Somatostatinoma syndrome. Biochemical, morphologic and clinical features.

PubWeight™: 1.88‹?› | Rank: Top 3%

🔗 View Article (PMID 377080)

Published in N Engl J Med on August 09, 1979

Authors

G J Krejs, L Orci, J M Conlon, M Ravazzola, G R Davis, P Raskin, S M Collins, D M McCarthy, D Baetens, A Rubenstein, T A Aldor, R H Unger

Articles citing this

Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. Gastroenterology (2008) 3.04

Human somatostatin I: sequence of the cDNA. Proc Natl Acad Sci U S A (1982) 1.81

Site-specific biology and pathology of gastroenteropancreatic neuroendocrine tumors. Virchows Arch (2007) 1.70

The pancreas as a single organ: the influence of the endocrine upon the exocrine part of the gland. Gut (1981) 1.36

Insulinoma: pathophysiology, localization and management. Future Oncol (2010) 1.21

Identification of prosomatostatin in pancreatic islets. Proc Natl Acad Sci U S A (1980) 1.06

Multiple endocrine neoplasia associated with von Recklinghausen's disease. Br Med J (Clin Res Ed) (1983) 1.02

Effect of octreotide on gall stone prevalence and gall bladder motility in acromegaly. Gut (1993) 0.95

Postprandial gall bladder motility and hormone release during intermittent and continuous subcutaneous octreotide treatment in acromegaly. Gut (1993) 0.94

Gall-bladder water and electrolyte transport and its regulation. Gut (1983) 0.93

Correlation between gall bladder fasting volume and postprandial emptying in patients with gall stones and healthy controls. Gut (1993) 0.91

Duodenal somatostatinoma: a case report and review. Korean J Intern Med (2011) 0.88

Neurofibromatosis, phaeochromocytoma, and somatostatinoma. Br Med J (Clin Res Ed) (1982) 0.87

Pancreatic polypeptide-secreting islet-cell tumors. A study of three cases. Am J Pathol (1983) 0.86

Glandular duodenal carcinoid--a somatostatin rich tumour with neuroendocrine associations. J Clin Pathol (1984) 0.85

A mixed endocrine adrenal tumour causing steatorrhoea. Gut (1987) 0.84

Clearance of immunoreactive somatostatin by perfused rat liver. J Clin Invest (1981) 0.84

Characterization of three peptides derived from prosomatostatin [prosomatostatin-(1-63)-, -(65-76)- and -(79-92)-peptides] in a human pancreatic tumour. Biochem J (1987) 0.84

Rare and unusual endocrine cancer syndromes with mutated genes. Semin Oncol (2010) 0.84

Mixed pancreatic apudoma with symptoms of excess vasoactive intestinal polypeptide and insulin: improvement of diarrhoea with metoclopramide. Gut (1981) 0.82

Immunohistochemical study of pheochromocytomas. An investigation of methionine-enkephalin, vasoactive intestinal peptide, somatostatin, corticotropin, beta-endorphin, and calcitonin in 16 tumors. Am J Pathol (1984) 0.82

Duodenal somatostatinoma: a case report and review of the literature. J Med Case Rep (2013) 0.81

Important of case-reports/series, in rare diseases: Using neuroendocrine tumors as an example. World J Clin Cases (2014) 0.81

[Tumors of the endocrine pancreas]. Pathologe (2005) 0.80

Recent advances in pancreatic hormone research. Postgrad Med J (1983) 0.80

Shrinkage of thyrotrophin secreting pituitary adenoma treated with octreotide. Postgrad Med J (1991) 0.79

Asymptomatic somatostatinoma of the pancreatic head: Report of a case. Surg Today (2010) 0.79

Functioning gangliocytic paraganglioma of the ampulla: clinicopathological correlations and cytologic features. J Gastrointest Oncol (2016) 0.78

Co-secretion of calcitonin gene-related peptide, gastrin-releasing peptide and ACTH by a carcinoid tumour metastasizing to the cerebellum. Postgrad Med J (1987) 0.78

Incidental small ampullary somatostatinoma treated with ampullectomy 2 years after diagnosis. Dig Dis Sci (2006) 0.77

[Tumors of the endocrine pancreas]. Pathologe (2003) 0.77

Calcitonin-producing pancreatic somatostatinoma: report of a case. Surg Today (1998) 0.76

Morphological and functional investigations of neuroendocrine tumors of the pancreas. Eur Radiol (2003) 0.75

Metastatic Psammomatous Somatostatinoma of the Pancreas Causing Severe Ketoacidotic Diabetes Cured by Surgery. Endocr Pathol (1997) 0.75

Occult retroperitoneal carcinoid tumor with flushing and solitary lung metastasis. West J Med (1989) 0.75

Somatostatinoma--the most recently described pancreatic islet cell tumor. West J Med (1985) 0.75

Somatostatin-secreting Pheochromocytoma Mimicking Insulin-dependent Diabetes Mellitus. Intern Med (2016) 0.75

Effect of octreotide on human sphincter of Oddi motility following liver transplantation. Dig Dis Sci (1997) 0.75

Articles by these authors

COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell (1994) 10.01

The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2. JAMA (1997) 8.30

Molecular dissection of the secretory pathway. Nature (1992) 7.38

Ultrastructural localization of intracellular antigens by the use of protein A-gold complex. J Histochem Cytochem (1978) 7.15

Coat proteins and vesicle budding. Science (1996) 7.00

Mission critical--integrating clinician-educators into academic medical centers. N Engl J Med (1999) 6.41

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell (1991) 6.30

Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci U S A (2000) 5.65

Involvement of GTP-binding "G" proteins in transport through the Golgi stack. Cell (1987) 5.28

