Published in Semin Cancer Biol on April 01, 2001
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors. Arthritis Res (2001) 3.24
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion. Semin Cancer Biol (2010) 2.75
Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. J Cell Biol (2003) 2.12
Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells. Proc Natl Acad Sci U S A (2003) 1.91
The tumor microenvironment is a dominant force in multidrug resistance. Drug Resist Updat (2012) 1.77
Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis. Proc Natl Acad Sci U S A (2007) 1.63
MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer. Cancer Metastasis Rev (2008) 1.34
MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices. J Cell Sci (2009) 1.33
Dendritic cells and tumor microenvironment: a dangerous liaison. Immunol Invest (2006) 1.26
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. Mol Cancer (2006) 1.22
Phenotypic and genetic alterations in mammary stroma: implications for tumour progression. Breast Cancer Res (2001) 1.21
MEK4 function, genistein treatment, and invasion of human prostate cancer cells. J Natl Cancer Inst (2009) 1.20
Electrical impedance of acupuncture meridians: the relevance of subcutaneous collagenous bands. PLoS One (2010) 1.16
Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. Carcinogenesis (2012) 1.15
Increased furin activity enhances the malignant phenotype of human head and neck cancer cells. Am J Pathol (2003) 1.12
Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions. Pediatr Res (2008) 1.10
A new dawn for the use of traditional Chinese medicine in cancer therapy. Mol Cancer (2009) 1.10
TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells. Oncotarget (2013) 1.08
New Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies. Biochem Res Int (2010) 1.07
Human lung cancer cells grown in an ex vivo 3D lung model produce matrix metalloproteinases not produced in 2D culture. PLoS One (2012) 1.07
Endoglin suppresses human prostate cancer metastasis. Clin Exp Metastasis (2010) 1.04
Transcriptional analyses of Barrett's metaplasia and normal upper GI mucosae. Neoplasia (2002) 1.03
Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration. Neoplasia (2005) 1.01
Endogenous angiogenesis inhibitor blocks tumor growth via direct and indirect effects on tumor microenvironment. Am J Pathol (2011) 1.00
Anti-tumor effects of Mfn2 in gastric cancer. Int J Mol Sci (2013) 0.97
Pericyte-like location of GFP-tagged melanoma cells: ex vivo and in vivo studies of extravascular migratory metastasis. Am J Pathol (2004) 0.97
Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer. J Immunol (2013) 0.96
Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck. J Biomed Sci (2010) 0.95
Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kappa B activity leading to apoptosis in breast tumors. Clin Cancer Res (2008) 0.95
Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer. BMC Cancer (2008) 0.94
Using real-time impedance-based assays to monitor the effects of fibroblast-derived media on the adhesion, proliferation, migration and invasion of colon cancer cells. Biosci Rep (2014) 0.93
Heparanase activity in alveolar and embryonal rhabdomyosarcoma: implications for tumor invasion. BMC Cancer (2009) 0.92
Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers. Breast Cancer Res (2015) 0.92
Inhibitory Effects of Terminalia catappa on UVB-Induced Photodamage in Fibroblast Cell Line. Evid Based Complement Alternat Med (2010) 0.91
The inflammatory network: bridging senescent stroma and epithelial tumorigenesis. Front Biosci (Landmark Ed) (2009) 0.89
Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification. Am J Pathol (2001) 0.89
Barriers to drug delivery in solid tumors. Tissue Barriers (2014) 0.89
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells. PLoS One (2011) 0.88
Matrix metalloproteinase-9 overexpression is closely related to poor prognosis in patients with colon cancer. World J Surg Oncol (2014) 0.88
Role of proteolytic enzymes in human prostate bone metastasis formation: in vivo and in vitro studies. Br J Cancer (2002) 0.87
TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells. Oncotarget (2013) 0.86
Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5. Genomics Inform (2014) 0.85
Meta-analysis of MMP2, MMP3, and MMP9 promoter polymorphisms and head and neck cancer risk. PLoS One (2013) 0.84
