Published in Ann Noninvasive Electrocardiol on April 01, 2001
Long QT Syndrome-Population Genetics and Cardiac Studies (LQTS) | NCT00005176
Inherited disorders of voltage-gated sodium channels. J Clin Invest (2005) 3.29
Long QT syndrome: from channels to cardiac arrhythmias. J Clin Invest (2005) 2.71
Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndrome. J Cardiovasc Electrophysiol (2008) 2.39
Ionic, molecular, and cellular bases of QT-interval prolongation and torsade de pointes. Europace (2007) 1.57
Malignant perinatal variant of long-QT syndrome caused by a profoundly dysfunctional cardiac sodium channel. Circ Arrhythm Electrophysiol (2008) 1.53
Importance of Knowing the Genotype and the Specific Mutation When Managing Patients with Long QT Syndrome. Circ Arrhythm Electrophysiol (2008) 1.48
Autonomic aspects of arrhythmogenesis: the enduring and the new. Curr Opin Cardiol (2004) 1.35
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome. J Physiol (2007) 1.19
Long QT syndrome: novel insights into the mechanisms of cardiac arrhythmias. J Clin Invest (2003) 1.18
Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations. J Gen Physiol (2002) 1.17
State-dependent trapping of flecainide in the cardiac sodium channel. J Physiol (2004) 1.13
Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: I. Experimental analysis of the use-dependent block. Am J Physiol Heart Circ Physiol (2011) 1.08
Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes. Circ Res (2006) 1.07
State-dependent block of wild-type and inactivation-deficient Na+ channels by flecainide. J Gen Physiol (2003) 1.03
Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3. Cardiovasc Res (2010) 1.03
LQT4 gene: the "missing" ankyrin. Mol Interv (2003) 1.01
Recent progress in congenital long QT syndrome. Curr Opin Cardiol (2010) 0.99
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3. J Physiol (2006) 0.98
Pathophysiology of the cardiac late Na current and its potential as a drug target. J Mol Cell Cardiol (2011) 0.95
Genetics of congenital and drug-induced long QT syndromes: current evidence and future research perspectives. J Interv Card Electrophysiol (2013) 0.94
Clinical Aspects of Type 3 Long-QT Syndrome: An International Multicenter Study. Circulation (2016) 0.80
Mutation-specific risk in two genetic forms of type 3 long QT syndrome. Am J Cardiol (2010) 0.80
Long QT syndrome: A therapeutic challenge. Ann Pediatr Cardiol (2008) 0.76
Murine Electrophysiological Models of Cardiac Arrhythmogenesis. Physiol Rev (2017) 0.75
Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol (1987) 9.10
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell (1995) 7.73
Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2. Circulation (2000) 7.50
Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation (2001) 7.47
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat Genet (1996) 7.35
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome. Circulation (2000) 5.09
Diagnostic criteria for the long QT syndrome. An update. Circulation (1993) 4.48
ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome. Circulation (1995) 3.79
Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group. N Engl J Med (1998) 3.41
Spectrum of ST-T-wave patterns and repolarization parameters in congenital long-QT syndrome: ECG findings identify genotypes. Circulation (2000) 2.95
Living alone after myocardial infarction. Impact on prognosis. JAMA (1992) 2.88
Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome. A worldwide report. Circulation (1991) 2.87
Age- and sex-related differences in clinical manifestations in patients with congenital long-QT syndrome: findings from the International LQTS Registry. Circulation (1998) 2.53
Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research. Circulation (1997) 2.00
Long-term nitrate use may be deleterious in ischemic heart disease: A study using the databases from two large-scale postinfarction studies. Multicenter Myocardial Ischemia Research Group. Am Heart J (1999) 1.94
Relation between ventricular repolarization duration and cardiac cycle length during 24-hour Holter recordings. Findings in normal patients and patients with long QT syndrome. Circulation (1992) 1.86
The long QT syndrome: a prospective international study. Circulation (1985) 1.77
