Published in EMBO J on April 02, 2001
Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. Biochemistry (2007) 1.35
Chemistry of the retinoid (visual) cycle. Chem Rev (2013) 1.28
The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target. Tuberculosis (Edinb) (2008) 1.07
Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate. Biochemistry (2008) 1.02
Mechanistic aspects of carotenoid biosynthesis. Chem Rev (2013) 1.02
Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. Toxins (Basel) (2009) 0.97
Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. J Am Chem Soc (2012) 0.79
Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse beta-carotene 15, 15'-monooxygenase. BMC Biochem (2009) 0.79
Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase from Streptococcus pneumoniae. Chembiochem (2014) 0.77
Isopentenyl-diphosphate isomerases in human and mouse: evolutionary analysis of a mammalian gene duplication. J Mol Evol (2003) 0.77
Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegypti. Insect Biochem Mol Biol (2012) 0.76
Overexpression of an isopentenyl diphosphate isomerase gene to enhance trans-polyisoprene production in Eucommia ulmoides Oliver. BMC Biotechnol (2012) 0.76
Molecular docking as a popular tool in drug design, an in silico travel. Adv Appl Bioinform Chem (2016) 0.76
Improving the catalytic activity of isopentenyl phosphate kinase through protein coevolution analysis. Sci Rep (2016) 0.75
Monoclinic form of isopentenyl diphosphate isomerase: a case of polymorphism in biomolecular crystals. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.75
The type II isopentenyl Diphosphate:Dimethylallyl diphosphate isomerase (IDI-2): A model for acid/base chemistry in flavoenzyme catalysis. Arch Biochem Biophys (2017) 0.75
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr (1998) 169.28
Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers (1983) 99.69
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature (1998) 60.62
Automated MAD and MIR structure solution. Acta Crystallogr D Biol Crystallogr (1999) 41.65
Automated protein model building combined with iterative structure refinement. Nat Struct Biol (1999) 27.52
Raster3D: photorealistic molecular graphics. Methods Enzymol (1997) 27.30
Preparation of selenomethionyl proteins for phase determination. Methods Enzymol (1997) 9.16
Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase. Science (1997) 5.56
Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. Biochem J (1993) 5.32
Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology. Science (1997) 4.63
Protein isoprenylation and methylation at carboxyl-terminal cysteine residues. Annu Rev Biochem (1992) 4.20
Creating isoprenoid diversity. Science (1997) 3.78
Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement. Proc Natl Acad Sci U S A (1997) 3.64
Structure and function of a squalene cyclase. Science (1997) 3.38
Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Annu Rev Biochem (1999) 2.72
Biosynthesis of terpenes. VII. Isopentenyl pyrophosphate isomerase. J Biol Chem (1960) 2.48
Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase. J Biol Chem (1990) 2.19
Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. J Biol Chem (1966) 2.08
The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles. Cell (1992) 1.91
Chain elongation in the isoprenoid biosynthetic pathway. Curr Opin Chem Biol (1997) 1.78
Isopentenyl diphosphate isomerase: a core enzyme in isoprenoid biosynthesis. A review of its biochemistry and function. Nat Prod Rep (1997) 1.67
Catalysis by metal-activated hydroxide in zinc and manganese metalloenzymes. Annu Rev Biochem (1999) 1.67
Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase. J Bacteriol (1999) 1.64
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase. An improved purification of the enzyme and isolation of the gene from Saccharomyces cerevisiae. J Biol Chem (1989) 1.56
Biosynthesis of carotenoids and plant triterpenes. Biochem J (1971) 1.51
The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution. J Mol Biol (1999) 1.39
Isopentenyl-diphosphate isomerase: inactivation of the enzyme with active-site-directed irreversible inhibitors and transition-state analogues. Biochemistry (1988) 1.32
Variable product specificity of microsomal dehydrodolichyl diphosphate synthase from rat liver. J Biol Chem (1991) 1.21
