Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1.

PubWeight™: 1.41‹?› | Rank: Top 5%

🔗 View Article (PMC 114908)

Published in J Virol on June 01, 2001

Authors

S Cen1, A Khorchid, H Javanbakht, J Gabor, T Stello, K Shiba, K Musier-Forsyth, L Kleiman

Author Affiliations

1: Lady Davis Institute for Medical Research and McGill AIDS Centre, Jewish General Hospital, McGill University, Montreal, Quebec, Canada H3T 1E2.

Articles citing this

The retrovirus RNA trafficking granule: from birth to maturity. Retrovirology (2006) 1.63

Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response. Proc Natl Acad Sci U S A (2005) 1.55

Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription. RNA Biol (2010) 1.35

Retrovirus-specific packaging of aminoacyl-tRNA synthetases with cognate primer tRNAs. J Virol (2002) 1.27

RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions. Nucleic Acids Res (2009) 1.22

Aminoacyl-tRNA synthetase complexes: molecular multitasking revealed. FEMS Microbiol Rev (2008) 1.17

Profiling non-lysyl tRNAs in HIV-1. RNA (2009) 1.14

Cellular distribution of Lysyl-tRNA synthetase and its interaction with Gag during human immunodeficiency virus type 1 assembly. J Virol (2004) 1.12

Formation of the tRNALys packaging complex in HIV-1. FEBS Lett (2010) 1.11

ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity. J Virol (2005) 1.08

Matrix domain modulates HIV-1 Gag's nucleic acid chaperone activity via inositol phosphate binding. J Virol (2010) 1.06

Reverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription. Viruses (2009) 1.03

Molecular mimicry of human tRNALys anti-codon domain by HIV-1 RNA genome facilitates tRNA primer annealing. RNA (2012) 0.98

Specific inhibition of the synthesis of human lysyl-tRNA synthetase results in decreases in tRNA(Lys) incorporation, tRNA(3)(Lys) annealing to viral RNA, and viral infectivity in human immunodeficiency virus type 1. J Virol (2003) 0.96

Selection of retroviral reverse transcription primer is coordinated with tRNA biogenesis. J Virol (2003) 0.93

Ability of wild-type and mutant lysyl-tRNA synthetase to facilitate tRNA(Lys) incorporation into human immunodeficiency virus type 1. J Virol (2004) 0.93

Probing the importance of tRNA anticodon: human immunodeficiency virus type 1 (HIV-1) RNA genome complementarity with an HIV-1 that selects tRNA(Glu) for replication. J Virol (2003) 0.92

Small-angle X-ray scattering-derived structure of the HIV-1 5' UTR reveals 3D tRNA mimicry. Proc Natl Acad Sci U S A (2014) 0.91

The Tat protein of human immunodeficiency virus type 1 (HIV-1) can promote placement of tRNA primer onto viral RNA and suppress later DNA polymerization in HIV-1 reverse transcription. J Virol (2002) 0.90

Insulin-like growth factor II mRNA binding protein 1 associates with Gag protein of human immunodeficiency virus type 1, and its overexpression affects virus assembly. J Virol (2008) 0.85

Viruses as modulators of mitochondrial functions. Adv Virol (2013) 0.85

Initiation of HIV Reverse Transcription. Viruses (2010) 0.85

The allosteric HIV-1 integrase inhibitor BI-D affects virion maturation but does not influence packaging of a functional RNA genome. PLoS One (2014) 0.85

Functional recognition of the modified human tRNALys3(UUU) anticodon domain by HIV's nucleocapsid protein and a peptide mimic. J Mol Biol (2011) 0.85

tRNA synthetase: tRNA aminoacylation and beyond. Wiley Interdiscip Rev RNA (2014) 0.84

Structural elements of the tRNA TPsiC loop critical for nucleocytoplasmic transport are important for human immunodeficiency virus type 1 primer selection. J Virol (2005) 0.84

Viral hijacking of mitochondrial lysyl-tRNA synthetase. J Virol (2006) 0.83

Similarities and differences in the nucleic acid chaperone activity of HIV-2 and HIV-1 nucleocapsid proteins in vitro. Retrovirology (2014) 0.80

