Published in Endocrinology on August 01, 1997
Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocr Rev (2008) 2.98
A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. Cell Metab (2007) 2.48
American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models. Thyroid (2013) 1.41
Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells. J Clin Invest (2010) 1.29
Hypothalamic tanycytes: potential roles in the control of feeding and energy balance. Trends Neurosci (2013) 1.26
Generation and characterization of dickkopf3 mutant mice. Mol Cell Biol (2006) 1.26
A riot of rhythms: neuronal and glial circadian oscillators in the mediobasal hypothalamus. Mol Brain (2009) 1.21
Negative feedback regulation of hypophysiotropic thyrotropin-releasing hormone (TRH) synthesizing neurons: role of neuronal afferents and type 2 deiodinase. Front Neuroendocrinol (2007) 1.14
The MCT8 thyroid hormone transporter and Allan-Herndon-Dudley syndrome. Best Pract Res Clin Endocrinol Metab (2007) 1.13
Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes. J Clin Invest (1998) 1.07
Minireview: cracking the metabolic code for thyroid hormone signaling. Endocrinology (2011) 1.04
Critical role of types 2 and 3 deiodinases in the negative regulation of gene expression by T₃in the mouse cerebral cortex. Endocrinology (2012) 1.04
Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine. J Clin Invest (2015) 1.03
Coordination of hypothalamic and pituitary T3 production regulates TSH expression. J Clin Invest (2013) 1.01
Minireview: The neural regulation of the hypothalamic-pituitary-thyroid axis. Endocrinology (2012) 0.99
The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo. Endocrinology (2009) 0.97
Tanycyte pyroglutamyl peptidase II contributes to regulation of the hypothalamic-pituitary-thyroid axis through glial-axonal associations in the median eminence. Endocrinology (2009) 0.97
Thyroid hormone signaling in energy homeostasis and energy metabolism. Ann N Y Acad Sci (2014) 0.92
Transcriptional regulation of mammalian selenoprotein expression. Biochim Biophys Acta (2009) 0.92
Inhibition of the type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment. Endocrinology (2010) 0.91
Thyroid hormone and seasonal rhythmicity. Front Endocrinol (Lausanne) (2014) 0.91
Central regulation of hypothalamic-pituitary-thyroid axis under physiological and pathophysiological conditions. Endocr Rev (2013) 0.90
Tissue-specific inactivation of type 2 deiodinase reveals multilevel control of fatty acid oxidation by thyroid hormone in the mouse. Diabetes (2014) 0.88
Thyroid hormone action: astrocyte-neuron communication. Front Endocrinol (Lausanne) (2014) 0.87
A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons. PLoS One (2012) 0.87
Timing of metamorphosis and the onset of the negative feedback loop between the thyroid gland and the pituitary is controlled by type II iodothyronine deiodinase in Xenopus laevis. Proc Natl Acad Sci U S A (2001) 0.87
Thyroid hormones and methylmercury toxicity. Biol Trace Elem Res (2008) 0.86
Induction of type 2 iodothyronine deiodinase in the mediobasal hypothalamus by bacterial lipopolysaccharide: role of corticosterone. Endocrinology (2008) 0.85
The ups and downs of thyrotropin-releasing hormone. Endocrinology (2009) 0.85
Thyroid hormone regulation by stress and behavioral differences in adult male rats. Horm Behav (2011) 0.84
Thyroid hormone and the neuroglia: both source and target. J Thyroid Res (2011) 0.84
The central effects of thyroid hormones on appetite. J Thyroid Res (2011) 0.83
Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase. J Endocrinol (2011) 0.83
Thyroid hormones, t3 and t4, in the brain. Front Endocrinol (Lausanne) (2014) 0.83
Scope and limitations of iodothyronine deiodinases in hypothyroidism. Nat Rev Endocrinol (2015) 0.82
Endocrine mechanisms of seasonal adaptation in small mammals: from early results to present understanding. J Comp Physiol B (2010) 0.82
The role and potential sites of action of thyroid hormone in timing the onset of puberty in male primates. Brain Res (2010) 0.81
Hypothalamic tanycytes-masters and servants of metabolic, neuroendocrine, and neurogenic functions. Front Neurosci (2015) 0.81
The role of the iodothyronine deiodinases in the physiology and pathophysiology of thyroid hormone action. Eur Thyroid J (2012) 0.80
The dilemma of the nonthyroidal illness syndrome. Acta Biomed (2008) 0.80
Physiological role and regulation of iodothyronine deiodinases: a 2011 update. J Endocrinol Invest (2011) 0.80
Contribution of TNF-alpha and nuclear factor-kappaB signaling to type 2 iodothyronine deiodinase activation in the mediobasal hypothalamus after lipopolysaccharide administration. Endocrinology (2010) 0.80
Abnormal motor phenotype at adult stages in mice lacking type 2 deiodinase. PLoS One (2014) 0.80
Inflammation-inducible type 2 deiodinase expression in the leptomeninges, choroid plexus, and at brain blood vessels in male rodents. Endocrinology (2014) 0.79
Maternal nutrient deprivation induces sex-specific changes in thyroid hormone receptor and deiodinase expression in the fetal guinea pig brain. J Physiol (2005) 0.78
