Published in Hypertension on February 01, 2001
Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metab (2010) 3.05
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. Am J Physiol Renal Physiol (2008) 1.44
hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists. J Am Soc Nephrol (2005) 1.31
Therapeutic potential of resveratrol in Alzheimer's disease. BMC Neurosci (2008) 1.19
Activation of peroxisome proliferator-activated receptor delta inhibits streptozotocin-induced diabetic nephropathy through anti-inflammatory mechanisms in mice. Diabetes (2011) 1.07
Therapeutic approach to FSGS in children. Pediatr Nephrol (2006) 1.01
Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts. Br J Pharmacol (2008) 0.95
Peroxisome proliferator-activated receptors in diabetic nephropathy. PPAR Res (2009) 0.81
MicroRNA-27a Induces Mesangial Cell Injury by Targeting of PPARγ, and its In Vivo Knockdown Prevents Progression of Diabetic Nephropathy. Sci Rep (2016) 0.81
PPARγ and chronic kidney disease. Pediatr Nephrol (2010) 0.80
The role of nuclear receptors in the kidney in obesity and metabolic syndrome. Genes Nutr (2012) 0.77
Peroxisome proliferator-activated receptor γ Pro12Ala polymorphism decrease the risk of diabetic nephropathy in type 2 diabetes: a meta analysis. Int J Clin Exp Med (2015) 0.75
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. J Biol Chem (1994) 4.90
An efficient procedure for genotyping single nucleotide polymorphisms. Nucleic Acids Res (2001) 4.77
Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (1998) 3.41
Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther (2004) 2.97
Monoclonal antibodies to murine hepatitis virus-4 (strain JHM) define the viral glycoprotein responsible for attachment and cell--cell fusion. Virology (1982) 2.94
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2001) 2.85
CRMP-2 induces axons in cultured hippocampal neurons. Nat Neurosci (2001) 2.70
Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility. J Cell Biol (1999) 2.17
Heterozygous deletion of ITPR1, but not SUMF1, in spinocerebellar ataxia type 16. J Med Genet (2007) 2.06
Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway. J Cell Biol (2001) 1.85
Hepatocellular carcinoma presenting as intrabile duct tumor growth: a clinicopathologic study of 24 cases. Cancer (1982) 1.80
Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia. J Clin Invest (1996) 1.78
Expression and function of PPARgamma in rat and human vascular smooth muscle cells. Circulation (2000) 1.73
Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arterioscler Thromb Vasc Biol (1999) 1.72
Effect of a phytoestrogen food supplement on reproductive health in normal males. Clin Sci (Lond) (2001) 1.72
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes (1997) 1.70
Splenic artery embolization before laparoscopic splenectomy in children. Surg Endosc (2005) 1.65
Acute myelitis associated with hyperIgEemia and atopic dermatitis. J Neurol Sci (1997) 1.62
Angiotensin II has multiple profibrotic effects in human cardiac fibroblasts. Circulation (2000) 1.58
Hyperprolactinemia in optico-spinal multiple sclerosis. Intern Med (2000) 1.58
Evaluation of angiogenesis in non-small cell lung cancer: comparison between anti-CD34 antibody and anti-CD105 antibody. Clin Cancer Res (2001) 1.55
Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts. Oncogene (1999) 1.55
Retinoids inhibit proliferation of human coronary smooth muscle cells by modulating cell cycle regulators. Arterioscler Thromb Vasc Biol (2001) 1.54
Two novel 1alpha-hydroxylase mutations in French-Canadians with vitamin D dependency rickets type I1. Kidney Int (1998) 1.51
T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy. Kidney Int (2008) 1.48
CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration. Oncogene (1999) 1.48
Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes. Cancer Res (1996) 1.46
Transduction of retrovirus-mediated NeoR gene into CD34+ cells purified from granulocyte colony-stimulating factor (G-CSF)-mobilized infant and cord blood. Exp Hematol (1997) 1.43
Western versus Asian types of multiple sclerosis: immunogenetically and clinically distinct disorders. Ann Neurol (1996) 1.42
Quantitative estimation of dietary intake in patients on hemodialysis. Int J Artif Organs (1988) 1.41
The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme. J Cell Biol (1998) 1.39
Mutation of the N-terminal proline 9 of BLMA from Streptomyces verticillus abolishes the binding affinity for bleomycin. FEBS Lett (1999) 1.39
Risk of cytomegalovirus infection after peripheral blood stem cell transplantation. Bone Marrow Transplant (1997) 1.38
Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter. Proc Natl Acad Sci U S A (1998) 1.38
Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization. Invest Ophthalmol Vis Sci (2000) 1.37
Peroxisome proliferator-activated receptor gamma ligands inhibit retinoblastoma phosphorylation and G1--> S transition in vascular smooth muscle cells. J Biol Chem (2000) 1.36
Angiotensin II induces migration and Pyk2/paxillin phosphorylation of human monocytes. Hypertension (2001) 1.32
Inhibition of myosin phosphatase by upregulated rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta. Circulation (2000) 1.30
Blood pressure lowering by pioglitazone. Evidence for a direct vascular effect. J Clin Invest (1995) 1.29
Osteopontin is produced by rat cardiac fibroblasts and mediates A(II)-induced DNA synthesis and collagen gel contraction. J Clin Invest (1996) 1.27
Muscle fiber type specificity in insulin signal transduction. Am J Physiol (1999) 1.25
Primary human immunodeficiency virus type 1 viremia and central nervous system invasion in a novel hu-PBL-immunodeficient mouse strain. J Virol (1997) 1.23
