Published in Heart Fail Rev on March 01, 2001
Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci U S A (2002) 3.13
Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect. Atherosclerosis (2011) 1.59
Modulation of cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice. J Physiol (2003) 1.36
Endothelium-driven myocardial growth or nitric oxide at the crossroads. Trends Cardiovasc Med (2008) 0.86
Quality control systems in cardiac aging. Ageing Res Rev (2015) 0.83
Nitric oxide and cardiovascular protection. Heart Fail Rev (2003) 0.77
Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: the role of different gasotransmitters. Biomed Res Int (2013) 0.76
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell (1995) 7.13
Apoptosis in the failing human heart. N Engl J Med (1997) 6.35
Apoptosis in myocytes in end-stage heart failure. N Engl J Med (1996) 6.19
Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science (1992) 3.80
Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell (1999) 3.76
Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study. Circulation (1996) 3.28
Nitric oxide synthase activities in human myocardium. Lancet (1993) 2.72
Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res (1994) 2.64
Enteroviral protease 2A cleaves dystrophin: evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nat Med (1999) 2.50
Expression of inducible nitric oxide synthase in human heart failure. Circulation (1996) 2.26
Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog. Circ Res (1998) 2.16
Enzymatic function of nitric oxide synthases. Cardiovasc Res (1999) 2.10
Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium. Br J Pharmacol (1992) 2.09
Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide. J Biol Chem (1997) 1.97
Endomyocardial nitric oxide synthase and left ventricular preload reserve in dilated cardiomyopathy. Circulation (1999) 1.96
Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts. J Clin Invest (1998) 1.96
Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart. J Clin Invest (1993) 1.94
Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production. Circulation (1999) 1.89
Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ Res (1999) 1.81
Differential expression of tissue inhibitors of metalloproteinases in the failing human heart. Circulation (1998) 1.68
Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy. Relation to symptoms and prognosis. Circulation (1994) 1.64
Nitric oxide as a bifunctional regulator of apoptosis. Circ Res (1999) 1.63
Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans. Assessment by bicoronary sodium nitroprusside infusion. Circulation (1994) 1.62
Nitric oxide attenuates cardiac myocyte contraction. Am J Physiol (1993) 1.62
Matrix metalloproteinase inhibition during the development of congestive heart failure : effects on left ventricular dimensions and function. Circ Res (1999) 1.58
Role of nitric oxide in the regulation of oxygen consumption in conscious dogs. Circ Res (1994) 1.57
8-bromo-cGMP reduces the myofilament response to Ca2+ in intact cardiac myocytes. Circ Res (1994) 1.55
Endothelium-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy. Circulation (1990) 1.42
Factors released from endocardium of the ferret and pig modulate myocardial contraction. J Physiol (1991) 1.39
Restrictive left ventricular filling pattern in dilated cardiomyopathy assessed by Doppler echocardiography: clinical, echocardiographic and hemodynamic correlations and prognostic implications. Heart Muscle Disease Study Group. J Am Coll Cardiol (1993) 1.39
Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy. J Mol Cell Cardiol (1999) 1.38
Left ventricular systolic and diastolic dysfunction after infusion of tumor necrosis factor-alpha in conscious dogs. J Clin Invest (1992) 1.29
Mechanical transduction of nitric oxide synthesis in the beating heart. Circ Res (1997) 1.27
Sphingosine mediates the immediate negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian cardiac myocyte. J Biol Chem (1997) 1.23
Myocardial contractile response to nitric oxide and cGMP. Circulation (1996) 1.19
The role of cell death in heart failure. Circ Res (1999) 1.19
Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs. Circ Res (1993) 1.16
Molecular regulation of the bovine endothelial cell nitric oxide synthase by transforming growth factor-beta 1. Arterioscler Thromb Vasc Biol (1995) 1.15
Nitric oxide inhibits creatine kinase and regulates rat heart contractile reserve. Proc Natl Acad Sci U S A (1996) 1.15
Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x. Circ Res (1999) 1.15
Gene expression of antioxidative enzymes in the human heart: increased expression of catalase in the end-stage failing heart. Circulation (2000) 1.14
Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds. Circulation (1998) 1.14
Existence of the Frank-Starling mechanism in the failing human heart. Investigations on the organ, tissue, and sarcomere levels. Circulation (1996) 1.12
Increased sensitivity to nitric oxide synthase inhibition in patients with heart failure: potentiation of beta-adrenergic inotropic responsiveness. Circulation (1998) 1.11
Serum from patients with severe heart failure downregulates eNOS and is proapoptotic: role of tumor necrosis factor-alpha. Circulation (1999) 1.10
Nitric oxide inhibits the positive inotropic response to beta-adrenergic stimulation in humans with left ventricular dysfunction. Circulation (1995) 1.09
Proinflammatory cytokines depress cardiac efficiency by a nitric oxide-dependent mechanism. Am J Physiol (1998) 1.09
