Published in Neuron on December 01, 2000
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol (2005) 9.12
Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron (2011) 8.06
miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat Neurosci (2009) 5.27
TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer (2010) 5.27
Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell (2008) 4.90
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell (2008) 3.87
Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal. Nature (2010) 3.54
TGF-β and BMP signaling in osteoblast differentiation and bone formation. Int J Biol Sci (2012) 3.49
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain. Development (2004) 3.30
Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling. Cell Stem Cell (2010) 2.85
PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas. Cancer Cell (2010) 2.68
In vivo reprogramming of astrocytes to neuroblasts in the adult brain. Nat Cell Biol (2013) 2.56
The stem cell potential of glia: lessons from reactive gliosis. Nat Rev Neurosci (2011) 2.49
Lake-front property: a unique germinal niche by the lateral ventricles of the adult brain. Neuron (2011) 2.14
Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair. Proc Natl Acad Sci U S A (2005) 2.09
Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell (2006) 2.06
IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. J Cell Biol (2004) 2.02
Development of neural stem cell in the adult brain. Curr Opin Neurobiol (2008) 2.02
BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci U S A (2001) 2.01
Adult neural stem cells bridge their niche. Cell Stem Cell (2012) 1.97
Brain micro-ecologies: neural stem cell niches in the adult mammalian brain. Philos Trans R Soc Lond B Biol Sci (2008) 1.91
GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice. Cell Stem Cell (2009) 1.84
Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile. Mol Cancer (2008) 1.72
Neural regeneration and cell replacement: a view from the eye. Cell Stem Cell (2008) 1.61
FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain. Development (2009) 1.55
Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later. Cell Stem Cell (2015) 1.54
S100B expression defines a state in which GFAP-expressing cells lose their neural stem cell potential and acquire a more mature developmental stage. Glia (2007) 1.54
Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells. PLoS Biol (2015) 1.51
Signaling mechanisms regulating adult neural stem cells and neurogenesis. Biochim Biophys Acta (2012) 1.50
Noggin expands neural stem cells in the adult hippocampus. J Neurosci (2008) 1.49
Molecular Identity of Human Outer Radial Glia during Cortical Development. Cell (2015) 1.49
The BMP ligand Gbb gates the expression of synaptic homeostasis independent of synaptic growth control. Neuron (2007) 1.48
Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons. PLoS One (2007) 1.45
Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injury. J Neurosci (2009) 1.45
Identification of a Chr 11 quantitative trait locus that modulates proliferation in the rostral migratory stream of the adult mouse brain. Eur J Neurosci (2010) 1.42
Orchestrating transcriptional control of adult neurogenesis. Genes Dev (2012) 1.41
Purinergic signaling regulates neural progenitor cell expansion and neurogenesis. Dev Biol (2006) 1.41
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proc Natl Acad Sci U S A (2004) 1.40
Ischemic stroke and neurogenesis in the subventricular zone. Neuropharmacology (2008) 1.39
Proliferation, neurogenesis and regeneration in the non-mammalian vertebrate brain. Philos Trans R Soc Lond B Biol Sci (2008) 1.38
Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet (2012) 1.37
Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals. J Neurosci (2010) 1.36
VEGF is a chemoattractant for FGF-2-stimulated neural progenitors. J Cell Biol (2003) 1.34
Adult neural stem cells stake their ground. Trends Neurosci (2014) 1.30
Cell cycle and lineage progression of neural progenitors in the ventricular-subventricular zones of adult mice. Proc Natl Acad Sci U S A (2013) 1.28
Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats. J Neurosci (2008) 1.27
Perivascular instruction of cell genesis and fate in the adult brain. Nat Neurosci (2011) 1.27
Neurogenesis in the embryonic and adult brain: same regulators, different roles. Front Cell Neurosci (2014) 1.25
Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease. J Clin Invest (2007) 1.25
Immune regulatory neural stem/precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function. PLoS One (2009) 1.21
APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis. Brain Struct Funct (2009) 1.20
A symphony of signals conducts early and late stages of adult neurogenesis. Neuropharmacology (2010) 1.20
Enhanced gene activation by Notch and BMP signaling cross-talk. Nucleic Acids Res (2003) 1.20
EphB signaling controls lineage plasticity of adult neural stem cell niche cells. Cell Stem Cell (2010) 1.17
Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain. Front Cell Neurosci (2013) 1.17
BMP-2 decreases Mash1 stability by increasing Id1 expression. EMBO J (2004) 1.16
Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system. Proc Natl Acad Sci U S A (2008) 1.16
BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice. PLoS One (2009) 1.14
Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers. Proc Natl Acad Sci U S A (2011) 1.14
Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors. PLoS One (2014) 1.13
A small molecule accelerates neuronal differentiation in the adult rat. Proc Natl Acad Sci U S A (2010) 1.12
Purification of immature neuronal cells from neural stem cell progeny. PLoS One (2011) 1.11
Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. PLoS One (2008) 1.10
The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation. Dev Neurobiol (2012) 1.10
Specification of a Foxj1-dependent lineage in the forebrain is required for embryonic-to-postnatal transition of neurogenesis in the olfactory bulb. J Neurosci (2011) 1.10
Diverse roles of the vasculature within the neural stem cell niche. Regen Med (2009) 1.09
It takes a village: constructing the neurogenic niche. Dev Cell (2015) 1.08
Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells. J Cell Sci (2011) 1.07
Cortical glial fibrillary acidic protein-positive cells generate neurons after perinatal hypoxic injury. J Neurosci (2011) 1.07
Bone marrow stromal cells induce BMP2/4 production in oxygen-glucose-deprived astrocytes, which promotes an astrocytic phenotype in adult subventricular progenitor cells. J Neurosci Res (2006) 1.05
Prospective identification, isolation, and profiling of a telomerase-expressing subpopulation of human neural stem cells, using sox2 enhancer-directed fluorescence-activated cell sorting. J Neurosci (2010) 1.05
RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. Neuron (2011) 1.05
Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches. BMB Rep (2009) 1.04
The path from the choroid plexus to the subventricular zone: go with the flow! Front Cell Neurosci (2012) 1.03
Tumor initiating cells in malignant gliomas: biology and implications for therapy. J Mol Med (Berl) (2009) 1.01
TGF-β family signaling in stem cells. Biochim Biophys Acta (2012) 1.01
Neural stem cells and the regulation of adult neurogenesis. Reprod Biol Endocrinol (2003) 1.00
Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications. Clin Cancer Res (2009) 1.00
Epimorphin expression in intestinal myofibroblasts induces epithelial morphogenesis. J Clin Invest (2002) 0.99
The regulation of the CNS innate immune response is vital for the restoration of tissue homeostasis (repair) after acute brain injury: a brief review. Int J Inflam (2010) 0.99
Epigenetic factors and cardiac development. Cardiovasc Res (2011) 0.97
The molecular profiles of neural stem cell niche in the adult subventricular zone. PLoS One (2012) 0.97
TGF-β superfamily gene expression and induction of the Runx1 transcription factor in adult neurogenic regions after brain injury. PLoS One (2013) 0.97
Cellular therapy and induced neuronal replacement for Huntington's disease. Neurotherapeutics (2011) 0.97
Genetic methods to identify and manipulate newly born neurons in the adult brain. Front Neurosci (2011) 0.97
Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nat Commun (2013) 0.96
Transcriptional repression of Bmp2 by p21(Waf1/Cip1) links quiescence to neural stem cell maintenance. Nat Neurosci (2013) 0.96
Anatomical perspectives on adult neural stem cells. J Anat (2005) 0.96
Activin A is essential for neurogenesis following neurodegeneration. Stem Cells (2009) 0.96
Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF. Gene Ther (2011) 0.95