Delay in hospitalization during the acute coronary period. Am J Cardiol (1969) 1.77
Left ventricular-right atrial communication. Am J Cardiol (1967) 1.74
Unilateral cervicothoracic sympathetic ganglionectomy for the treatment of long QT interval syndrome. N Engl J Med (1971) 1.68
Electrocardiographic quantitation of ventricular repolarization. Circulation (1989) 1.65
American Heart Association Report on the Public Access Defibrillation Conference December 8-10, 1994. Automatic External Defibrillation Task Force. Circulation (1995) 1.60
Long QT syndrome. New electrocardiographic characteristics. Circulation (1990) 1.60
Ventricular ectopic beats and their relation to sudden and nonsudden cardiac death after myocardial infarction. Circulation (1979) 1.55
New mutations in the KVLQT1 potassium channel that cause long-QT syndrome. Circulation (1998) 1.53
The cost-effectiveness of automatic implantable cardiac defibrillators: results from MADIT. Multicenter Automatic Defibrillator Implantation Trial. Circulation (1998) 1.50
The prognostic significance of first myocardial infarction type (Q wave versus non-Q wave) and Q wave location. The Multicenter Diltiazem Post-Infarction Research Group. J Am Coll Cardiol (1990) 1.48
Gender-related differences in thrombogenic factors predicting recurrent cardiac events in patients after acute myocardial infarction. The THROMBO Investigators. Am J Cardiol (2000) 1.47
Dispersion of ventricular repolarization and arrhythmic cardiac death in coronary artery disease. Am J Cardiol (1994) 1.43
Mechanism of death and prevalence of myocardial ischemic symptoms in the terminal event after acute myocardial infarction. Am J Cardiol (1988) 1.42
Prognostic value of cholesterol in women of different ages. J Womens Health (1997) 1.42
Tricuspid candida endocarditis complicating a permanently implanted transvenous pacemaker. Am Heart J (1969) 1.41
The early posthospital phase of myocardial infarction. Prognostic stratification. Circulation (1976) 1.41
Q-wave vs non-Q-wave myocardial infarction. An oversimplified dichotomy. JAMA (1992) 1.39
Relation between myocardial infarct location and stroke. J Am Coll Cardiol (1994) 1.39
Influence of pregnancy on the risk for cardiac events in patients with hereditary long QT syndrome. LQTS Investigators. Circulation (1998) 1.39
Thrombogenic factors and recurrent coronary events. Circulation (1999) 1.38
Long-term survival after mitral valve replacement in children aged <5 years: a multi-institutional study. Circulation (2001) 1.38
Correct the QT interval correctly: QTc should be expressed in the same unit as the QT interval. Pacing Clin Electrophysiol (1996) 1.38
Survivorship patterns in the posthospital phase of myocardial infarction. Circulation (1979) 1.34
Transthoracic and transvenous pacemakers. A comparative clinical experience with 131 implantable units. Br Heart J (1970) 1.33
Current estimates from the National Health Interview Survey. United States, 1985. Vital Health Stat 10 (1986) 1.31
Prolonged QT-interval syndromes. JAMA (1986) 1.31
Identification and treatment of low-risk patients after acute myocardial infarction and coronary-artery bypass graft surgery. N Engl J Med (1986) 1.29
Comparison of clinical and genetic variables of cardiac events associated with loud noise versus swimming among subjects with the long QT syndrome. Am J Cardiol (1999) 1.25
The echocardiogram. An ultrasound technic for the detection of pericardial effusion. N Engl J Med (1966) 1.23
American Heart Association report on the second public access defibrillation conference, April 17-19, 1997. Circulation (1998) 1.21
Health indicators for Hispanic, black, and white Americans. Vital Health Stat 10 (1984) 1.16
On the possibility that a type of human muscular dystrophy commences in myocardium. Ann N Y Acad Sci (1966) 1.12
Permanent pervenous atrial pacing from the coronary vein. Circulation (1970) 1.10
The electrocardiogram in normal newborn infants: correlation with hemodynamic observations. J Pediatr (1965) 1.10
Collaborative meta-analysis of individual participant data from observational studies of Lp-PLA2 and cardiovascular diseases. Eur J Cardiovasc Prev Rehabil (2007) 1.10
Implantable cardioverter defibrillator therapy: the sickest patients benefit the most. Circulation (2000) 1.09
Late onset complete heart block. Newly recognized sequela of cardiac surgery. Am J Cardiol (1972) 1.09
