PubRank

M T Diaz-Meco

Author PubWeight™ 58.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway. EMBO J 2000 3.83
2 The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation. J Cell Biol 2000 3.34
3 Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway. Mol Cell 2001 3.05
4 The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation. EMBO J 1999 2.80
5 Protein kinase C zeta isoform is critical for mitogenic signal transduction. Cell 1993 2.54
6 Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62. Mol Cell Biol 1998 2.35
7 Activation of IkappaB kinase beta by protein kinase C isoforms. Mol Cell Biol 1999 2.35
8 Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase. J Biol Chem 1994 2.20
9 The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters. EMBO Rep 2000 1.80
10 Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase. Mol Cell Biol 1997 1.76
11 Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis. Cell 1990 1.64
12 Evidence for a role of protein kinase C zeta subspecies in maturation of Xenopus laevis oocytes. Mol Cell Biol 1992 1.63
13 Inhibition of protein kinase C zeta subspecies blocks the activation of an NF-kappa B-like activity in Xenopus laevis oocytes. Mol Cell Biol 1993 1.60
14 The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor. J Biol Chem 2001 1.49
15 The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression. EMBO J 1999 1.48
16 The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway. J Biol Chem 1998 1.46
17 Phosphatidylcholine hydrolysis activates NF-kappa B and increases human immunodeficiency virus replication in human monocytes and T lymphocytes. J Virol 1993 1.44
18 Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction. Mol Cell Biol 1993 1.40
19 PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways. Cell Death Differ 2006 1.40
20 Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex. Cell Death Differ 2009 1.35
21 Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C. J Biol Chem 1995 1.29
22 Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes. J Virol 1996 1.29
23 Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade. Mol Cell Biol 1997 1.26
24 Kinetic evidence of a rapid activation of phosphatidylcholine hydrolysis by Ki-ras oncogene. Possible involvement in late steps of the mitogenic cascade. J Biol Chem 1990 1.20
25 Evidence for a role of phosphatidylcholine-hydrolysing phospholipase C in the regulation of protein kinase C by ras and src oncogenes. EMBO J 1990 1.16
26 Identification of heterogeneous ribonucleoprotein A1 as a novel substrate for protein kinase C zeta. J Biol Chem 1995 1.15
27 Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction. Mol Cell Biol 1992 1.11
28 Requirement of phospholipase C-catalyzed hydrolysis of phosphatidylcholine for maturation of Xenopus laevis oocytes in response to insulin and ras p21. J Biol Chem 1991 1.09
29 Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway. Mol Cell Biol 2001 1.04
30 Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C. EMBO J 1991 1.00
31 NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype. Mol Cell Biol 1994 0.99
32 Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzed hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C. J Biol Chem 1991 0.94
33 Cleavage of zetaPKC but not lambda/iotaPKC by caspase-3 during UV-induced apoptosis. J Biol Chem 1999 0.93
34 Cross-talk between different enhancer elements during mitogenic induction of the human stromelysin-1 gene. J Biol Chem 1996 0.90
35 Zeta PKC plays a critical role during stromelysin promoter activation by platelet-derived growth factor through a novel palindromic element. J Biol Chem 1994 0.89
36 Molecular characterization of a novel transcription factor that controls stromelysin expression. Mol Cell Biol 1995 0.87
37 Regulation and role of the atypical PKC isoforms in cell survival during tumor transformation. Adv Enzyme Regul 2001 0.79
38 Activation of phosphatidylcholine-specific phospholipase C in cell growth and oncogene transformation. Biochem Soc Trans 1989 0.78