Mechanism of action of isopentenyl pyrophosphate isomerase: evidence for a carbonium ion intermediate. Biochemistry (1986) 1.20
Identification of Cys139 and Glu207 as catalytically important groups in the active site of isopentenyl diphosphate:dimethylallyl diphosphate isomerase. Biochemistry (1994) 1.13
Open reading frame 176 in the photosynthesis gene cluster of Rhodobacter capsulatus encodes idi, a gene for isopentenyl diphosphate isomerase. J Bacteriol (1996) 1.08
Analysis of the isopentenyl diphosphate isomerase gene family from Arabidopsis thaliana. Plant Mol Biol (1998) 1.04
Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. Arch Biochem Biophys (1996) 1.02
Cloning and subcellular localization of hamster and rat isopentenyl diphosphate dimethylallyl diphosphate isomerase. A PTS1 motif targets the enzyme to peroxisomes. J Biol Chem (1997) 0.95
The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis. Biochem J (1969) 0.94
Isopentenyl-diphosphate isomerase: irreversible inhibition by 3-methyl-3,4-epoxybutyl diphosphate. Biochemistry (1992) 0.93
Nucleotide sequence of a Clarkia breweri cDNA clone of Ipi1, a gene encoding isopentenyl pyrophosphate isomerase. Plant Physiol (1995) 0.91
Isolation of Schizosaccharomyces pombe isopentenyl diphosphate isomerase cDNA clones by complementation and synthesis of the enzyme in Escherichia coli. J Biol Chem (1995) 0.90
Purification and characterization of two isoforms of isopentenyl-diphosphate isomerase from elicitor-treated Cinchona robusta cells. Eur J Biochem (1997) 0.85
Preliminary structural studies of Escherichia coli isopentenyl diphosphate isomerase. Acta Crystallogr D Biol Crystallogr (2001) 0.83
Biosynthesis and metabolism of arginine in bacteria. Microbiol Rev (1986) 5.79
Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA. J Biol Chem (1999) 3.43
Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase. Nat Struct Biol (2000) 2.97
The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site. Cell (1999) 2.74
The occurrence of a catabolic and an anabolic ornithine carbamoyltransferase in Pseudomonas. Biochim Biophys Acta (1967) 2.12
The dual genetic control of ornithine carbamolytransferase in Escherichia coli. A case of bacterial hybrid enzymes. Eur J Biochem (1972) 2.11
Transfer RNA-mediated editing in threonyl-tRNA synthetase. The class II solution to the double discrimination problem. Cell (2000) 2.05
Regulation of enzyme synthesis in the arginine deiminase pathway of Pseudomonas aeruginosa. J Bacteriol (1980) 2.01
Catabolism of L-arginine by Pseudomonas aeruginosa. J Gen Microbiol (1980) 1.98
The arcABDC gene cluster, encoding the arginine deiminase pathway of Bacillus licheniformis, and its activation by the arginine repressor argR. J Bacteriol (1998) 1.72
Resistance profile and cross-resistance of HIV-1 among patients failing a non-nucleoside reverse transcriptase inhibitor-containing regimen. J Med Virol (2001) 1.68
Control of enzyme synthesis in the arginine deiminase pathway of Streptococcus faecalis. J Bacteriol (1982) 1.66
Differences of nucleotide stacking patterns in a crystal and in binary complexes--the case of adenine. Biopolymers (1974) 1.47
Sequence analysis and expression of the arginine-deiminase and carbamate-kinase genes of Pseudomonas aeruginosa. Eur J Biochem (1989) 1.41
Ornithine carbamoyltransferase from Escherichia coli W. Purification, structure and steady-state kinetic analysis. Eur J Biochem (1976) 1.36
Structure and function of ornithine carbamoyltransferases. Eur J Biochem (1977) 1.35
The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures. Proc Natl Acad Sci U S A (1998) 1.34
Oxygen and nitrate in utilization by Bacillus licheniformis of the arginase and arginine deiminase routes of arginine catabolism and other factors affecting their syntheses. J Bacteriol (1978) 1.33
Regulation of the catabolic ornithine carbamoyltransferase of Pseudomonas fluorescens. A comparison with the anabolic transferase and with a mutationally modified catabolic transferase. Eur J Biochem (1972) 1.28
Arginine degradation in Pseudomonas aeruginosa mutants blocked in two arginine catabolic pathways. Mol Gen Genet (1984) 1.27
Structure and properties of the putrescine carbamoyltransferase of Streptococcus faecalis. Eur J Biochem (1979) 1.27
