Increase of gap junctions between pancreatic B-cells during stimulation of insulin secretion.

PubWeight™: 1.21‹?› | Rank: Top 10%

🔗 View Article (PMC 2110458)

Published in J Cell Biol on August 01, 1979

Authors

P Meda, A Perrelet, L Orci

Articles citing this

Emergence of organized bursting in clusters of pancreatic beta-cells by channel sharing. Biophys J (1988) 2.03

Gap junctions in several tissues share antigenic determinants with liver gap junctions. EMBO J (1984) 1.86

Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells. Biophys J (1991) 1.71

Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans. J Physiol (2014) 1.45

Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics. J Physiol (1998) 1.19

Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression. Hum Mol Genet (2008) 1.12

Connexins protect mouse pancreatic β cells against apoptosis. J Clin Invest (2011) 1.08

Adequate connexin-mediated coupling is required for proper insulin production. J Cell Biol (1995) 1.02

Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells. J Clin Invest (1990) 1.00

Direct communication of homologous and heterologous endocrine islet cells in culture. J Cell Biol (1982) 0.98

Minireview: intraislet regulation of insulin secretion in humans. Mol Endocrinol (2013) 0.92

In vitro, rapid assembly of gap junctions is induced by cytoskeleton disruptors. J Cell Biol (1983) 0.92

Three roads to islet bursting: emergent oscillations in coupled phantom bursters. Biophys J (2004) 0.91

Morphological changes of isolated rat pancreatic islets: a structural, ultrastructural and morphometric study. J Anat (2006) 0.88

Protein-mediated interactions of pancreatic islet cells. Scientifica (Cairo) (2013) 0.85

New insights into the role of connexins in pancreatic islet function and diabetes. FEBS Lett (2014) 0.84

Impact of islet architecture on β-cell heterogeneity, plasticity and function. Nat Rev Endocrinol (2016) 0.84

Intrinsic islet heterogeneity and gap junction coupling determine spatiotemporal Ca²⁺ wave dynamics. Biophys J (2014) 0.82

The intercellular synchronization of Ca2+ oscillations evaluates Cx36-dependent coupling. PLoS One (2012) 0.82

Upregulation of the expression of tight and adherens junction-associated proteins during maturation of neonatal pancreatic islets in vitro. J Mol Histol (2004) 0.78

A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells. PLoS One (2016) 0.76

Glibenclamide Prevents Diabetes in NOD Mice. PLoS One (2016) 0.75

Articles cited by this

Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes (1967) 11.63

Membrane ultrastructure at mammalian intercellular junctions. Prog Biophys Mol Biol (1973) 4.30

Functional subdivision of islets of Langerhans and possible role of D cells. Lancet (1975) 2.83

Gap junctions between electrotonically coupled cells in tissue culture and in brown fat. Proc Natl Acad Sci U S A (1971) 2.59

Inhibition of insulin secretion by somatostatin. Lancet (1973) 2.58

Gap junction formation between reaggregated Novikoff hepatoma cells. Proc Natl Acad Sci U S A (1974) 2.30

Gap junctions between photoreceptor cells in the vertebrate retina. Proc Natl Acad Sci U S A (1973) 2.19

Somatostatin: hypothalamic inhibitor of the endocrine pancreas. Science (1974) 2.11

Transmission of hormonal stimulation by cell-to-cell communication. Nature (1978) 2.08

Assembly of gap junctions during amphibian neurulation. J Cell Biol (1974) 1.88

Electrophysiological evidence for coupling between beta cells of pancreatic islets. Nature (1976) 1.86

Gap junctions. Structural changes after uncoupling procedures. J Cell Biol (1977) 1.82

A portrait of the pancreatic B-cell. The Minkowski Award Lecture delivered on July 19, 1973, during the 8th Congress of the International Diabetes Federation, held in Brussels, Belgium. Diabetologia (1974) 1.55

In vivo assembly of tight junctions in fetal rat liver. J Cell Biol (1975) 1.53

Structural coupling between pancreatic islet cells. Experientia (1973) 1.37

Gap junctions: their presence and necessity in myometrium during parturition. Science (1977) 1.35

