Published in Science on May 25, 2001
ATP-sensitive potassium channelopathies: focus on insulin secretion. J Clin Invest (2005) 3.56
ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating. Nat Genet (2004) 2.85
Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice. J Clin Invest (2002) 2.74
Kir6.2 is required for adaptation to stress. Proc Natl Acad Sci U S A (2002) 2.60
Seizure termination by acidosis depends on ASIC1a. Nat Neurosci (2008) 2.18
Molecular targets for antiepileptic drug development. Neurotherapeutics (2007) 1.78
N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits. EMBO J (2003) 1.68
Cellular remodeling in heart failure disrupts K(ATP) channel-dependent stress tolerance. EMBO J (2003) 1.40
K(ATP) channel therapeutics at the bedside. J Mol Cell Cardiol (2005) 1.27
Nucleotide-gated KATP channels integrated with creatine and adenylate kinases: amplification, tuning and sensing of energetic signals in the compartmentalized cellular environment. Mol Cell Biochem (2004) 1.26
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K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration. Nat Neurosci (2012) 1.24
Identification of residues contributing to the ATP binding site of Kir6.2. EMBO J (2003) 1.22
Update on the role of substantia nigra pars reticulata in the regulation of seizures. Epilepsy Curr (2006) 1.19
Neuronal preconditioning by inhalational anesthetics: evidence for the role of plasmalemmal adenosine triphosphate-sensitive potassium channels. Anesthesiology (2009) 1.18
Single K ATP channel opening in response to action potential firing in mouse dentate granule neurons. J Neurosci (2011) 1.14
Dynamic regulation of the Kv2.1 voltage-gated potassium channel during brain ischemia through neuroglial interaction. J Neurosci (2008) 1.08
Mapping genetic modifiers of survival in a mouse model of Dravet syndrome. Genes Brain Behav (2013) 1.07
Gene targeting approach to clarification of ion channel function: studies of Kir6.x null mice. J Physiol (2003) 1.06
ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer. Proc Natl Acad Sci U S A (2003) 0.99
How ATP inhibits the open K(ATP) channel. J Gen Physiol (2008) 0.97
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The N-terminal transmembrane domain (TMD0) and a cytosolic linker (L0) of sulphonylurea receptor define the unique intrinsic gating of KATP channels. J Physiol (2006) 0.94
Dual regulation of the ATP-sensitive potassium channel by activation of cGMP-dependent protein kinase. Pflugers Arch (2008) 0.92
Ketone bodies, glycolysis, and KATP channels in the mechanism of the ketogenic diet. Epilepsia (2008) 0.91
ATP-sensitive potassium currents reduce the PGE2-mediated enhancement of excitability in adult rat sensory neurons. Brain Res (2007) 0.90
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DEND mutation in Kir6.2 (KCNJ11) reveals a flexible N-terminal region critical for ATP-sensing of the KATP channel. Biophys J (2008) 0.89
Ionic currents underlying the response of rat dorsal vagal neurones to hypoglycaemia and chemical anoxia. J Physiol (2007) 0.88
Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels. J Neurosci (2014) 0.87
Pre- and postsynaptic ATP-sensitive potassium channels during metabolic inhibition of rat hippocampal CA1 neurons. J Physiol (2002) 0.87
Nicorandil ameliorates ischaemia-reperfusion injury in the rat kidney. Br J Pharmacol (2011) 0.86
Ankyrin regulates KATP channel membrane trafficking and gating in excitable cells. Channels (Austin) (2010) 0.85
Glycolysis in energy metabolism during seizures. Neural Regen Res (2013) 0.85
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KATP channels confer survival advantage in cocaine overdose. Mol Psychiatry (2007) 0.84
Neuroprotective role of ATP-sensitive potassium channels in cerebral ischemia. Acta Pharmacol Sin (2012) 0.84
Iptakalim, an ATP-sensitive potassium channel opener, confers neuroprotection against cerebral ischemia/reperfusion injury in rats by protecting neurovascular unit cells. J Zhejiang Univ Sci B (2011) 0.83
Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition. Neuroscience (2011) 0.83
Single KATP channel opening in response to stimulation of AMPA/kainate receptors is mediated by Na+ accumulation and submembrane ATP and ADP changes. J Physiol (2013) 0.82
Characterization of an ATP-sensitive K(+) channel in rat carotid body glomus cells. Respir Physiol Neurobiol (2011) 0.82
Metabolic environment in substantia nigra reticulata is critical for the expression and control of hypoglycemia-induced seizures. J Neurosci (2008) 0.82
Chronic hypoperfusion alters the content and structure of proteins and lipids of rat brain homogenates: a Fourier transform infrared spectroscopy study. Eur Biophys J (2004) 0.81
Fasting-induced suppression of LH secretion does not require activation of ATP-sensitive potassium channels. Am J Physiol Endocrinol Metab (2008) 0.80
Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disorders. J Physiol Sci (2016) 0.79
Mechanism of KATP hyperactivity and sulfonylurea tolerance due to a diabetogenic mutation in L0 helix of sulfonylurea receptor 1 (ABCC8). FEBS Lett (2011) 0.79
Pancreatic beta-cell signaling: toward better understanding of diabetes and its treatment. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.79
Complex Membrane Channel Blockade: A Unifying Hypothesis for the Prodromal and Acute Neuropsychiatric Sequelae Resulting from Exposure to the Antimalarial Drug Mefloquine. J Parasitol Res (2015) 0.79
The effects of levosimendan on brain metabolism during initial recovery from global transient ischaemia/hypoxia. BMC Neurol (2012) 0.79
Noble gas xenon is a novel adenosine triphosphate-sensitive potassium channel opener. Anesthesiology (2010) 0.79
Progesterone reverses the neuronal responses to hypoxia in rat nucleus tractus solitarius in vitro. J Physiol (2002) 0.78
Effect of potassium channel modulators on morphine withdrawal in mice. Subst Abuse (2010) 0.78
Opening of astrocytic mitochondrial ATP-sensitive potassium channels upregulates electrical coupling between hippocampal astrocytes in rat brain slices. PLoS One (2013) 0.78
The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons. Elife (2016) 0.78
Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K⁺ (Kir2.1) channel. Pflugers Arch (2014) 0.77
Heterogeneous distribution of kir3 potassium channel proteins within dopaminergic neurons in the mesencephalon of the rat brain. Cell Mol Neurobiol (2007) 0.77
Targeting microglial K(ATP) channels to treat neurodegenerative diseases: a mitochondrial issue. Oxid Med Cell Longev (2013) 0.77
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A review of pioglitazone HCL and glimepiride in the treatment of type 2 diabetes. Vasc Health Risk Manag (2007) 0.76
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Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential. Front Physiol (2015) 0.75
BK channels reveal novel phosphate sensitivity in SNr neurons. PLoS One (2012) 0.75
Pregabalin attenuates excitotoxicity in diabetes. PLoS One (2013) 0.75
KATP channels modulate intrinsic firing activity of immature entorhinal cortex layer III neurons. Front Cell Neurosci (2014) 0.75
Heterogeneous responses to antioxidants in noradrenergic neurons of the Locus coeruleus indicate differing susceptibility to free radical content. Oxid Med Cell Longev (2012) 0.75
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Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse. Front Neuroanat (2017) 0.75
KATP Channel Mutations and Neonatal Diabetes. Intern Med (2017) 0.75
Molecular Bases of Brain Preconditioning. Front Neurosci (2017) 0.75
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