Published in Genes Dev on February 15, 2001
Central roles of small GTPases in the development of cell polarity in yeast and beyond. Microbiol Mol Biol Rev (2007) 3.30
Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass. Curr Opin Cell Biol (2002) 2.68
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow. J Cell Biol (2003) 2.40
A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization. EMBO J (2002) 2.39
Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. J Cell Biol (2004) 2.27
Hyphal elongation is regulated independently of cell cycle in Candida albicans. Mol Biol Cell (2002) 1.51
A role for cell polarity proteins in mitotic exit. EMBO J (2002) 1.51
A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast. J Cell Biol (2001) 1.44
The nucleotide exchange factor Cdc24p may be regulated by auto-inhibition. EMBO J (2004) 1.44
Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules. Mol Cell Biol (2002) 1.36
Regulation of endocytic traffic by Rho GTPases. Biochem J (2003) 1.31
Hyphal tip-associated localization of Cdc42 is F-actin dependent in Candida albicans. Eukaryot Cell (2002) 1.27
Cadherin-mediated intercellular adhesion and signaling cascades involving small GTPases. Cold Spring Harb Perspect Biol (2009) 1.17
Interaction between a Ras and a Rho GTPase couples selection of a growth site to the development of cell polarity in yeast. Mol Biol Cell (2003) 1.16
Gef1p, a new guanine nucleotide exchange factor for Cdc42p, regulates polarity in Schizosaccharomyces pombe. Mol Biol Cell (2003) 1.07
Site-specific regulation of the GEF Cdc24p by the scaffold protein Far1p during yeast mating. EMBO J (2004) 1.00
The RHO1-specific GTPase-activating protein LRG1 regulates polar tip growth in parallel to Ndr kinase signaling in Neurospora. Mol Biol Cell (2008) 0.97
Rgf1p is a specific Rho1-GEF that coordinates cell polarization with cell wall biogenesis in fission yeast. Mol Biol Cell (2006) 0.96
Activation of Rac1 by the guanine nucleotide exchange factor Dck1 is required for invasive filamentous growth in the pathogen Candida albicans. Mol Biol Cell (2008) 0.94
Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion. Cell Adh Migr (2011) 0.92
Functional analysis of the Caenorhabditis elegans UNC-73B PH domain demonstrates a role in activation of the Rac GTPase in vitro and axon guidance in vivo. Mol Cell Biol (2003) 0.91
Maintenance of mating cell integrity requires the adhesin Fig2p. Eukaryot Cell (2002) 0.90
Functional connection between the Clb5 cyclin, the protein kinase C pathway and the Swi4 transcription factor in Saccharomyces cerevisiae. Genetics (2005) 0.89
Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase. Mol Biol Cell (2008) 0.88
Separate membrane targeting and anchoring domains function in the localization of the S. cerevisiae Cdc24p guanine nucleotide exchange factor. Curr Genet (2004) 0.87
Cla4 kinase triggers destruction of the Rac1-GEF Cdc24 during polarized growth in Ustilago maydis. Mol Biol Cell (2011) 0.86
Rac activation: P-Rex1 - a convergence point for PIP(3) and Gbetagamma? Curr Biol (2002) 0.86
Cdc42p is activated during vacuole membrane fusion in a sterol-dependent subreaction of priming. J Biol Chem (2009) 0.84
Mechanisms of CDC-42 activation during contact-induced cell polarization. J Cell Sci (2013) 0.84
Cdc42p-interacting protein Bem4p regulates the filamentous-growth mitogen-activated protein kinase pathway. Mol Cell Biol (2014) 0.76
Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway. Mol Biol Cell (2014) 0.76
A big new job for small GTPases. Small GTPases (2012) 0.76
The checkpoint-dependent nuclear accumulation of Rho1p exchange factor Rgf1p is important for tolerance to chronic replication stress. Mol Biol Cell (2014) 0.75
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature (1992) 7.68
The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis. Nature (2008) 5.42
Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science (1997) 5.27
Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism. Proc Natl Acad Sci U S A (1999) 3.17
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. Cell (2001) 3.16
Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast. J Cell Biol (1999) 3.03
Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J (1993) 2.91
Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev (1997) 2.77
Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast. Mol Cell (2000) 2.52
Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints. Genes Chromosomes Cancer (1992) 2.31
The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science (1998) 2.29
Adverse effect of noise in the operating theatre on surgical-site infection. Br J Surg (2011) 2.15
Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev (1997) 2.12
Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast. Mol Cell Biol (2001) 1.87
FAR1 is required for oriented polarization of yeast cells in response to mating pheromones. J Cell Biol (1995) 1.87
Sequence and identification of the nucleotide binding site for the elongation factor Tu from Thermus thermophilus HB8. Nucleic Acids Res (1987) 1.85
Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mating. Nat Cell Biol (2000) 1.78
Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo. Curr Biol (2000) 1.68
MAP kinase dynamics in response to pheromones in budding yeast. Nat Cell Biol (2001) 1.63
Thigh emphysema and hip pain secondary to gastrointestinal perforation. Surgery (1975) 1.60
Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia? J Clin Invest (1992) 1.58
Continuous left hemidiaphragm sign revisited: a case of spontaneous pneumopericardium and literature review. Heart (2002) 1.56
Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev (1999) 1.56
Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4. EMBO J (2000) 1.54
The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex. EMBO J (1998) 1.50
Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2. J Cell Biol (1993) 1.49
Expression of chicken lamin B2 in Escherichia coli: characterization of its structure, assembly, and molecular interactions. J Cell Biol (1991) 1.47
Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma: one probably imprinted, another associated with N-myc amplification. Hum Mol Genet (1995) 1.45
Ischaemia/reperfusion contributes to colonic injury following experimental aortic surgery. Eur J Vasc Endovasc Surg (2001) 1.41
Immunological characterization of avian MAP kinases: evidence for nuclear localization. Mol Biol Cell (1992) 1.40
Actin cytoskeleton organization regulated by the PAK family of protein kinases. Curr Biol (1998) 1.35
Total revascularization with T grafts. Ann Thorac Surg (1994) 1.34
Gic2p may link activated Cdc42p to components involved in actin polarization, including Bni1p and Bud6p (Aip3p). Mol Cell Biol (2000) 1.33
Newborn screening for congenital adrenal hyperplasia: additional steroid profile using liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab (2007) 1.30
Association of phosphatidylinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activation. J Biol Chem (1994) 1.27
The role of the head and tail domain in lamin structure and assembly: analysis of bacterially expressed chicken lamin A and truncated B2 lamins. J Struct Biol (1992) 1.25
Are nitrite and N-nitroso compounds in gastric juice risk factors for carcinoma in the operated stomach? Lancet (1980) 1.21
Detection of chromosome imbalances in retinoblastoma by parallel karyotype and CGH analyses. Genes Chromosomes Cancer (2000) 1.21
Two distinct deleted regions on the short arm of chromosome 1 in neuroblastoma. Genes Chromosomes Cancer (1994) 1.18
Genomic structure of the EWS gene and its relationship to EWSR1, a site of tumor-associated chromosome translocation. Genomics (1993) 1.18
The mycorrhiza helper Pseudomonas fluorescens BBc6R8 has a specific priming effect on the growth, morphology and gene expression of the ectomycorrhizal fungus Laccaria bicolor S238N. New Phytol (2007) 1.17
Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation. Hum Mol Genet (1995) 1.17
Genetic variability and integration of Merkel cell polyomavirus in Merkel cell carcinoma. Virology (2012) 1.16
Cyclin B/cdc2 induces c-Mos stability by direct phosphorylation in Xenopus oocytes. Mol Biol Cell (2001) 1.14
Evidence of a selective major vascular marginal pool of lymphocytes in the lung. Am Rev Respir Dis (1987) 1.09
Functional analysis of FAR1 in yeast. Methods Enzymol (1997) 1.03
Malignant melanoma of the soft parts (clear-cell sarcoma): confirmation of EWS and ATF-1 gene fusion caused by a t(12;22) translocation. Mod Pathol (1997) 1.02
Programming of cell polarity in budding yeast by endogenous and exogenous signals. Cold Spring Harb Symp Quant Biol (1995) 1.01
Influence of different pressure gradients on late clinical outcome after aortic valve replacement. J Heart Valve Dis (1992) 0.98
Assessment of chromosome 22 anomalies in neurinomas by combined karyotype and RFLP analyses. Cancer Genet Cytogenet (1990) 0.97
Technical advances in ultrasound and MR imaging of carpal tunnel syndrome. Eur Radiol (2000) 0.97
p34cdc2 acts as a lamin kinase in fission yeast. J Cell Biol (1991) 0.96
MAP kinase dynamics in yeast. Biol Cell (2001) 0.93
Presence of tumor cells in bone marrow but not in blood is associated with adverse prognosis in patients with Ewing's tumor. Société Française d'Oncologie Pédiatrique. J Clin Oncol (1998) 0.92
Evidence for genetic heterogeneity of pseudohypoaldosteronism type 1: identification of a novel mutation in the human mineralocorticoid receptor in one sporadic case and no mutations in two autosomal dominant kindreds. J Clin Endocrinol Metab (2001) 0.92
CGH analysis of secondary genetic changes in Ewing tumors: correlation with metastatic disease in a series of 43 cases. Cancer Genet Cytogenet (2001) 0.91
Vertebrate cdc2 kinase: its regulation by phosphorylation and its mitotic targets. Cold Spring Harb Symp Quant Biol (1991) 0.91
CYP11B1 mutations causing congenital adrenal hyperplasia due to 11 beta-hydroxylase deficiency. J Clin Endocrinol Metab (1996) 0.90
Nitrite and nitrosamines in gastric juice: risk factors for gastric cancer? Scand J Gastroenterol (1982) 0.90