Development of junctions during differentiation of lens fibers. Proc Natl Acad Sci U S A (1974) 1.32

Pronase effect on pancreatic beta cell secretion and morphology. Science (1973) 1.31

A morphological basis for intercellular communication between alpha- and beta-cells in the endocrine pancreas. J Clin Invest (1975) 1.23

Insulin secretion by isolated islets in presence of glucose, insulin and anti-insulin serum. Proc Soc Exp Biol Med (1967) 1.21

[Ultrastructural events associated with the action of tolbutamide and glybenclamide on pancreatic B-cells in vivo and in vitro]. Acta Diabetol Lat (1969) 1.17

Ovulation and the mechanism of follicle rupture. IV. Ultrastructure of membrana granulosa of rabbit graafian follicles prior to induced ovulation. Cell Tissue Res (1974) 1.13

Hormonal regulation of gap junction differentiation. J Cell Biol (1976) 1.09

Quantitative analysis of low-resistance junctions between cultured cells and correlation with gap-junctional areas. J Cell Biol (1978) 1.07

An intercellular response to estrogen by granulosa cells in the rat ovary; an electron microscope study. Endocrinology (1972) 1.05

The microanatomy of the islets of Langerhans. Metabolism (1976) 1.02

Intercellular communication in insect development is hormonally controlled. Science (1978) 1.01

Intraislet negative insulin-glucagon feedback. Metabolism (1976) 0.99

Intercellular junctions of oral epithelium. II. Ultrastructural changes in rat buccal epithelium induced by trypsin digestion. J Ultrastruct Res (1977) 0.96

Cell contacts in human islets of Langerhans. J Clin Endocrinol Metab (1975) 0.86

Stimulation of pancreatic immunoreactive somatostatin (IRS) release by glucagon [proceedings]. Metabolism (1976) 0.86

Electrophysiological evidence for the autoregulation of beta-cell secretion by insulin. Biochim Biophys Acta (1977) 0.83

Glucagon release from rat pancreatic islets. A combined morphological and functional approach. J Clin Invest (1977) 0.79

Articles by these authors

COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell (1994) 10.01

Molecular dissection of the secretory pathway. Nature (1992) 7.38

Ultrastructural localization of intracellular antigens by the use of protein A-gold complex. J Histochem Cytochem (1978) 7.15

Coat proteins and vesicle budding. Science (1996) 7.00

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell (1991) 6.30

Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci U S A (2000) 5.65

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology (1992) 5.45

Involvement of GTP-binding "G" proteins in transport through the Golgi stack. Cell (1987) 5.28

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell (1991) 4.98

ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell (1991) 4.80

COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell (1998) 4.73

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J (2001) 4.70

Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack. Cell (1989) 4.65

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack. Cell (1988) 4.37

Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins. Nature (1982) 4.22

Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell (1991) 4.17

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin. Nature (1991) 4.09

A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell (1986) 4.04

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci U S A (1978) 4.03

Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci U S A (1986) 3.42

Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. Proc Natl Acad Sci U S A (1987) 3.33

Bidirectional transport by distinct populations of COPI-coated vesicles. Cell (1997) 3.24

Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. J Biol Chem (1993) 3.01

In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices. J Cell Biol (1983) 2.91

COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell (1995) 2.87

New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes (1982) 2.87

Functional subdivision of islets of Langerhans and possible role of D cells. Lancet (1975) 2.83

Stepwise assembly of functionally active transport vesicles. Cell (1993) 2.80

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell (1991) 2.78

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell (1990) 2.77

Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. J Cell Biol (1994) 2.75

Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70

Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing. Proc Natl Acad Sci U S A (1988) 2.69

Direct identification of prohormone conversion site in insulin-secreting cells. Cell (1985) 2.64

Pancreatic beta-cell web: its possible role in insulin secretion. Science (1972) 2.63

Tumor-promoting phorbol esters induce angiogenesis in vitro. Cell (1985) 2.58

Studies of the diabetogenic action of streptozotocin. Proc Soc Exp Biol Med (1967) 2.55