Concise review: Quiescent and active states of endogenous adult neural stem cells: identification and characterization. Stem Cells (2011) 0.93
Ependymal cells along the lateral ventricle express functional P2X(7) receptors. Purinergic Signal (2009) 0.93
The generation of oligodendroglial cells is preserved in the rostral migratory stream during aging. Front Cell Neurosci (2013) 0.93
MHC mismatch inhibits neurogenesis and neuron maturation in stem cell allografts. PLoS One (2011) 0.93
Mesenchymal stem cells from human fat engineered to secrete BMP4 are nononcogenic, suppress brain cancer, and prolong survival. Clin Cancer Res (2014) 0.93
Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease. Neurol Res Int (2011) 0.92
Future of cell and gene therapies for Parkinson's disease. Ann Neurol (2008) 0.92
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell (1999) 15.87
Long-distance neuronal migration in the adult mammalian brain. Science (1994) 8.02
Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci (1997) 6.74
Astrocytes give rise to new neurons in the adult mammalian hippocampus. J Neurosci (2001) 5.66
Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. Proc Natl Acad Sci U S A (1993) 5.00
Chain migration of neuronal precursors. Science (1996) 4.79
A unified hypothesis on the lineage of neural stem cells. Nat Rev Neurosci (2001) 3.86
Regeneration of a germinal layer in the adult mammalian brain. Proc Natl Acad Sci U S A (1999) 3.53
In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain. Development (2001) 3.35
Network of tangential pathways for neuronal migration in adult mammalian brain. Proc Natl Acad Sci U S A (1996) 3.14
Young neurons from medial ganglionic eminence disperse in adult and embryonic brain. Nat Neurosci (1999) 2.92
Direct evidence for homotypic, glia-independent neuronal migration. Neuron (1997) 2.53
Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone. Nat Neurosci (2000) 2.45
Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool. Dev Biol (2008) 2.38
Stem cells in the adult mammalian central nervous system. Curr Opin Neurobiol (1999) 2.16
Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc Natl Acad Sci U S A (1999) 1.90
Architecture and cell types of the adult subventricular zone: in search of the stem cells. J Neurobiol (1998) 1.90
Embryonic (PSA) N-CAM reveals chains of migrating neuroblasts between the lateral ventricle and the olfactory bulb of adult mice. J Comp Neurol (1995) 1.55
BDNF mediates the effects of testosterone on the survival of new neurons in an adult brain. Neuron (1999) 1.44
Testosterone increases the recruitment and/or survival of new high vocal center neurons in adult female canaries. Proc Natl Acad Sci U S A (1994) 1.28
The subventricular zone: source of neuronal precursors for brain repair. Prog Brain Res (2000) 1.26
IGF-I stimulates neurogenesis in the hypothalamus of adult rats. Eur J Neurosci (2010) 1.26
Composition and organization of the SCZ: a large germinal layer containing neural stem cells in the adult mammalian brain. Cereb Cortex (2006) 1.26
Fate of new neurons in adult canary high vocal center during the first 30 days after their formation. J Comp Neurol (1999) 1.24
Primary neural precursors and intermitotic nuclear migration in the ventricular zone of adult canaries. J Neurosci (1998) 1.23
Adult subventricular zone neuronal precursors continue to proliferate and migrate in the absence of the olfactory bulb. J Neurosci (1999) 1.18
Differential developmental expression of cellular yes and cellular src proteins in cerebellum. Oncogene Res (1988) 1.18
Adult-derived neural precursors transplanted into multiple regions in the adult brain. Ann Neurol (1999) 1.17
Song learning in birds: the relation between perception and production. Philos Trans R Soc Lond B Biol Sci (1990) 1.14
Unsupervised learning and adaptation in a model of adult neurogenesis. J Comput Neurosci (2001) 1.09
Acute and chronic effects of an aromatase inhibitor on territorial aggression in breeding and nonbreeding male song sparrows. J Comp Physiol A (2001) 1.09
Oestrogen regulates male aggression in the non-breeding season. Proc Biol Sci (2000) 1.05
Production and survival of projection neurons in a forebrain vocal center of adult male canaries. J Neurosci (1991) 1.05
Modulation of adult hippocampal neurogenesis by thyroid hormones: implications in depressive-like behavior. Mol Psychiatry (2006) 1.03
