Published in N Engl J Med on August 07, 1975
Predictive value of the ear-crease sign in coronary artery disease. Can Med Assoc J (1982) 1.57
Lack of association of diagonal earlobe crease with other cardiovascular risk factors. West J Med (1984) 1.18
Diagonal earlobe creases, type A behavior and the death of Emperor Hadrian. West J Med (1980) 1.02
Diagonal ear lobe crease and atherosclerosis: a review of the medical literature and dental implications. Med Oral Patol Oral Cir Bucal (2012) 1.00
Diagonal earlobe creases and fatal cardiovascular disease: a necropsy study. Br Heart J (1989) 0.91
Predictive value of auricular diagnosis on coronary heart disease. Evid Based Complement Alternat Med (2012) 0.86
Earlobe crease and coronary heart disease in Japanese. Heart Vessels (1986) 0.85
Diagonal ear-lobe crease: an independent risk factor in coronary heart disease? Ulster Med J (1980) 0.78
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Diabetic nephropathy in Type 1 (insulin-dependent) diabetes: an epidemiological study. Diabetologia (1983) 4.48
Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy. Lancet (1983) 3.01
Early detection of patients at risk of developing diabetic nephropathy. A longitudinal study of urinary albumin excretion. Acta Endocrinol (Copenh) (1982) 2.75
Effect of antihypertensive treatment on kidney function in diabetic nephropathy. Br Med J (Clin Res Ed) (1987) 2.35
Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review. Growth Hormone Research Society Scientific Committee. J Clin Endocrinol Metab (1998) 1.89
Timing and topography of cerebral blood flow, aura, and headache during migraine attacks. Ann Neurol (1990) 1.87
Rapid changes in chromatographically determined haemoglobin A1c induced by short-term changes in glucose concentration. Diabetologia (1980) 1.71
Beneficial effects of growth hormone treatment in GH-deficient adults. Lancet (1989) 1.63
Hemodynamic factors in the genesis of diabetic microangiopathy. Metabolism (1983) 1.56
A prospective study of glomerular filtration rate and arterial blood pressure in insulin-dependent diabetics with diabetic nephropathy. Diabetologia (1981) 1.53
Increased kidney size, glomerular filtration rate and renal plasma flow in short-term insulin-dependent diabetics. Diabetologia (1981) 1.53
The comparison of venous plasma glucose and whole blood capillary glucose in diagnoses of Type 2 diabetes: a population-based screening study. Diabet Med (2005) 1.53
Dose-response effects of free fatty acids on amino acid metabolism and ureagenesis. Acta Physiol (Oxf) (2007) 1.52
Prevalence of diabetic autonomic neuropathy measured by simple bedside tests. Diabetologia (1981) 1.46
Diabetic nephropathy and arterial hypertension. Diabetologia (1983) 1.45
Circadian variation of blood pressure in patients with diabetic nephropathy. Diabetologia (1992) 1.42
Ischaemia-induced (symptomatic) migraine attacks may be more frequent than migraine-induced ischaemic insults. Brain (1993) 1.42
Growth hormone dose regimens in adult GH deficiency: effects on biochemical growth markers and metabolic parameters. Clin Endocrinol (Oxf) (1993) 1.40
Trends in symptoms of obstructive lung disease in Norway. Int J Tuberc Lung Dis (2004) 1.38
[Surgical treatment of epilepsy resistant to drug therapy. A review]. Ugeskr Laeger (1991) 1.38
Increased growth rate following transfer to daily sc administration from three weekly im injections of hGH in growth hormone deficient children. Acta Endocrinol (Copenh) (1983) 1.37
Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults. Am J Physiol (1997) 1.31
Fast glycosylation of haemoglobin. Lancet (1979) 1.28
Effect of intravenous glucose infusion on renal function in normal man and in insulin-dependent diabetics. Diabetologia (1981) 1.24
Reduced sweating in adults with growth hormone deficiency. Lancet (1989) 1.16
The retention of [99mTc]-d,l-HM-PAO in the human brain after intracarotid bolus injection: a kinetic analysis. J Cereb Blood Flow Metab (1988) 1.15
Renal function in streptozotocin-diabetic rats. Diabetologia (1981) 1.13
Effects of cortisol on lipolysis and regional interstitial glycerol levels in humans. Am J Physiol Endocrinol Metab (2002) 1.12
