Published in N Engl J Med on May 31, 2001
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Genet (2007) 6.83
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog (2013) 6.14
The immune response during acute HIV-1 infection: clues for vaccine development. Nat Rev Immunol (2009) 5.99
Impact of MHC class I diversity on immune control of immunodeficiency virus replication. Nat Rev Immunol (2008) 5.17
HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. PLoS Med (2006) 4.19
Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J Exp Med (2007) 4.14
Common genetic variation and the control of HIV-1 in humans. PLoS Genet (2009) 3.68
HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C. Nat Genet (2009) 3.03
Mamu-A*01 allele-mediated attenuation of disease progression in simian-human immunodeficiency virus infection. J Virol (2002) 2.44
Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1. J Virol (2002) 2.38
Acute HIV revisited: new opportunities for treatment and prevention. J Clin Invest (2004) 2.30
Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes. J Virol (2007) 2.26
Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies. Hum Immunol (2008) 2.22
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. J Virol (2004) 2.09
Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads. PLoS One (2008) 2.06
KIR/HLA pleiotropism: protection against both HIV and opportunistic infections. PLoS Pathog (2006) 2.06
Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression. J Virol (2007) 1.98
APOBEC3G genetic variants and their influence on the progression to AIDS. J Virol (2004) 1.97
Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS. Proc Natl Acad Sci U S A (2004) 1.97
HIV and HLA class I: an evolving relationship. Immunity (2012) 1.91
HLA-Cw*04 and hepatitis C virus persistence. J Virol (2002) 1.83
HLA alleles associated with slow progression to AIDS truly prefer to present HIV-1 p24. PLoS One (2007) 1.77
HLA/KIR restraint of HIV: surviving the fittest. Annu Rev Immunol (2011) 1.66
HIV-1 vaccine development after STEP. Annu Rev Med (2010) 1.64
Modulating influence on HIV/AIDS by interacting RANTES gene variants. Proc Natl Acad Sci U S A (2002) 1.61
HIV-1 continues to replicate and evolve in patients with natural control of HIV infection. J Virol (2010) 1.57
KIR-HLA intercourse in HIV disease. Trends Microbiol (2008) 1.55
Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes. PLoS One (2010) 1.49
Copy number variation of KIR genes influences HIV-1 control. PLoS Biol (2011) 1.44
Human immunodeficiency virus type 1-hepatitis C virus coinfection: intraindividual comparison of cellular immune responses against two persistent viruses. J Virol (2002) 1.40
Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype. J Virol (2010) 1.39
A novel single cDNA amplicon pyrosequencing method for high-throughput, cost-effective sequence-based HLA class I genotyping. Hum Immunol (2010) 1.33
Dual, HLA-B27 subtype-dependent conformation of a self-peptide. J Exp Med (2004) 1.31
Different effects of Nef-mediated HLA class I down-regulation on human immunodeficiency virus type 1-specific CD8(+) T-cell cytolytic activity and cytokine production. J Virol (2002) 1.31
Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape. PLoS One (2007) 1.30
Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1. J Virol (2012) 1.29
Human immunodeficiency virus type 1 (HIV-1)-specific CD8+-T-cell responses for groups of HIV-1-infected individuals with different HLA-B*35 genotypes. J Virol (2002) 1.28
Specific human leukocyte antigen class I and II alleles associated with hepatitis C virus viremia. Hepatology (2010) 1.28
Host genes associated with HIV/AIDS: advances in gene discovery. Trends Genet (2010) 1.25
Immunogenetics of HIV disease. Immunol Rev (2013) 1.25
Statistical resolution of ambiguous HLA typing data. PLoS Comput Biol (2008) 1.25
Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individuals. PLoS Genet (2007) 1.23
Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progression. PLoS Pathog (2007) 1.22
HLA-B*35-Px-mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses. J Exp Med (2009) 1.22
Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes. J Virol (2005) 1.21
The T-cell response to HIV. Cold Spring Harb Perspect Med (2012) 1.20
Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control. Nat Med (2013) 1.17
HLA-B alleles associate consistently with HIV heterosexual transmission, viral load, and progression to AIDS, but not susceptibility to infection. AIDS (2010) 1.17
Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs. J Immunol (2010) 1.15
Vaccine design for CD8 T lymphocyte responses. Cold Spring Harb Perspect Med (2011) 1.14
HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection. J Virol (2008) 1.13
The relation of HLA genotype to hepatitis C viral load and markers of liver fibrosis in HIV-infected and HIV-uninfected women. J Infect Dis (2011) 1.13
Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease. PLoS Genet (2012) 1.10
The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors. Nat Rev Immunol (2010) 1.10
Clinical, virologic, and immunologic correlates of HIV-1 intraclade B dual infection among men who have sex with men. AIDS (2012) 1.10
Human immunodeficiency virus vaccine trials. Cold Spring Harb Perspect Med (2012) 1.05
Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection. Clin Infect Dis (2009) 1.05
Immunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescents. AIDS (2007) 1.05
Vaccine-induced gag-specific T cells are associated with reduced viremia after HIV-1 infection. J Infect Dis (2013) 1.04
Impact of select immunologic and virologic biomarkers on CD4 cell count decrease in patients with chronic HIV-1 subtype C infection: results from Sinikithemba Cohort, Durban, South Africa. Clin Infect Dis (2009) 1.02
Haplotype-dependent HLA susceptibility to nasopharyngeal carcinoma in a Southern Chinese population. Genes Immun (2010) 1.01
Disparate associations of HLA class I markers with HIV-1 acquisition and control of viremia in an African population. PLoS One (2011) 1.01
HIV control through a single nucleotide on the HLA-B locus. J Virol (2012) 1.00
Immune pathogenesis of pediatric HIV-1 infection. Curr HIV/AIDS Rep (2006) 1.00
HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes. J Virol (2014) 1.00
A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Med (2010) 0.99
HLA class I allele promiscuity revisited. Immunogenetics (2011) 0.99
Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationships. PLoS One (2010) 0.98
The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition groove. PLoS Genet (2012) 0.98
Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule. J Immunol (2014) 0.97
The role of infant immune responses and genetic factors in preventing HIV-1 acquisition and disease progression. Clin Exp Immunol (2003) 0.95
Relationship of HIV reservoir characteristics with immune status and viral rebound kinetics in an HIV therapeutic vaccine study. AIDS (2014) 0.94
Churg-strauss syndrome as an unusual aetiology of stroke with haemorrhagic transformation in a patient with no cardiovascular risk factors. Case Rep Neurol (2011) 0.94
The influence of human leukocyte antigen class I alleles and their population frequencies on human immunodeficiency virus type 1 control among African Americans. Hum Immunol (2011) 0.93
Primate TNF promoters reveal markers of phylogeny and evolution of innate immunity. PLoS One (2007) 0.92
Newcastle disease virus expressing a dendritic cell-targeted HIV gag protein induces a potent gag-specific immune response in mice. J Virol (2010) 0.92
Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial. J Infect Dis (2011) 0.91
Human leukocyte antigen genotype and risk of HIV disease progression before and after initiation of antiretroviral therapy. J Virol (2011) 0.91
A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology (2015) 0.90
HLA class I, KIR, and genome-wide SNP diversity in the RV144 Thai phase 3 HIV vaccine clinical trial. Immunogenetics (2014) 0.90
HLA class I-mediated control of HIV-1 in the Japanese population, in which the protective HLA-B*57 and HLA-B*27 alleles are absent. J Virol (2012) 0.90
Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants. Retrovirology (2011) 0.89
Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response. Blood (2009) 0.89
Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope. J Virol (2012) 0.89
LILRB2 interaction with HLA class I correlates with control of HIV-1 infection. PLoS Genet (2014) 0.89
Human leukocyte antigen class I supertypes and HIV-1 control in African Americans. J Virol (2009) 0.88
Cell type-specific proteasomal processing of HIV-1 Gag-p24 results in an altered epitope repertoire. J Virol (2010) 0.88
Vaccine-induced HIV-specific CD8+ T cells utilize preferential HLA alleles and target-specific regions of HIV-1. J Acquir Immune Defic Syndr (2011) 0.88
Quantifying the impact of human immunodeficiency virus-1 escape from cytotoxic T-lymphocytes. PLoS Comput Biol (2010) 0.88
Autophagy and HIV. Semin Cell Dev Biol (2010) 0.87
The Role of CD4(+) and CD8(+) T Cells in Controlling HIV Infection. Curr Infect Dis Rep (2002) 0.87
Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa. J Virol (2010) 0.87
Impaired Nef function is associated with early control of HIV-1 viremia. J Virol (2014) 0.86
Correlates of spontaneous viral control among long-term survivors of perinatal HIV-1 infection expressing human leukocyte antigen-B57. AIDS (2010) 0.86
Structural insights into activation of antiviral NK cell responses. Immunol Rev (2012) 0.85
The emerging role of leukocyte immunoglobulin-like receptors (LILRs) in HIV-1 infection. J Leukoc Biol (2011) 0.85
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med (1996) 10.62
Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat Med (1996) 10.49
Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature (2000) 8.96
Resolution of the early placental mammal radiation using Bayesian phylogenetics. Science (2001) 8.68
Molecular phylogenetics and the origins of placental mammals. Nature (2001) 8.42
HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage. Science (1999) 8.11
The natural history of hepatitis C virus infection: host, viral, and environmental factors. JAMA (2000) 7.65
Mapping by admixture linkage disequilibrium in human populations: limits and guidelines. Am J Hum Genet (1994) 7.16
Association of cancer with AIDS-related immunosuppression in adults. JAMA (2001) 6.80
KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med (1996) 5.96
Tempting fate: control of communicable disease in England. BMJ (1993) 5.62
Mortality, CD4 cell count decline, and depressive symptoms among HIV-seropositive women: longitudinal analysis from the HIV Epidemiology Research Study. JAMA (2001) 5.52
