Published in Gene Ther on September 15, 2011
The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation. Dev Neurobiol (2012) 1.10
Biology of adeno-associated viral vectors in the central nervous system. Front Mol Neurosci (2014) 1.04
Gene therapy for the nervous system: challenges and new strategies. Neurotherapeutics (2014) 0.98
Cellular therapy and induced neuronal replacement for Huntington's disease. Neurotherapeutics (2011) 0.97
Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease. Cell Stem Cell (2013) 0.91
Mechanisms of RNA-induced toxicity in CAG repeat disorders. Cell Death Dis (2013) 0.91
A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone. J Neurosci (2015) 0.84
Targeted gene transfer into ependymal cells through intraventricular injection of AAV1 vector and long-term enzyme replacement via the CSF. Sci Rep (2014) 0.83
Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons. EMBO Mol Med (2014) 0.82
BMP signaling in telencephalic neural cell specification and maturation. Front Cell Neurosci (2013) 0.80
Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models. Mol Ther (2016) 0.79
Use of Genetically Altered Stem Cells for the Treatment of Huntington's Disease. Brain Sci (2014) 0.78
Striatal oligodendrogliogenesis and neuroblast recruitment are increased in the R6/2 mouse model of Huntington's disease. Brain Res (2013) 0.77
Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington's disease is accompanied by striatal invasion of neuroblasts. PLoS One (2015) 0.77
Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells. Neural Regen Res (2016) 0.76
The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease. Mol Med (2017) 0.75
Increased Olfactory Bulb BDNF Expression Does Not Rescue Deficits in Olfactory Neurogenesis in the Huntington's Disease R6/2 Mouse. Chem Senses (2016) 0.75
Over-Expression of Meteorin Drives Gliogenesis Following Striatal Injury. Front Cell Neurosci (2016) 0.75
Hippocampal bone morphogenetic protein signaling mediates behavioral effects of antidepressant treatment. Mol Psychiatry (2016) 0.75
Identification, cloning, and functional analysis of the TATA-less mouse FNDC5 promoter during neural differentiation. Cell Mol Neurobiol (2014) 0.75
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell (1999) 15.87
Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med (2002) 10.10
Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci (1990) 8.61
Long-distance neuronal migration in the adult mammalian brain. Science (1994) 8.02
Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron (1993) 6.07
Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron (1999) 5.59
Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension. Science (2007) 5.23
Induction of neurogenesis in the neocortex of adult mice. Nature (2000) 5.04
Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell (2002) 4.87
Adeno-associated virus serotypes: vector toolkit for human gene therapy. Mol Ther (2006) 4.36
Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron (2000) 4.18
Rat forebrain neurogenesis and striatal neuron replacement after focal stroke. Ann Neurol (2002) 4.07
Insect cells as a factory to produce adeno-associated virus type 2 vectors. Hum Gene Ther (2002) 3.92
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci U S A (1995) 3.90
Gene therapy using adeno-associated virus vectors. Clin Microbiol Rev (2008) 3.30
Maturation and death of adult-born olfactory bulb granule neurons: role of olfaction. J Neurosci (2002) 3.28
Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus. J Neurosci (2001) 3.23
Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles. J Virol (1997) 2.91
Enriched odor exposure increases the number of newborn neurons in the adult olfactory bulb and improves odor memory. J Neurosci (2002) 2.53
Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells. J Comp Neurol (2006) 2.53
Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC. Mol Ther (2006) 2.41
Integration of adeno-associated virus (AAV) and recombinant AAV vectors. Annu Rev Genet (2004) 2.36
NeuN: a useful neuronal marker for diagnostic histopathology. J Histochem Cytochem (1996) 2.29
Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain. Neurosci Lett (2000) 2.22
The generation, migration, and differentiation of olfactory neurons in the adult primate brain. Proc Natl Acad Sci U S A (2001) 2.05
Recombinant AAV-mediated gene delivery to the central nervous system. J Gene Med (2004) 1.94
Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain. J Neurosci (2001) 1.94
Fluorescent latex microspheres as a retrograde neuronal marker for in vivo and in vitro studies of visual cortex. Nature (1984) 1.85
Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment. Dev Biol (2003) 1.75
Learning and survival of newly generated neurons: when time matters. J Neurosci (2008) 1.70
A progressive and cell non-autonomous increase in striatal neural stem cells in the Huntington's disease R6/2 mouse. J Neurosci (2006) 1.64
Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb. Mol Cell Neurosci (1998) 1.61
Adeno-associated virus: from defective virus to effective vector. Virol J (2005) 1.60
Characterization of posttranslational modifications in neuron-specific class III beta-tubulin by mass spectrometry. Proc Natl Acad Sci U S A (1991) 1.57
Critical period for sensory experience-dependent survival of newly generated granule cells in the adult mouse olfactory bulb. Proc Natl Acad Sci U S A (2005) 1.57
Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors. J Neurosci (2005) 1.56
Comment on "Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension". Science (2007) 1.52
FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease. Proc Natl Acad Sci U S A (2005) 1.46
Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients. J Biol Chem (2001) 1.43
Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells. Ann Neurol (1998) 1.32
Adenovirally expressed noggin and brain-derived neurotrophic factor cooperate to induce new medium spiny neurons from resident progenitor cells in the adult striatal ventricular zone. J Neurosci (2004) 1.30
Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats. J Neurosci (2008) 1.27
Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease. Neuroscience (2004) 1.27
Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease. J Clin Invest (2007) 1.25
Strategies utilized by migrating neurons of the postnatal vertebrate forebrain. Trends Neurosci (1998) 1.23
Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone. J Neurosci Res (2000) 1.18
Adeno-associated virus type 4 (AAV4) targets ependyma and astrocytes in the subventricular zone and RMS. Gene Ther (2005) 1.14
Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment. J Neurosci (2005) 1.12
Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's disease. Neuroscience (1995) 1.07
Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy. Hum Mol Genet (2005) 1.01
Noninvasive and quantitative monitoring of adult neuronal stem cell migration in mouse brain using bioluminescence imaging. Stem Cells (2008) 0.99
AAV-mediated delivery of BDNF augments neurogenesis in the normal and quinolinic acid-lesioned adult rat brain. Eur J Neurosci (2007) 0.98
Chemical characterization of newly generated neurons in the striatum of adult primates. Exp Brain Res (2005) 0.97
Huntington's disease and dentatorubral-pallidoluysian atrophy: proteins, pathogenesis and pathology. Brain Pathol (1997) 0.89
Transgenic models of Huntington's disease. Hum Mol Genet (1997) 0.89
Developmental regulation of phosphoprotein gene expression in the caudate-putamen of rat: an in situ hybridization study. Neuroscience (1992) 0.79
Astrocyte-mediated potentiation of inhibitory synaptic transmission. Nat Neurosci (1998) 4.20
In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nat Med (2000) 4.18
The interpretation of random-effects meta-analysis in decision models. Med Decis Making (2005) 3.98
Neural induction by the secreted polypeptide noggin. Science (1993) 3.45
Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain. Proc Natl Acad Sci U S A (1983) 3.05
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell (1998) 2.89
Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Mol Cell Neurosci (2001) 2.47
Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly. Structure (1996) 2.46
The incidence and risk of central venous catheter malpositioning: a prospective cohort study in 1619 patients. Anaesth Intensive Care (2008) 2.31
Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma. Mol Cell Neurosci (1999) 2.30
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. Genome Res (2000) 2.21
The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry. Nature (1999) 2.08
Expected value of sample information calculations in medical decision modeling. Med Decis Making (2004) 2.04
Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin. J Bone Miner Res (2000) 2.03
Electron cryomicroscopy and bioinformatics suggest protein fold models for rice dwarf virus. Nat Struct Biol (2001) 1.99
The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb. Development (1999) 1.96
Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain. J Neurosci (2001) 1.94
A maize protein associated with the G-box binding complex has homology to brain regulatory proteins. Plant Cell (1992) 1.85
Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. Proc Natl Acad Sci U S A (2001) 1.84
Identification of mammalian noggin and its expression in the adult nervous system. J Neurosci (1995) 1.81
High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain. Nat Biotechnol (2001) 1.72
Structure of Semliki Forest virus core protein. Proteins (1997) 1.70
Identification, isolation, and promoter-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter. J Neurosci (1999) 1.68
Ulcerative colitis has an aggressive course after orthotopic liver transplantation for primary sclerosing cholangitis. Gut (1998) 1.63
Skeletal overexpression of noggin results in osteopenia and reduced bone formation. Endocrinology (2003) 1.60
Connective tissue growth factor promotes fibrosis downstream of TGFbeta and IL-6 in chronic cardiac allograft rejection. Am J Transplant (2009) 1.59
In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain. Cereb Cortex (1995) 1.57
Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features. Leukemia (2010) 1.51
Hu protein as an early marker of neuronal phenotypic differentiation by subependymal zone cells of the adult songbird forebrain. J Neurobiol (1995) 1.50
Small hepatocellular carcinomas in cirrhotic explant livers: identification by macroscopic examination and lipiodol localization. Hepatology (1997) 1.48
The circular dichroism of the beta structure of poly-L-lysine. Biochem Biophys Res Commun (1966) 1.48
The effect of anesthesia type on needle localization breast biopsy: another point of view. Am J Surg (1996) 1.45
Brain-derived neurotrophic factor promotes the survival of neurons arising from the adult rat forebrain subependymal zone. Proc Natl Acad Sci U S A (1995) 1.44
Treatment of acute gastroenteritis: too much and too little care. Clin Pediatr (Phila) (1996) 1.44
Systemic vasculitis with multiple aneurysms complicating systemic lupus erythematosus. J R Soc Med (1999) 1.41
High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases. J Biol Chem (1998) 1.41
Clinical evaluation of the Terry surgical keratometer. J Am Intraocul Implant Soc (1980) 1.40
The Shearing intraocular lens: a report of 1,000 cases. J Am Intraocul Implant Soc (1981) 1.40
Delayed diagnosis of biliary leak due to bile duct division during cholecystectomy. J R Coll Surg Edinb (1994) 1.37
Induction of IL-8 expression by human herpesvirus 8 encoded vFLIP K13 via NF-kappaB activation. Oncogene (2006) 1.33
Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells. Ann Neurol (1998) 1.32
Morphogenesis of digits in the avian limb is controlled by FGFs, TGFbetas, and noggin through BMP signaling. Dev Biol (1998) 1.32
Two-color labeling of oligonucleotide arrays via size-selective scattering of nanoparticle probes. J Am Chem Soc (2001) 1.31
The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form). J Mol Biol (1996) 1.30
Expression and function of Gdf-5 during digit skeletogenesis in the embryonic chick leg bud. Dev Biol (1999) 1.28
A recombinant bcl-x s adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells. Proc Natl Acad Sci U S A (1995) 1.25
Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci (2001) 1.25
Separation, properties, and regulation of acyl coenzyme A dehydrogenases from bovine heat and liver. Arch Biochem Biophys (1982) 1.24
Acid-induced death in neurons and glia. J Neurosci (1991) 1.22
Kinetics and mechanism of bacterial disinfection by chlorine dioxide. Appl Microbiol (1967) 1.18
Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone. J Neurosci Res (2000) 1.18
Oleic acid inhibits endothelial nitric oxide synthase by a protein kinase C-independent mechanism. Hypertension (1995) 1.16
Two broad-spectrum blast resistance genes, Pi9( t) and Pi2( t), are physically linked on rice chromosome 6. Mol Genet Genomics (2002) 1.16
Evolutionary implications of the family of 14-3-3 brain protein homologs in Arabidopsis thaliana. Genetica (1994) 1.15
Carrier-mediated transport of lactic acid in cultured neurons and astrocytes. Am J Physiol (1993) 1.14
Human disease-causing NOG missense mutations: effects on noggin secretion, dimer formation, and bone morphogenetic protein binding. Proc Natl Acad Sci U S A (2001) 1.14
Stretch-induced MAP kinase activation in cardiac myocytes: differential regulation through beta1-integrin and focal adhesion kinase. J Mol Cell Cardiol (2007) 1.14
Upregulation of vascular endothelial growth factor is associated with radiation-induced blood-spinal cord barrier breakdown. J Neuropathol Exp Neurol (1999) 1.13
Critical role for IL-6 in hypertrophy and fibrosis in chronic cardiac allograft rejection. Am J Transplant (2009) 1.13
