Published in J Neurosci on February 01, 2001
Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol Biol Cell (2007) 1.80
The ABCA subfamily--gene and protein structures, functions and associated hereditary diseases. Pflugers Arch (2006) 1.03
"Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system. Mol Cell Biol (2006) 1.01
Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle. J Alzheimers Dis (2008) 0.97
Role of the Caenorhabditis elegans multidrug resistance gene, mrp-4, in gut granule differentiation. Genetics (2007) 0.92
Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation. Br J Cancer (2004) 0.92
The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Aβ fragment generation. Curr Alzheimer Res (2010) 0.89
A-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration. Front Psychiatry (2012) 0.89
ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms. Mol Cell Biol (2005) 0.86
Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment. Neurobiol Dis (2014) 0.85
Activation of proliferation and differentiation of dental follicle stem cells (DFSCs) by heat stress. Cell Prolif (2012) 0.85
ABC Transporters and the Alzheimer's Disease Enigma. Front Psychiatry (2012) 0.83
The role of ATP-binding cassette transporter A2 in childhood acute lymphoblastic leukemia multidrug resistance. Iran J Ped Hematol Oncol (2014) 0.80
Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa. J Perinat Med (2013) 0.80
"Late" macroendosomes and acidic endosomes in vertebrate motor nerve terminals. J Comp Neurol (2012) 0.80
Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter. Biochem J (2006) 0.79
Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies. Biomed Pharmacother (2012) 0.76
Misexpression of the Niemann-Pick disease type C1 (NPC1)-like protein in Arabidopsis causes sphingolipid accumulation and reproductive defects. Planta (2015) 0.76
Kleefstra syndrome in Hungarian patients: additional symptoms besides the classic phenotype. Mol Cytogenet (2016) 0.76
NeuN(+) neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure. Schizophr Res (2016) 0.75
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature (1996) 7.04
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur J Biochem (1997) 6.99
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies. Am J Pathol (1998) 5.47
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Am J Hum Genet (2001) 4.97
Phosphatidylinositol-3-OH kinases are Rab5 effectors. Nat Cell Biol (1999) 4.76
Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole. J Cell Biol (2001) 4.25
High-level semi-synthetic production of the potent antimalarial artemisinin. Nature (2013) 3.80
Elements of a paracrine tubular renin-angiotensin system along the entire nephron. Hypertension (1999) 3.33
Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway. Mol Cell (2001) 3.12
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity. Proc Natl Acad Sci U S A (1998) 3.01
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120. J Virol (2000) 2.97
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med (2001) 2.87
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc Natl Acad Sci U S A (1996) 2.70
Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data. Gut (2009) 2.62
Identifying individuals with physcian diagnosed COPD in health administrative databases. COPD (2009) 2.61
Proposal of the genera Anaerococcus gen. nov., Peptoniphilus gen. nov. and Gallicola gen. nov. for members of the genus Peptostreptococcus. Int J Syst Evol Microbiol (2001) 2.59
Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein. Ann Neurol (1998) 2.47
Analysis of repeated categorical data using generalized estimating equations. Stat Med (1994) 2.44
Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry. J Virol (1998) 2.38
Angiotensin-I-converting enzyme gene polymorphism and susceptibility to cough. Lancet (1994) 2.34
Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein. J Biol Chem (2000) 2.27
Mechanisms of DNA double strand break repair and chromosome aberration formation. Cytogenet Genome Res (2004) 2.26
Nutrient intakes of middle-aged men and women in China, Japan, United Kingdom, and United States in the late 1990s: the INTERMAP study. J Hum Hypertens (2003) 2.25
Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146,958 pregnancies. Ultrasound Obstet Gynecol (2015) 2.07
Over-expression of facilitative glucose transporter genes in human cancer. Biochem Biophys Res Commun (1990) 2.06
Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. J Exp Med (1998) 1.99
INTERMAP: the dietary data--process and quality control. J Hum Hypertens (2003) 1.88
A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism. Diabetes (1997) 1.86
Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. Circulation (1998) 1.86
Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science (2001) 1.84
Randomised clinical trial: an assessment of acupuncture on specific meridian or specific acupoint vs. sham acupuncture for treating functional dyspepsia. Aliment Pharmacol Ther (2012) 1.83
Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity. Nature (1997) 1.79
Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse. J Biol Chem (2000) 1.73
ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells. FEBS Lett (2001) 1.71
Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport. J Biol Chem (1997) 1.71
Roles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments. J Cell Biol (1998) 1.69
Measurement of glucose uptake and intracellular calcium concentration in single, living pancreatic beta-cells. J Biol Chem (2000) 1.69
A distinct spectrum of SLC26A4 mutations in patients with enlarged vestibular aqueduct in China. Clin Genet (2007) 1.66
Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance. Neuron (1999) 1.65
The cardiovirulent phenotype of coxsackievirus B3 is determined at a single site in the genomic 5' nontranslated region. J Virol (1995) 1.64