The impact of obesity, fat distribution, and energy restriction on insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, insulin, and growth hormone. Metabolism (1994) 1.12
Diabetic nephropathy and arterial hypertension. The effect of antihypertensive treatment. Diabetes (1983) 1.12
Autonomic and somatosensory nerve function after 2 years of continuous subcutaneous insulin infusion in type I diabetes. Diabetes (1988) 1.11
Paroxetine in the treatment of panic disorder. A randomised, double-blind, placebo-controlled study. Br J Psychiatry (1995) 1.10
Danish very-low-dose aspirin after carotid endarterectomy trial. Stroke (1988) 1.10
Impaired autoregulation of glomerular filtration rate in type 1 (insulin-dependent) diabetic patients with nephropathy. Diabetologia (1984) 1.07
Glucose metabolism, lipid metabolism, and cardiovascular risk factors in adult Turner's syndrome. The impact of sex hormone replacement. Diabetes Care (1998) 1.06
Detection of growth hormone abuse in sport. Growth Horm IGF Res (2007) 1.05
Kidney function and size in diabetics before and during initial insulin treatment. Kidney Int (1982) 1.05
Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure. Diabetes (2001) 1.05
Imitation of normal plasma growth hormone profile by subcutaneous administration of human growth hormone to growth hormone deficient children. Acta Endocrinol (Copenh) (1983) 1.05
Glucose monitoring by microdialysis: performance in a multicentre study. Diabet Med (2009) 1.04
Growth hormone administration by means of an injection pen. Pharmacol Toxicol (1989) 1.03
GH strongly affects serum concentrations of mannan-binding lectin: evidence for a new IGF-I independent immunomodulatory effect of GH. J Clin Endocrinol Metab (2001) 1.03
Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults. J Clin Endocrinol Metab (2011) 1.03
Fast glycosylation of hemoglobin. Lancet (1979) 1.03
Ghrelin receptor agonist (TZP-101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis. Aliment Pharmacol Ther (2009) 1.02
Synthesis of glycosylated haemoglobin in vivo. Diabetologia (1981) 1.02
Insulin analogues and severe hypoglycaemia in type 1 diabetes. Diabetes Res Clin Pract (2011) 1.01
Effects of a physiological GH pulse on interstitial glycerol in abdominal and femoral adipose tissue. Am J Physiol (1999) 1.01
Treatment of myofascial trigger-points with ultrasound combined with massage and exercise--a randomised controlled trial. Pain (1998) 1.01
Long-term effects of continuous subcutaneous infusion versus daily subcutaneous injections of growth hormone (GH) on the insulin-like growth factor system, insulin sensitivity, body composition, and bone and lipoprotein metabolism in GH-deficient adults. J Clin Endocrinol Metab (2001) 1.00
Growth and endocrinological disorders up to 21 years after treatment for acute lymphoblastic leukemia in childhood. Med Pediatr Oncol (1998) 1.00
Bone mineral density in Klinefelter syndrome is reduced and primarily determined by muscle strength and resorptive markers, but not directly by testosterone. Osteoporos Int (2010) 0.99
Responses of markers of bone and collagen turnover to exercise, growth hormone (GH) administration, and GH withdrawal in trained adult males. J Clin Endocrinol Metab (2000) 0.99
Effects of indomethacin on glomerular hemodynamics in experimental diabetes. Kidney Int (1986) 0.99
The effect of intravenous insulin infusion on kidney function in insulin-dependent diabetes mellitus. Diabetologia (1981) 0.99
Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients. Metabolism (2000) 0.99
Dose-response effects of free fatty acids on glucose and lipid metabolism during somatostatin blockade of growth hormone and insulin in humans. J Clin Endocrinol Metab (2007) 0.99
SPECT with [99mTc]-d,l-hexamethyl-propylene amine oxime (HM-PAO) compared with regional cerebral blood flow measured by PET: effects of linearization. J Cereb Blood Flow Metab (1988) 0.97
Insulin-like growth factor I stimulates lipid oxidation, reduces protein oxidation, and enhances insulin sensitivity in humans. J Clin Invest (1993) 0.97
Whole body and regional soft tissue changes in growth hormone deficient adults after one year of growth hormone treatment: a double-blind, randomized, placebo-controlled study. Clin Endocrinol (Oxf) (1995) 0.96
