R M Lechan

Author PubWeight™ 71.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 2001 4.34
2 Clinical problem-solving. Diverted by the chief complaint. N Engl J Med 1995 3.95
3 In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes. Histochem J 1987 2.04
4 Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology 1997 1.64
5 Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus. Science 1987 1.50
6 Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone. Endocrinology 1995 1.45
7 Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone. Endocrinology 1997 1.41
8 alpha-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression. J Neurosci 2000 1.41
9 Thyrotropin-releasing hormone precursor: characterization in rat brain. Science 1986 1.20
10 Regional expression of the type 3 iodothyronine deiodinase messenger ribonucleic acid in the rat central nervous system and its regulation by thyroid hormone. Endocrinology 1999 1.16
11 Calcium-sensing receptor in the rat hippocampus: a developmental study. Brain Res Dev Brain Res 1997 1.14
12 Neuropeptide Y has a central inhibitory action on the hypothalamic-pituitary-thyroid axis. Endocrinology 2001 1.11
13 Arcuate nucleus ablation prevents fasting-induced suppression of ProTRH mRNA in the hypothalamic paraventricular nucleus. Neuroendocrinology 1998 1.07
14 Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. J Neurosci 2000 1.06
15 Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat. Neurosci Lett 1998 1.05
16 Immunohistochemical localization of thyrotropin-releasing hormone in the rat hypothalamus and pituitary. Endocrinology 1982 1.05
17 Acrolein: a fixative for immunocytochemical localization of peptides in the central nervous system. J Histochem Cytochem 1983 1.00
18 Regional physiological adaptation of the central nervous system deiodinases to iodine deficiency. Am J Physiol Endocrinol Metab 2001 0.99
19 Thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is dependent upon feedback regulation by both triiodothyronine and thyroxine. Endocrinology 1992 0.99
20 Hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in the human hypothalamus are innervated by neuropeptide Y, agouti-related protein, and alpha-melanocyte-stimulating hormone. J Clin Endocrinol Metab 2000 0.96
21 Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide. Endocrinology 1990 0.96
22 Agouti-related protein containing nerve terminals innervate thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology 1999 0.96
23 Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1. Endocrinology 1993 0.94
24 Composite pheochromocytoma/ganglioneuroma of the adrenal gland associated with multiple endocrine neoplasia 2A: case report with immunohistochemical analysis. Am J Surg Pathol 1997 0.94
25 Triiodothyronine exerts direct cell-specific regulation of thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus. Endocrinology 1988 0.93
26 Localization of thyrotropin-releasing hormone prohormone messenger ribonucleic acid in rat brain in situ hybridization. Endocrinology 1987 0.90
27 Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland. Endocrinology 1995 0.90
28 The arcuate nucleus is the major source for neuropeptide Y-innervation of thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology 1998 0.90
29 Expression of thyroid hormone receptor beta 2 in rat hypothalamus. Endocrinology 1992 0.89
30 Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice. Science 1986 0.87
31 Suppression of thyrotropin-releasing hormone gene expression by interleukin-1-beta in the rat: implications for nonthyroidal illness. Neuroendocrinology 1994 0.86
32 Neuropeptide-Y-immunoreactive innervation of thyrotropin-releasing hormone-synthesizing neurons in the rat hypothalamic paraventricular nucleus. Endocrinology 1990 0.85
33 Prosomatostatin-specific antigen in rat brain: localization by immunocytochemical staining with an antiserum to a synthetic sequence of preprosomatostatin. Proc Natl Acad Sci U S A 1983 0.85
34 Immunolocalization of the thyrotropin-releasing hormone prohormone in the rat central nervous system. Endocrinology 1986 0.84