The essential role of glucagon in the pathogenesis of diabetes mellitus. Lancet (1975) 2.54

Insulin within islets is a physiologic glucagon release inhibitor. J Clin Invest (1984) 2.52

Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles. J Cell Biol (1993) 2.51

Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun (1992) 2.47

125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography. J Clin Invest (1978) 2.47

Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus. Proc Natl Acad Sci U S A (1981) 2.45

Dynamics of the COPII coat with GTP and stable analogues. Nat Cell Biol (2001) 2.44

Macro- and micro-domains in the endocrine pancreas. Diabetes (1982) 2.43

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. Proc Natl Acad Sci U S A (1997) 2.42

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. J Cell Biol (1990) 2.36

A view of acidic intracellular compartments. J Cell Biol (1988) 2.35

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles. Cell (1987) 2.33

Regulation of fatty acid homeostasis in cells: novel role of leptin. Proc Natl Acad Sci U S A (1999) 2.33

The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. J Biol Chem (1992) 2.31

Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development (1991) 2.28

Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. Proc Natl Acad Sci U S A (1991) 2.27

Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun (1991) 2.25

Alpha-smooth muscle actin, a differentiation marker of smooth muscle cells, is present in microfilamentous bundles of pericytes. J Histochem Cytochem (1989) 2.23

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J Biol Chem (1986) 2.22

Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins. Nature (1993) 2.21

A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding. J Cell Biol (1996) 2.20

Occurrence of low density lipoprotein receptors within large pits on the surface of human fibroblasts as demonstrated by freeze-etching. Exp Cell Res (1978) 2.15

Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes. Proc Natl Acad Sci U S A (1998) 2.15

A role for the microtubular system in the release of very low density lipoproteins by perfused mouse livers. J Biol Chem (1973) 2.13

Unique and shared functions of different connexins in mice. Curr Biol (2000) 2.10

Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles. J Cell Biol (1986) 2.06

The trans-most cisternae of the Golgi complex: a compartment for sorting of secretory and plasma membrane proteins. Cell (1987) 2.00

Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro. J Cell Biol (1990) 2.00

A clathrin-coated, Golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin. Cell (1984) 1.99

Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. J Cell Sci (1995) 1.98

Quantitation of endocrine cell content in the pancreas of nondiabetic and diabetic humans. Diabetes (1982) 1.94

The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins). Endocr Rev (1982) 1.92

Connexin40 regulates renin production and blood pressure. Kidney Int (2007) 1.91

Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts. J Cell Biol (1982) 1.88

Somatostatinoma syndrome. Biochemical, morphologic and clinical features. N Engl J Med (1979) 1.88

Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol (2000) 1.87

Ultrastructural analysis of crystalloid endoplasmic reticulum in UT-1 cells and its disappearance in response to cholesterol. J Cell Sci (1983) 1.87

Underexpression of beta cell high Km glucose transporters in noninsulin-dependent diabetes. Science (1990) 1.85

Movement of proteins through the Golgi stack: a molecular dissection of vesicular transport. FASEB J (1990) 1.83

Fatty acyl-coenzyme A is required for budding of transport vesicles from Golgi cisternae. Cell (1989) 1.81

Heterogeneity and contact-dependent regulation of hormone secretion by individual B cells. Exp Cell Res (1986) 1.80

Quantitative immunocytochemical localization of pancreatic secretory proteins in subcellular compartments of the rat acinar cell. J Histochem Cytochem (1980) 1.80

Stimulation of insulin secretion reveals heterogeneity of pancreatic B cells in vivo. J Clin Invest (1987) 1.80

Physiology and pathophysiology of glucagon. Physiol Rev (1976) 1.79

Phalloidin-induced hyperplasia of actin filaments in rat hepatocytes. Lab Invest (1975) 1.78

Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J (2001) 1.72

Glucagon: role in the hyperglycemia of diabetes mellitus. Science (1975) 1.72

Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin. Diabetes (2000) 1.71

Megavesicles implicated in the rapid transport of intracisternal aggregates across the Golgi stack. Cell (2000) 1.70

A v-SNARE implicated in intra-Golgi transport. J Cell Biol (1996) 1.70