Viral infections in short-term injection drug users: the prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses. Am J Public Health (1996) 5.45
Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes. Am J Hum Genet (1998) 5.24
Sex differences in HIV-1 viral load and progression to AIDS. Lancet (1998) 5.24
A canine distemper virus epidemic in Serengeti lions (Panthera leo). Nature (1996) 5.07
Self-reported antiretroviral therapy in injection drug users. JAMA (1998) 4.75
Determinants of retrovirus (HTLV-III) antibody and immunodeficiency conditions in homosexual men. Lancet (1984) 4.68
Sex differences in risk factors for hiv seroconversion among injection drug users: a 10-year perspective. Arch Intern Med (2001) 4.68
Risk factors for seroconversion to human immunodeficiency virus among male homosexuals. Results from the Multicenter AIDS Cohort Study. Lancet (1987) 4.33
Screening test for HTLV-III (AIDS agent) antibodies. Specificity, sensitivity, and applications. JAMA (1985) 4.26
The risk of Pneumocystis carinii pneumonia among men infected with human immunodeficiency virus type 1. Multicenter AIDS Cohort Study Group. N Engl J Med (1990) 4.25
Identification of an amplified, highly expressed gene in a human glioma. Science (1987) 4.21
Mechanism of met oncogene activation. Cell (1986) 4.20
Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization. Science (1986) 4.17
Genetic evidence for two species of elephant in Africa. Science (2001) 4.13
Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma. N Engl J Med (1996) 4.13
Persistence of viremia and the importance of long-term follow-up after acute hepatitis C infection. Hepatology (1999) 4.11
Correlates of hepatitis C virus infections among injection drug users. Medicine (Baltimore) (1995) 3.85
Prevalence of tuberculin positivity and skin test anergy in HIV-1-seropositive and -seronegative intravenous drug users. JAMA (1992) 3.81
Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Natl Cancer Inst (2000) 3.77
Numt, a recent transfer and tandem amplification of mitochondrial DNA to the nuclear genome of the domestic cat. J Mol Evol (1994) 3.71
Prevalence and incidence of hepatitis C virus infection among young adult injection drug users. J Acquir Immune Defic Syndr Hum Retrovirol (1998) 3.68
Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science (1998) 3.60
Predictors of the acquired immunodeficiency syndrome developing in a cohort of seropositive homosexual men. N Engl J Med (1987) 3.58
Time to initiating highly active antiretroviral therapy among HIV-infected injection drug users. AIDS (2001) 3.56
HLA and AIDS: a cautionary tale. Trends Mol Med (2001) 3.51
Serum HIV-1 RNA levels and time to development of AIDS in the Multicenter Hemophilia Cohort Study. JAMA (1996) 3.50
Trends in indigenous foodborne disease and deaths, England and Wales: 1992 to 2000. Gut (2002) 3.48
Comparative anchor tagged sequences (CATS) for integrative mapping of mammalian genomes. Nat Genet (1997) 3.47
Linkage disequilibrium in admixed populations: applications in gene mapping. J Hered (1994) 3.46
Conservation of the regulatory subunit for the Clp ATP-dependent protease in prokaryotes and eukaryotes. Proc Natl Acad Sci U S A (1990) 3.33
Three-year incidence of AIDS in five cohorts of HTLV-III-infected risk group members. Science (1986) 3.31
Interaction of human immunodeficiency virus type 1 and human herpesvirus type 8 infections on the incidence of Kaposi's sarcoma. J Infect Dis (2000) 3.20
Genetic basis for species vulnerability in the cheetah. Science (1985) 3.16
Transactivation induced by human T-lymphotropic virus type III (HTLV III) maps to a viral sequence encoding 58 amino acids and lacks tissue specificity. Virology (1986) 3.15
A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation. Nat Med (1998) 3.15
Molecular and geographic patterns of tuberculosis transmission after 15 years of directly observed therapy. JAMA (1998) 3.07
Changes in T-lymphocyte subsets in intravenous drug users with HIV-1 infection. JAMA (1992) 3.07
Markers for mapping by admixture linkage disequilibrium in African American and Hispanic populations. Am J Hum Genet (2001) 3.04
Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism. Proc Natl Acad Sci U S A (1984) 2.99
A genetic linkage map of microsatellites in the domestic cat (Felis catus). Genomics (1999) 2.99
Perinatal transmission of human immunodeficiency virus type 1 by pregnant women with RNA virus loads <1000 copies/ml. J Infect Dis (2001) 2.95
A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report from the Multicenter AIDS Cohort Study. Lancet (1990) 2.89
Expression of a polypeptide containing a dipeptide repeat is confined to the insect stage of Trypanosoma brucei. Nature (1987) 2.86
Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation. J Immunol (1996) 2.86
The Circuit Party Men's Health Survey: findings and implications for gay and bisexual men. Am J Public Health (2001) 2.83
Voluntary testing for human immunodeficiency virus (HIV) in a prison population with a high prevalence of HIV. Am J Epidemiol (1994) 2.81
The ets sequence from the transforming gene of avian erythroblastosis virus, E26, has unique domains on human chromosomes 11 and 21: both loci are transcriptionally active. Proc Natl Acad Sci U S A (1985) 2.80
A scan for linkage disequilibrium across the human genome. Genetics (1999) 2.79
New class I and II HLA alleles strongly associated with opposite patterns of progression to AIDS. J Immunol (1999) 2.76