35 The hypothalamic 'tuberoinfundibular' system of the rat as demonstrated by horseradish peroxidase (HRP) microiontophoresis. Brain Res 1980 0.83
36 Association between pituitary adenylate cyclase-activating polypeptide and thyrotropin-releasing hormone in the rat hypothalamus. J Chem Neuroanat 1997 0.83
37 New paradigms in neuroendocrinology: relationships between obesity, systemic inflammation and the neuroendocrine system. J Endocrinol Invest 2004 0.83
38 Regulation of cocaine- and amphetamine-regulated transcript-synthesising neurons of the hypothalamic paraventricular nucleus by endotoxin; implications for lipopolysaccharide-induced regulation of energy homeostasis. J Neuroendocrinol 2008 0.82
39 alpha-Melanocyte stimulating hormone prevents fasting-induced suppression of corticotropin-releasing hormone gene expression in the rat hypothalamic paraventricular nucleus. Neurosci Lett 2000 0.82
40 The tuberoinfundibular system of the rat as demonstrated by immunohistochemical localization of retrogradely transported wheat germ agglutinin (WGA) from the median eminence. Brain Res 1982 0.82
41 Interleukin-6 (IL-6) is secreted from the brain after intracerebroventricular injection of IL-1 beta in rats. Am J Physiol 1996 0.82
42 Glucocorticoids inhibit stress-induced phosphorylation of CREB in corticotropin-releasing hormone neurons of the hypothalamic paraventricular nucleus. Neuroendocrinology 1997 0.81
43 Muscle denervation increases thyrotropin-releasing hormone (TRH) biosynthesis in the rat medullary raphe. Brain Res 1991 0.81
44 Isolated adrenocorticotropin deficiency associated with an autoantibody to a corticotroph antigen that is not adrenocorticotropin or other proopiomelanocortin-derived peptides. J Clin Endocrinol Metab 1990 0.81
45 Immunohistochemical identification of a novel substance with human growth hormone-like immunoreactivity in rat brain. Endocrinology 1981 0.80
46 Hypothalamic dorsomedial nucleus neurons innervate thyrotropin-releasing hormone-synthesizing neurons in the paraventricular nucleus. Brain Res 2001 0.80
47 Hypophysiotrophic thyrotropin releasing hormone (TRH) synthesizing neurons. Ultrastructure, adrenergic innervation and putative transmitter action. Histochemistry 1987 0.80
48 Immunohistochemical localization in the rat brain of the precursor for thyrotropin-releasing hormone. Science 1985 0.79
49 Neuroendocrine regulation of thyrotropin-releasing hormone (TRH) in the tuberoinfundibular system. J Endocrinol Invest 1993 0.79
50 Transient thyrotoxicosis and persistent hypothyroidism due to acute autoimmune thyroiditis after interleukin-2 and interferon-alpha therapy for metastatic carcinoma: a case report. Am J Med 1992 0.79
51 Ontogeny of thyrotropin-releasing hormone and histidyl proline diketopiperazine in the rat central nervous system and pancreas. Endocrinology 1984 0.79
52 The distribution of thyrotropin-releasing hormone (TRH) in the rhesus monkey spinal cord. Peptides 1984 0.78
53 Distribution of immunoreactive human growth hormone-like material and thyrotropin-releasing hormone in the rat central nervous system: evidence for their coexistence in the same neurons. Endocrinology 1983 0.78
54 Hypothalamic melanocortin signaling in cachexia. Endocrinology 2001 0.78
55 Hypothyroidism increases vasoactive intestinal polypeptide (VIP) immunoreactivity and gene expression in the rat hypothalamic paraventricular nucleus. Endocrinology 1992 0.77
56 Thyroid hormone regulates vasoactive intestinal peptide (VIP) mRNA levels in the rat anterior pituitary gland. Endocrinology 1989 0.77
57 DARPP-32 and CREB are present in type 2 iodothyronine deiodinase-producing tanycytes: implications for the regulation of type 2 deiodinase activity. Brain Res 2000 0.77
58 Amyotrophic lateral sclerosis: thyrotropin-releasing hormone and histidyl proline diketopiperazine in the spinal cord and cerebrospinal fluid. Neurology 1986 0.77
59 The syndrome of inappropriate antidiuretic hormone secretion associated with induction chemotherapy for squamous cell carcinoma of the head and neck. J Surg Oncol 1986 0.77