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. J Mol Histol (2010) 0.84
Development of inductively coupled plasma-mass spectrometry-based protease assays. Anal Biochem (2009) 0.83
Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression. Oncotarget (2014) 0.83
Fermentation supernatants of Lactobacillus delbrueckii inhibit growth of human colon cancer cells and induce apoptosis through a caspase 3-dependent pathway. Oncol Lett (2014) 0.83
The MMP-1, MMP-2, and MMP-9 gene polymorphisms and susceptibility to bladder cancer: a meta-analysis. Tumour Biol (2014) 0.82
N-cadherin knock-down decreases invasiveness of esophageal squamous cell carcinoma in vitro. World J Gastroenterol (2009) 0.82
Association between MMP1 -1607 1G>2G polymorphism and head and neck cancer risk: a meta-analysis. PLoS One (2013) 0.81
Semaphorin7A Promotion of Tumoral Growth and Metastasis in Human Oral Cancer by Regulation of G1 Cell Cycle and Matrix Metalloproteases: Possible Contribution to Tumoral Angiogenesis. PLoS One (2015) 0.81
Proteinases and their inhibitors in liver cancer. World J Hepatol (2009) 0.81
P-cadherin counteracts myosin II-B function: implications in melanoma progression. Mol Cancer (2010) 0.81
Inflammatory cytokines induce vascular endothelial growth factor-C expression in melanoma-associated macrophages and stimulate melanoma lymph node metastasis. Oncol Lett (2014) 0.81
Detection of protease activities by flash chronopotentiometry using a reversible polycation-sensitive polymeric membrane electrode. Anal Biochem (2011) 0.80
Isoflavonoid-Rich Flemingia macrophylla Extract Attenuates UVB-Induced Skin Damage by Scavenging Reactive Oxygen Species and Inhibiting MAP Kinase and MMP Expression. Evid Based Complement Alternat Med (2013) 0.80
Expression of matrix metalloproteinase-1, -9, -13, and tissue inhibitor of metalloproteinases-1 in basal cell carcinomas of the eyelid. Graefes Arch Clin Exp Ophthalmol (2011) 0.79
Rosiglitazone Suppresses the Growth and Invasiveness of SGC-7901 Gastric Cancer Cells and Angiogenesis In Vitro via PPARgamma Dependent and Independent Mechanisms. PPAR Res (2008) 0.79
A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4. PLoS One (2013) 0.78
Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasis. Cancer Sci (2015) 0.78
Effects of cyclooxygenase-2 gene silencing on the biological behavior of SKOV3 ovarian cancer cells. Mol Med Rep (2014) 0.78
Impact of the prolymphangiogenic crosstalk in the tumor microenvironment on lymphatic cancer metastasis. Biomed Res Int (2014) 0.77
The FBI1/Akirin2 target gene, BCAM, acts as a suppressive oncogene. PLoS One (2013) 0.77
Soy isoflavones and cellular mechanics. J Bioenerg Biomembr (2013) 0.76
Downregulation of feline sarcoma-related protein inhibits cell migration, invasion and epithelial-mesenchymal transition via the ERK/AP-1 pathway in bladder urothelial cell carcinoma. Oncol Lett (2016) 0.75
IL-1β promotes proliferation and migration of gallbladder cancer cells via Twist activation. Oncol Lett (2016) 0.75
The expression and clinical significance of matrix metalloproteinase 7 and tissue inhibitor of matrix metalloproteinases 2 in clear cell renal cell carcinoma. Exp Ther Med (2012) 0.75
Are macrophages in tumors good targets for novel therapeutic approaches? Mol Cells (2014) 0.75
Association between matrix metalloproteinase 1 -1607 1G>2G polymorphism and cancer risk: a meta-analysis including 19706 subjects. Int J Clin Exp Med (2014) 0.75
Bisphosphonates in multicentric osteolysis, nodulosis and arthropathy (MONA) spectrum disorder - an alternative therapeutic approach. Sci Rep (2016) 0.75
Effect of small interfering RNAs on matrix metalloproteinase 1 expression. Biotechnol Rep (Amst) (2014) 0.75
Pathology of Perineural Spread. J Neurol Surg B Skull Base (2016) 0.75
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death Through its Carboxyterminal Domain. Am J Respir Crit Care Med (2017) 0.75
Effect of quinolinyl acrylate derivatives on prostate cancer in vitro and in vivo. Invest New Drugs (2011) 0.75
Multiple receptor-ligand based pharmacophore modeling and molecular docking to screen the selective inhibitors of matrix metalloproteinase-9 from natural products. J Comput Aided Mol Des (2017) 0.75
Variable forms of soluble guanylyl cyclase: protein-ligand interactions and the issue of activation by carbon monoxide. J Biol Inorg Chem (1999) 0.90
Reconstructed 19 kDa catalytic domain of gelatinase A is an active proteinase. Biochemistry (1995) 0.85