Glyceraldehyde 3-phosphate dehydrogenase negatively regulates human immunodeficiency virus type 1 infection. Retrovirology (2012) 0.80

Synthetic tRNALys,3 as the replication primer for the HIV-1HXB2 and HIV-1Mal genomes. Nucleic Acids Res (2004) 0.79

Host RNA Packaging by Retroviruses: A Newly Synthesized Story. MBio (2016) 0.79

Dual role for motif 1 residues of human lysyl-tRNA synthetase in dimerization and packaging into HIV-1. J Biol Chem (2012) 0.78

Fate of HIV-1 cDNA intermediates during reverse transcription is dictated by transcription initiation site of virus genomic RNA. Sci Rep (2015) 0.78

Inability of human immunodeficiency virus type 1 produced in murine cells to selectively incorporate primer formula. J Virol (2008) 0.77

Binding of the eukaryotic translation elongation factor 1A with the 5'UTR of HIV-1 genomic RNA is important for reverse transcription. Virol J (2015) 0.76

Proteomics in the investigation of HIV-1 interactions with host proteins. Proteomics Clin Appl (2015) 0.75

HIV Genome-Wide Protein Associations: a Review of 30 Years of Research. Microbiol Mol Biol Rev (2016) 0.75

Analysis of RNA structure using small-angle X-ray scattering. Methods (2016) 0.75

The C-terminal domain of glyceraldehyde 3-phosphate dehydrogenase plays an important role in suppression of tRNA(Lys3) packaging into human immunodeficiency virus type-1 particles. Biochem Biophys Rep (2016) 0.75

HIV-1 exploits dynamic multi-aminoacyl-tRNA synthetase complex to enhance viral replication. J Virol (2017) 0.75

Articles cited by this

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

Human immunodeficiency virus type 1 Pr55gag and Pr160gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles. J Virol (1990) 4.22

Identification of tRNAs incorporated into wild-type and mutant human immunodeficiency virus type 1. J Virol (1993) 3.08

Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles. J Virol (1994) 2.94

Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles. J Virol (1993) 2.69

Highly purified human immunodeficiency virus type 1 reveals a virtual absence of Vif in virions. J Virol (1999) 2.66

The nonmyristylated Pr160gag-pol polyprotein of human immunodeficiency virus type 1 interacts with Pr55gag and is incorporated into viruslike particles. J Virol (1992) 2.17

A channeled tRNA cycle during mammalian protein synthesis. Proc Natl Acad Sci U S A (1995) 2.13

Translation elongation factor 1-alpha interacts specifically with the human immunodeficiency virus type 1 Gag polyprotein. J Virol (1999) 2.08

The human immunodeficiency virus type 1 Gag polyprotein has nucleic acid chaperone activity: possible role in dimerization of genomic RNA and placement of tRNA on the primer binding site. J Virol (1999) 2.04

Analysis and localization of cyclophilin A found in the virions of human immunodeficiency virus type 1 MN strain. AIDS Res Hum Retroviruses (1995) 2.01

Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1. J Mol Biol (1997) 1.58

The role of Pr55(gag) in the annealing of tRNA3Lys to human immunodeficiency virus type 1 genomic RNA. J Virol (1999) 1.49

A domain in the N-terminal extension of class IIb eukaryotic aminoacyl-tRNA synthetases is important for tRNA binding. EMBO J (2000) 1.34

Sequences within Pr160gag-pol affecting the selective packaging of primer tRNA(Lys3) into HIV-1. J Mol Biol (2000) 1.32

A component of the multisynthetase complex is a multifunctional aminoacyl-tRNA synthetase. EMBO J (1991) 1.32

Autoregulation of the yeast lysyl-tRNA synthetase gene GCD5/KRS1 by translational and transcriptional control mechanisms. Cell (1992) 1.26

Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. J Biol Chem (1997) 1.21

Effect of mutations in the nucleocapsid protein (NCp7) upon Pr160(gag-pol) and tRNA(Lys) incorporation into human immunodeficiency virus type 1. J Virol (1997) 1.19

The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript. J Biol Chem (2000) 1.13