Pulsatile versus continuous intravenous administration of growth hormone (GH) in GH-deficient patients: effects on circulating insulin-like growth factor-I and metabolic indices. J Clin Endocrinol Metab (1990) 0.96
The effect of four weeks of supraphysiological growth hormone administration on the insulin-like growth factor axis in women and men. GH-2000 Study Group. J Clin Endocrinol Metab (2000) 0.96
Effects of growth hormone therapy on thyroid function of growth hormone-deficient adults with and without concomitant thyroxine-substituted central hypothyroidism. J Clin Endocrinol Metab (1989) 0.96
The effect of 30 months of low-dose replacement therapy with recombinant human growth hormone (rhGH) on insulin and C-peptide kinetics, insulin secretion, insulin sensitivity, glucose effectiveness, and body composition in GH-deficient adults. J Clin Endocrinol Metab (2000) 0.95
An evaluation of the relationship between adult height and health-related quality of life in the general UK population. Clin Endocrinol (Oxf) (2007) 0.95
Occupational capacity after hip replacement. Acta Orthop Scand (1985) 0.94
The ghrelin response to exercise before and after growth hormone administration. J Clin Endocrinol Metab (2006) 0.94
Abnormalities of whole body protein turnover, muscle metabolism and levels of metabolic hormones in patients with chronic heart failure. J Intern Med (2006) 0.93
Reduced regional cerebral blood flow in Huntington's disease studied by SPECT. J Neurol Neurosurg Psychiatry (1992) 0.93
Kidney function and size in normal subjects before and during growth hormone administration for one week. Eur J Clin Invest (1981) 0.93
The protein-retaining effects of growth hormone during fasting involve inhibition of muscle-protein breakdown. Diabetes (2001) 0.93
Adult growth hormone deficiency. Horm Res (1994) 0.93
Relation between diagnoses on severity, sick leave and loss of job among patients with occupational hand eczema. Br J Dermatol (2005) 0.93
99mTc-d,l-HMPAO and SPECT of the brain in normal aging. J Cereb Blood Flow Metab (1991) 0.93
Acute and long-term renal effects of angiotensin converting enzyme inhibition in normotensive, normoalbuminuric insulin-dependent diabetic patients. Diabet Med (1988) 0.92
Increased pulsatile, but not basal, growth hormone secretion rates and plasma insulin-like growth factor I levels during the periovulatory interval in normal women. J Clin Endocrinol Metab (1998) 0.92
Prognosis for juvenile diabetics with nephropathy and failing renal function. Acta Med Scand (1978) 0.92
Three different premixed combinations of biphasic insulin aspart - comparison of the efficacy and safety in a randomized controlled clinical trial in subjects with type 2 diabetes. Diabetes Obes Metab (2009) 0.92
Increased myocardial contractility following growth hormone administration in normal man. An echocardiographic study. Dan Med Bull (1988) 0.91
Effect on renal haemodynamics, glomerular filtration rate and albumin excretion of high oral protein load. Scand J Clin Lab Invest (1986) 0.91
The relationship between pregnancy, HCS and B lymphocytes. Acta Pathol Microbiol Scand C (1976) 0.90
Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: a double blind, randomized, placebo-controlled study. J Clin Endocrinol Metab (1996) 0.90
Subcutaneous degradation of insulin. Diabetologia (1981) 0.90
Functional and morphological renal manifestations in diabetes mellitus. Diabetologia (1981) 0.89
Retention of 99mTc-bicisate in the human brain after intracarotid injection. J Cereb Blood Flow Metab (1994) 0.89
Continuous infusion versus daily injections of growth hormone (GH) for 4 weeks in GH-deficient patients. J Clin Endocrinol Metab (1995) 0.88
B, T and null lymphocytes in newborn infants and their mothers. Acta Paediatr Scand (1976) 0.88
Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients. J Clin Endocrinol Metab (1995) 0.88
Effects of growth hormone on glucose metabolism. Horm Res (1991) 0.88
Continuation of growth hormone (GH) substitution during fasting in GH-deficient patients decreases urea excretion and conserves protein synthesis. J Clin Endocrinol Metab (2001) 0.88