Molecular cloning of the Escherichia coli miaA gene involved in the formation of delta 2-isopentenyl adenosine in tRNA. J Bacteriol (1988) 1.27
Escherichia coli ornithine carbamolytransferase isoenzymes: evolutionary significance and the isolation of lambdaargF and lambdaargI transducing bacteriophages. J Bacteriol (1976) 1.27
The specialization of the two ornithine carbamoyltransferases of Pseudomonas. Biochim Biophys Acta (1967) 1.25
Guanosine modifications in runoff transcripts of synthetic transfer RNA-Phe genes microinjected into Xenopus oocytes. Biochim Biophys Acta (1990) 1.25
Genetic and physiological characterization of Pseudomonas aeruginosa mutants affected in the catabolic ornithine carbamoyltransferase. J Bacteriol (1979) 1.24
Identification of clones carrying an E. coli tRNAPhe gene by suppression of phenylalanyl-tRNA synthetase thermosensitive mutants. Nucleic Acids Res (1983) 1.24
Comparison of the N-terminal sequences of aspartate and ornithine carbamoyltransferases of Escherichia coli. FEBS Lett (1977) 1.23
Mapping of the arginine deiminase gene in Pseudomonas aeruginosa. J Bacteriol (1982) 1.21
L-arginine utilization by Pseudomonas species. J Gen Microbiol (1984) 1.20
Primary and quaternary structure of the catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa. Extensive sequence homology with the anabolic ornithine carbamoyltransferases of Escherichia coli. Eur J Biochem (1987) 1.19
N-Succinylated intermediates in an arginine catabolic pathway of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1986) 1.18
Structural and regulatory mutations allowing utilization of citrulline or carbamoylaspartate as a source of carbamoylphosphate in Escherichia coli K-12. J Bacteriol (1976) 1.17
Evidence that pheV, a gene for tRNAPhe of E. coli is transcribed from tandem promoters. Nucleic Acids Res (1985) 1.16
Anabolic ornithine carbamoyltransferase of Pseudomonas aeruginosa: nucleotide sequence and transcriptional control of the argF structural gene. J Bacteriol (1988) 1.16
Structural and phylogenetic relationships among plant and animal cystatins. Arch Biochem Biophys (1998) 1.14
Enzymatic conversion of guanosine 3' adjacent to the anticodon of yeast tRNAPhe to N1-methylguanosine and the wye nucleoside: dependence on the anticodon sequence. EMBO J (1987) 1.14
Crystal structure of Pseudomonas aeruginosa catabolic ornithine transcarbamoylase at 3.0-A resolution: a different oligomeric organization in the transcarbamoylase family. Proc Natl Acad Sci U S A (1995) 1.11
The arginine deiminase pathway in Rhizobium etli: DNA sequence analysis and functional study of the arcABC genes. J Bacteriol (1997) 1.11
Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1990) 1.10
Enzymes of agmatine degradation and the control of their synthesis in Streptococcus faecalis. J Bacteriol (1982) 1.10
Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia. J Bacteriol (1985) 1.09
Enzymatic 2'-O-methylation of the wobble nucleoside of eukaryotic tRNAPhe: specificity depends on structural elements outside the anticodon loop. EMBO J (1986) 1.09
Regulation of anaerobic arginine catabolism in Bacillus licheniformis by a protein of the Crp/Fnr family. FEMS Microbiol Lett (2000) 1.07
Involvement of the cyclic AMP-responsive element binding protein in bovine leukemia virus expression in vivo. J Virol (1994) 1.07
The duplication of arginine catabolism and the meaning of the two ornithine carbamoyltransferases in Bacillus licheniformis. Biochem Biophys Res Commun (1975) 1.05
Isolation and characterization of Pseudomonas putida mutants affected in arginine, ornithine and citrulline catabolism: function of the arginine oxidase and arginine succinyltransferase pathways. J Gen Microbiol (1991) 1.03
Structure determination of the extracellular xylanase from Geobacillus stearothermophilus by selenomethionyl MAD phasing. Acta Crystallogr D Biol Crystallogr (2004) 1.02
Interaction energies in hydrogen-bonded purine-pyrimidine triplets. Proc Natl Acad Sci U S A (1967) 1.02
[On the existence of 2 ornithine transcarbamylases in a strain of Pseudomonas]. Arch Int Physiol Biochim (1965) 1.02
In vivo deuteration of transfer RNAs: overexpression and large-scale purification of deuterated specific tRNAs. Nucleic Acids Res (1996) 1.01
Yeast argininosuccinate synthetase. Purification; structural and kinetic properties. Eur J Biochem (1979) 1.00
Crystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family. Structure (2000) 0.99
Amplification of a novel gene, sanA, abolishes a vancomycin-sensitive defect in Escherichia coli. J Bacteriol (1996) 0.99
Theoretical study on the proton chemical shifts of hydrogen bonded nucleic acid bases. Nucleic Acids Res (1977) 0.98
Characterization and functional properties of the alpha-amylase inhibitor (alpha-AI) from kidney bean (Phaseolus vulgaris) seeds. Biochim Biophys Acta (1997) 0.96
Tumor necrosis factor-alpha mRNA remains unstable and hypoadenylated upon stimulation of macrophages by lipopolysaccharides. Eur J Biochem (2000) 0.96
Cellular pathways involved in the ex vivo expression of bovine leukemia virus. J Virol (1996) 0.96
The Escherichia coli threonyl-tRNA synthetase gene contains a split ribosomal binding site interrupted by a hairpin structure that is essential for autoregulation. Mol Microbiol (1998) 0.95
Regulation of the catabolic ornithine carbamoyltransferase of Pseudomonas fluorescens. A study of the allosteric interactions. Eur J Biochem (1972) 0.94
A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi. Structure (2000) 0.94
Crystal structure of the C67A mutant of isopentenyl diphosphate isomerase complexed with a mechanism-based irreversible inhibitor. Proteins (2004) 0.94
Translation of the human c-myc P0 tricistronic mRNA involves two independent internal ribosome entry sites. Oncogene (2001) 0.92
Catabolic ornithine carbamoyltransferase of Pseudomonas aeruginosa. Importance of the N-terminal region for dodecameric structure and homotropic carbamoylphosphate cooperativity. Eur J Biochem (1996) 0.92
Converting catabolic ornithine carbamoyltransferase to an anabolic enzyme. J Biol Chem (1990) 0.92
Evolutionary relationships among bacterial carbamoyltransferases. J Gen Microbiol (1989) 0.92
The specificity of translational control switched with transfer RNA identity rules. Science (1992) 0.91
Comparative studies on the degradation of guanidino and ureido compounds by Pseudomonas. J Gen Microbiol (1990) 0.91
Regulation of the catabolic ornithine carbamoyltransferase of Pseudomonas fluorescens. A study of the quaternary structure. Eur J Biochem (1972) 0.90
N2-succinylornithine in ornithine catabolism of Pseudomonas aeruginosa. Arch Microbiol (1988) 0.90
Purification and properties of a succinyltransferase from Pseudomonas aeruginosa specific for both arginine and ornithine. Eur J Biochem (1994) 0.90
An interferon regulatory factor binding site in the U5 region of the bovine leukemia virus long terminal repeat stimulates Tax-independent gene expression. J Virol (1998) 0.90
Biochemical characterisation of ornithine carbamoyltransferase from Pyrococcus furiosus. Eur J Biochem (1997) 0.89
Steady-state kinetics and analysis of pH dependence on wild-type and a modified allosteric Pseudomonas aeruginosa ornithine carbamoyltransferase containing the replacement of glutamate 105 by alanine. Eur J Biochem (1993) 0.89
Control of transcarbamoylation in micro-organisms. Symp Soc Exp Biol (1973) 0.88
Microbial life at high temperature, the challenges, the strategies. Cell Mol Life Sci (2005) 0.88
The expression of E.coli threonyl-tRNA synthetase is regulated at the translational level by symmetrical operator-repressor interactions. EMBO J (1996) 0.88
Van der Waals-London interactions between stacked purines and pyrimidines. J Theor Biol (1966) 0.88
Anabolic ornithine carbamolytransferase of Pseudomonas. The bases of its functional specialization. Eur J Biochem (1977) 0.88
Serine 948 and threonine 1042 are crucial residues for allosteric regulation of Escherichia coli carbamoylphosphate synthetase and illustrate coupling effects of activation and inhibition pathways. J Mol Biol (1999) 0.88
Molecular cloning, characterization and purification of ornithine carbamoyltransferase from Mycobacterium bovis BCG. Mol Gen Genet (1992) 0.87
Domains of the Escherichia coli threonyl-tRNA synthetase translational operator and their relation to threonine tRNA isoacceptors. J Mol Biol (1992) 0.87
Structure-based mechanism of ligand binding for periplasmic solute-binding protein of the Bug family. J Mol Biol (2007) 0.86
Molecular size and symmetry of Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase. An X-ray crystallography analysis. J Mol Biol (1991) 0.86