
|
EMBO J
|
1986
|
0.97
|
|
18
|
On acupuncture analgesia and the mechanism of pain.
|
Am J Chin Med (Gard City N Y)
|
1975
|
0.96
|
|
19
|
Isolation of cDNA sequences coding for a part of human tissue plasminogen activator.
|
Proc Natl Acad Sci U S A
|
1983
|
0.93
|
|
20
|
Dual affinity fusion approach and its use to express recombinant human insulin-like growth factor II.
|
Proc Natl Acad Sci U S A
|
1989
|
0.91
|
|
21
|
A recombinant Escherichia coli heat-stable enterotoxin (STa) fusion protein eliciting anti-STa neutralizing antibodies.
|
FEMS Microbiol Lett
|
1991
|
0.90
|
|
22
|
Bacillus subtilis mutant with temperature-sensitive net synthesis of phosphatidylethanolamine.
|
J Bacteriol
|
1977
|
0.88
|
|
23
|
Synthesis and secretion of a fibrinolytically active tissue-type plasminogen activator variant in Escherichia coli.
|
Gene
|
1991
|
0.88
|
|
24
|
A large convexity meningioma followed by liquorrhoea from a nasal encephalocele. A case report.
|
Acta Neurochir (Wien)
|
1981
|
0.87
|
|
25
|
Current reporting of responsiveness in acute cerebral disorders. A survey of the neurosurgical literature.
|
J Neurosurg
|
1988
|
0.86
|
|
26
|
Regulation of tryptophan genes in Rhizobium leguminosarum.
|
J Bacteriol
|
1982
|
0.86
|
|
27
|
Human immunodeficiency viral protease is catalytically active as a fusion protein: characterization of the fusion and native enzymes produced in Escherichia coli.
|
Arch Biochem Biophys
|
1990
|
0.86
|
|
28
|
Structure of a combination of Functional Independence Measure and Instrumental Activity Measure items in community-living persons: a study of individuals with cerebral palsy and spina bifida.
|
Arch Phys Med Rehabil
|
1996
|
0.82
|
|
29
|
Post-operative thromboembolism in neurosurgery. A study on the prophylactic effect of calf muscle stimulation plus dextran compared to low-dose heparin.
|
Acta Neurochir (Wien)
|
1986
|
0.81
|
|
30
|
Electro-acupuncture. Effect on pain threshold measured with electrical stimulation of teeth.
|
Brain Res
|
1973
|
0.81
|
|
31
|
Enhanced immunogenicity of recombinant peptide fusions containing multiple copies of a heterologous T helper epitope.
|
Eur J Immunol
|
1990
|
0.80
|
|
32
|
Fusion protein approach to improve the crystal quality of cytochrome bo(3) ubiquinol oxidase from Escherichia coli.
|
Biochim Biophys Acta
|
2000
|
0.80
|
|
33
|
Characterization of an extended form of recombinant human insulin-like growth factor II.
|
J Biol Chem
|
1991
|
0.79
|
|
34
|
Thrombin and H64A subtilisin cleavage of fusion proteins for preparation of human recombinant parathyroid hormone.
|
J Protein Chem
|
1991
|
0.79
|
|
35
|
Fibrinopeptide A and fibrinogen fragment B beta 15-42 and their relation to the operative trauma and post-operative thromboembolism in neurosurgical patients.
|
Acta Neurochir (Wien)
|
1987
|
0.78
|
|
36
|
An evaluation of different enzymatic cleavage methods for recombinant fusion proteins, applied on des(1-3)insulin-like growth factor I.
|
J Protein Chem
|
1992
|
0.78
|
|
37
|
Fusions to the 5' end of a gene encoding a two-domain analogue of staphylococcal protein A.
|
J Biotechnol
|
1992
|
0.77
|
|
38
|
Expression and characterization of a recombinant human parathyroid hormone secreted by Escherichia coli employing the staphylococcal protein A promoter and signal sequence.
|
J Biol Chem
|
1990
|
0.76
|
|
39
|
Assessment of responsiveness in acute cerebral disorders. A multicentre study on the reaction level scale (RLS 85).
|
Acta Neurochir (Wien)
|
1988
|
0.76
|
|
40
|
On-line strategies for determining trace levels of nitroaromatic explosives and related compounds in water.
|
J Chromatogr A
|
2006
|
0.76
|
|
41
|
Three human interferon-alpha 2 subvariants disclose structural and functional differences.
|
Eur J Biochem
|
1990
|
0.75
|
|
42
|
[Low frequent transcutaneous electrical stimulation for pain relief during labor].
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Lakartidningen
|
1976
|
0.75
|
|
43
|
Synchronization and desynchronization in the thalamus of the unanaesthetized decorticate cat.
|
Electroencephalogr Clin Neurophysiol
|
1971
|
0.75
|
|
44
|
Changes in synaptic function induced by blockage of axonal transport in the rabbit optic pathway.
|
Brain Res
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1978
|
0.75
|
|
45
|
Increase of pain threshold as a function of conditionsing electrical stimulation. An experimental study with application to electro-acupuncture for pain suppression.
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Am J Chin Med (Gard City N Y)
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1975
|
0.75
|
|
46
|
Weight loss and cerebrospinal-fluid leptin in obesity.
|
Lancet
|
1998
|
0.75
|
|
47
|
Purification and characterization of recombinant human insulin-like growth factor II (IGF-II) expressed as a secreted fusion protein in Escherichia coli.
|
Biotechnol Appl Biochem
|
1991
|
0.75
|
|
48
|
Respiratory depression after cimetidine reversed by physostigmine.
|
Intensive Care Med
|
1982
|
0.75
|
|
49
|
Electro-acupuncture and pain threshold.
|
Lancet
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1973
|
0.75
|
|
50
|
Differential stability of recombinant human insulin-like growth factor II in Escherichia coli and Staphylococcus aureus.
|
J Biotechnol
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1990
|
0.75
|
|
51
|
The relationship of hallucinations to the depth structures of the temporal lobe.
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Acta Neurochir (Wien)
|
1977
|
0.75
|
|
52
|
Acute head injuries: cooperative efforts in clinical assessment.
|
J Neurosurg
|
1981
|
0.75
|
|
53
|
On a free autologous graft of the greater omentum for spinal CSF drainage.
|
Z Kinderchir
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1986
|
0.75
|
|
54
|
Thalamo-cortical rhythmicity during reversible visual deafferentation.
|
Acta Physiol Scand
|
1970
|
0.75
|
|
55
|
[Prevention of thrombosis using heparin in neurosurgical intervention].
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Lakartidningen
|
1980
|
0.75
|
|
56
|
[Surgical education in the Swedish neurosurgery - has the postgraduate training fulfilled the expectations?].
|
Lakartidningen
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1982
|
0.75
|
|
57
|
A method for the evaluation of the efficiency of signal sequences for secretion and correct N-terminal processing of human parathyroid hormone produced in Escherichia coli.
|
Anal Biochem
|
1992
|
0.75
|
|
58
|
Localized thalamic rhythmicity induced by spinal and cortical lesions.
|
Electroencephalogr Clin Neurophysiol
|
1971
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0.75
|
|
59
|
Letter: Electro-acupuncture and pain threshold.
|
Lancet
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1973
|
0.75
|
|
60
|
Translocation and processing of various human parathyroid hormone peptides in Escherichia coli are differentially affected by protein-A-signal-sequence mutations.
|
Eur J Biochem
|
1994
|
0.75
|