A prospective controlled study comparing brush and bile exfoliative cytology for diagnosing bile duct strictures. Gut (1992) 1.10
Expression of BMP-7 and USAG-1 (a BMP antagonist) in kidney development and injury. Kidney Int (2007) 1.10
Progranulin expression in the developing and adult murine brain. J Comp Neurol (2010) 1.09
The conformational transitions of uncharged poly-L-lysine. Alpha helix-random coil-beta structure. Biochemistry (1967) 1.09
Low molecular weight heparin: a critical analysis of clinical trials. Pharmacol Rev (1994) 1.08
Endothelial cell loss following phacoemulsification in the pupillary plane. J Am Intraocul Implant Soc (1981) 1.07
Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters. J Neurosci Res (2001) 1.07
Highly enriched cardiomyocytes from human embryonic stem cells. Cytotherapy (2008) 1.07
The bone morphogenetic proteins antagonist Noggin inhibits membranous ossification. J Bone Miner Res (2001) 1.06
Sustainable veterinary medicine for the new era. Rev Sci Tech (2003) 1.06
Yellow jacket venom allergens, hyaluronidase and phospholipase: sequence similarity and antigenic cross-reactivity with their hornet and wasp homologs and possible implications for clinical allergy. J Allergy Clin Immunol (1996) 1.06
Bone morphogenetic proteins induce gremlin, a protein that limits their activity in osteoblasts. Endocrinology (2000) 1.05
The use of computed optical rotatory dispersion curves for the evaluation of protein conformation. Biochemistry (1967) 1.05
Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4. J Biol Chem (1998) 1.05
Gap junctions are required for the propagation of spreading depression. J Neurobiol (1995) 1.03
Posterior chamber intraocular lens power calculation in 441 cases. J Am Intraocul Implant Soc (1979) 1.03
The heterologous interactions among plant 14-3-3 proteins and identification of regions that are important for dimerization. Arch Biochem Biophys (1997) 1.03
Influence of myocardial infarction, coronary artery bypass surgery, and stroke on cognitive impairment in late life. Am J Cardiol (1998) 1.02
Endoscopic sphenopalatine artery ligation is an effective method of treatment for posterior epistaxis. Am J Rhinol (1999) 1.00
Glutamic acid residue 98 is critical for catalysis in pig kidney fructose-1,6-bisphosphatase. Biochem Biophys Res Commun (1996) 1.00
An innovative method for counting females of soybean cyst nematode with fluorescence imaging technology. J Nematol (2005) 1.00
Case report: hepatic and retro-peritoneal endometriosis presenting as obstructive jaundice with ascites: a case report and review of the literature. Clin Radiol (2002) 0.99
N-cadherin and Ng-CAM/8D9 are involved serially in the migration of newly generated neurons into the adult songbird brain. Neuron (1994) 0.98
Efficacy of glucose-based oral rehydration therapy. Pediatrics (1996) 0.98
Colonic spirochetosis of colony-raised rhesus macaques associated with Brachyspira and Helicobacter. Anaerobe (2003) 0.97
Sydenham's chorea and seizures. Clinical and electroencephalographic studies. Arch Neurol (1978) 0.97
The Terry surgical keratometer: a 12-month follow-up report. J Am Intraocul Implant Soc (1981) 0.96
Biliary anastomosis after liver transplantation does not benefit from T tube splintage. Transplantation (1994) 0.96
Population-based, case-control study of blood C-peptide level and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2001) 0.96
Control of digit formation by activin signalling. Development (1999) 0.95
The Hera database and its use in the characterization of endoplasmic reticulum proteins. Bioinformatics (2004) 0.95
Portal vein embolisation prior to hepatic resection for colorectal liver metastases and the effects of periprocedure chemotherapy. Br J Radiol (2006) 0.95
Neural stem and progenitor cells: a strategy for gene therapy and brain repair. Neurosurgery (1998) 0.94
Meningeal cells can communicate with astrocytes by calcium signaling. Ann Neurol (2000) 0.94
Rates of Jewish ancestral mutations in BRCA1 and BRCA2 in borderline ovarian tumors. J Natl Cancer Inst (1998) 0.94
Responding to hypoxia: lessons from a model cell line. Sci STKE (2002) 0.94
Isolation of neuronal precursors by sorting embryonic forebrain transfected with GFP regulated by the T alpha 1 tubulin promoter. Nat Biotechnol (1998) 0.94
The effect of the illness episode approach on Medicare beneficiaries' health insurance decisions. Health Serv Res (1992) 0.94
Mixed treatment comparison with multiple outcomes reported inconsistently across trials: evaluation of antivirals for treatment of influenza A and B. Stat Med (2008) 0.93
Squamous cell carcinoma as a late complication of intracerebroventricular epidermoid cyst. Case report. J Neurosurg (1987) 0.93