Coding mutations in p57KIP2 are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumors. Am J Hum Genet (1997) 1.62
The LIM homeobox gene Lhx9 is essential for mouse gonad formation. Nature (2000) 1.61
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase. Cancer Res (2001) 1.57
Forgotten mysteries in the early history of vitamin D. J Nutr (1999) 1.57
The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis. Hum Mol Genet (1997) 1.56
Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140. J Virol (2001) 1.55
The effects of anti-asthma drugs on mediator release from cultured human mast cells. Clin Exp Allergy (1998) 1.51
MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1. J Biol Chem (1997) 1.49
Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: purification by substrate affinity chromatography on cytidine 5'-diphospho-1,2-diacyl-sn-glycerol sepharose. Biochemistry (1976) 1.47
Comparison of FDG whole-body PET/CT and gadolinium-enhanced whole-body MRI for distant malignancies in patients with malignant tumors: a meta-analysis. Ann Oncol (2012) 1.47
Tetrahydrobiopterin and the regulation of hypoxic pulmonary vasoconstriction. Eur Respir J (2010) 1.46
Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice. Circulation (2001) 1.46
Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol Cell Biol (2001) 1.46
12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice. Circulation (2001) 1.45
Role of the actin bundling protein fascin in growth cone morphogenesis: localization in filopodia and lamellipodia. Cell Motil Cytoskeleton (2001) 1.45
Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors. Proc Natl Acad Sci U S A (2000) 1.44
Transcriptional repression of pref-1 by glucocorticoids promotes 3T3-L1 adipocyte differentiation. J Biol Chem (1999) 1.44
Synthesis and biological activities of novel antiallergic agents with 5-lipoxygenase inhibiting action. Bioorg Med Chem (2000) 1.43
Specific interaction of the potassium channel beta-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system. J Mol Biol (2001) 1.43
Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia. Neuroscience (2010) 1.43
SAR studies of diaryltriazoles against bacterial two-component regulatory systems and their antibacterial activities. Bioorg Med Chem Lett (1998) 1.42
Erwinia amylovora secretes harpin via a type III pathway and contains a homolog of yopN of Yersinia spp. J Bacteriol (1996) 1.42
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Synaptotagmin III is a novel isoform of rat synaptotagmin expressed in endocrine and neuronal cells. J Biol Chem (1994) 1.41
HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway. Cell Death Differ (2011) 1.40
Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae. Chem Biol (1998) 1.40
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury. Biochem Biophys Res Commun (1992) 1.39
Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas. J Oral Pathol Med (1989) 1.38
Telomerase is controlled by protein kinase Calpha in human breast cancer cells. J Biol Chem (1998) 1.38
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
BDNF and NT-3 induce intracellular Ca2+ elevation in hippocampal neurones. Neuroreport (1993) 1.34
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer. Oncogene (2008) 1.31
Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells. J Mol Endocrinol (2004) 1.30
Is the histaminergic neuron system a regulatory center for whole-brain activity? Trends Neurosci (1991) 1.30
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand. Proc Natl Acad Sci U S A (1993) 1.30
Abnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channel. Proc Natl Acad Sci U S A (1997) 1.29
Rotavirus alters paracellular permeability and energy metabolism in Caco-2 cells. Am J Physiol Gastrointest Liver Physiol (2000) 1.29
PPARgamma insufficiency promotes follicular thyroid carcinogenesis via activation of the nuclear factor-kappaB signaling pathway. Oncogene (2006) 1.28
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Tyrosine phosphorylation is required for mast cell activation by Fc epsilon RI cross-linking. J Immunol (1992) 1.27
Kir6.1: a possible subunit of ATP-sensitive K+ channels in mitochondria. Biochem Biophys Res Commun (1997) 1.27
Visualization of mitotic radial glial lineage cells in the developing rat brain by Cdc2 kinase-phosphorylated vimentin. Glia (1998) 1.27
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF. J Cell Biol (2001) 1.26
Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway. Br J Cancer (2008) 1.26
Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease. Clin Exp Immunol (2011) 1.25
Pyk2 and FAK differentially regulate progression of the cell cycle. J Cell Sci (2000) 1.25
X-ray diffraction of muscle labelled with antibody to troponin-C. Nat New Biol (1973) 1.25
Cell and tissue distribution and developmental change of neuron specific 14 kDa protein (phosphoneuroprotein 14). Brain Res (1993) 1.24
Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y. Neurosci Lett (1999) 1.23
Immunocytochemical observation of ghrelin-containing neurons in the rat arcuate nucleus. Neurosci Lett (2002) 1.23
Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles. J Med Chem (1999) 1.22
Immunohistochemical localization of leptin receptor in the rat brain. Neurosci Lett (1998) 1.22
Complete amino acid sequence and structure characterization of the taste-modifying protein, miraculin. J Biol Chem (1989) 1.21
Mouse extracellular superoxide dismutase: primary structure, tissue-specific gene expression, chromosomal localization, and lung in situ hybridization. Am J Respir Cell Mol Biol (1997) 1.21
Characterization of a cytokinesis defective (cyd1) mutant of Arabidopsis. J Exp Bot (1999) 1.21
Isolation and characterization of cDNA clones encoding cdc2 homologues from Oryza sativa: a functional homologue and cognate variants. Mol Gen Genet (1992) 1.20