Do yeast aminoacyl-tRNA synthetases exist as soluble enzymes within the cytoplasm? Eur J Biochem (1985) 1.06

Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. Proc Natl Acad Sci U S A (1994) 1.02

Isolation of prolyl-tRNA synthetase as a free form and as a form associated with glutamyl-tRNA synthetase. J Biol Chem (1992) 0.98

Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) interacts with Lys-tRNA synthetase: implications for priming of HIV-1 reverse transcription. J Virol (1998) 0.94

Leucyl-tRNA and lysyl-tRNA synthetases, derived from the high-Mr complex of sheep liver, are hydrophobic proteins. Eur J Biochem (1985) 0.92

An elongation factor-associating domain is inserted into human cysteinyl-tRNA synthetase by alternative splicing. Nucleic Acids Res (2000) 0.90

Articles by these authors

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science (1997) 4.62

A defined mutation in the protein export gene within the spc ribosomal protein operon of Escherichia coli: isolation and characterization of a new temperature-sensitive secY mutant. EMBO J (1984) 3.43

A temperature-sensitive mutant of E. coli exhibiting slow processing of exported proteins. Cell (1983) 3.26

Identification of tRNAs incorporated into wild-type and mutant human immunodeficiency virus type 1. J Virol (1993) 3.08

Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles. J Virol (1994) 2.94

Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication. J Virol (1994) 2.37

Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction. J Biol Chem (1994) 2.28

Association of human immunodeficiency virus type 1 Vif with RNA and its role in reverse transcription. J Virol (2000) 2.00

Primer tRNAs for reverse transcription. J Virol (1997) 1.90

Cloning, sequencing, and mapping of an alpha-actinin gene from the nematode Caenorhabditis elegans. Cell Motil Cytoskeleton (1991) 1.83

Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching. Proc Natl Acad Sci U S A (2001) 1.69

Mutations in the kissing-loop hairpin of human immunodeficiency virus type 1 reduce viral infectivity as well as genomic RNA packaging and dimerization. J Virol (1997) 1.68

Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site. J Virol (1996) 1.68

Suppressors of the secY24 mutation: identification and characterization of additional ssy genes in Escherichia coli. J Bacteriol (1986) 1.66

Hydrolytic editing by a class II aminoacyl-tRNA synthetase. Proc Natl Acad Sci U S A (2000) 1.61

Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1. J Mol Biol (1997) 1.58

A mutation that enhances synthesis of sigma 32 and suppresses temperature-sensitive growth of the rpoH15 mutant of Escherichia coli. J Bacteriol (1990) 1.57

Transforming growth factor beta type II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer. Gastroenterology (1997) 1.53

Transfer RNA recognition by aminoacyl-tRNA synthetases. Biopolymers (1999) 1.53

The role of Pr55(gag) in the annealing of tRNA3Lys to human immunodeficiency virus type 1 genomic RNA. J Virol (1999) 1.49

Incorporation of excess wild-type and mutant tRNA(3Lys) into human immunodeficiency virus type 1. J Virol (1994) 1.49

The role of nucleocapsid and U5 stem/A-rich loop sequences in tRNA(3Lys) genomic placement and initiation of reverse transcription in human immunodeficiency virus type 1. J Virol (1998) 1.47

Sequence determination and modeling of structural motifs for the smallest monomeric aminoacyl-tRNA synthetase. Proc Natl Acad Sci U S A (1991) 1.46

The secY protein can act post-translationally to promote bacterial protein export. J Biol Chem (1986) 1.44

Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcription. J Virol (1996) 1.42

Mutation that suppresses the protein export defect of the secY mutation and causes cold-sensitive growth of Escherichia coli. J Bacteriol (1984) 1.42

Genetic dissection of protein-protein interactions in multi-tRNA synthetase complex. Proc Natl Acad Sci U S A (1999) 1.40

The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity. J Virol (1997) 1.37

Positive and negative regulations of plasmid CoLIb-P9 repZ gene expression at the translational level. J Biol Chem (1991) 1.36

Preferential interaction of human immunodeficiency virus reverse transcriptase with two regions of primer tRNA(Lys) as evidenced by footprinting studies and inhibition with synthetic oligoribonucleotides. J Mol Biol (1992) 1.35

