An overview of the immune system.

PubWeight™: 1.73‹?› | Rank: Top 3%

🔗 View Article (PMID 11403834)

Published in Lancet on June 02, 2001

Authors

J Parkin1, B Cohen

Author Affiliations

1: Department of Immunology, St Bartholomew's and the Royal London Hospital School of Medicine and Dentistry, Queen Mary and Westfield College, West Smithfield, EC1A 7BE, London, UK. Jackie.Parkin@bartsandthelondon.nhs.uk

Associated clinical trials:

The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty | NCT03795649

Articles citing this

Information transduction capacity of noisy biochemical signaling networks. Science (2011) 2.95

Aspergillus infections in transplant recipients. Clin Microbiol Rev (2005) 2.82

Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions. J Pain (2007) 1.80

Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. J Leukoc Biol (2005) 1.80

The immune-body cytokine network defines a social architecture of cell interactions. Biol Direct (2006) 1.41

Gut microbiota composition is correlated to grid floor induced stress and behavior in the BALB/c mouse. PLoS One (2012) 1.21

A dialogue between the immune system and brain, spoken in the language of serotonin. ACS Chem Neurosci (2012) 1.20

Expanding the detectable HLA peptide repertoire using electron-transfer/higher-energy collision dissociation (EThcD). Proc Natl Acad Sci U S A (2014) 1.11

Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation. Clin Exp Immunol (2009) 0.98

Effect of labeling with iron oxide particles or nanodiamonds on the functionality of adipose-derived mesenchymal stem cells. PLoS One (2013) 0.89

Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function. Immunogenetics (2010) 0.88

Novel immune regulatory pathways and their role in immune reconstitution syndrome in organ transplant recipients with invasive mycoses. Eur J Clin Microbiol Infect Dis (2008) 0.88

Effects of temperature and salt concentration on the structural stability of human lymphotactin: insights from molecular simulations. J Am Chem Soc (2006) 0.88

Immunophenotyping of normal individuals classified on the basis of human dosha prakriti. J Ayurveda Integr Med (2014) 0.88

Cellular and molecular changes in orthodontic tooth movement. ScientificWorldJournal (2011) 0.87

Innate and Adaptive Immune Responses in Wound Epithelialization. Adv Wound Care (New Rochelle) (2014) 0.84

Increased expression of interleukin-6 family members and receptors in urinary bladder with cyclophosphamide-induced bladder inflammation in female rats. Front Neurosci (2011) 0.84

Immunostimulatory effects of the standardized extract of Tinospora crispa on innate immune responses in Wistar Kyoto rats. Drug Des Devel Ther (2015) 0.83

siRNA enhances DNA-mediated interferon lambda-1 response through crosstalk between RIG-I and IFI16 signalling pathway. Nucleic Acids Res (2013) 0.83

Increased prediction accuracy using a genomic feature model including prior information on quantitative trait locus regions in purebred Danish Duroc pigs. BMC Genet (2016) 0.83

Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice. Part Fibre Toxicol (2009) 0.83

Exaggerated expression of inflammatory mediators in vasoactive intestinal polypeptide knockout (VIP-/-) mice with cyclophosphamide (CYP)-induced cystitis. J Mol Neurosci (2008) 0.82

Toxicological effects of nickel chloride on IgA+ B Cells and sIgA, IgA, IgG, IgM in the intestinal mucosal immunity in broilers. Int J Environ Res Public Health (2014) 0.82

Prognostic role of lymphocyte to monocyte ratio for patients with cancer: evidence from a systematic review and meta-analysis. Oncotarget (2016) 0.82

The prognostic impact of preoperative blood monocyte count in pathological T3N0M0 rectal cancer without neoadjuvant chemoradiotherapy. Tumour Biol (2015) 0.81

Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder. BMC Psychiatry (2012) 0.80

Developments on drug discovery and on new therapeutics: highly diluted tinctures act as biological response modifiers. BMC Complement Altern Med (2011) 0.80

Cross talk between peritoneal macrophages and B-1 cells in vitro. PLoS One (2013) 0.80