60 Thyrotropin-releasing-hormone-immunoreactive innervation of thyrotropin-releasing-hormone-tuberoinfundibular neurons in rat hypothalamus: anatomical basis to suggest ultrashort feedback regulation. Neuroendocrinology 1990 0.77
61 Effect of preproTRH antisense on thyrotropin-releasing hormone synthesis and viability of cultured rat diencephalic neurons. Endocrine 2001 0.77
62 Vasoactive intestinal peptide in the anterior pituitary is increased in hypothyroidism. Endocrinology 1989 0.76
63 Opiate withdrawal increases ProTRH gene expression in the ventrolateral column of the midbrain periaqueductal gray. Brain Res 1996 0.76
64 Effect of hypothyroidism on vasoactive intestinal polypeptide-immunoreactive neurons in forebrain-neurohypophysial nuclei of the rat brain. Brain Res 1995 0.76
65 Thyrotropin releasing hormone but not histidyl-proline diketopiperazine is depleted from rat spinal cord following 5,7-dihydroxytryptamine treatment. Brain Res 1985 0.76
66 Activation of anorexigenic pro-opiomelanocortin neurones during refeeding is independent of vagal and brainstem inputs. J Neuroendocrinol 2012 0.76
67 Synthesis of luteinising hormone releasing factor and thyrotropin-releasing factor in glutamate-lesioned mice. Nature 1976 0.76
68 Efferent projections of ProTRH neurons in the ventrolateral periaqueductal gray. Brain Res 2001 0.75
69 Evidence that spinal cord thyrotropin-releasing hormone is independent of the paraventricular nucleus. Neurosci Lett 1983 0.75
70 Identification and characterization of thyrotropin-releasing hormone precursor peptides in rat brain. Endocrinology 1987 0.75
71 Estrogen regulates the gene expression of vasoactive intestinal peptide in the anterior pituitary. Neuroendocrinology 1990 0.75
72 Multiple forms of human pancreatic growth hormone releasing factor-like immunoreactivity in teleost brain and pituitary. Endocrinology 1985 0.75
73 Gomori-positive astrocytes in primary culture: effects of in vitro age and cysteamine exposure. Brain Res Dev Brain Res 1990 0.75
74 Localization of somatostatin mRNA in the gut, pancreas and thyroid gland of the rat using antisense RNA probes for in situ hybridization. Acta Histochem Suppl 1987 0.75
75 Distribution of immunoreactive growth hormone releasing factor(1-44)NH2 in the tuberoinfundibular system of the rhesus monkey. Brain Res 1984 0.75
76 proTRH gene expression by fetal pancreatic islets in culture. Biochem Biophys Res Commun 1990 0.75
77 Neurons containing a N-terminal sequence of the TRH-prohormone (preproTRH53-74) are present in a unique location of the midbrain periaqueductal gray of the rat. Brain Res 1988 0.75
78 Endocrinology and art. Acromegaly and goiter in the Pre-Columbian, Mesoamerican population. J Endocrinol Invest 2007 0.75
79 Effect of spinal cord TRH deficiency on lower motorneuron function in the rat. Muscle Nerve 1987 0.75
80 Glial peroxidase activity in the hypothalamic arcuate nucleus: effects of estradiol valerate-induced persistent estrus. Brain Res 1990 0.75
81 Immunohistochemical localization of retrogradely and anterogradely transported wheat germ agglutinin (WGA) within the central nervous system of the rat: application to immunostaining of a second antigen within the same neuron. J Histochem Cytochem 1981 0.75
82 Goiter in the court of the Byzantine Empress, Theodora. J Endocrinol Invest 2005 0.75
83 1-naphthol-pyronin B as a novel substrate for silver intensification: application to light and electron microscopic immunocytochemistry of neuroendocrine systems. J Histochem Cytochem 1990 0.75
84 Immunoreactive neuronal pathways of growth hormone-releasing hormone (GRH) in the brain and pituitary of the teleost Gadus morhua. Cell Tissue Res 1985 0.75
85 Immunohistochemical localization of human growth hormone-like material in the median eminence of the rat: light and electron microscopic observations. Neurosci Lett 1982 0.75
86 Spinal cord TRH deficiency is associated with incomplete recovery of denervated muscle in the rat. Neurology 1988 0.75
87 Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1. Neuroendocrinology 1993 0.75
88 Paraventricular nucleus mediates prolactin secretory responses to restraint stress, ether stress, and 5-hydroxy-L-tryptophan injection in the rat. Endocrinology 1987 0.75