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell (1991) 4.98

ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell (1991) 4.80

Studies of pancreatic alpha cell function in normal and diabetic subjects. J Clin Invest (1970) 4.74

COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell (1998) 4.73

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci U S A (1998) 4.72

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J (2001) 4.70

Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack. Cell (1989) 4.65

The role of psychological and biological factors in postinfective gut dysfunction. Gut (1999) 4.54

The spc ribosomal protein operon of Escherichia coli: sequence and cotranscription of the ribosomal protein genes and a protein export gene. Nucleic Acids Res (1983) 4.46

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack. Cell (1988) 4.37

Psychometric scores and persistence of irritable bowel after infectious diarrhoea. Lancet (1996) 4.23

Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins. Nature (1982) 4.22

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin. Nature (1991) 4.09

A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell (1986) 4.04

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci U S A (1978) 4.03

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci U S A (1994) 4.01

Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res (2000) 3.74

Effect of troglitazone in insulin-treated patients with type II diabetes mellitus. Troglitazone and Exogenous Insulin Study Group. N Engl J Med (1998) 3.74

Cryptosporidiosis in immunocompetent patients. N Engl J Med (1985) 3.62

Transcription-based amplification system and detection of amplified human immunodeficiency virus type 1 with a bead-based sandwich hybridization format. Proc Natl Acad Sci U S A (1989) 3.56

Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci U S A (1986) 3.42

Pancreatic glucagon secretion in normal and diabetic subjects. Am J Med Sci (1969) 3.42

Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. Proc Natl Acad Sci U S A (1987) 3.33

Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion. N Engl J Med (1970) 3.27

Bidirectional transport by distinct populations of COPI-coated vesicles. Cell (1997) 3.24

HLA-DQ and T-cell receptor genes in insulin-dependent diabetes mellitus. Cold Spring Harb Symp Quant Biol (1986) 3.15

Direct antidiabetic effect of leptin through triglyceride depletion of tissues. Proc Natl Acad Sci U S A (1997) 3.07

Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. J Biol Chem (1993) 3.01

In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices. J Cell Biol (1983) 2.91

Development of a lavage solution associated with minimal water and electrolyte absorption or secretion. Gastroenterology (1980) 2.89

Interstitial pneumonia due to cytomegalovirus following low-dose methotrexate treatment for rheumatoid arthritis. Arthritis Rheum (1995) 2.88

COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell (1995) 2.87

New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes (1982) 2.87

Functional subdivision of islets of Langerhans and possible role of D cells. Lancet (1975) 2.83

Stepwise assembly of functionally active transport vesicles. Cell (1993) 2.80

DNA sequence of the promoter region for the alpha ribosomal protein operon in Escherichia coli. J Biol Chem (1980) 2.80

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell (1991) 2.78

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell (1990) 2.77

Mechanisms and management of antibiotic-associated diarrhea. Clin Infect Dis (1998) 2.75

Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. J Cell Biol (1994) 2.75

Self-reported drinking and alcohol-related problems among early adolescents: dimensionality and validity over 24 months. J Stud Alcohol (1995) 2.74

Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70

Chronic diarrhea of unknown origin. Gastroenterology (1980) 2.69

Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing. Proc Natl Acad Sci U S A (1988) 2.69

Evaluation of HbA1c determination methods in patients with hemoglobinopathies. Diabetes Care (2000) 2.65

On the sins of short-form development. Psychol Assess (2000) 2.65

Direct identification of prohormone conversion site in insulin-secreting cells. Cell (1985) 2.64

Pancreatic beta-cell web: its possible role in insulin secretion. Science (1972) 2.63

Studies of muscle capillary basement membranes in normal subjects, diabetic, and prediabetic patients. J Clin Invest (1968) 2.60

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression. J Biol Chem (1998) 2.59

Tumor-promoting phorbol esters induce angiogenesis in vitro. Cell (1985) 2.58

Glucagon levels and metabolic effects in fasting man. J Clin Invest (1970) 2.58

Studies of the diabetogenic action of streptozotocin. Proc Soc Exp Biol Med (1967) 2.55

The essential role of glucagon in the pathogenesis of diabetes mellitus. Lancet (1975) 2.54

The effects of secretin, pancreozymin, and gastrin on insulin and glucagon secretion in anesthetized dogs. J Clin Invest (1967) 2.53

Insulin within islets is a physiologic glucagon release inhibitor. J Clin Invest (1984) 2.52

Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles. J Cell Biol (1993) 2.51

Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. Cell (1999) 2.49

Haemoglobin A1: An indicator of the metabolic control of diabetic patients. Lancet (1977) 2.48

Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes. Diabetologia (1985) 2.48

Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun (1992) 2.47

125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography. J Clin Invest (1978) 2.47

Characterization of the responses of circulating glucagon-like immunoreactivity to intraduodenal and intravenous administration of glucose. J Clin Invest (1968) 2.46

Role of nitric oxide in obesity-induced beta cell disease. J Clin Invest (1997) 2.45

Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus. Proc Natl Acad Sci U S A (1981) 2.45

Dynamics of the COPII coat with GTP and stable analogues. Nat Cell Biol (2001) 2.44

Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. J Biol Chem (1995) 2.43

Macro- and micro-domains in the endocrine pancreas. Diabetes (1982) 2.43

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. Proc Natl Acad Sci U S A (1997) 2.42

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. J Cell Biol (1990) 2.36

A view of acidic intracellular compartments. J Cell Biol (1988) 2.35

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles. Cell (1987) 2.33

Regulation of fatty acid homeostasis in cells: novel role of leptin. Proc Natl Acad Sci U S A (1999) 2.33

The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. J Biol Chem (1992) 2.31

Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development (1991) 2.28

Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. Proc Natl Acad Sci U S A (1991) 2.27

Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun (1991) 2.25