High complement factor I activity in the plasma of children with autism spectrum disorders. Autism Res Treat (2011) 0.80

Fucoidin prevents Clostridium difficile toxin-A-induced ileal enteritis in mice. Dig Dis Sci (2007) 0.79

Correlation of cytokine level with the severity of severe fever with thrombocytopenia syndrome. Virol J (2017) 0.78

An Overview of Pathogen Recognition Receptors for Innate Immunity in Dental Pulp. Mediators Inflamm (2015) 0.78

DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nat Commun (2015) 0.78

Short-interference RNAs: becoming medicines. EXCLI J (2015) 0.78

TUNABLE COMPLEMENT ACTIVATION BY PARTICLES WITH VARIABLE SIZE AND Fc DENSITY. Nano Life (2013) 0.78

Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials. Front Plant Sci (2015) 0.78

Effects of cortisol on the intestinal mucosal immune response during cohabitant challenge with IPNV in Atlantic salmon (Salmo salar). PLoS One (2014) 0.77

Regulating Biocompatibility of Carbon Spheres via Defined Nanoscale Chemistry and a Careful Selection of Surface Functionalities. Sci Rep (2015) 0.77

Knockout of Toll-Like Receptors 2 and 4 Prevents Renal Ischemia-Reperfusion-Induced Cardiac Hypertrophy in Mice. PLoS One (2015) 0.77

Prognostic value of a systemic inflammatory response index in metastatic renal cell carcinoma and construction of a predictive model. Oncotarget (2016) 0.76

The human immune system's response to carcinogenic and other infectious agents transmitted by mosquito vectors. Parasitol Res (2016) 0.76

The impact of maternal obesity during pregnancy on offspring immunity. Mol Cell Endocrinol (2015) 0.76

Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival. Ecol Evol (2016) 0.76

Recent Developments of Liposomes as Nanocarriers for Theranostic Applications. Theranostics (2016) 0.76

Effects of corticosterone and dietary energy on immune function of broiler chickens. PLoS One (2015) 0.76

Insights into the innate immunome of actiniarians using a comparative genomic approach. BMC Genomics (2016) 0.76

Comparative Functional Analysis of 12 Mammalian IFN-λ4 Orthologs. J Interferon Cytokine Res (2015) 0.76

In Vivo Interrelationship between Insulin Resistance and Interferon Gamma Production: Protective and Therapeutic Effect of Berberine. Evid Based Complement Alternat Med (2016) 0.75

Cell Therapy Strategies to Combat Immunosenescence. Organogenesis (2015) 0.75

IL-15 regulates migration, invasion, angiogenesis and genes associated with lipid metabolism and inflammation in prostate cancer. PLoS One (2017) 0.75

The immunomodulatory effects of Sutherlandia frutescens extracts in human normal peripheral blood mononuclear cells. Afr J Tradit Complement Altern Med (2012) 0.75

MYC in Regulating Immunity: Metabolism and Beyond. Genes (Basel) (2017) 0.75

Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut. Crit Rev Biochem Mol Biol (2016) 0.75

Preparation and characterization of different liposomal formulations containing P5 HER2/neu-derived peptide and evaluation of their immunological responses and antitumor effects. Iran J Basic Med Sci (2015) 0.75

Molecular Characteristics of High-Dose Melphalan Associated Oral Mucositis in Patients with Multiple Myeloma: A Gene Expression Study on Human Mucosa. PLoS One (2017) 0.75

A cognitive computational model inspired by the immune system response. Biomed Res Int (2014) 0.75

Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto. Sci Rep (2016) 0.75

Fc microparticles can modulate the physical extent and magnitude of complement activity. Biomater Sci (2017) 0.75

Conjugated Bilirubin Differentially Regulates CD4+ T Effector Cells and T Regulatory Cell Function through Outside-In and Inside-Out Mechanisms: The Effects of HAV Cell Surface Receptor and Intracellular Signaling. Mediators Inflamm (2016) 0.75

The effect of polyphenols on cytokine and granulocyte response to resistance exercise. Physiol Rep (2016) 0.75