Fluorescent pseudo-peptide linear vasopressin antagonists: design, synthesis, and applications. J Med Chem (1999) 0.90
New insight into the molecular basis of 3beta-hydroxysteroid dehydrogenase deficiency: identification of eight mutations in the HSD3B2 gene eleven patients from seven new families and comparison of the functional properties of twenty-five mutant enzymes. J Clin Endocrinol Metab (1999) 0.89
Gonadal histology with testicular carcinoma in situ in a 15-year-old 46,XY female patient with a premature termination in the steroidogenic acute regulatory protein causing congenital lipoid adrenal hyperplasia. J Clin Endocrinol Metab (1999) 0.89
Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics (2000) 0.88
c-Mos and cyclin B/cdc2 connections during Xenopus oocyte maturation. Biol Cell (2001) 0.88
Blood conservation during myocardial revascularization. Ann Thorac Surg (1979) 0.87
[Causes and course of fornix rupture]. Aktuelle Urol (2010) 0.87
[Oral pancreas function test with FDL in the diagnosis of chronic pancreatitis]. Klin Wochenschr (1983) 0.86
Mapping of Ras-related GTP-binding proteins by GTP overlay following two-dimensional gel electrophoresis. Proc Natl Acad Sci U S A (1994) 0.86
Amino acid substitution R384P in aldosterone synthase causes corticosterone methyloxidase type I deficiency. J Clin Endocrinol Metab (1995) 0.85
Mapping of human chromosome 22 with a panel of somatic cell hybrids. Genomics (1991) 0.85
Significant improvement in flow through a potential internal mammary graft after partial approximation of the sternum. J Thorac Cardiovasc Surg (1984) 0.85
Clinical relevance of loss heterozygosity of the short arm of chromosome 1 in neuroblastoma: a single-institution study. Int J Cancer (1996) 0.84
Late survival following use of intraaortic balloon pump in revascularization operations. Ann Thorac Surg (1980) 0.84
N-MYC amplification, loss of heterozygosity on the short arm of chromosome 1 and DNA ploidy in retinoblastoma. Eur J Cancer (1996) 0.83
Incidence and prognostic value of tumour cells detected by RT-PCR in peripheral blood stem cell collections from patients with Ewing tumour. Br J Cancer (2006) 0.83
Adsorption energetics of CO on supported Pd nanoparticles as a function of particle size by single crystal microcalorimetry. Phys Chem Chem Phys (2011) 0.83
Cytogenetic and molecular analysis of a t(1;22)(p36;q11.2) in a rhabdoid tumor with a putative homozygous deletion of chromosome 22. Genes Chromosomes Cancer (1998) 0.82
Prospective evaluation of Nmyc amplification and deletion of the short arm of chromosome 1 in neuroblastoma tumours: a single institution study. Prog Clin Biol Res (1994) 0.81
Features of Antley-Bixler syndrome in an infant born to a mother with pregnancy luteoma. Eur J Pediatr (2000) 0.81
A higher rate of hyperandrogenic disorders in female-to-male transsexuals. Psychoneuroendocrinology (1997) 0.80
[Acrodermatitis enteropathica. Case in a 2-year-old child presenting beta-2 A-globulin deficiency]. Pediatrie (1966) 0.80
Drought and air warming affects abundance and exoenzyme profiles of Cenococcum geophilum associated with Quercus robur, Q. petraea and Q. pubescens. Plant Biol (Stuttg) (2012) 0.79
Part of Xenopus translin is localized in the centrosomes during mitosis. Biochem Biophys Res Commun (2000) 0.79
A new insight into the molecular basis of 3beta-hydroxysteroid dehydrogenase deficiency. Endocr Res (2000) 0.79
Rapid quantification of conjugated and unconjugated bile acids and C27 precursors in dried blood spots and small volumes of serum. J Lipid Res (2010) 0.79
Neighborhood effects in visual word recognition: effects of letter delay and nonword context difficulty. J Exp Psychol Learn Mem Cogn (1994) 0.79
X-linked congenital adrenal hypoplasia: new mutations and long-term follow-up in three patients. Clin Endocrinol (Oxf) (2000) 0.79
Relevance of major histocompatibility complex class II expression as a hallmark for the cellular differentiation in the human adrenal cortex. J Clin Endocrinol Metab (1997) 0.78
Follow up of growth and steroids in premature adrenarche. Eur J Pediatr (1995) 0.78
Footedness of left- and right-handers. Am J Psychol (1979) 0.78
Functional profiling and distribution of the forest soil bacterial communities along the soil mycorrhizosphere continuum. Microb Ecol (2013) 0.78
A multiplex PCR assay for routine evaluation of deletion of the short arm of chromosome 1 in neuroblastoma. Eur J Cancer (1995) 0.77
Variability of pulsatile luteinizing hormone secretion in young male volunteers. Eur J Endocrinol (1994) 0.77
Impairment of 11 beta-hydroxylase but not 21-hydroxylase in adrenal 'incidentalomas'. Eur J Endocrinol (1997) 0.77
Growth hormone and parathyroid hormone stimulate IGFBP-3 in rat osteoblasts. Am J Physiol (1994) 0.77
Initial clinical experience with a new temporary left ventricular assist device. Ann Thorac Surg (1980) 0.77
Production of IGFBP-3 by connective tissue and endothelial cells. Growth Regul (1993) 0.76
Mitotic exit: closing the gap. Mol Cell (2001) 0.76