Variable tRNA content in HIV-1IIIB. Biochem Biophys Res Commun (1992) 1.34

Correlation between the bronchial subepithelial layer and whole airway wall thickness in patients with asthma. Thorax (2002) 1.32

DNA found in human immunodeficiency virus type 1 particles may not be required for infectivity. J Gen Virol (1994) 1.32

Sequences within Pr160gag-pol affecting the selective packaging of primer tRNA(Lys3) into HIV-1. J Mol Biol (2000) 1.32

Compensatory point mutations in the human immunodeficiency virus type 1 Gag region that are distal from deletion mutations in the dimerization initiation site can restore viral replication. J Virol (1998) 1.31

Diverse effects of the MalE-LacZ hybrid protein on Escherichia coli cell physiology. J Bacteriol (1986) 1.27

Insertional disruption of the nusB (ssyB) gene leads to cold-sensitive growth of Escherichia coli and suppression of the secY24 mutation. Mol Gen Genet (1992) 1.24

Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. J Biol Chem (1997) 1.21

Interaction between human tRNA synthetases involves repeated sequence elements. Proc Natl Acad Sci U S A (1996) 1.21

Primer tRNA3Lys on the viral genome exists in unextended and two-base extended forms within mature human immunodeficiency virus type 1. J Virol (1997) 1.20

Effect of mutations in the nucleocapsid protein (NCp7) upon Pr160(gag-pol) and tRNA(Lys) incorporation into human immunodeficiency virus type 1. J Virol (1997) 1.19

Inositol monophosphatase activity from the Escherichia coli suhB gene product. J Bacteriol (1995) 1.18

Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase. J Biol Chem (1999) 1.18

Outcome of decompression surgery for cervical spinal cord injury without bone and disc injury in patients with spinal cord compression: a multicenter prospective study. Spinal Cord (2010) 1.18

HIV-1 nucleocapsid protein zinc finger structures induce tRNA(Lys,3) structural changes but are not critical for primer/template annealing. J Mol Biol (2001) 1.17

Escherichia coli proline tRNA synthetase is sensitive to changes in the core region of tRNA(Pro). Biochemistry (1994) 1.17

Roles of the human immunodeficiency virus type 1 nucleocapsid protein in annealing and initiation versus elongation in reverse transcription of viral negative-strand strong-stop DNA. J Virol (1998) 1.15

Deletion mutagenesis within the dimerization initiation site of human immunodeficiency virus type 1 results in delayed processing of the p2 peptide from precursor proteins. J Virol (1999) 1.14

Use of 1,2,4-dithiazolidine-3,5-dione (DtsNH) and 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) for synthesis of phosphorothioate-containing oligodeoxyribonucleotides. Nucleic Acids Res (1996) 1.12

Species-specific differences in amino acid editing by class II prolyl-tRNA synthetase. J Biol Chem (2001) 1.11

Altered translation initiation factor 2 in the cold-sensitive ssyG mutant affects protein export in Escherichia coli. EMBO J (1986) 1.11

Role of zinc ion in translational accuracy becomes crystal clear. Nat Struct Biol (2000) 1.09

Intra-tRNA distance measurements for nucleocapsid proteindependent tRNA unwinding during priming of HIV reverse transcription. Proc Natl Acad Sci U S A (1999) 1.08

Mutations within four distinct gag proteins are required to restore replication of human immunodeficiency virus type 1 after deletion mutagenesis within the dimerization initiation site. J Virol (1999) 1.08

Molecular recognition of tRNA(Pro) by Escherichia coli proline tRNA synthetase in vitro. Nucleic Acids Res (1995) 1.07

Roles of Pr55(gag) and NCp7 in tRNA(3)(Lys) genomic placement and the initiation step of reverse transcription in human immunodeficiency virus type 1. J Virol (2000) 1.06

Species-specific differences in the operational RNA code for aminoacylation of tRNAPro. Biochemistry (1998) 1.06

RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis. Proc Natl Acad Sci U S A (1992) 1.04

The nucleocapsid protein specifically anneals tRNALys-3 onto a noncomplementary primer binding site within the HIV-1 RNA genome in vitro. Proc Natl Acad Sci U S A (1997) 1.04

