Published in J Biol Chem on March 26, 2001
Transcriptional regulation by AIRE: molecular mechanisms of central tolerance. Nat Rev Immunol (2008) 1.99
Chromosomal clustering of genes controlled by the aire transcription factor. Proc Natl Acad Sci U S A (2005) 1.49
The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation. Nucleic Acids Res (2009) 1.46
The Finnish Disease Heritage III: the individual diseases. Hum Genet (2003) 1.36
AIRE functions as an E3 ubiquitin ligase. J Exp Med (2004) 1.19
DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity. Biochim Biophys Acta (2007) 1.10
Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis. Immunogenetics (2008) 0.99
Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a model disease to study molecular aspects of endocrine autoimmunity. Clin Exp Immunol (2004) 0.97
Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+ CD25+ regulatory T cells. Blood (2005) 0.96
Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nat Genet (2015) 0.95
Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription. Nucleic Acids Res (2011) 0.88
Expression of thyrotropin receptor, thyroglobulin, sodium-iodide symporter, and thyroperoxidase by fibrocytes depends on AIRE. J Clin Endocrinol Metab (2014) 0.84
Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue. Clin Exp Immunol (2011) 0.82
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1. J Clin Endocrinol Metab (2016) 0.80
AIRE acetylation and deacetylation: effect on protein stability and transactivation activity. J Biomed Sci (2014) 0.79
A functional alternative splicing mutation in AIRE gene causes autoimmune polyendocrine syndrome type 1. PLoS One (2013) 0.79
SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis. J Immunol Res (2015) 0.77
Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells. J Biol Chem (2016) 0.76
In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes. Biol Open (2014) 0.75
Altered Immune Activation and IL-23 Signaling in Response to Candida albicans in Autoimmune Polyendocrine Syndrome Type 1. Front Immunol (2017) 0.75
Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation (2001) 5.87
Positional cloning of the APECED gene. Nat Genet (1997) 5.47
Long latency precedes overt seroconversion in sexually transmitted human-immunodeficiency-virus infection. Lancet (1987) 3.68
In vitro cellular tropism of human B-lymphotropic virus (human herpesvirus-6). J Exp Med (1988) 2.81
Opsonic requirements for staphylococcal phagocytosis. Heterogeneity among strains. Immunology (1977) 2.73
In vitro activity of cephalosporins against methicillin-resistant, coagulase-negative staphylococci. J Infect Dis (1978) 2.39
Denitrification Studies with 13N-Labeled Nitrate. Science (1976) 1.97
Putative receptor binding sites on alphaviruses as visualized by cryoelectron microscopy. Proc Natl Acad Sci U S A (1995) 1.81
Experience of the Polycythemia Vera Study Group with essential thrombocythemia: a final report on diagnostic criteria, survival, and leukemic transition by treatment. Semin Hematol (1997) 1.78
Plaque color method for rapid isolation of novel recA mutants of Escherichia coli K-12: new classes of protease-constitutive recA mutants. J Bacteriol (1985) 1.74
Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia (2000) 1.74
Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17 alpha-hydroxylase. Lancet (1992) 1.73
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family. Genomics (2000) 1.70
Humoral immune response to the entire human immunodeficiency virus envelope glycoprotein made in insect cells. Proc Natl Acad Sci U S A (1987) 1.70
Challenge of chimpanzees (Pan troglodytes) immunized with human immunodeficiency virus envelope glycoprotein gp120. J Virol (1989) 1.61
Two subsets of epithelial cells in the thymic medulla. J Exp Med (1992) 1.59
Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia. AIDS (1995) 1.59
Uptake and activity of rifapentine in human peritoneal macrophages and polymorphonuclear leukocytes. Eur J Clin Microbiol (1987) 1.55
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur J Immunol (2000) 1.55
S.H. antigen and chronic liver disease. Lancet (1970) 1.51
NIH conference. Chronic fatigue syndrome research. Definition and medical outcome assessment. Ann Intern Med (1992) 1.50
Vitamin A teratogenicity and risk assessment in the macaque retinoid model. Reprod Toxicol (2000) 1.50