Antioxidant efficacy of phytoestrogens in chemical and biological model systems. Arch Biochem Biophys (1998) 1.22
Endoscopic treatment of a long fibroepithelial ureteral polyp. Int J Urol (2001) 1.21
Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA. Proc Natl Acad Sci U S A (1997) 1.20
Blunted parasympathetic modulation in salt-sensitive patients with essential hypertension: evaluation by power-spectral analysis of heart-rate variability. J Hypertens (1997) 1.18
Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators. Biochem Biophys Res Commun (2001) 1.17
PDK1 inhibition is a novel therapeutic target in multiple myeloma. Br J Cancer (2012) 1.16
Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells. Int J Radiat Biol (1992) 1.16
Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1 alpha-hydroxylase. Biochem Biophys Res Commun (1997) 1.16
PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells. J Cardiovasc Pharmacol (1999) 1.15
Myocardial osteopontin expression is associated with left ventricular hypertrophy. Circulation (1997) 1.15
TNFalpha induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2. Atherosclerosis (2001) 1.14
Mitogen-activated protein kinase activation is involved in platelet-derived growth factor-directed migration by vascular smooth muscle cells. Hypertension (1997) 1.14
Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats. Diabetes (1997) 1.13
Comparative analysis of engraftment after cryopreservation of peripheral blood stem cell autografts by controlled- versus uncontrolled-rate methods. Bone Marrow Transplant (1994) 1.13
Endogenous interleukin-8 (IL-8) surge in granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization. Blood (1999) 1.12
Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes. Eur J Pharmacol (2000) 1.12
HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies. Brain (1999) 1.12
Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans. Mutat Res (2001) 1.11
Maternal sex chromosome non-disjunction: evidence for X chromosome-specific risk factors. Hum Mol Genet (2001) 1.11
Prohibitin, a protein downregulated by androgens, represses androgen receptor activity. Oncogene (2006) 1.11
Distribution of albumin- and/or alpha-fetoprotein-positive cells in hepatocellular carcinoma. Lab Invest (1981) 1.10
Characterization of an in vitro persistent-state measles virus infection: establishment and virological characterization of the BGM/MV cell line. Infect Immun (1975) 1.09
Seasonal variations in office, home and 24 h ambulatory blood pressure in patients with essential hypertension. J Hypertens (1996) 1.09
Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins. J Biol Chem (1999) 1.09
Office blood pressure variability as a predictor of acute myocardial infarction in elderly patients receiving antihypertensive therapy. J Hum Hypertens (2002) 1.09
Single cell gel electrophoresis: detection of DNA damage at different levels of sensitivity. Electrophoresis (1999) 1.08
Response of experimental retinal neovascularization to thiazolidinediones. Arch Ophthalmol (2001) 1.06
The inhibition of repair in UV irradiated human cells. Mutat Res (1977) 1.05
Nutritional supplementation with antioxidants decreases chromosomal damage in humans. Mutagenesis (2003) 1.05
Vitamins C and E: acute interactive effects on biomarkers of antioxidant defence and oxidative stress. Mutat Res (2004) 1.05
Synergistic defense system by cooperative natural effectors against metastasis of B16 melanoma cells in H-2-associated control: different behavior of H-2+ and H-2- cells in metastatic processes. J Immunol (1986) 1.05
TNF-alpha-induced migration of vascular smooth muscle cells is MAPK dependent. Hypertension (1999) 1.04
Association of the HLA-DPB1*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders. Tissue Antigens (2009) 1.04
Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non-small cell lung cancer. Cancer Res (2000) 1.03
Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases. Carcinogenesis (1985) 1.02
In vivo interaction of AF-6 with activated Ras and ZO-1. Biochem Biophys Res Commun (1999) 1.02
Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases. Int J Hematol (1998) 1.02
Office blood pressure variability as a predictor of brain infarction in elderly hypertensive patients. Hypertens Res (2000) 1.01
Quercetin and myricetin protect against hydrogen peroxide-induced DNA damage (strand breaks and oxidised pyrimidines) in human lymphocytes. Mutat Res (1997) 1.00
Coincident linkage of fasting plasma insulin and blood pressure to chromosome 7q in hypertensive hispanic families. Circulation (2001) 1.00
Bioavailability and efficiency of rutin as an antioxidant: a human supplementation study. Eur J Clin Nutr (2000) 1.00
Insulin and angiotensin II are additive in stimulating TGF-beta 1 and matrix mRNAs in mesangial cells. Kidney Int (1996) 1.00
Angiotensin II, adhesion, and cardiac fibrosis. Cardiovasc Res (2000) 1.00
Initial rates of DNA incision in UV-irradiated human cells: differences between normal, xeroderma pigmentosum and tumour cells. Mutat Res (1982) 1.00
Evidence for joint genetic control of insulin sensitivity and systolic blood pressure in hispanic families with a hypertensive proband. Circulation (2001) 0.99
Inhibitors of repair DNA synthesis. Nucleic Acids Res (1982) 0.99
Serum levels of soluble intercellular adhesion molecule-1 (ICAM-1) and the expression of ICAM-1 mRNA in uterine cervical cancer. Gynecol Oncol (1997) 0.99
Long-term, high dose interferon-alpha treatment in HTLV-I-associated myelopathy/tropical spastic paraparesis: a combined clinical, virological and immunological study. J Neurol Sci (1997) 0.99
Postexercise glucose uptake and glycogen synthesis in skeletal muscle from GLUT4-deficient mice. FASEB J (1999) 0.99