Rubicon modulates antiviral type I IFN signaling by targeting IRF3 dimerization. J Virol (2017) 0.75

[Biologicals: a new therapeutic approach for inflammatory diseases]. Internist (Berl) (2004) 0.75

CK12a, a CCL19-like Chemokine That Orchestrates both Nasal and Systemic Antiviral Immune Responses in Rainbow Trout. J Immunol (2017) 0.75

Potentiation of Natural Killer Cells for Cancer Immunotherapy: A Review of Literature. Front Immunol (2017) 0.75

In vitro effects of binuclear (η (6)-p-cymene)ruthenium(II) complex containing bridging bis(nicotinate)-polyethylene glycol ester ligand on differentiation pathways of murine Th lymphocytes activated by T cell mitogen. J Biol Inorg Chem (2015) 0.75

Long non-coding RNA SeT and miR-155 regulate the Tnfα gene allelic expression profile. PLoS One (2017) 0.75

Role of Interferons in the Development of Diagnostics, Vaccines, and Therapy for Tuberculosis. J Immunol Res (2017) 0.75

Articles by these authors

(truncated to the top 100)

National health and nutrition examination I--epidemiologic follow-up survey. Public Health Rep (1983) 5.42

Purification and characterization of phosphoinositide 3-kinase from rat liver. J Biol Chem (1990) 4.75

10 years after NHANES I: report of initial followup, 1982-84. Public Health Rep (1986) 4.11

Diagnosis of human lymphoma with monoclonal antileukocyte antibodies. N Engl J Med (1983) 3.63

HIV-associated neurologic disease incidence changes:: Multicenter AIDS Cohort Study, 1990-1998. Neurology (2001) 3.55

Mitochondrial myopathy caused by long-term zidovudine therapy. N Engl J Med (1990) 3.52

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT. EMBO J (1998) 3.13

Failure of cytarabine in progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. AIDS Clinical Trials Group 243 Team. N Engl J Med (1998) 2.99

Shortage of organs for transplantation. BMJ (1996) 2.97

Chronic bone marrow failure due to persistent B19 parvovirus infection. N Engl J Med (1987) 2.93

The human interferon alpha/beta receptor: characterization and molecular cloning. Cell (1994) 2.63

A chart review study of late-onset and early-onset schizophrenia. Am J Psychiatry (1989) 2.44

Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2. Nature (1996) 2.34

Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs. Nature (1994) 2.33

Ocular motor function in motor neuron disease. Neurology (1992) 2.27

Reactions of adult and teenaged smokers to the Massachusetts tobacco tax. Am J Public Health (1998) 2.23

Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia. Neurology (2004) 2.18

Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1. Proc Natl Acad Sci U S A (2001) 2.10

HIV neuropathy natural history cohort study: assessment measures and risk factors. Neurology (2006) 2.06

Longitudinally preserved psychomotor performance in long-term asymptomatic HIV-infected individuals. Neurology (2007) 2.05

Velocity storage in the vestibulo-ocular reflex arc (VOR). Exp Brain Res (1979) 2.04

Vascular risk factors, HIV serostatus, and cognitive dysfunction in gay and bisexual men. Neurology (2009) 2.00

Persistent B19 parvovirus infection as a cause of severe chronic anaemia in children with acute lymphocytic leukaemia. Lancet (1988) 1.97

Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less. Cell (1992) 1.91

Immunisation of monkeys (Macaca fascicularis) with antigens purified from Streptococcus mutans. Br Dent J (1982) 1.81

King Henry 8th and the barber surgeons. The story of the Holbein cartoon. Ann R Coll Surg Engl (1967) 1.72

Immunization against dental caries. Br Dent J (1975) 1.71

Loss of visual suppression of vestibular nystagmus after flocculus lesions. Brain Res (1974) 1.65

Olmsted syndrome. Case report and identification of a keratin abnormality. Arch Dermatol (1996) 1.62

Quantitative analysis of the velocity characteristics of optokinetic nystagmus and optokinetic after-nystagmus. J Physiol (1977) 1.62

Signs of central nervous system dysfunction in obsessive-compulsive disorder. Arch Gen Psychiatry (1990) 1.57

