Published in Cancer Res on March 01, 2001
Requirement of the MRN complex for ATM activation by DNA damage. EMBO J (2003) 6.23
Signal transduction by reactive oxygen species. J Cell Biol (2011) 5.21
ATM and ataxia telangiectasia. EMBO Rep (2004) 2.31
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair. EMBO J (2010) 2.27
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Mitochondrial dysfunction in ataxia-telangiectasia. Blood (2011) 1.93
The ATM protein kinase and cellular redox signaling: beyond the DNA damage response. Trends Biochem Sci (2011) 1.91
Oxidative stress in the regulation of normal and neoplastic hematopoiesis. Antioxid Redox Signal (2008) 1.81
Expression and maintenance of mitochondrial DNA: new insights into human disease pathology. Am J Pathol (2008) 1.78
Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis. Mol Cell Biol (2010) 1.23
Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions. Blood (2013) 1.18
Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta. Genes Dev (2004) 1.14
Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice. Proc Natl Acad Sci U S A (2013) 1.12
Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells. Free Radic Biol Med (2009) 1.11
The ATM signaling network in development and disease. Front Genet (2013) 1.09
Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. Proc Natl Acad Sci U S A (2004) 1.07
Reactive oxygen species in normal and tumor stem cells. Adv Cancer Res (2014) 1.06
Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes. J Biol Chem (2009) 1.05
The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain. J Biol Chem (2010) 1.04
Ataxia-telangiectasia: future prospects. Appl Clin Genet (2014) 0.94
Reducing mitochondrial ROS improves disease-related pathology in a mouse model of ataxia-telangiectasia. Mol Ther (2012) 0.92
DNA damage response in renal ischemia-reperfusion and ATP-depletion injury of renal tubular cells. Biochim Biophys Acta (2014) 0.90
Stem cells, redox signaling, and stem cell aging. Antioxid Redox Signal (2014) 0.89
ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis. Aging (Albany NY) (2012) 0.87
DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress. PLoS Genet (2012) 0.85
ATM localization and gene expression in the adult mouse eye. Mol Vis (2009) 0.85
Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice. EMBO J (2001) 0.85
Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species. Biochem Biophys Res Commun (2012) 0.85
Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. Food Chem Toxicol (2007) 0.84
Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity. J Proteomics (2012) 0.83
ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment. Nucleic Acids Res (2014) 0.82
Experimental antioxidant therapy in ataxia telangiectasia. Clin Med Oncol (2008) 0.81
The Aspergillus nidulans ATM kinase regulates mitochondrial function, glucose uptake and the carbon starvation response. G3 (Bethesda) (2014) 0.80
DNA damage response, redox status and hematopoiesis. Blood Cells Mol Dis (2013) 0.80
ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
DNA damage: a sensible mediator of the differentiation decision in hematopoietic stem cells and in leukemia. Int J Mol Sci (2015) 0.79
Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome. Redox Biol (2016) 0.78
NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease. Proc Natl Acad Sci U S A (2015) 0.77
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells. Sci Rep (2016) 0.76
Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway. Int J Cancer (2014) 0.76
Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia. Glia (2015) 0.76
A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden. Hum Mol Genet (2015) 0.75
Oxidative stress and premature senescence in corneal endothelium following penetrating keratoplasty in an animal model. BMC Ophthalmol (2016) 0.75
Oxidative DNA Damage Response in Helicobacter pylori-Infected Mongolian Gerbils. J Cancer Prev (2013) 0.75
Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells. Nucleic Acids Res (2017) 0.75
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Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks. J Biol Chem (2001) 1.22
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