Published in Biochim Biophys Acta on March 21, 2001
Development of mice expressing a single D-type cyclin. Genes Dev (2002) 2.43
Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation. Proc Natl Acad Sci U S A (2003) 1.68
GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium. Mol Cell Biol (2008) 1.56
Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding. J Biol Chem (2010) 1.54
Deciphering the retinoblastoma protein phosphorylation code. Trends Biochem Sci (2012) 1.46
Components of an interdependent unit within the SSU processome regulate and mediate its activity. Mol Cell Biol (2002) 1.45
Salivary duct carcinoma: immunohistochemical profile of an aggressive salivary gland tumour. J Clin Pathol (2003) 1.21
An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein. Nat Struct Mol Biol (2010) 1.20
Retinoic acid regulates cell cycle progression and cell differentiation in human monocytic THP-1 cells. Exp Cell Res (2004) 1.07
Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest. Mol Cell Biol (2006) 1.05
Selectivity and potency of cyclin-dependent kinase inhibitors. AAPS J (2006) 1.04
Regulation of the retinoblastoma proteins by the human herpesviruses. Cell Div (2009) 1.02
Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells. Mol Cell Biol (2011) 0.97
Cell cycle activation and spinal cord injury. Neurotherapeutics (2011) 0.97
RB activation defect in tumor cell lines. Proc Natl Acad Sci U S A (2002) 0.96
Tale of a tegument transactivator: the past, present and future of human CMV pp71. Future Virol (2012) 0.94
Cyclin D does not provide essential Cdk4-independent functions in Drosophila. Genetics (2004) 0.92
CCAAT/enhancer-binding protein beta inhibits proliferation in monocytic cells by affecting the retinoblastoma protein/E2F/cyclin E pathway but is not directly required for macrophage morphology. J Biol Chem (2011) 0.91
Tumor suppressors and cell-cycle proteins in lung cancer. Patholog Res Int (2011) 0.89
Minichromosome maintenance (Mcm) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia. Br J Cancer (2003) 0.89
Protection against Cancer with Medicinal Herbs via Activation of Tumor Suppressor. J Oncol (2012) 0.85
A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations. Antimicrob Agents Chemother (2015) 0.84
Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies. Invest New Drugs (2011) 0.82
The B-domain lysine patch of pRB is required for binding to large T antigen and release of E2F by phosphorylation. Mol Cell Biol (2002) 0.82
Mitogenic Signaling by the gep Oncogene Involves the Upregulation of S-Phase Kinase-Associated Protein 2. Genes Cancer (2010) 0.82
17Alpha-estradiol arrests cell cycle progression at G2/M and induces apoptotic cell death in human acute leukemia Jurkat T cells. Toxicol Appl Pharmacol (2008) 0.81
Tumors with nonfunctional retinoblastoma protein are killed by reduced γ-tubulin levels. J Biol Chem (2012) 0.80
Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget. Oncotarget (2015) 0.80
Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of central nervous system diseases. Neurobiol Dis (2009) 0.80
Integrated stability and activity control of the Drosophila Rbf1 retinoblastoma protein. J Biol Chem (2014) 0.79
Interaction of fish aryl hydrocarbon receptor paralogs (AHR1 and AHR2) with the retinoblastoma protein. Aquat Toxicol (2009) 0.78
Very low oxygen concentration (0.1%) reveals two FDCP-Mix cell subpopulations that differ by their cell cycling, differentiation and p27KIP1 expression. Cell Death Differ (2010) 0.78
Molecular Determinants for the Inactivation of the Retinoblastoma Tumor Suppressor by the Viral Cyclin-dependent Kinase UL97. J Biol Chem (2015) 0.78
Matrine inhibits vascular smooth muscle cell proliferation by modulating the expression of cell cycle regulatory genes. Acta Pharmacol Sin (2010) 0.78
Epstein-Barr virus infection correlates with the expression of COX-2, p16(INK4A) and p53 in classic Hodgkin lymphoma. Int J Clin Exp Pathol (2013) 0.77
Phospho-T356RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck. Oncotarget (2015) 0.76
NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio (2015) 0.75
FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21(Cip1) CDK inhibitor. Oncogene (2016) 0.75
Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model. Front Cell Neurosci (2015) 0.75
Epstein-Barr virus infection is inversely correlated with the expression of retinoblastoma protein in Reed-Sternberg cells in classic Hodgkin lymphoma. Int J Clin Exp Pathol (2014) 0.75
Human cytomegalovirus-encoded viral cyclin-dependent kinase (v-CDK) UL97 phosphorylates and inactivates the retinoblastoma protein-related p107 and p130 proteins. J Biol Chem (2017) 0.75
Investigation of cyclin D1 rs9344 G>A polymorphism in colorectal cancer: a meta-analysis involving 13,642 subjects. Onco Targets Ther (2016) 0.75
Immunohistochemical investigation of F344/N rat islet cell tumors from national toxicology program studies. Toxicol Pathol (2012) 0.75
Fluvastatin inhibits AGE-induced cell proliferation and migration via an ERK5-dependent Nrf2 pathway in vascular smooth muscle cells. PLoS One (2017) 0.75
TGF-β-target genes are differentially regulated in corneal epithelial cells and fibroblasts. New Front Ophthalmol (2017) 0.75