Role of distal zinc finger of nucleocapsid protein in genomic RNA dimerization of human immunodeficiency virus type 1; no role for the palindrome crowning the R-U5 hairpin. Virology (2001) 1.04

Specific atomic groups and RNA helix geometry in acceptor stem recognition by a tRNA synthetase. Proc Natl Acad Sci U S A (1997) 1.03

Molecular analysis of the second template switch during reverse transcription of the HIV RNA template. Biochemistry (1996) 1.03

Small RNA helices as substrates for aminoacylation and their relationship to charging of transfer RNAs. Eur J Biochem (1992) 1.01

Sequence elements downstream of the human immunodeficiency virus type 1 long terminal repeat are required for efficient viral gene transcription. J Mol Biol (1997) 1.01

Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen. Proc Natl Acad Sci U S A (1995) 1.01

Comparison of the base-sequence complexities of polysomal and nuclear RNAs in growing Friend erythroleukemia cells. Biochemistry (1977) 0.99

A neutrophil elastase inhibitor (ONO-5046) reduces neurologic damage after spinal cord injury in rats. J Neurochem (2001) 0.99

Mechanistic studies of early pausing events during initiation of HIV-1 reverse transcription. J Biol Chem (1998) 0.98

Clinicopathologic significance of urokinase receptor- and MMP-9-positive stromal cells in human colorectal cancer: functional multiplicity of matrix degradation on hematogenous metastasis. Int J Cancer (2000) 0.97

Effect of antacid on absorption of the quinolone lomefloxacin. Antimicrob Agents Chemother (1992) 0.96

Reconstitution of chromatin. The sequential binding of histones to DNA in the presence of salt and urea. J Mol Biol (1972) 0.96

The pincers effect on cervical spinal cord in the development of traumatic cervical spinal cord injury without major fracture or dislocation. Spinal Cord (2012) 0.96

A eubacterial Mycobacterium tuberculosis tRNA synthetase is eukaryote-like and resistant to a eubacterial-specific antisynthetase drug. Biochemistry (1996) 0.96

Efficient aminoacylation of tRNA(Lys,3) by human lysyl-tRNA synthetase is dependent on covalent continuity between the acceptor stem and the anticodon domain. Nucleic Acids Res (1999) 0.95

Chemical modification and site-directed mutagenesis of the single cysteine in motif 3 of class II Escherichia coli prolyl-tRNA synthetase. Biochemistry (1997) 0.95

Strong selective pressure to use G:U to mark an RNA acceptor stem for alanine. Biochemistry (1998) 0.94

Binding of actinomycin D to calf thymus chromatin. J Mol Biol (1971) 0.94

Transfer RNA aminoacylation: identification of a critical ribose 2'-hydroxyl-base interaction. RNA (1995) 0.94

Reverse transcriptase is an important factor for the primer tRNA selection in HIV-1. Leukemia (1994) 0.93

Operational RNA code for amino acids: species-specific aminoacylation of minihelices switched by a single nucleotide. Proc Natl Acad Sci U S A (1995) 0.92

Use of terbium as a probe of tRNA tertiary structure and folding. RNA (2000) 0.92

Increase in the accumulation of globin mRNA in immature erythroblasts in response to erythropoietin in vivo or in vitro. Exp Cell Res (1975) 0.92

Importance of discriminator base stacking interactions: molecular dynamics analysis of A73 microhelix(Ala) variants. Nucleic Acids Res (2000) 0.91

Identification of discriminator base atomic groups that modulate the alanine aminoacylation reaction. J Biol Chem (1999) 0.91

Pharmacological and functional characterization of muscarinic receptor subtypes in developing oligodendrocytes. J Neurochem (2001) 0.91

Aminoacyl-tRNA synthetases in biology and disease: new evidence for structural and functional diversity in an ancient family of enzymes. RNA (1997) 0.90

An elongation factor-associating domain is inserted into human cysteinyl-tRNA synthetase by alternative splicing. Nucleic Acids Res (2000) 0.90

Isolation and fractionation of retroviral tRNAs. J Virol Methods (1992) 0.89