Thyroid hormone and the developing hypothalamus. Front Neuroanat (2015) 0.78
Variable proopiomelanocortin expression in tanycytes of the adult rat hypothalamus and pituitary stalk. J Comp Neurol (2016) 0.75
Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals. Front Endocrinol (Lausanne) (2017) 0.75
Understanding the hypothalamus-pituitary-thyroid axis in mct8 deficiency. Eur Thyroid J (2012) 0.75
Maternal photoperiod programs hypothalamic thyroid status via the fetal pituitary gland. Proc Natl Acad Sci U S A (2017) 0.75
Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region. Nature (1991) 4.63
Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol (2001) 4.34
Clinical problem-solving. Diverted by the chief complaint. N Engl J Med (1995) 3.95
Biodegradable block copolymers as injectable drug-delivery systems. Nature (1997) 3.48
Positive serum antibody and negative tissue staining for Helicobacter pylori in subjects with atrophic body gastritis. Gastroenterology (1991) 3.38
Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons. EMBO J (1993) 3.14
Screening for congenital hypothyroidism: results of screening one million North American infants. J Pediatr (1979) 3.07
Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature (1991) 3.06
Levothyroxine therapy in patients with thyroid disease. Ann Intern Med (1993) 2.96
Relationships between circulating and intracellular thyroid hormones: physiological and clinical implications. Endocr Rev (1981) 2.78
The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J Clin Invest (2001) 2.77
Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature (1989) 2.46
Maternal and fetal thyroid function. N Engl J Med (1994) 2.43
Identification of a thyroid hormone receptor that is pituitary-specific. Science (1989) 2.37
Exon trapping: a genetic screen to identify candidate transcribed sequences in cloned mammalian genomic DNA. Proc Natl Acad Sci U S A (1990) 2.15
Thyroid-pituitary interaction: feedback regulation of thyrotropin secretion by thyroid hormones. N Engl J Med (1982) 2.12
In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes. Histochem J (1987) 2.04
Increased need for thyroxine during pregnancy in women with primary hypothyroidism. N Engl J Med (1990) 2.03
Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix. Neuron (2001) 2.01
Adrenergic activation of triiodothyronine production in brown adipose tissue. Nature (1983) 1.97
Usefulness of ultrasonography in the management of nodular thyroid disease. Ann Intern Med (2000) 1.88
Management of foreign bodies in the gastrointestinal tract: an analysis of 104 cases in children. Endoscopy (1999) 1.87
Direct immunoassay of triiodothyronine in human serum. J Clin Invest (1972) 1.87
Chemotherapeutic trial to control enterobiasis in schoolchildren. Korean J Parasitol (1997) 1.86
Substitution of cysteine for selenocysteine in type I iodothyronine deiodinase reduces the catalytic efficiency of the protein but enhances its translation. Endocrinology (1992) 1.80
Symptomatic duodenal diverticulum. World J Surg (1995) 1.78
Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria. Metab Eng (2000) 1.75
Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element. Mol Endocrinol (1989) 1.73
Serotonin transporter gene polymorphism and irritable bowel syndrome. Neurogastroenterol Motil (2006) 1.72
Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med (2000) 1.72
Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology (1997) 1.64
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest (1997) 1.63
Pituitary nuclear 3,5,3'-triiodothyronine and thyrotropin secretion: an explanation for the effect of thyroxine. Science (1977) 1.61
Efficacy and tolerability of initial combination therapy with vildagliptin and pioglitazone compared with component monotherapy in patients with type 2 diabetes. Diabetes Obes Metab (2007) 1.61
Overexpression of peroxiredoxin in human breast cancer. Anticancer Res (2001) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Crystal structures of the membrane-binding C2 domain of human coagulation factor V. Nature (1999) 1.58
An analysis of the sources and quantity of 3,5,3'-triiodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology (1982) 1.58
Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review. J Hosp Infect (2006) 1.57
Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth. Gastroenterology (1991) 1.57
Production of cellulases and hemicellulases by Aspergillus niger KK2 from lignocellulosic biomass. Bioresour Technol (2004) 1.56
Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase. J Biol Chem (1991) 1.55
Repression mediates cell-type-specific expression of the rat growth hormone gene. Proc Natl Acad Sci U S A (1986) 1.53
Effect of decreasing afferent vagal activity with ondansetron on symptoms of bulimia nervosa: a randomised, double-blind trial. Lancet (2000) 1.53
Seroepidemiological study of Helicobacter pylori infection in asymptomatic people in South Korea. J Gastroenterol Hepatol (2001) 1.53