Vertical glaze paralysis and the rostral interstitial nucleus of the medial longitudinal fasciculus. Brain (1982) 1.56

Cloning DNA sequences from influenza viral RNA segments. Proc Natl Acad Sci U S A (1980) 1.54

Growth and development of the pediatric cervical spine documented radiographically. J Bone Joint Surg Am (2001) 1.52

Dynamic modification of the vestibulo-ocular reflex by the nodulus and uvula. Science (1985) 1.51

Neurological outcomes in late HIV infection: adverse impact of neurological impairment on survival and protective effect of antiviral therapy. AIDS Clinical Trial Group and Neurological AIDS Research Consortium study team. AIDS (1999) 1.48

Combination antiretroviral therapy improves psychomotor speed performance in HIV-seropositive homosexual men. Multicenter AIDS Cohort Study (MACS). Neurology (1999) 1.46

Countries' donation performance in perspective: time for more accurate comparative methodologies. Am J Transplant (2007) 1.45

Pregnancy complicated by vesical calculus and vesicocutaneous fistula. Am J Obstet Gynecol (1997) 1.44

Inter-rater reliability of a clinical staging of HIV-associated cognitive impairment. Neurology (2003) 1.44

Radiographic changes in the knee after meniscal transplantation. An experimental study in a sheep model. Am J Sports Med (1996) 1.43

A human IFN-beta 1 gene deleted of promoter sequences upstream from the TATA box is controlled post-transcriptionally by dsRNA. Nucleic Acids Res (1984) 1.43

Zinc-responsive dermatosis in dogs: 41 cases and literature review. Vet Dermatol (2001) 1.41

Mumps surveillance in England and Wales supports introduction of two dose vaccination schedule. Commun Dis Rep CDR Rev (1997) 1.40

Progressive multifocal leukoencephalopathy in AIDS: are there any MR findings useful to patient management and predictive of patient survival? AIDS Clinical Trials Group, 243 Team. AJNR Am J Neuroradiol (2000) 1.40

Prospective study of patients' refusal of antipsychotic medication under a physician discretion review procedure. Am J Psychiatry (1997) 1.39

The effects of exposure to chewing tobacco on the oral mucosa of monkey and man. A histological and ultrastructural study. Ann R Coll Surg Engl (1971) 1.39

A comparison of pulmonary function in male smokers and nonsmokers. Am Rev Respir Dis (1976) 1.39

Results of acute heart retransplantation. Lancet (1991) 1.39

Vestibular control of sympathetic activity. An otolith-sympathetic reflex in humans. Exp Brain Res (2002) 1.36

Causes of morbilliform rash in a highly immunised English population. Arch Dis Child (2002) 1.35

Interaction of the body, head, and eyes during walking and turning. Exp Brain Res (2001) 1.35

Late cognitive and radiographic changes related to radiotherapy: initial prospective findings. Neurology (2002) 1.35

Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma. Proc Natl Acad Sci U S A (2000) 1.33

Control of spatial orientation of the angular vestibuloocular reflex by the nodulus and uvula. J Neurophysiol (1998) 1.31

Effects of walking velocity on vertical head and body movements during locomotion. Exp Brain Res (1999) 1.31

The effect of pulmonary impairment on all-cause mortality in a national cohort. Chest (1993) 1.27

Parafoveal retinal telangiectasis. Light and electron microscopy studies. Trans Ophthalmol Soc U K (1980) 1.27

Poor results of the Ribbed Hip System for cementless replacement. J Bone Joint Surg Br (1995) 1.27

Markers of immune activation and viral load in HIV-associated sensory neuropathy. Neurology (2005) 1.25

New mode of operating a magnetized coaxial plasma gun for injecting magnetic helicity into a spheromak. Phys Rev Lett (2003) 1.25

Longitudinal sliding of the median nerve in patients with carpal tunnel syndrome. J Hand Surg Br (2003) 1.24

Unit activity in the pontine reticular formation associated with eye movements. Brain Res (1972) 1.22

A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team. Neurology (1998) 1.21

