Published in Hepatology on February 01, 2001
Interference of hepatitis C virus RNA replication by short interfering RNAs. Proc Natl Acad Sci U S A (2003) 2.64
Hepatitis C: a review for primary care physicians. CMAJ (2006) 1.60
Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment. J Transl Med (2008) 1.11
Evaluation of Different Strategies for Post-Exposure Treatment of Ebola Virus Infection in Rodents. J Bioterror Biodef (2011) 1.09
Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: a nonhormonal contraceptive strategy. Proc Natl Acad Sci U S A (2007) 1.03
Factors affecting serum concentrations of hepatitis C virus (HCV) RNA in HCV genotype 1-infected patients with chronic hepatitis. J Clin Microbiol (2007) 1.00
Safety, tolerability and efficacy of peginterferon alpha-2a and ribavirin in chronic hepatitis C in clinical practice: The German Open Safety Trial. J Viral Hepat (2007) 0.96
Sustained viral response to pegylated interferon alpha-2b and ribavirin in chronic hepatitis C refractory to prior treatment. Dig Dis Sci (2006) 0.95
IL11 antagonist inhibits uterine stromal differentiation, causing pregnancy failure in mice. Biol Reprod (2009) 0.95
Hepatitis C virus infection and mixed cryoglobulinemia. Clin Dev Immunol (2012) 0.94
Chronic hepatitis C. Gut Liver (2011) 0.94
Drug delivery strategies for therapeutic angiogenesis and antiangiogenesis. Expert Opin Drug Deliv (2011) 0.92
Treatment of chronic hepatitis. BMJ (2001) 0.92
Hepatitis C-Z: recent advances. Arch Dis Child (2002) 0.88
Effects of a 24-week course of interferon-alpha therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma. World J Gastroenterol (2007) 0.87
Comparison of adverse effects related to pegylated interferon-based therapy for patients with chronic hepatitis B and chronic hepatitis C in Taiwan. Hepatol Int (2010) 0.82
Evolution of interferon-based therapy for chronic hepatitis C. Hepat Res Treat (2010) 0.79
Immunocytokines: a novel class of products for the treatment of chronic inflammation and autoimmune conditions. Drug Discov Today (2015) 0.79
Influence of IL28B polymorphisms on response to a lower-than-standard dose peg-IFN-α 2a for genotype 3 chronic hepatitis C in HIV-coinfected patients. PLoS One (2012) 0.79
Cost-effectiveness analysis of adding low dose ribavirin to peginterferon alfa-2a for treatment of chronic hepatitis C infected thalassemia major patients in iran. Hepat Mon (2013) 0.78
PEGylated interferon beta-1a in the treatment of multiple sclerosis - an update. Biologics (2013) 0.78
Improvement in quality of life measures in patients with refractory hepatitis C, responding to re-treatment with Pegylated interferon alpha -2b and ribavirin. Health Qual Life Outcomes (2006) 0.78
Safety and Efficacy of Adding Ribavirin to Interferon or Peginterferon in Treatment of Hepatitis C Infection in Patients With Thalassemia: A Systematic Review on Randomized Controlled Trials. Hepat Mon (2016) 0.77
Nanomedicines in the treatment of chronic hepatitis C--focus on pegylated interferon alpha-2a. Int J Nanomedicine (2007) 0.77
Role of Sleep Disturbance in Chronic Hepatitis C Infection. Curr Hepat Rep (2010) 0.77
Low- and standard-dose peginterferon alfa-2a for chronic hepatitis C, genotype 2 or 3: efficacy, tolerability, viral kinetics and cytokine response. Aliment Pharmacol Ther (2010) 0.77
Is laparoscopy an advantage in the diagnosis of cirrhosis in chronic hepatitis C virus infection? World J Gastroenterol (2003) 0.77
Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic. Sci Rep (2016) 0.77
Triple antiviral therapy in HCV positive patients who failed prior combination therapy. World J Gastroenterol (2006) 0.76
Interactions between Hsp90 and oncogenic viruses: implications for viral cancer therapeutics. Am J Cancer Res (2011) 0.76
Interferon beta 1a versus interferon beta 1a plus ribavirin for the treatment of chronic hepatitis C in Chinese patients: a randomized, placebo-controlled trial. Dig Dis Sci (2007) 0.76
Antidepressant prophylaxis reduces depression risk but does not improve sustained virological response in hepatitis C interferon recipients without depression at baseline: a systematic review and meta-analysis. Can J Gastroenterol (2013) 0.75
Analysis of effect of antiviral therapy on regression of liver fibrosis in patient with HCV infection. Mater Sociomed (2014) 0.75
Effect of alpha 2b interferon on inducement of mIL-2R and treatment of HCV in PBMC from patients with chronic viral hepatitis C. World J Gastroenterol (2003) 0.75
Clinical experience with nonstandard doses ofinterferon alfa-2b and ribavirin in the treatment of chronic hepatitis C infection: A retrospective analysis. Curr Ther Res Clin Exp (2005) 0.75
New treatment strategies against hepatitis C viral infection. Can J Gastroenterol (2006) 0.75
Effect of pegylated interferon on non-responders and relapsers with interferon. J Sci Res Med Sci (2002) 0.75
Emerging therapies for chronic hepatitis C virus. Gastroenterol Hepatol (N Y) (2008) 0.75