Chronic cocaine exposure impairs progenitor proliferation but spares survival and maturation of neural precursors in adult rat dentate gyrus. Eur J Neurosci (2006) 1.02
Neurogenesis and neuronal regeneration in the adult reptilian brain. Brain Behav Evol (2001) 0.99
The life span of new neurons in a song control nucleus of the adult canary brain depends on time of year when these cells are born. Proc Natl Acad Sci U S A (1994) 0.99
Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain. Proc Natl Acad Sci U S A (1996) 0.98
Environmental enrichment reduces the function of D1 dopamine receptors in the prefrontal cortex of the rat. J Neural Transm (Vienna) (2006) 0.97
Postnatal mouse subventricular zone neuronal precursors can migrate and differentiate within multiple levels of the developing neuraxis. Proc Natl Acad Sci U S A (1997) 0.97
Morphological aspects of the ectopic granule-like cellular populations in the albino rat hippocampal formation: a Golgi study. J Anat (1986) 0.93
On variables that affect estimates of the true sizes and densities of radioactively labeled cell nuclei. J Comp Neurol (1990) 0.93
Functional neural stem cells derived from adult bone marrow. Neuroscience (2005) 0.93
Pituitary and adrenals are required for hyperglycemic reflex initiated by stimulation of CBR with cyanide. Am J Physiol (1997) 0.91
3-Acetylpyridine-induced degeneration and regeneration in the adult lizard brain: a qualitative and quantitative analysis. Brain Res (1997) 0.89
Neurogenesis in juvenile and adult ring doves. J Comp Neurol (1997) 0.89
L-dopa activates c-fos in the striatum ipsilateral to a 6-hydroxydopamine lesion of the substantia nigra. Eur J Pharmacol (1989) 0.87
Adult neurogenesis in the telencephalon of a lizard: a [3H]thymidine autoradiographic and bromodeoxyuridine immunocytochemical study. Brain Res Dev Brain Res (1996) 0.85
Mouse primordial germ cells use fibronectin as a substrate for migration. Exp Cell Res (1986) 0.84
Hippocampal volume does not change seasonally in a non food-storing songbird. Neuroreport (2001) 0.84
Neoangiogenesis with endothelial precursors for the treatment of ischemia. Transplant Proc (2007) 0.83
Production of plasminogen activator in cultures of superior cervical ganglia and isolated Schwann cells. Proc Natl Acad Sci U S A (1985) 0.83
Binge administration of 3,4-methylenedioxymethamphetamine ("ecstasy") impairs the survival of neural precursors in adult rat dentate gyrus. Neuropharmacology (2006) 0.82
Seasonal differences in ventricular proliferation of adult Gallotia galloti lizards. Brain Res (2007) 0.80
Postnatal neurogenesis in the telencephalon of turtles: evidence for nonradial migration of new neurons from distant proliferative ventricular zones to the olfactory bulbs. Brain Res Dev Brain Res (1997) 0.79
Lesion and regeneration in the medial cerebral cortex of lizards. Histol Histopathol (1992) 0.78
Characterization of alkaline phosphatase from primordial germ cells and ontogenesis of this enzyme in the mouse. Differentiation (1985) 0.78
Neuron regeneration reverses 3-acetylpyridine-induced cell loss in the cerebral cortex of adult lizards. Brain Res (1991) 0.77
In situ hybridization using PEG-embedded tissue and riboprobes: increased cellular detail coupled with high sensitivity. J Histochem Cytochem (1989) 0.77
Adult-onset Krabbe's disease in siblings with novel mutations in the galactocerebrosidase gene. Ann Neurol (1997) 0.76
Study of adult neurogenesis in the Gallotia galloti lizard during different seasons. Brain Res (2011) 0.76
Olfacto-retinalis pathway in Austrolebias charrua fishes: a neuronal tracer study. Neuroscience (2013) 0.76
Expression of the yes proto-oncogene in cerebellar Purkinje cells. Mol Cell Biol (1989) 0.76
[Cellular therapy in amyotrophic lateral sclerosis]. Neurologia (2008) 0.75
Distribution of basal-expressed c-fos-like immunoreactive cells of the periaqueductal grey matter of the rat. Neuroreport (1996) 0.75
Trigeminal projections to the dorsal thalamus in a lacertid lizard, Podarcis hispanica. Brain Behav Evol (1998) 0.75
[Organization of the Septum of reptiles (Podarcis pityusensis, Lacertidae). A volumetric and Golgi method study]. Trab Inst Cajal (1981) 0.75
A Golgi and electron microscope study of the precommissural dorsal septum in the reptile: Podarcis hispanica. Anat Anz (1988) 0.75
[Experimental models of amyotrophic lateral sclerosis]. Neurologia (2007) 0.75