Acquired immunodeficiency syndrome in the child of a haemophiliac. Lancet (1985) 1.20

A molecular map of T cell development. Immunity (1998) 1.19

Endometrial cyst of the liver. Am J Gastroenterol (1986) 1.18

Sp1/egr-like zinc-finger protein required for endoderm specification and germ-layer formation in Drosophila. Nature (1994) 1.18

Effect of HLA-A and HLA-B matching on survival of grafts and recipients after renal transplantation. N Engl J Med (1982) 1.18

Biochemical and genetic factors influencing drug metabolism. Influence of hepatic microsomal mixed function oxidation reactions on cellular metabolic control. Metabolism (1971) 1.17

A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity. J Virol (1990) 1.16

Eye movements induced by stimulation of the pontine reticular formation: evidence for integration in oculomotor pathways. Exp Neurol (1972) 1.15

Aspiration as a guide to sepsis in revision total hip arthroplasty. J Arthroplasty (1996) 1.14

Treatment of autoimmune disease by intense immunosuppressive conditioning and autologous hematopoietic stem cell transplantation. Blood (1998) 1.11

Fluorescence spectroscopy for detection of malignancy: H-ras overexpressing fibroblasts as a model. J Biochem Biophys Methods (2001) 1.11

p53 mutations in cervical carcinogenesis--low frequency and lack of correlation with human papillomavirus status. Br J Cancer (1994) 1.11

Effects of vestibular nuclei lesions on vestibulo-ocular reflexes and posture in monkeys. Acta Otolaryngol Suppl (1973) 1.11

Response to systemic HIV viral load suppression correlates with psychomotor speed performance. Neurology (2003) 1.10

Cerebrotendinous xanthomatosis: reduced serum 26-hydroxycholesterol. J Lipid Res (1982) 1.10

Immunisation against dental caries: further studies. Br Dent J (1979) 1.10

A clinical program for in-service nurses: A preliminary report. Bull Med Libr Assoc (1980) 1.10

Model-based study of the human cupular time constant. J Vestib Res (1999) 1.09

Sledging injuries. BMJ (1991) 1.09

Perception of tilt (somatogravic illusion) in response to sustained linear acceleration during space flight. Exp Brain Res (2001) 1.09

Dental caries in experimental monkeys. A pilot study. Br Dent J (1966) 1.08

Effects of gravity on rotatory nystagmus in monkeys. Ann N Y Acad Sci (1981) 1.08

Tumours of the jaw in West Africa. A review of 256 patients. Br J Surg (1967) 1.07

Role of the flocculus and paraflocculus in optokinetic nystagmus and visual-vestibular interactions: effects of lesions. Exp Brain Res (1983) 1.07

Eye movements induced by electric stimulation of the cerebellum in the alert cat. Exp Neurol (1965) 1.06

Lesions of the pontine tegmentum and conjugate gaze paralysis. Arch Neurol (1971) 1.06

Visual suppression of vestibular nystagmus in rhesus monkeys. Brain Res (1974) 1.06

Antibody responses to antigens of Streptococcus mutans in monkeys (Macaca fascicularis) immunized against dental caries. J Gen Microbiol (1983) 1.04

Splenic abscess due to Clostridium difficile. J Infect Dis (1983) 1.03

Comparative Studies in Periodontal Disease [Abridged]. Proc R Soc Med (1960) 1.02

Commercial factor VIII associated hepatitis, 1974-75, in the United Kingdom: a retrospective survey. J Hyg (Lond) (1978) 1.02

Hepatic endometrioma. J Clin Ultrasound (1986) 1.02

Megalocornea associated with multiple skeletal anomalies: a new genetic syndrome? J Genet Hum (1973) 1.02

Raphe nucleus of the pons containing omnipause neurons of the oculomotor system in the monkey, and its homologue in man. J Comp Neurol (1988) 1.02

Distal-less is a downstream gene of Deformed required for ventral maxillary identity. Development (1993) 1.02

Habituation and adaptation of the vestibuloocular reflex: a model of differential control by the vestibulocerebellum. Exp Brain Res (1992) 1.01