A pharmacokinetic and pharmacodynamic comparison of a novel pegylated recombinant consensus interferon-α variant with peginterferon-α-2a in healthy subjects. Br J Clin Pharmacol (2015) 0.75
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet (2001) 35.17
Microbial complexes in subgingival plaque. J Clin Periodontol (1998) 15.90
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Engl J Med (1998) 14.40
Proposed uniform nomenclature for mammalian ribosomal proteins. Mol Gen Genet (1979) 13.52
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev (1993) 10.01
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med (1999) 9.78
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell (1995) 9.30
Imaging beta-amyloid burden in aging and dementia. Neurology (2007) 7.70
Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med (1996) 6.49
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci U S A (1991) 6.42
Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities. Proc Natl Acad Sci U S A (1986) 6.16
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science (1994) 6.07
Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med (1995) 5.98
Effect of total allelic relationship on accuracy of evaluation and response to selection. J Anim Sci (1997) 5.79
Peginterferon alfa-2a in patients with chronic hepatitis C. N Engl J Med (2000) 5.58
Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J Med (1999) 5.32
Inhibition of JNK activation through NF-kappaB target genes. Nature (2001) 5.03
A genomic screen of autism: evidence for a multilocus etiology. Am J Hum Genet (1999) 4.96
Acetaminophen toxicity in an urban county hospital. N Engl J Med (1997) 4.26
Sexual abuse in a national survey of adult men and women: prevalence, characteristics, and risk factors. Child Abuse Negl (1990) 3.96
Golgi tubule traffic and the effects of brefeldin A visualized in living cells. J Cell Biol (1997) 3.91
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci U S A (1999) 3.91
Evaluation of two school smoking education programmes under normal classroom conditions. BMJ (1993) 3.83
The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo. Cell (1996) 3.81
Chromosomal location of genes regulating resistance to bacteriophage in Bacillus subtilis. J Bacteriol (1969) 3.74
Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis. N Engl J Med (2000) 3.74
European S3-guidelines on the systemic treatment of psoriasis vulgaris. J Eur Acad Dermatol Venereol (2009) 3.56
Dynamics of Pleistocene population extinctions in Beringian brown bears. Science (2002) 3.53
Undergraduate research. Genomics Education Partnership. Science (2008) 3.45
"Occult" hepatitis B virus as source of infection in liver transplant recipients. Lancet (1994) 3.33
Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers. Proc Natl Acad Sci U S A (1999) 3.30
Identification of the human c-myc protein nuclear translocation signal. Mol Cell Biol (1988) 3.30
Molecular virology and pathogenesis of hepatitis B. Lancet (1993) 3.27
Discriminating between different modes of inheritance in genetic disease. Clin Genet (1971) 3.10
Training family doctors to recognise psychiatric illness with increased accuracy. Lancet (1980) 3.09
Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice. Genome Res (2001) 3.04
Women's health: potential for better coordination of services. Genitourin Med (1991) 2.99
Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins. J Biol Chem (1989) 2.89
Max: functional domains and interaction with c-Myc. Genes Dev (1992) 2.88
Charybdotoxin block of single Ca2+-activated K+ channels. Effects of channel gating, voltage, and ionic strength. J Gen Physiol (1988) 2.87
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Hepatic lidocaine metabolism and liver histology in patients with chronic hepatitis and cirrhosis. Hepatology (1994) 2.81
Revised clinical and laboratory criteria for subtypes of inherited epidermolysis bullosa. A consensus report by the Subcommittee on Diagnosis and Classification of the National Epidermolysis Bullosa Registry. J Am Acad Dermatol (1991) 2.79
Etiology and outcome for 295 patients with acute liver failure in the United States. Liver Transpl Surg (1999) 2.79
Health spending growth up in 1999; faster growth expected in the future. Health Aff (Millwood) (2001) 2.77
"Checkerboard" DNA-DNA hybridization. Biotechniques (1994) 2.70
Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein. Nature (1989) 2.70
The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine (1998) 2.70
c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF. Cell (1985) 2.69
A working formulation for the standardization of nomenclature and for clinical staging of chronic dysfunction in lung allografts. International Society for Heart and Lung Transplantation. J Heart Lung Transplant (1993) 2.69
Transjugular intrahepatic portosystemic shunts compared with endoscopic sclerotherapy for the prevention of recurrent variceal hemorrhage. A randomized, controlled trial. Ann Intern Med (1997) 2.69
Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J Clin Invest (1991) 2.65
Mixed infections with Opisthorchis viverrini and intestinal flukes in residents of Vientiane Municipality and Saravane Province in Laos. J Helminthol (2005) 2.62
Impaired sucrose-induction mutants reveal the modulation of sugar-induced starch biosynthetic gene expression by abscisic acid signalling. Plant J (2001) 2.61
HCV-related fibrosis progression following liver transplantation: increase in recent years. J Hepatol (2000) 2.60
Ribavirin as therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (1995) 2.49
Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes. Cancer Res (1991) 2.46
Concordance in twins: methods and interpretation. Am J Hum Genet (1974) 2.45
Fungal infections in patients with acute leukemia. Am J Med (1982) 2.43
Interaction between a "processed" ovalbumin peptide and Ia molecules. Proc Natl Acad Sci U S A (1986) 2.42
Heteroplasmic mtDNA mutation (T----G) at 8993 can cause Leigh disease when the percentage of abnormal mtDNA is high. Am J Hum Genet (1992) 2.41
c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol Cell Biol (1994) 2.41
Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. FEBS Lett (1998) 2.40
Targeting and function in mRNA export of nuclear pore complex protein Nup153. J Cell Biol (1996) 2.38
Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite. Arch Biochem Biophys (1992) 2.37
Heritability of liability and concordance in monozygous twins. Ann Hum Genet (1970) 2.35
Ascertainment and prevention of genetic disease. Br Med J (1970) 2.33
Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell (2001) 2.29
Comparison of rapid detection methods for influenza A virus and their value in health-care management of institutionalized geriatric patients. J Clin Microbiol (1994) 2.28
Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies. Leukemia (2007) 2.27
Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection. J Clin Invest (1999) 2.26
Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene. Proc Natl Acad Sci U S A (1991) 2.26
Colonic necrosis with Kayexalate-sorbitol enemas after renal transplantation. Ann Intern Med (1989) 2.24
The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. EMBO J (1996) 2.22
Why older patients of lower clinical urgency choose to attend the emergency department. Intern Med J (2013) 2.19
Experience-dependent changes in cerebral activation during human REM sleep. Nat Neurosci (2000) 2.18
A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharmacol Ther (2012) 2.12
TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia. J Neurol Neurosurg Psychiatry (2008) 2.07
An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface. J Cell Biol (1996) 2.06
Recurrence risks for multifactorial inheritance. Am J Hum Genet (1971) 2.06
Subgingival microbiota in healthy, well-maintained elder and periodontitis subjects. J Clin Periodontol (1998) 2.06
Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression. Proc Natl Acad Sci U S A (1986) 2.00
Source of prenatal care and infant birth weight: the case of a North Carolina county. Am J Obstet Gynecol (1987) 2.00
Evidence for a common binding cavity for three general anesthetics within the GABAA receptor. J Neurosci (2001) 2.00
Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc Natl Acad Sci U S A (2001) 1.99
Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol Cell Biol (1998) 1.99
Exercise Evaluation Randomised Trial (EXERT): a randomised trial comparing GP referral for leisure centre-based exercise, community-based walking and advice only. Health Technol Assess (2007) 1.98
Use of checkerboard DNA-DNA hybridization to study complex microbial ecosystems. Oral Microbiol Immunol (2004) 1.96
Interleukin 4 (B-cell stimulatory factor 1) can enhance or antagonize the factor-dependent growth of hemopoietic progenitor cells. Proc Natl Acad Sci U S A (1987) 1.96
Parenchymal transection of the kidney inflicted by endocatch bag entrapment during a laparoscopic donor nephrectomy. Am J Transplant (2006) 1.95
Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis. J Clin Invest (1998) 1.93
Predictors of large esophageal varices in patients with cirrhosis. Am J Gastroenterol (1999) 1.93
Novel method for killing poultry in houses with dry foam created using nitrogen. Vet Rec (2008) 1.92
Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody. J Virol (1993) 1.90
Insulin aspart (B28 asp-insulin): a fast-acting analog of human insulin: absorption kinetics and action profile compared with regular human insulin in healthy nondiabetic subjects. Diabetes Care (1999) 1.90
Gastrointestinal Kaposi's sarcoma in patients with acquired immunodeficiency syndrome. Endoscopic and autopsy findings. Gastroenterology (1985) 1.90
Otitis externa in UK general practice: a survey using the UK General Practice Research Database. Br J Gen Pract (2001) 1.89