Tissue-engineered growth of cartilage: the effect of varying the concentration of chondrocytes seeded onto synthetic polymer matrices. Int J Oral Maxillofac Surg (1994) 1.52
Electrically erodible polymer gel for controlled release of drugs. Nature (1991) 1.50
Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus. Science (1987) 1.50
Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers. J Control Release (2000) 1.49
The effect of diphenylhydantoin on thyroxine metabolism in man. J Clin Invest (1970) 1.47
The contribution of local tissue thyroxine monodeiodination to the nuclear 3,5,3'-triiodothyronine in pituitary, liver, and kidney of euthyroid rats. Endocrinology (1978) 1.46
Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor. Proc Natl Acad Sci U S A (1988) 1.46
Evidence for two tissue-specific pathways for in vivo thyroxine 5'-deiodination in the rat. J Clin Invest (1982) 1.46
Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor. New Biol (1989) 1.45
Neonatal thyroid function in congenital hypothyroidism. J Pediatr (1976) 1.45
Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone. Endocrinology (1995) 1.45
Prognostic impact of hyponatraemia in patients with colorectal cancer. Colorectal Dis (2015) 1.44
[Increased expression of hypoxia-inducible factor-1α and connective tissue growth factor accompanied by fibrosis in the rat testis of varicocele]. Actas Urol Esp (2012) 1.44
Prophylactic efficacy of a new gentamicin-releasing urethral catheter in short-term catheterized rabbits. BJU Int (2001) 1.44
Detection of five rare cystic fibrosis mutations peculiar to Southern Italy: implications in screening for the disease and phenotype characterization for patients with homozygote mutations. Clin Chem (1999) 1.44
One micrometer resolution NMR microscopy. J Magn Reson (2001) 1.44
Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism. Am J Physiol (1980) 1.43
Clinicopathologic features of the intraductal growth type of peripheral cholangiocarcinoma. Hepatology (2000) 1.43
MR imaging-histopathologic correlation of radiofrequency thermal ablation lesion in a rabbit liver model: observation during acute and chronic stages. Korean J Radiol (2001) 1.43
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder. Sleep (1992) 1.41
Extracorporeal circulation combined with hypothermia and hemodilution technique. Yonsei Med J (1963) 1.40
Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor. J Biol Chem (1989) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Thyroid hormone regulation of gene expression. Annu Rev Physiol (1991) 1.39
Development of thyroid papillary carcinomas secondary to tissue-specific expression of the RET/PTC1 oncogene in transgenic mice. Oncogene (1996) 1.39
Wedge resection and modified mattress suture for correcting anterior septal deviation: how we do it. Clin Otolaryngol (2011) 1.38
Triiodothyronine: review of recent studies of its physiology and pathophysiology in man. Metabolism (1972) 1.37
Clinicopathologic and genotypic study of extranodal nasal-type natural killer/T-cell lymphoma and natural killer precursor lymphoma among Koreans. Cancer (2000) 1.37
Plasma T4 and T3 levels in naturally metamorphosing Eurycea bislineata (Amphibia; Plethodontidae). Gen Comp Endocrinol (1986) 1.37
Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex. Proc Natl Acad Sci U S A (1982) 1.37
Screening for congenital hypothyroidism. Results in the newborn population of New England. JAMA (1978) 1.35
Selective proteolysis of human type 2 deiodinase: a novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation. Mol Endocrinol (2000) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Fluoroscopy-aided thoracoscopic resection of pulmonary nodule localized with contrast media. Ann Thorac Surg (1999) 1.34
Inhibition of intrapituitary thyroxine to 3.5.3'-triiodothyronine conversion prevents the acute suppression of thyrotropin release by thyroxine in hypothyroid rats. J Clin Invest (1979) 1.34
Potential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats. J Clin Invest (1985) 1.34
Molecular biological and biochemical characterization of the human type 2 selenodeiodinase. Endocrinology (1996) 1.33
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2. Blood (2000) 1.31
Technical aspects of the estimation of triiodothyronine in human serum: evidence of conversion of thyroxine to triiodothyronine during assay. Metabolism (1971) 1.31
Thyroid hormone receptor binds to a site in the rat growth hormone promoter required for induction by thyroid hormone. Proc Natl Acad Sci U S A (1987) 1.31
Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism. J Clin Invest (1983) 1.30
Cerebral cortex responds rapidly to thyroid hormones. Science (1981) 1.29
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Type 2 iodothyronin deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis. Endocrinology (2001) 1.27
Prevalence and clinical features of body dysmorphic disorder in adolescent and adult psychiatric inpatients. J Clin Psychiatry (2001) 1.27
Type 2 iodothyronine deiodinase is highly expressed in human thyroid. J Clin Invest (1996) 1.26