The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta. J Clin Invest (1995) 1.05
Nitric oxide modulates mitochondrial respiration in failing human heart. Circulation (1999) 1.03
Expression, activity and functional significance of inducible nitric oxide synthase in the failing human heart. J Am Coll Cardiol (1998) 1.02
Inducible nitric oxide synthase and tumor necrosis factor-alpha in myocardium in human dilated cardiomyopathy. J Am Coll Cardiol (1997) 1.02
Effect of endogenous natriuretic peptide system on ventricular and coronary function in failing heart. Am J Physiol (1997) 1.02
Chronic N(G)-nitro-L-arginine methyl ester-induced hypertension : novel molecular adaptation to systolic load in absence of hypertrophy. Circulation (2000) 1.01
Heterogeneous expression and activity of endothelial and inducible nitric oxide synthases in end-stage human heart failure: their relation to lesion site and beta-adrenergic receptor therapy. Circulation (1998) 1.01
Effect of NO donors on LV diastolic function in patients with severe pressure-overload hypertrophy. Circulation (1999) 1.01
Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis. Circulation (1999) 1.01
Effects of the nitric oxide donor sodium nitroprusside on intracellular pH and contraction in hypertrophied myocytes. Circulation (1997) 0.99
Basal release of nitric oxide augments the Frank-Starling response in the isolated heart. Circulation (1997) 0.99
Tumor necrosis factor-alpha induces a biphasic effect on myocardial contractility in conscious dogs. Circ Res (1996) 0.98
Increased expression of constitutive nitric oxide synthase III, but not inducible nitric oxide synthase II, in human heart failure. J Am Coll Cardiol (1998) 0.95
Paracrine coronary endothelial control of left ventricular function in humans. Circulation (1995) 0.95
Expression of inducible nitric oxide synthase in rat experimental autoimmune myocarditis with special reference to changes in cardiac hemodynamics. Circ Res (1997) 0.94
Coronary microvascular endothelial cell redox state in left ventricular hypertrophy : the role of angiotensin II. Circ Res (2000) 0.94
Increased activity of constitutive nitric oxide synthase in cardiac endothelium in spontaneous hypertension. Circulation (1995) 0.93
Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle. Circulation (1996) 0.91
Nitric oxide synthase (NOS3) and contractile responsiveness to adrenergic and cholinergic agonists in the heart. Regulation of NOS3 transcription in vitro and in vivo by cyclic adenosine monophosphate in rat cardiac myocytes. J Clin Invest (1996) 0.91
Atriopeptin III induces early relaxation of isolated mammalian papillary muscle. Circ Res (1988) 0.90
cGMP and atrial natriuretic factor regulate cell volume of rabbit atrial myocytes. Circ Res (1995) 0.90
Myocardial glucose uptake is regulated by nitric oxide via endothelial nitric oxide synthase in Langendorff mouse heart. Circ Res (2000) 0.89
cAMP enhances inducible nitric oxide synthase mRNA stability in cardiac myocytes. Am J Physiol (1995) 0.89
Impaired endothelium-dependent regulation of ventricular relaxation in pressure-overload cardiac hypertrophy. Circulation (2000) 0.87
Regulation by cAMP of post-translational processing and subcellular targeting of endothelial nitric-oxide synthase (type 3) in cardiac myocytes. J Biol Chem (1997) 0.87
Improvement of endocardial and vascular endothelial function on myocardial performance by captopril treatment in postinfarct rat hearts. Circulation (1999) 0.86
Cytokine-stimulated nitric oxide production inhibits mitochondrial activity in cardiac myocytes. Biochem Biophys Res Commun (1995) 0.84
Left ventricular adaptation to chronic pressure overload induced by inhibition of nitric oxide synthase in rats. Basic Res Cardiol (1998) 0.83
Ischemic cardiomyopathy: endomyocardial biopsy and ventriculographic evaluation of patients with congestive heart failure, dilated cardiomyopathy and coronary artery disease. J Am Coll Cardiol (1992) 0.82
Nitric oxide spares myocardial oxygen consumption through attenuation of contractile response to beta-adrenergic stimulation in patients with idiopathic dilated cardiomyopathy. Circulation (2000) 0.82
Increased production of nitric oxide in coronary arteries during congestive heart failure. J Clin Invest (1994) 0.81
C-Myc expression and its role in patients with chronic aortic regurgitation. Circulation (1997) 0.81
Beneficial effects of amlodipine in a murine model of congestive heart failure induced by viral myocarditis. A possible mechanism through inhibition of nitric oxide production. Circulation (1997) 0.81
Role of myocyte nitric oxide in beta-adrenergic hyporesponsiveness in heart failure. Circulation (1997) 0.80
Molecular inotropy: a future approach to the treatment of heart failure? Circulation (1999) 0.79
Left ventricular contractile effects of inducible nitric oxide synthase in the human allograft. Circulation (1997) 0.78
Nitrovasodilators have (small) direct effects on cardiac contractility: is this important? Circulation (1997) 0.77
Dobutamine enhances cardiodepressant effects of receptor-mediated coronary endothelial stimulation. Circulation (1997) 0.77
Peroxynitrite, the breakdown product of nitric oxide, is beneficial in blood cardioplegia but injurious in crystalloid cardioplegia. Circulation (1999) 0.77
Effect of endurance training on atrial natriuretic peptide gene expression in normal and hypertrophied hearts. J Appl Physiol (1985) (1994) 0.76
Lipopolysaccharide induces cell shrinkage in rabbit ventricular cardiac myocytes. Am J Physiol (1997) 0.75