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J Biol Chem (2000) 1.49
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem Biophys Res Commun (1999) 1.48
Detection of thyroid-stimulating hormone receptor and Gsalpha mutations: in 75 toxic thyroid nodules by denaturing gradient gel electrophoresis. J Mol Med (Berl) (2001) 1.45
Correlation of 24-hour urinary protein quantification with spot urine protein:creatinine ratio in lupus nephritis. Lupus (2012) 1.42
Immunoprecipitation of steroidogenic enzyme autoantigens with autoimmune polyglandular syndrome type I (APS I) sera; further evidence for independent humoral immunity to P450c17 and P450c21. Clin Exp Immunol (1997) 1.40
Contact allergy due to colophony. (IX). Sensitization studies with further products isolated after oxidative degradation of resin acids and colophony. Contact Dermatitis (1993) 1.40
Heart transplantation in patients with heparin-induced thrombocytopenia on the Novacor left ventricular assist system. J Heart Lung Transplant (1998) 1.39
Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8. Science (1992) 1.38
Specific cellular immune response and neutralizing antibodies in goats immunized with native or recombinant envelope proteins derived from human T-lymphotropic virus type IIIB and in human immunodeficiency virus-infected men. Proc Natl Acad Sci U S A (1987) 1.37
[Mystery of the blue man: alkaptonuria]. Duodecim (1997) 1.37
Five unique compounds: xyloketals from mangrove fungus Xylaria sp. from the South China Sea coast. J Org Chem (2001) 1.37
A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients. Hum Genet (1998) 1.30
Vesta's shape and morphology. Science (2012) 1.23
Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress. Free Radic Biol Med (2001) 1.21
Autoimmune regulator: from loss of function to autoimmunity. Genes Immun (2003) 1.21
Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins. EMBO J (1983) 1.20
Renal artery stenosis and the nephrotic syndrome. Acta Med Scand (1967) 1.17
Genetic studies in neural tube defects. NTD Collaborative Group. Pediatr Neurosurg (2000) 1.15
Cooperative activation of transcription by autoimmune regulator AIRE and CBP. Biochem Biophys Res Commun (2005) 1.14
Mutation analyses of North American APS-1 patients. Hum Mutat (1999) 1.14
A randomized phase III trial comparing standard and high-dose pemetrexed as second-line treatment in patients with locally advanced or metastatic non-small-cell lung cancer. Ann Oncol (2008) 1.13
Diversity of clinical spectrum of HTLV-III infection. Lancet (1985) 1.12
Hepatic vascular disease and portal hypertension in polycythemia vera and agnogenic myeloid metaplasia: a clinicopathological study of 145 patients examined at autopsy. Hepatology (1990) 1.11
Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins. Mol Endocrinol (1998) 1.11
Teaching peer review. JAMA (1973) 1.10
Pathologist review of the peripheral smear. A mandatory quality assurance activity? Clin Lab Med (1993) 1.10
Validation overview of bio-analytical methods. Gene Ther (2005) 1.09
Studies of radioiodinated fibrinogen. I. Physicochemical properties of the ICl, chloramine-T, and electrolytic reaction products. Biochim Biophys Acta (1972) 1.07
Electron microscopical and immunological observations on the serum-hepatitis (S.H.) antigen in primary biliary cirrhosis. Lancet (1970) 1.07
T-cell response towards HIV in infected individuals with and without zidovudine therapy, and in HIV-exposed sexual partners. AIDS (1989) 1.05
From efficacy to safety: a Polycythemia Vera Study group report on hydroxyurea in patients with polycythemia vera. Semin Hematol (1997) 1.05
Effects of pyocyanine, a phenazine dye from Pseudomonas aeruginosa, on oxidative burst and bacterial killing in human neutrophils. Infect Immun (1989) 1.05
Benign reversible muscle cytochrome c oxidase deficiency: a second case. Neurology (1987) 1.04
Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1). J Pathol (2007) 1.04
Successful amplification of DNA specific for Finnish Borrelia burgdorferi isolates in erythema chronicum migrans but not in circumscribed scleroderma lesions. J Invest Dermatol (1994) 1.04
In vitro demonstration of delayed hypersensitivity to gastric antigens in pernicious anemia. Am J Dig Dis (1972) 1.03
Hemoglobin from a deep-sea hydrothermal-vent copepod. Biol Bull (2000) 1.03