Blood pressure in infants children and adolescents. West J Med (1981) 1.09
Cardiovascular effects of sustained norepinephrine infusions. II. Morphology. Circ Res (1966) 1.09
Type A behavior and survival after acute myocardial infarction. N Engl J Med (1985) 1.08
The pre-hospital phase of acute myocadial infarction. Circulation (1970) 1.08
Transvenous left atrial pacing for the control of recurrent ventricular fibrillation. N Engl J Med (1968) 1.08
T wave alternans in idiopathic long QT syndrome. J Am Coll Cardiol (1994) 1.08
Long-term pervenous atrial pacing from the proximal portion of the coronary vein. JAMA (1969) 1.06
Microangiopathic hemolytic anemia and thrombocytopenia in primary pulmonary hypertension. N Engl J Med (1972) 1.06
Central venous oxygen saturations. Value of serial determinations in patients with acute myocardial infarction. JAMA (1970) 1.06
Children's exposure to environmental cigarette smoke before and after birth. Health of our nation's children, United States, 1988. Adv Data (1991) 1.06
Clinical recognition of cor pulmonale in cystic fibrosis. J Pediatr (1971) 1.04
Digitalis-associated cardiac mortality after myocardial infarction. Circulation (1981) 1.04
Polymorphism of the gene encoding a human minimal potassium ion channel (minK). Gene (1994) 1.03
Cor pulmonale in cystic fibrosis of the pancreas. J Pediatr (1965) 1.03
Atrial tachypacing in the treatment of a patient with primary orthostatic hypotension. N Engl J Med (1980) 1.03
Cardiac disease in the wheezing child. Chest (1977) 1.03
Sudden cardiac death, genes, and arrhythmogenesis : consideration of new population and mechanistic approaches from a national heart, lung, and blood institute workshop, part I. Circulation (2001) 1.01
Age-gender influence on the rate-corrected QT interval and the QT-heart rate relation in families with genotypically characterized long QT syndrome. J Am Coll Cardiol (1997) 1.01
Assistive technology devices and home accessibility features: prevalence, payment, need, and trends. Adv Data (1992) 1.01
Termination and inhibition of recurrent tachycardias by implanted pervenous pacemakers. Circulation (1974) 1.00
Risk of cardiac events in family members of patients with long QT syndrome. J Am Coll Cardiol (1995) 1.00
Anticardiolipin antibodies and recurrent coronary events: a prospective study of 1150 patients. Thrombogenic Factors, and Recurrent Coronary Events Investigators. Circulation (2000) 0.99
Is arrhythmia detection by automatic external defibrillator accurate for children?: sensitivity and specificity of an automatic external defibrillator algorithm in 696 pediatric arrhythmias. Circulation (2001) 0.98
Pacemaker management for acute onset of heart block in childhood. J Pediatr (1985) 0.98
Clinical significance of ventricular tachycardia (3 beats or longer) detected during ambulatory monitoring after myocardial infarction. Circulation (1978) 0.97
Public access defibrillation. A statement for healthcare professionals from the American Heart Association Task Force on Automatic External Defibrillation. Circulation (1995) 0.97
Interrelation of left ventricular ejection fraction, pulmonary congestion and outcome in acute myocardial infarction. Am J Cardiol (1992) 0.97
Atrial pacing from the coronary vein. Ten-year experience in 50 patients with implanted pervenous pacemakers. Circulation (1978) 0.97
Low-level exercise testing after myocardial infarction: usefulness in enhancing clinical risk stratification. Circulation (1985) 0.97
Stress and sudden death. The case of the long QT syndrome. Circulation (1991) 0.96
Congenital corrected transposition of the great vessels without cardiac anomalies. Am J Med (1969) 0.95
Prognosis after myocardial infarction. Am J Cardiol (1983) 0.95
Long QT syndrome: an indication for cervicothoracic sympathectomy. Cardiovasc Surg (1995) 0.95
Sudden death and the idiopathic long Q-T syndrome. Am J Med (1979) 0.95
Delayed repolarization (QT or QTU prolongation) and malignant ventricular arrhythmias. Mod Concepts Cardiovasc Dis (1982) 0.94
Dynamic analysis of ventricular repolarization duration from 24-hour Holter recordings. IEEE Trans Biomed Eng (1993) 0.94
Psychosis with ordinary doses of propranolol. Ann Intern Med (1979) 0.94
Symposium on the pre-hospital phase of acute myocardial infarction. I. Introduction. Am J Cardiol (1969) 0.94