Glial cell line-derived neurotrophic factor requires transforming growth factor-beta for exerting its full neurotrophic potential on peripheral and CNS neurons. J Neurosci (1998) 1.02
Electrn microscopic observations on virus-like particles associated with SH antigen. J Virol (1970) 1.02
Antimicrobial activity of the methanolic extract and of the chemical constituents isolated from Newbouldia laevis. Pharmazie (2007) 1.01
Autoantibodies to cytochrome P450 enzymes P450scc, P450c17, and P450c21 in autoimmune polyglandular disease types I and II and in isolated Addison's disease. J Clin Endocrinol Metab (1994) 1.01
Adalimumab in clinical practice. Outcome in 70 rheumatoid arthritis patients, including comparison of patients with and without previous anti-TNF exposure. Rheumatology (Oxford) (2005) 1.01
The Direct Assessment of Nonvertebral Fractures in Community Experience (DANCE) study: 2-year nonvertebral fragility fracture results. Osteoporos Int (2013) 1.00
Isolation and characterization of human B cell alloantigens. J Immunol (1976) 1.00
Studies of the bone marrow in polycythemia vera and the evolution of myelofibrosis and second hematologic malignancies. Semin Hematol (1986) 1.00
Transverse myelitis and optic neuritis in systemic lupus erythematosus: a case report with magnetic resonance imaging findings. Arthritis Rheum (1987) 1.00
Significance of serum complement levels in chronic liver disease. Gastroenterology (1972) 0.99
Evidence for linkage to psychosis and cerebral asymmetry (relative hand skill) on the X chromosome. Am J Med Genet (1998) 0.99
Interactions of single and combined human immunodeficiency virus type 1 (HIV-1) DNA vaccines. Virology (2001) 0.99
Comparison of binding of [3H]misonidazole and [14C]misonidazole in multicell spheroids. Radiat Res (1985) 0.98
The effects of various load paths and different loads on the load transfer characteristics of the wrist. J Hand Surg Am (1989) 0.98
Nasopharyngeal perforation as a complication of nasogastric intubation. Ear Nose Throat J (1993) 0.98
Bioenergetic heterogeneity of human mitochondrial myopathies: phosphorus magnetic resonance spectroscopy study. Neurology (1987) 0.97
Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a model disease to study molecular aspects of endocrine autoimmunity. Clin Exp Immunol (2004) 0.97
Analysis of extended human leukocyte antigen haplotype association with Addison's disease in three populations. Eur J Endocrinol (2007) 0.96
Hepatotoxicity of salicylates in monolayer cell cultures. Gastroenterology (1978) 0.96
Adult onset Still's disease and collapsing glomerulopathy: successful treatment with intravenous immunoglobulins and mycophenolate mofetil. Rheumatology (Oxford) (2004) 0.96
Immune functions in homosexual men with antibodies to HTLV-III in Finland. Clin Exp Immunol (1985) 0.95
Isolation and initial characterization of the mouse Dnmt3l gene. Cytogenet Cell Genet (2001) 0.95
Intraoperative autologous blood donation preserves red cell mass but does not decrease postoperative bleeding. Ann Thorac Surg (1996) 0.94
SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus. Nucleic Acids Res (2006) 0.94
Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD.8. Hum Immunol (1997) 0.94
Teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: an analysis by gender and menopausal status. Osteoporos Int (2009) 0.94
Medial (hamate) facet of the lunate. J Hand Surg Am (1990) 0.94
Isolate- and group-specific immune responses to the envelope protein of human immunodeficiency virus induced by a live recombinant vaccinia virus in macaques. AIDS Res Hum Retroviruses (1989) 0.93
Benign cervical teratoma in the adult: report of a rare case with dense fibrosis involving adjacent vital structures. Otolaryngol Head Neck Surg (1996) 0.92
Washing of ELISA plates with running tap water. J Immunol Methods (1986) 0.91
Gastrointestinal findings in autoimmune thyroiditis and non-goitrous juvenile hypothyroidism in children. Scand J Gastroenterol (1971) 0.91
Isolation and characterization of the mouse Aire gene. Biochem Biophys Res Commun (1999) 0.91
The effects of inaccurate blood sample volume on prothrombin time (PT) and activated partial thromboplastin time (aPTT). Thromb Haemost (1982) 0.90
The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis. Eur J Clin Pharmacol (1992) 0.90